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https://www.readbyqxmd.com/read/28239608/elimination-of-dog-mediated-human-rabies-deaths-by-2030-needs-assessment-and-alternatives-for-progress-based-on-dog-vaccination
#1
Ryan M Wallace, Eduardo A Undurraga, Jesse D Blanton, Julie Cleaton, Richard Franka
BACKGROUND: Rabies imposes a substantial burden to about half of the world population. The World Health Organization (WHO), World Organization for Animal Health, and the Food and Agriculture Organization have set the goal of eliminating dog-mediated human rabies deaths by 2030. This could be achieved largely by massive administration of post-exposure prophylaxis-in perpetuity-, through elimination of dog rabies, or combining both. Here, we focused on the resources needed for the elimination of dog rabies virus by 2030...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28239342/informative-cues-facilitate-saccadic-localization-in-blindsight-monkeys
#2
Masatoshi Yoshida, Ziad M Hafed, Tadashi Isa
Patients with damage to the primary visual cortex (V1) demonstrate residual visual performance during laboratory tasks despite denying having a conscious percept. The mechanisms behind such performance, often called blindsight, are not fully understood, but the use of surgically-induced unilateral V1 lesions in macaque monkeys provides a useful animal model for exploring such mechanisms. For example, V1-lesioned monkeys localize stimuli in a forced-choice condition while at the same time failing to report awareness of identical stimuli in a yes-no detection condition, similar to human patients...
2017: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/28239234/harnessing-demographic-differences-in-organizations-what-moderates-the-effects-of-workplace-diversity
#3
Yves R F Guillaume, Jeremy F Dawson, Lilian Otaye-Ebede, Stephen A Woods, Michael A West
To account for the double-edged nature of demographic workplace diversity (i.e,. relational demography, work group diversity, and organizational diversity) effects on social integration, performance, and well-being-related variables, research has moved away from simple main effect approaches and started examining variables that moderate these effects. While there is no shortage of primary studies of the conditions under which diversity leads to positive or negative outcomes, it remains unclear which contingency factors make it work...
February 2017: Journal of Organizational Behavior
https://www.readbyqxmd.com/read/28238987/identifying-factors-for-worker-motivation-in-zambia-s-rural-health-facilities
#4
Samuel S Cross, Dr Marianne Baernholdt
BACKGROUND: Within Zambia there is a shortage of health workers in rural areas. This study aims to identify motivating factors for retaining rural health workers. METHODS: Sixty rural health workers completed surveys and 46 were interviewed. They rated the importance of six motivating factors and discussed these and other factors in interviews. An interview was conducted with a Government Human Resources Manager (HR Manager) to elicit contextual information. RESULTS: All six factors were identified as being very important motivators, as were two additional factors...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28238798/unambiguous-high-resolution-genotyping-of-human-leukocyte-antigens
#5
Robert A Bradshaw, Paul P J Dunn
We have developed a high resolution sequencing based typing method for genotyping Human Leukocyte Antigens (HLA) over a period of twenty years. The methods are based upon the separation of HLA alleles per locus at the initial amplification to simplify the analysis post-sequencing. The increasing discovery of polymorphism in HLA, manifested in new alleles, has necessitated the continuing development of this method. Here we present methods for the high resolution Sequence Based Typing of HLA-A, B, C (class I) and HLA-DQB1 and DRB1 (class II)...
February 23, 2017: Journal of Immunological Methods
https://www.readbyqxmd.com/read/28238431/assessing-seawater-intrusion-in-an-arid-coastal-aquifer-under-high-anthropogenic-influence-using-major-constituents-sr-and-b-isotopes-in-groundwater
#6
J Mahlknecht, D Merchán, M Rosner, A Meixner, R Ledesma-Ruiz
The La Paz aquifer system (Baja California Sur, Mexico) is under severe anthropogenic pressure because of high groundwater abstraction for urban supply (city of La Paz, around 222,000 inhabitants) and irrigated agriculture (1900ha). In consequence, seawater has infiltrated the aquifer, forcing the abandonment of wells with increased salinity. The objective of this study was to assess seawater intrusion, understand the hydrogeochemical processes involved and estimate the contribution of seawater in the wells tested...
