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Soft tissue augmentation

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https://www.readbyqxmd.com/read/28817244/key-developments-that-impacted-the-field-of-mechanobiology-and-mechanotransduction
#1
Michelle Wall, David Butler, Alicia El Haj, Josephine C Bodle, Elizabeth G Loboa, Albert J Banes
Advances in mechanobiology have evolved through insights from multiple disciplines including structural engineering, biomechanics, vascular biology, and orthopaedics. In this paper, we reviewed the impact of key reports related to the study of applied loads on tissues and cells and the resulting signal transduction pathways. We addressed how technology has helped advance the burgeoning field of mechanobiology (over 33,600 publications from 1970-2016). We analyzed the impact of critical ideas and then determined how these concepts influenced the mechanobiology field by looking at the citation frequency of these reports as well as tracking how the overall number of citations within the field changed over time...
August 17, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28817126/principles-for-vertical-ridge-augmentation-in-the-atrophic-posterior-mandible-a-technical-review
#2
Istvan A Urban, Alberto Monje, Jaime Lozada, Hom-Lay Wang
Guided bone regeneration has become more predictable due to advances in material sciences. Nevertheless, vertical ridge augmentation (VRA) remains a potential challenge due to the complexity of soft tissue management. This becomes more complicated in the posterior atrophic mandible due to limited access and poorer blood supply. As such, a number of critical elements must be taken into consideration in treatment planning. Anatomical structures potentially jeopardize intraoperative adverse events such as bleeding or neurosensory disturbances...
September 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28816718/double-composite-tissue-z-plasty-technique-for-anatomical-restoration-of-severe-nasal-deformity-in-secondary-unilateral-cleft-lip
#3
Jiao Wei, Tanja Herrler, Hua Xu, Qingfeng Li, Chuanchang Dai
BACKGROUND: Patients with secondary unilateral cleft lip are regularly affected by serious nasal deformities especially of the alar and nasal floor. A large number of techniques for correction have been published, but symmetrical restoration of severe nasal deformation is difficult to achieve. We propose an innovative approach for anatomical restoration for this entity of nasal deformities to achieve long-term symmetrical appearance and muscular function. METHODS: A total of 68 patients with severe nasal deformity due to secondary unilateral cleft lip underwent reconstructive surgery using a double composite tissue Z-plasty technique for anatomical restoration of cartilage, muscle, and soft tissue layers...
August 14, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28804933/chemical-functionalization-of-polysaccharides-towards-biocompatible-hydrogels-for-biomedical-applications
#4
Andreas Kirschning, Gerald Dräger, Nick Dibbert
Hydrogels have emerged as a highly interdisciplinary topic as they play a significant role for a vast number of applications. They have been studied extensively as materials for contact lenses, wound dressing and as filler material in soft-tissue augmentation, in which classical polymer backbones such as hydroxyethylmethacrylate (HEMA) are typically employed. More recently, polysaccharides have received attention, particularly in the fields of regenerative medicine and tissue engineering, as ideal candidate materials for artificial extracellular matrices (ECM)...
August 13, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28802415/augmentation-of-intramedullary-nailing-in-unstable-intertrochanteric-fractures-using-cerclage-wire-and-lag-screws-a-comparative-study
#5
Sunil Govind Kulkarni, Sushrut Sudhir Babhulkar, Sujay Milind Kulkarni, Govind Shivram Kulkarni, Madhura Sujay Kulkarni, Raviraj Patil
BACKGROUND: Unstable intertrochanteric fractures present a challenge to orthopaedic surgeons, with varied geometry of the fractures and a wide choice of implants and techniques. The patients are usually osteoporotic, with multiple co-morbidities and poor tolerance for complications and re-operations. Lateral wall reconstruction and stability of the trochanteric fragments are considered important in providing a better outcome of these difficult injuries. We present a technique of lateral wall and trochanteric reconstruction using Cerclage wires and lag screws in the greater trochanter in addition to intramedullary nailing, and the radiological and functional outcome of this technique of augmentation...
