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A Palmieri, A Avantaggiato, F Cura, M Casale, M A Lopez, F Bressi, L Scapoli
Bio-revitalization is a therapy commonly used in aesthetic medicine to improve skin quality by di¬rectly integrating hyaluronic acid alone or added to other molecules (i.e. vitamins) through intradermal injections. These injections are not aimed to fill roughness but to achieve extracellular matrix optimi¬zation. The injective medical devices used in aesthetic medicine differ for hyaluronic acid content and for the presence of additional molecules that characterize the formulation of a particular company...
December 27, 2017: Journal of Biological Regulators and Homeostatic Agents
Antonietta Stellavato, Luisana Corsuto, Antonella D'Agostino, Annalisa La Gatta, Paola Diana, Patrizia Bernini, Mario De Rosa, Chiara Schiraldi
Hyaluronic Acid (HA)-based dermal formulations have rapidly gained a large consensus in aesthetic medicine and dermatology. HA, highly expressed in the Extracellular Matrix (ECM), acts as an activator of biological cascades, stimulating cell migration and proliferation, and operating as a regulator of the skin immune surveillance, through specific interactions with its receptors. HA may be used in topical formulations, as dermal inducer, for wound healing. Moreover, intradermal HA formulations (injectable HA) provide an attractive tool to counteract skin aging (e...
2016: PloS One
Pierre-Antoine Deglesne, Rodrigo Arroyo, Evgeniya Ranneva, Philippe Deprez
Mesotherapy/biorevitalization with hyaluronic acid (HA) is a treatment approach currently used for skin rejuvenation. Various products with a wide range of polycomponent formulations are available on the market. Most of these formulations contain noncross-linked HA in combination with a biorevitalization cocktail, formed by various amounts of vitamins, minerals, amino acids, nucleotides, coenzymes, and antioxidants. Although ingredients are very similar among the different products, in vitro and clinical effects may vary substantially...
2016: Clinical, Cosmetic and Investigational Dermatology
Maria Teresa Sanz, Celia Campos, Massimo Milani, Monica Foyaca, Amandine Lamy, Karine Kurdian, Carles Trullas
BACKGROUND: Epithelial regeneration in skin is achieved by the constant turnover and differentiation of keratinocytes. Epidermal and dermal stem cells compartments are fundamental for the continuous renewal of the skin. Adult stem cells are the unique source for skin tissue renewal. Plants have stem cells and plant derived stem cell extracts are now used in topical products for their potential anti-ageing and anti-wrinkle effects. A new dermocosmetic product containing apple stem cell extract, urea, creatine and palmitoyl tripeptide-38 (Ureadin Fusion Serum Lift Antiarrugas, ISDIN S...
March 2016: Journal of Cosmetic Dermatology
Adele Sparavigna, Beatrice Tenconi, Ileana De Ponti
BACKGROUND: Age-related changes in the dermis can be considered the result of intrinsic factors and the consequence of environmental damage, mainly due to ultraviolet (UV) radiation from the sun (responsible for skin photoaging). The great versatility of the mesotherapy "biorevitalization" lies in the synergy between different biological effects of the active injected substances, which treats the skin in a more complete way. Several studies about biorevitalization efficacy showed good results...
2015: Clinical, Cosmetic and Investigational Dermatology
Antonella Savoia, Fulvio Vannini, Alfonso Baldi
INTRODUCTION: This study describes a pivotal clinical trial of a new minimally invasive cosmetic procedure for facial rejuvenation and for the treatment of scars and wrinkles. METHODS: The procedure consisted of a combination of techniques such as fillers, biorevitalization, peeling, and intradermal radiofrequency, emitted from a new device denominated by Spherofill Medical Plus (SMP; Spherofill MD, PromoItalia Group S.p.A., Pozzuoli, Italy), for treating cutaneous regeneration, depressions, and striae...
September 2011: Dermatology and Therapy
Moetaz El-Domyati, Tarek S El-Ammawi, Osama Moawad, Hasan El-Fakahany, Walid Medhat, Mỹ G Mahoney, Jouni Uitto
BACKGROUND: Mesotherapy, commonly known as "biorejuvenation" or "biorevitalization", is a technique used to rejuvenate the skin by means of a transdermal injection of a multivitamin solution and natural plant extracts that are thought to improve the signs of skin aging. OBJECTIVES: This prospective study aimed to evaluate the clinical effect of mesotherapy applied to periorbital wrinkles and to quantitatively evaluate histological changes in the skin occurring in response to the same treatment...
August 2012: International Journal of Dermatology
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