February 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28238224/a-comparative-toxidrome-analysis-of-human-organophosphate-and-nerve-agent-poisonings-using-social-media
#7
D S Reddy, E Colman
Here we utilized social media to compare the toxidrome of three lethal chemical exposures worldwide. YouTube videos were the main source from which the data were collected, but published reports and news were also utilized to fill in some gaps. All videos were organized in a database detailing symptoms and severity of each victim, along with demographics such as approximate age and gender. Each symptom was rated as mild, moderate, or severe and corresponding pie graphs for each incident were compared. The videos displayed symptoms ranging from mild to severe cholinergic toxicity and life-threatening convulsions...
February 26, 2017: Clinical and Translational Science
https://www.readbyqxmd.com/read/28236688/interventions-and-working-relationships-of-voluntary-organisations-for-diabetes-self-management-a-cross-national-study
#8
Mari Carmen Portillo, Anne Kennedy, Elka Todorova, Elena Regaira, Michel Wensing, Christina Foss, Christos Lionis, Ivaylo Vassilev, Valentin Goev, Anne Rogers
BACKGROUND: Diabetes has become a challenging health priority globally. Given the tensions of financially burdened health systems in Europe the mobilisation of community resources like voluntary organisations and community groups is seen as a health policy strategy to sustain the management of long-term conditions like diabetes. However, little is known about how this is happening in practice in Europe. OBJECTIVES: To explore diabetes self-management interventions undertaken or promoted by voluntary organisations and community groups in Europe; and describe the types of working relationships between these organisations, European health systems and users when implementing diabetes self-management programmes in different areas...
February 3, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28236149/hydrochemical-characterization-and-pollution-assessment-of-groundwater-in-jammu-siwaliks-india
#9
Shakil A Romshoo, Reyaz Ahmad Dar, Khalid Omar Murtaza, Irfan Rashid, Farooq A Dar
Physico-chemical groundwater (GW) parameters were evaluated to understand the hydrogeochemical processes in the Siwalik plains of Jammu and Kashmir, India. During the 2012-2013 post-monsoon (POM) and pre-monsoon (PRM) seasons, GW samples (n = 207) from deep bore wells and shallow open wells were chemically analysed. Cations (Ca(2+), Mg(2+), Na(+), K(+) and Fe(2+)) and anions (HCO3(-), Cl(-), SO4(2-) and F(-)) showed a wide spatio-temporal variation. Results suggest that weathering and dissolution of carbonates and silicate rocks is the main source of water mineralization...
March 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28235969/how-do-organisational-characteristics-influence-teamwork-and-service-delivery-in-lung-cancer-diagnostic-assessment-programmes-a-mixed-methods-study
#10
Gladys N Honein-AbouHaidar, Terri Stuart-McEwan, Tom Waddell, Alexandra Salvarrey, Jennifer Smylie, Mark J Dobrow, Melissa C Brouwers, Anna R Gagliardi
OBJECTIVES: Diagnostic assessment programmes (DAPs) can reduce wait times for cancer diagnosis, but optimal DAP design is unknown. This study explored how organisational characteristics influenced multidisciplinary teamwork and diagnostic service delivery in lung cancer DAPs. DESIGN: A mixed-methods approach integrated data from descriptive qualitative interviews and medical record abstraction at 4 lung cancer DAPs. Findings were analysed with the Integrated Team Effectiveness Model...