August 2017: Injury
https://www.readbyqxmd.com/read/28792430/component-separation-technique-for-repair-of-massive-abdominal-wall-defects-at-a-pediatric-hospital
#6
James D Vargo, Michael T Larsen, Gregory D Pearson
BACKGROUND: Massive defects of the abdominal wall are commonly repaired with the component separation technique (CST) when insufficient tissue exists to close the defect primarily. Although the utility of CST has been documented in cases of large ventral hernias in adults, its application to congenital and acquired defects in pediatric patients has been largely unreported. This study is a retrospective case series discussing the success of CST at a large pediatric hospital. METHODS: Seven patients with massive abdominal wall defects, including ventral hernia and omphalocele, repaired with CST at a pediatric hospital were identified as candidates...
November 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28790361/small-molecule-mediated-tribbles-homolog-3-promotes-bone-formation-induced-by-bone-morphogenetic-protein-2
#7
Jiabing Fan, Joan Pi-Anfruns, Mian Guo, Dan C S Im, Zhong-Kai Cui, Soyon Kim, Benjamin M Wu, Tara L Aghaloo, Min Lee
Although bone morphogenetic protein-2 (BMP2) has demonstrated extraordinary potential in bone formation, its clinical applications require supraphysiological milligram-level doses that increase postoperative inflammation and inappropriate adipogenesis, resulting in well-documented life-threatening cervical swelling and cyst-like bone formation. Recent promising alternative biomolecular strategies are toward promoting pro-osteogenic activity of BMP2 while simultaneously suppressing its adverse effects. Here, we demonstrated that small molecular phenamil synergized osteogenesis and bone formation with BMP2 in a rat critical size mandibular defect model...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28778112/-soft-tissue-fillers-state-of-the-art-and-future-perspectives
#8
Matthias M Aitzetmüller, Inesa Sukhova, Georg M Huemer, Hans-Guenther Machens, Jan-Thorsten Schantz, Dominik Duscher
In addition to cosmetic use, filler materials are frequently employed for reconstruction of contour defects. Scars and tissue defects after accidents, surgery and irradiation are also ideal indications for injectables. The ideal filler should be easy to inject, easy to form, and should remain in the body as long as possible. It should neither be allergenic or carcinogenic nor susceptible to infections or biofilms, but still potentially reversible, temperature-stable, and cheap. There is still no augmentation material that fulfils all of these criteria...
August 4, 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28777920/complications-associated-with-the-use-of-recombinant-human-bone-morphogenic-protein-2-in-ridge-augmentation-a-case-report
#9
Panagiotis Dragonas, Charles Palin, Saba Khan, Praveen Gajendrareddy, Whitney Weiner
This case report aims to describe in detail a complication associated with resorption of regenerated bone following implant placement and ridge augmentation using rhBMP-2 in combination with allograft and xenograft. Bilateral maxillary sinus and ridge augmentation procedures were completed using rhBMP-2 combined with allograft and xenograft. Five months later, significant bone augmentation was achieved which allowed for the placement of 4 implants. Upon stage 2 surgery, significant dehiscence was noted in all implants...
August 4, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28777156/deep-transverse-metacarpal-ligament-reconstruction-using-suture-button-and-a1-pulley
#10
Joshua Piercey, Paul McEniery, Nicholas Green
Rupture of the deep transverse metacarpal ligament (DTML) can result in pain, impaired grip strength, and undermine functional performance of the hand. We describe the case of a patient whose right hand came into contact with a boat propeller. He sustained a complete disruption of the DTML between the second and third ray in addition to soft tissue injury and open metacarpal fractures. Although other techniques describe a reconstruction of the DTML, our technique describes an adjunctive technique that strongly augments the A1 pulley reconstruction and nullifies the requirements of palmaris longus graft...
