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https://www.readbyqxmd.com/read/29144022/collagen-a-review-on-its-sources-and-potential-cosmetic-applications
#1
REVIEW
María Isabela Avila Rodríguez, Laura G Rodríguez Barroso, Mirna Lorena Sánchez
Collagen is a fibrillar protein that conforms the conjunctive and connective tissues in the human body, essentially skin, joints, and bones. This molecule is one of the most abundant in many of the living organisms due to its connective role in biological structures. Due to its abundance, strength and its directly proportional relation with skin aging, collagen has gained great interest in the cosmetic industry. It has been established that the collagen fibers are damaged with the pass of time, losing thickness and strength which has been strongly related with skin aging phenomena [Colágeno para todo...
November 16, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29143901/combined-vertebral-augmentation-and-radiofrequency-ablation-in-the-management-of-spinal-metastases-an-update
#2
REVIEW
Ning Mao Kam, Julian Maingard, Hong Kuan Kok, Dinesh Ranatunga, Duncan Brooks, William C Torreggiani, Peter L Munk, Michael J Lee, Ronil V Chandra, Hamed Asadi
Spinal metastases are the most commonly encountered tumour of the spine, occurring in up to 40% of patients with cancer. Each year, approximately 5% of cancer patients will develop spinal metastases. This number is expected to increase as the life expectancy of cancer patients increases. Patients with spinal metastases experience severe and frequently debilitating pain, which often decreases their remaining quality of life. With a median survival of less than 1 year, the goals of treatment in spinal metastases are reducing pain, improving or maintaining level of function and providing mechanical stability...
November 16, 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/29140095/a-customized-healing-abutment-for-immediate-and-delayed-implant-cases
#3
Lambert J Stumpel, Chandur Wadhwani
Anatomically contoured healing abutments have been shown to contain and protect slow-resorbing substitution grafts, resulting in bone and soft-tissue volume augmentation. Even in healed sites customized healing abutments have demonstrated favorable outcomes compared to standard healing abutments. Through two separate cases, this article describes a technique that enables simple chairside fabrication of precisely contoured customized healing abutments and exact 3-dimensional intraoral positioning. With this technique, the soft tissues upon maturation closely resemble the natural root contour, which allows for the generation of esthetic and functional implant-supported restorations...
November 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/29137219/functional-characterization-of-lysine-specific-demethylase-2-lsd2-kdm1b-in-breast-cancer-progression
#4
Lin Chen, Shauna N Vasilatos, Ye Qin, Tiffany A Katz, Chunyu Cao, Hao Wu, Nilgun Tasdemir, Kevin M Levine, Steffi Oesterreich, Nancy E Davidson, Yi Huang
Flavin-dependent histone demethylases govern histone H3K4 methylation and act as important chromatin modulators that are extensively involved in regulation of DNA replication, gene transcription, DNA repair, and heterochromatin gene silencing. While the activities of lysine-specific demethylase 1 (LSD1/KDM1A) in facilitating breast cancer progression have been well characterized, the roles of its homolog LSD2 (KDM1B) in breast oncogenesis are relatively less understood. In this study, we showed that LSD2 protein level was significantly elevated in malignant breast cell lines compared with normal breast epithelial cell line...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29131778/adventures-and-misadventures-in-plastic-surgery-and-soft-tissue-implants
#5
Dana J Lin, Tony T Wong, Gina A Ciavarra, Jonathan K Kazam
Soft-tissue augmentation and implants are increasingly seen by the radiologist as more techniques emerge for a variety of indications and locations. Some surgical and implant procedures are performed for purely cosmetic reasons in otherwise healthy patients seeking to improve their body image, and some are performed for reconstruction after cancer or other chronic illnesses. Abdominoplasty, liposuction, and autologous fat grafting can be performed for abdominal and gluteal contouring. Injection of liquid injectable silicone has historically been fraught with legal issues, although it continues to be used for augmentation in a variety of anatomic locations...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29097172/beyond-250-a-comprehensive-strategy-to-maximize-the-operative-experience-for-junior-residents
#6
James M Healy, Mark W Maxfield, Daniel G Solomon, Walter E Longo, Peter S Yoo
OBJECTIVES: Among surgical educators, duty-hour restrictions led to concern regarding the adequacy of operative experience during residency, especially for junior residents. The American Board of Surgery recently instituted guidelines mandating "a minimum of 250 operations by the end of the PGY-2 year". A series of programmatic and institutional changes were implemented at our institution to augment the junior resident operative experience and to exceed compliance with this mandate. METHODS: Operative data from Accreditation Council for Graduate Medical Education case logs for categorical and nondesignated preliminary interns from our large academic surgical residency were identified for 5 consecutive academic years, 2011 until 2016...