February 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28235829/a-dense-brown-trout-salmo-trutta-linkage-map-reveals-recent-chromosomal-rearrangements-in-the-salmo-genus-and-the-impact-of-selection-on-linked-neutral-diversity
#11
Maeva Leitwein, Bruno Guinand, Juliette Pouzadoux, Erick Desmarais, Patrick Berrebi, Pierre-Alexandre Gagnaire
High-density linkage maps are valuable tools for conservation and eco-evolutionary issues. In salmonids, a complex rediploidization process consecutive to an ancient whole genome duplication event makes linkage maps of prime importance for investigating the evolutionary history of chromosome rearrangements. Here, we developed a high-density consensus linkage map for the brown trout (Salmo trutta), a socio-economically important species heavily impacted by human activities. A total of 3,977 ddRAD markers were mapped and ordered in 40 linkage groups using sex- and lineage-averaged recombination distances obtained from two family crosses...
February 24, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28235663/the-perceptual-and-phenomenal-capacity-of-mental-imagery
#12
Rebecca Keogh, Joel Pearson
Despite the brain's immense processing power, it has finite resources. Where do these resource limits come from? Little research has examined possible low-level sensory contributions to these limitations. Mental imagery is a fundamental part of human cognition that bridges cognition with sensory representations. Hence, imagery serves as a good candidate sensory process for probing how low capacity limitations might extend down the processing hierarchy. Here we introduce a novel technique to measure the sensory capacity of mental imagery, while removing the need for memory and any direct subjective reports...
February 21, 2017: Cognition
https://www.readbyqxmd.com/read/28231077/association-of-genetic-variation-in-the-tachykinin-receptor-3-locus-with-hot-flashes-and-night-sweats-in-the-women-s-health-initiative-study
#13
Carolyn J Crandall, JoAnn E Manson, Chancellor Hohensee, Steve Horvath, Jean Wactawski-Wende, Erin S LeBlanc, Mara Z Vitolins, Rami Nassir, Janet S Sinsheimer
OBJECTIVE: Vasomotor symptoms (VMS, ie, hot flashes or night sweats) are reported by many, but not all, women. The extent to which VMS are genetically determined is unknown. We evaluated the relationship of genetic variation and VMS. METHODS: In this observational study, we accessed data from three genome-wide association studies (GWAS) (SNP Health Association Resource cohort [SHARe], WHI Memory Study cohort [WHIMS+], and Genome-Wide Association Studies of Treatment Response in Randomized Clinical Trials [GARNET] studies, total n = 17,695) of European American, African American, and Hispanic American postmenopausal women aged 50 to 79 years at baseline in the Women's Health Initiative Study...
March 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28230162/n-acetylated-proline-glycine-proline-accelerates-cutaneous-wound-healing-and-neovascularization-by-human-endothelial-progenitor-cells
#14
Yang Woo Kwon, Soon Chul Heo, Tae Wook Lee, Gyu Tae Park, Jung Won Yoon, Il Ho Jang, Seung-Chul Kim, Hyun-Chang Ko, Youngjae Ryu, Hyeona Kang, Chang Man Ha, Sang Chul Lee, Jae Ho Kim
Human endothelial progenitor cells (hEPCs) are promising therapeutic resources for wound repair through stimulating neovascularization. However, the hEPCs-based cell therapy has been hampered by poor engraftment of transplanted cells. In this study, we explored the effects of N-acetylated Proline-Glycine-Proline (Ac-PGP), a degradation product of collagen, on hEPC-mediated cutaneous wound healing and neovascularization. Treatment of hEPCs with Ac-PGP increased migration, proliferation, and tube-forming activity of hEPCs in vitro...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28229194/screening-level-assessment-of-metal-concentrations-in-streambed-sediments-and-floodplain-soils-within-the-grand-lake-watershed-in-northeastern-oklahoma-usa
#15
Ean M Garvin, Cas F Bridge, Meredith S Garvin
Metal releases have been received by the Grand Lake watershed from the Tri-State Mining District (TSMD) since the mid 1800s. To address data gaps in metal distributions in the Oklahoma portion of the watershed, streambed sediment and floodplain soil was sampled on various streams. The <63-µm fraction was analyzed for Cd, Pb, and Zn concentrations by portable X-ray fluorescence spectroscopy and inductively coupled plasma-mass spectrometry. Mean metal concentration results at reference transects indicated that background sediment/soil concentrations for Cd, Pb, and Zn within the watershed were 0...