August 3, 2017: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/28770415/measurement-accuracy-of-alveolar-soft-tissue-contour-using-a-laboratory-laser-scanner
#11
Daisuke Ueno, Mariko Kobayashi, Kenko Tanaka, Tsuneaki Watanabe, Tetsuro Nakamura, Kazuhiko Ueda, Takatoshi Nagano
Steric analysis of morphological changes is important for evaluation of surgical techniques. This study was performed to assess the measurement accuracy of alveolar soft tissue contour with a laboratory laser scanner. The width of the maxillary alveolar soft tissue contour was evaluated in 20 volunteers. Measurement sites were established in the alveolar soft tissue contour of the maxillary incisor and canine areas. Each site was evaluated by direct measurement with a microcaliper for each subject (DMM) and image measurement using a laboratory laser scanner (IMS)...
August 2, 2017: Odontology
https://www.readbyqxmd.com/read/28755303/-degeneration-of-the-posterior-tibial-tendon-established-and-new-concepts
#12
REVIEW
Markus Walther
BACKGROUND: The most common cause of degeneration of the posterior tibial tendon is a congenital valgus deformity of the calcaneus. Other associated pathologies are forefoot supination, forefoot abduction and shortening of the gastrocnemius muscle. DIAGNOSTICS: Loaded x‑rays of the foot in three planes as well as the hindfoot alignment view enable evaluation of the axis of the foot under static loading conditions. The posterior tibial tendon can be imaged with ultrasound and magnetic resonance imaging (MRI)...
July 28, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28753574/functional-characterization-of-lysine-specific-demethylase-2-lsd2-kdm1b-in-breast-cancer-progression
#13
Lin Chen, Shauna N Vasilatos, Ye Qin, Tiffany A Katz, Chunyu Cao, Hao Wu, Nilgun Tasdemir, Kevin M Levine, Steffi Oesterreich, Nancy E Davidson, Yi Huang
Flavin-dependent histone demethylases govern histone H3K4 methylation and act as important chromatin modulators that are extensively involved in regulation of DNA replication, gene transcription, DNA repair, and heterochromatin gene silencing. While the activities of lysine-specific demethylase 1 (LSD1/KDM1A) in facilitating breast cancer progression have been well characterized, the roles of its homolog LSD2 (KDM1B) in breast oncogenesis are relatively less understood. In this study, we showed that LSD2 protein level was significantly elevated in malignant breast cell lines compared with normal breast epithelial cell line...
July 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28750949/a-machine-learning-approach-for-real-time-modelling-of-tissue-deformation-in-image-guided-neurosurgery
#14
Michele Tonutti, Gauthier Gras, Guang-Zhong Yang
OBJECTIVES: Accurate reconstruction and visualisation of soft tissue deformation in real time is crucial in image-guided surgery, particularly in augmented reality (AR) applications. Current deformation models are characterised by a trade-off between accuracy and computational speed. We propose an approach to derive a patient-specific deformation model for brain pathologies by combining the results of pre-computed finite element method (FEM) simulations with machine learning algorithms...
July 24, 2017: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/28750118/modification-of-chin-projection-and-aesthetics-with-onabotulinumtoxina-injection
#15
Amy K Hsu, Andrew S Frankel
Importance: Because of the soft-tissue envelope and the dimensional complexity of the muscular contraction of the mentalis muscle, the projection and shape of the chin is not determined by only the bony projection. In a subset of patients with a seemingly underprojected chin, a hyperactive, high-riding mentalis muscle contributes to a blunted chin contour. Objective: To evaluate the use of onabotulinumtoxinA (botulinum toxin A) for improving chin aesthetics in patients with an underprojected bony chin and a high-riding hyperactive mentalis muscle...