October 30, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/29091485/sensitivity-and-specificity-of-skyline-and-carpal-shoot-through-fluoroscopic-views-of-volar-plate-fixation-of-the-distal-radius-a-cadaveric-investigation-of-dorsal-cortex-screw-penetration
#7
T Kyle Stoops, Brandon G Santoni, Nicolette M Clark, Amy A Bauer, Christopher Shoji, Francisco Schwartz-Fernandes
BACKGROUND: Volar plate fixation of distal radius fractures can result in soft tissue injuries. Abnormal contour of the dorsal cortex of the distal radius provides difficulties in discerning screw penetration on standard radiographs. The skyline and carpal shoot-through views are additional views to improve dorsal cortex visibility. We report on the sensitivity and specificity of determining screw protrusion with these views. METHODS: Seven fresh frozen cadavers were instrumented with a distal radius volar locking plate...
November 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29091020/do-clinical-and-radiological-assessments-contribute-to-the-understanding-of-biomaterials-results-from-a-prospective-randomized-sinus-augmentation-split-mouth-trial
#8
Jonas Lorenz, Tadas Korzinskas, Poju Chia, Sarah Al Maawi, Katrin Eichler, Robert Sader, Shahram Ghanaati
The present prospective randomized split-mouth trial reports on the 3-year clinical and radiological follow-up investigation of implants placed 7 months after sinus augmentation with two different bone substitute materials. Aim of the study was to complete the histologic observation of the cellular reactions by analysis of the implants and the volumetric changes of the augmented bone substitute materials. A sinus augmentation split-mouth trial was performed in 14 patients with the synthetic bone substitute material Nanobone® (NB) and the xenogeneic Bio-Oss® (BO)...
November 1, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29090970/ten-year-cbct-observation-of-the-buccal-bony-wall-of-an-immediately-placed-implant-at-the-anterior-maxilla-a-case-report
#9
Junho Jung, Kwantae Noh, Bilal Al-Nawas, Yong-Dae Kwon
Since the introduction of immediate implant placement, the buccal bony wall has been a major consideration for success, due to its correlation with soft tissue contour and color. This report presents the stability of the buccal wall thickness of an immediately placed implant at the anterior maxilla along 10-years. Although the width of the buccal wall had a decrease at post-op 2 years' follow-up, it remained stable afterwards, according to cone beam computed tomography (CBCT) scans. Hence, this report suggests that ensuring adequate bony wall thickness with bone augmentation and fixture position may promise the longevity of the buccal bony wall and surrounding soft tissue in immediate implant placement...
November 1, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29082127/autonomous-planning-and-control-of-soft-untethered-grippers-in-unstructured-environments
#10
Federico Ongaro, Stefano Scheggi, ChangKyu Yoon, Frank van den Brink, Seung Hyun Oh, David H Gracias, Sarthak Misra
The use of small, maneuverable, untethered and reconfigurable robots could provide numerous advantages in various micromanipulation tasks. Examples include microassembly, pick-and-place of fragile micro-objects for lab-on-a-chip applications, assisted hatching for in-vitro fertilization and minimally invasive surgery. This study assesses the potential of soft untethered magnetic grippers as alternatives or complements to conventional tethered or rigid micromanipulators. We demonstrate closed-loop control of untethered grippers and automated pick-and-place of biological material on porcine tissue in an unstructured environment...
2017: J Microbio Robot
https://www.readbyqxmd.com/read/29073551/medial-opening-wedge-high-tibial-osteotomy-in-patients-with-posttraumatic-medial-tibial-plateau-bone-defect-a-case-report
#11
Yoon Young Choi, Seung Joon Rhee
INTRODUCTION: Traumatic uncontained bone defect in the knee joint is one of the most serious knee injuries. As the knee joint is the main weight-bearing joint of the body, the problem of weight loading should be addressed while restoring the bone defect. However, no consensus exists regarding the treatment of this injury. PRESENTATION OF CASE: Two patients in separate cases initially sustained traumatic uncontained proximal tibial bone defects secondary to passenger traffic accidents...
October 18, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29073362/effectiveness-of-contour-augmentation-with-guided-bone-regeneration-10-year-results
#12
V Chappuis, L Rahman, R Buser, S F M Janner, U C Belser, D Buser
In aesthetic sites, the integrity of the facial bone wall dimension in the anterior maxilla is jeopardized by physiologic and structural changes postextraction. An effective regenerative protocol is key to reestablish and maintain the hard and soft tissue dimensions over time. The present prospective case series study examined the effectiveness of early implant placement with simultaneous contour augmentation through guided bone regeneration with a 2-layer composite graft in postextraction single-tooth sites over an observation period of 10 y among 20 patients...
October 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29068971/alterations-in-nasal-sensibility-following-calcium-hydroxyapatite-dorsal-augmentation
#13
Sami Alharethy
BACKGROUND: There are a many types of filler products that surgeons used for soft tissue augmentation. Soft Tissue Fillers, also known as injectable grafts, is a medical device implants. One of the materials used in soft tissue fillers is calcium hydroxylapatite (CaHA) that is commonly used for treating nasal deformities and nasal reshaping too. Calcium hydroxylapatite is a kind of mineral that can be found in human teeth and bones. It is considered long-lasting but nonpermanent filler and is biocompatible with human tissue...