February 22, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28228450/academic-outcomes-in-children-with-congenital-heart-defects-a-population-based-cohort-study
#16
Matthew E Oster, Stephanie Watkins, Kevin D Hill, Jessica H Knight, Robert E Meyer
BACKGROUND: Most studies evaluating neurocognitive outcomes in children with congenital heart defects (CHD) have focused on high-risk patients or used specialized, resource-intensive testing. To determine the association of CHD with academic outcomes and compare outcomes according to the severity of CHD, we linked state educational records with a birth defects registry and birth certificates. METHODS AND RESULTS: We performed a retrospective cohort study using data from the North Carolina Birth Defects Monitoring Program, North Carolina Department of Public Instruction, and North Carolina Department of Health and Human Services vital records...
February 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28227534/quantifying-the-human-finger-reachable-space
#17
Trieu H Pham, Pubudu N Pathirana, Trieu H Pham, Pubudu N Pathirana, Trieu H Pham, Pubudu N Pathirana
Describing the flexibility of the hand using the reachable space concept has drawn the attention of many researchers in recent years. Existing approaches involving numerical techniques to obtain the reachable space are generally computationally expensive. In this study, we propose a resource-friendly approach to determine and quantify the bidimensional reachable space of the finger. The fundamental idea of the approach connects to a set of arc formulae for the boundary of the reachable space. These formulae of the boundary result a unique description to calculate the area of the reachable space using Green's theorem...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226017/-evaluation-of-psychosocial-care-centers-structure-in-the-region-of-m%C3%A3-dio-paraopeba-minas-gerais-brazil
#18
Sarah Nascimento Silva, Marina Guimarães Lima
OBJECTIVE: to evaluate the physical facilities, human resources and activities developed in the Psychosocial Care Centers (CAPS) in the region of Médio Paraopeba, Minas Gerais, Brazil, in 2014. METHODS: this is an evaluation study of the dimensions of structure and processes proposed by Donabedian, based on recommendations of the Ministry of Health and current laws; semi-structured forms were used to interview health managers; direct observation of mental health services was performed...
January 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28226016/-geographical-and-organizational-aspects-of-primary-health-care-services-in-detecting-tuberculosis-cases-in-pelotas-rio-grande-do-sul-brazil-2012
#19
Simone Pieren Dos Reis, Jenifer Harter, Lílian Moura de Lima, Dagoberta Alves Vieira, Pedro Fredemir Palha, Roxana Isabel Cardozo Gonzales
OBJECTIVE: to evaluate the geographical and organizational aspects of primary health care services in detecting tuberculosis cases in Pelotas-RS, Brazil. METHODS: this was a descriptive evaluation study involving 276 health professionals in 2012; data were collected using a structured questionnaire covering geographical and organizational aspects which received a score using a Likert scale of 1 to 5. RESULTS: average use of motorized transport by symptomatic respiratory patients having a cough for more than three weeks to get to a healthcare service was considered regular by respondents; although there was satisfactory availability of health professionals, human resource turnover and time-keeping were considered unsatisfactory; average time of more than 60 minutes waiting to see the doctor and average time spent with the doctor were considered regular...
January 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28224422/satisfaction-of-village-doctors-with-the-township-and-village-health-services-integration-policy-in-the-western-minority-inhabited-areas-of-china
#20
Da Feng, Liang Zhang, Yuan-Xi Xiang, Dong-Lan Zhang, Ruo-Xi Wang, Shang-Feng Tang, Hang Fu, Bo-Yang Li
Township and Village Health Services Integration Management (TVHSIM) is an essential form of China's two-tiered health service integration plan at the township and village level. Its main purpose, also one of the target goals in China's new healthcare reform, is to gradually integrate rural health services and appropriately allocate rural health resources. This study aims to assess the village doctors' satisfaction with the TVHSIM and provide scientific base to further improve TVHSIM. A cross-sectional study was carried out in which 162 village doctors from Qinghai, Inner Mongolia and Xinjiang in western China were interviewed...
February 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
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