July 27, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28748521/clinical-outcome-of-alveolar-ridge-augmentation-with-individualized-cad-cam-produced-titanium-mesh
#16
K Sagheb, E Schiegnitz, M Moergel, C Walter, B Al-Nawas, W Wagner
BACKGROUND: The augmentation of the jaw has been and continues to be a sophisticated therapy in implantology. Modern CAD-CAM technologies lead to revival of old and established augmentation techniques such as the use of titanium mesh (TM) for bone augmentation. The aim of this retrospective study was to evaluate the clinical outcome of an individualized CAD-CAM-produced TM based on the CT/DVT-DICOM data of the patients for the first time. METHODS: In 17 patients, 21 different regions were augmented with an individualized CAD-CAM-produced TM (Yxoss CBR®, Filderstadt, Germany)...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28746209/pedicled-buccal-fat-pad-for-the-augmentation-of-facial-depression-deformity-a-case-report
#17
Seiji Komatsu, Kou Ikemura, Yoshihiro Kimata
RATIONALE: Tissue augmentation of facial depression deformities can be achieved by volume replacement with autologous fat injection, dermal filler injection, etc. Here, we report a case of tissue augmentation of a facial depression deformity using a pedicled buccal fat pad (BFP). PATIENT CONCERNS: A 64-year-old woman was referred with a chief complaint of facial depression deformity. DIAGNOSES: Her molars had been removed at another hospital 12 years prior to this referral, and the patient suffered from a left cheek depression deformity as a sequela of a postextraction infection...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28745027/histologic-and-histomorphometric-assessment-of-sinus-floor-augmentation-with-beta-tricalcium-phosphate-alone-or-in-combination-with-pure-platelet-rich-plasma-or-platelet-rich-fibrin-a-randomized-clinical-trial
#18
Songül Cömert Kılıç, Metin Güngörmüş, Seçil Nazife Parlak
BACKGROUND: The potential effects of adding pure platelet-rich plasma (P-PRP) or platelet-rich fibrin (PRF) to beta-tricalcium phosphate (β-TCP) graft substitute on bone formation and regeneration after maxillary sinus-floor elevation remains unclear. PURPOSE: To compare the histologic and histomorphometric outcomes of maxillary sinus-floor augmentation among β-TCP alone, P-PRP-mixed β-TCP, and PRF-mixed β-TCP. MATERIAL AND METHODS: In this randomized clinical trial, elevated sinus cavities were grafted with β-TCP (the control group), P-PRP-mixed β-TCP (the P-PRP group), and PRF-mixed β-TCP (PRF group)...
July 26, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28739500/breast-implant-capsule-associated-squamous-cell-carcinoma-a-report-of-two-cases
#19
Daniel L Olsen, Gary L Keeney, Beiyun Chen, Daniel W Visscher, Jodi M Carter
The use of prosthetic implants for breast augmentation has become commonplace. While implants do not increase the risk of conventional mammary carcinoma, they are rarely associated with anaplastic large cell lymphoma. We report two cases of breast implant capsule-associated squamous cell carcinoma with poor clinical outcomes. Both patients (56-year-old female and 81-year-old female) had long-standing implants (>25years) and presented with acute unilateral breast enlargement. In both cases, squamous cell carcinoma arose in (focally dysplastic) squamous epithelium-lined breast implant capsules, and widely invaded surrounding breast parenchyma or chest wall...
July 21, 2017: Human Pathology
https://www.readbyqxmd.com/read/28736606/mandibular-bone-regeneration-after-bone-slat-technique
#20
Salvatore D'Amato, Gianpaolo Tartaro, Angelo Itro, Mario Santagata
BACKGROUND: The reconstruction of alveolar ridges for implant placement is still a challenging surgical procedure, especially in the case of extensive vertical and horizontal bone atrophy. OBJECTIVE: The objective of the present study was to evaluate the quantity and quality of newly regenerated bone; clinically by means of direct clinical measuring, ridges augmented by autogenous cortical bone associated with autogenous particulate bone graft in the posterior lower jaw defect...
January 2017: Annali di Stomatologia
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