October 24, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29068969/positive-effect-of-incubated-adipose-derived-mesenchymal-stem-cells-on-microfat-graft-survival
#14
Jong Woo Choi, Sung-Chan Kim, Eun-Jung Park, Ju-A Lee, Woo Shik Jeong
Autologous fat grafting is commonly used for soft tissue augmentation, but its unpredictably high resorption rate remains a major limitation. Although adipose-derived mesenchymal stem cells (ASCs) are an attractive candidate for enhancing graft retention, their poor posttransplantation viability limits their application. The authors aimed to evaluate the effect of incubated ASCs on microfat graft survival in an immunocompromised mouse model. Lipoaspirates for microfat injection were collected from the wasted lower abdominal adipose tissues of 5 patients who had undergone breast reconstructive surgery with an abdominal flap...
October 24, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29063145/-humeral-and-glenoid-bone-loss-in-shoulder-arthroplasty-classification-and-treatment-principles
#15
REVIEW
F Gohlke, B Werner
TECHNIQUE: The treatment of bone defects in primary shoulder arthroplasty has evolved due to more detailed diagnostic tools, 3D planning and expanded indications for reverse shoulder arthroplasty. Glenoid bone defects combined with chronic posterior subluxation of the humeral head are gradually being treated by glenoid reconstruction and reverse implants even if the rotator cuff is still intact. The treatment of advanced bone loss due to glenoid loosening has been facilitated by bone augmentation using a cementless fixation as proposed by Norris...
October 23, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/29053516/fat-graft-survival-after-recipient-site-pretreatment-with-fractional-carbon-dioxide-laser
#16
Sung-Eun Kim, Jun Ho Lee, Tae Gon Kim, Yong-Ha Kim, Kyu Jin Chung
BACKGROUND: Fat grafting is a commonly performed procedure not only for augmenting the soft tissue but also for regeneration in esthetic and reconstructive plastic surgery.However, unpredictable fat survival rate because of high resorption rate is remained as the main problem. The purpose of this study was to investigate the effect of pretreatment of the recipient site to the fat survival using fractional carbon dioxide (CO2) laser. METHODS: The rats were divided to 2 groups...
December 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29039637/peri-implant-soft-tissue-augmentation-in-a-mild-smoker-a-surgical-prosthetic-approach-using-a-subepithelial-ct-graft-with-coronal-anchoring-sutures-and-a-zirconia-abutment
#17
Neel Bhatavadekar, Bhakti Tunkiwala, Aliasger Tunkiwala
This report presents the use of a CT graft to augment the periimplant soft tissue at time of abutment placement in a smoker using coronal anchoring sutures around a zirconia abutment. Soft tissue augmentation at the time of abutment connection, avoiding abutment removal after CT grafting, use of a zirconia abutment and placement of coronal anchoring sutures might be the recommended approach when dealing with such esthetic challenges.
November 2016: Journal of the California Dental Association
https://www.readbyqxmd.com/read/29030619/unwavering-pathobiology-of-volumetric-muscle-loss-injury
#18
Sarah M Greising, Jessica C Rivera, Stephen M Goldman, Alain Watts, Carlos A Aguilar, Benjamin T Corona
Volumetric muscle loss (VML) resulting from extremity trauma presents chronic and persistent functional deficits which ultimately manifest disability. Acellular biological scaffolds, or decellularized extracellular matrices (ECMs), embody an ideal treatment platform due to their current clinical use for soft tissue repair, off-the-shelf availability, and zero autogenous donor tissue burden. ECMs have been reported to promote functional skeletal muscle tissue remodeling in small and large animal models of VML injury, and this conclusion was reached in a recent clinical trial that enrolled 13 patients...
October 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28975415/contour-changes-after-guided-bone-regeneration-of-large-non-contained-mandibular-buccal-bone-defects-using-deproteinized-bovine-bone-mineral-and-a-porcine-derived-collagen-membrane-an-experimental-in-vivo-investigation
#19
I Sanz-Martin, L Ferrantino, F Vignoletti, J Nuñez, N Baldini, M Duvina, J Alcaraz, M Sanz
OBJECTIVE: The objective of this study was to evaluate soft tissue contour changes after three different regenerative therapies in chronic ridge defects. MATERIAL AND METHODS: Buccal bone defects were created in the mandible of nine beagle dogs. Augmentation procedures were performed 3 months later using a bone replacement graft (BRG), resorbable collagen membrane (MBG), or a combination of both procedures (CBG). Silicone impressions were taken before tooth extraction (T1), before the augmentation procedure (T2), and 3 months after the regenerative surgeries (T3)...
October 3, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28967331/cone-beam-computed-tomography-and-interdisciplinary-dentofacial-therapy-an-american-academy-of-periodontology-best-evidence-review-focusing-on-risk-assessment-of-the-dentoalveolar-bone-changes-influenced-by-tooth-movement
#20
George A Mandelaris, Rodrigo Neiva, Leandro Chambrone
BACKGROUND: The aim of this systematic review is to evaluate whether cone-beam computed tomography (CBCT) imaging can be used to assess dentoalveolar anatomy critical to the periodontist when determining risk assessment for patients undergoing orthodontic therapy using fixed or removable appliances. METHODS: Both observational and interventional trials reporting on the use of CBCT imaging assessing the impact of orthodontic/dentofacial orthopedic treatment on periodontal tissues (i...
October 2017: Journal of Periodontology
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