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Pediatric skin protection

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https://www.readbyqxmd.com/read/29787623/pediatric-mastocytosis-long-term-follow-up-of-53-patients-with-whole-sequencing-of-kit-a-prospective-study
#1
C Méni, S Georgin-Lavialle, L Le Saché de Peufeilhoux, J P Jais, S Hadj Rabia, J Bruneau, S Fraitag, K Hanssens, P Dubreuil, O Hermine, C Bodemer
OBJECTIVE: To describe the clinical evolution of a well characterized pediatric mastocytosis (PM) cohort. To analyze the relationship between KIT mutation and the clinical course. DESIGN: Prospective cohort study. Diagnosis was confirmed by identification of KIT mutation on lesional skin biopsy. Mastocytosis subtype, Mast Cell Mediator-Related Symptoms (MC MRS), clinical course were recorded. SETTING: National Clinical Reference Center for Mastocytosis (CEREMAST)...
May 22, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29762868/candidemia-in-children-epidemiology-prevention-and-management
#2
REVIEW
Elpis Mantadakis, Zoe Dorothea Pana, Theoklis Zaoutis
Candidemia is the leading cause of invasive fungal infections in hospitalized children. The highest rates of candidemia have been recorded in neonates and infants <1 year of age. Candidemia is more frequent in neonates and young infants than in adults, and is associated with better clinical outcomes, but higher inpatient costs. Over the last 10 years, a declining trend has been noted in the incidence of pediatric candidemia in the US and elsewhere due to the hospital-wide implementation of central-line insertion and maintenance bundles that emphasize full sterile barrier precautions, chlorhexidine skin preparation during line insertion, meticulous site and tubing care, and daily discussion of catheter necessity...
May 15, 2018: Mycoses
https://www.readbyqxmd.com/read/29753234/effect-of-short-term-hazelnut-consumption-on-dna-damage-and-oxidized-ldl-in-children-and-adolescents-with-primary-hyperlipidemia-a-randomized-controlled-trial
#3
Federica Guaraldi, Valeria Deon, Cristian Del Bo', Stefano Vendrame, Marisa Porrini, Patrizia Riso, Ornella Guardamagna
Children with primary hyperlipidemia are prone to develop premature atherosclerosis, possibly associated with increased oxidative stress. Nutritional therapy is the primary strategy in the treatment of hyperlipidemia and associated conditions. Dietary interventions with bioactive-rich foods, such as nuts, may contribute to the modulation of both lipid profile and the oxidative/antioxidant status. Our study aimed to assess the impact of a dietary intervention with hazelnuts on selected oxidative stress markers in children and adolescents with primary hyperlipidemia...
March 20, 2018: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29673096/impact-of-graft-thickness-reduction-of-left-lateral-segment-on-outcomes-following-pediatric-living-donor-liver-transplantation
#4
Toshihiro Kitajima, Seisuke Sakamoto, Kengo Sasaki, Soichi Narumoto, Kourosh Kazemi, Yoshihiro Hirata, Akinari Fukuda, Rumi Imai, Osamu Miyazaki, Rie Irie, Satoshi Teramukai, Shinji Uemoto, Mureo Kasahara
Reducing graft thickness is essential to prevent large-for-size graft problems in pediatric living donor liver transplantation (LDLT). However, long-term outcomes of LDLT using reduced-thickness left lateral segment (LLS) grafts are unclear. In 89 patients who underwent LDLT using reduced LLS grafts between 2005 and 2017, short-term and long-term outcomes were compared between a non-anatomically reduced LLS (NAR-LLS) graft group and a reduced-thickness LLS graft group. Estimated blood loss was lower and abdominal skin closure was less needed in the recipient operation in the reduced-thickness LLS graft group...
April 19, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29658451/-clinical-and-genetic-analysis-of-a-pediatric-patient-with-sodium-taurocholate-cotransporting-polypeptide-deficiency
#5
Hua Li, Jian-Wu Qiu, Gui-Zhi Lin, Mei Deng, Wei-Xia Lin, Ying Cheng, Yuan-Zong Song
Sodium taurocholate cotransporting polypeptide (NTCP) deficiency is an inborn error of bile acid metabolism caused by mutations of SLC10A1 gene. This paper reports the clinical and genetic features of a patient with this disease. A 3.3-month-old male infant was referred to the hospital with the complaint of jaundiced skin and sclera over 3 months. Physical examination revealed moderate jaundice of the skin and sclera. The liver was palpable 3.5 cm below the right subcostal margin with a medium texture. Serum biochemistry analysis revealed markedly elevated bilirubin (predominantly direct bilirubin) and total bile acids (TBA), as well as decreased 25-OH-VitD level...
April 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29558557/behavioral-counseling-for-skin-cancer-prevention-evidence-report-and-systematic-review-for-the-us-preventive-services-task-force
#6
REVIEW
Nora B Henrikson, Caitlin C Morrison, Paula R Blasi, Matt Nguyen, Kendall C Shibuya, Carrie D Patnode
Importance: Exposure to UV radiation, especially in childhood, increases skin cancer risk. Objective: To systematically review the evidence on the benefits and harms of behavioral counseling for skin cancer prevention to inform the US Preventive Services Task Force (USPSTF). Data Sources: Cochrane Central Register of Controlled Trials, MEDLINE, and PubMed were searched for studies published from January 2009 to March 31, 2016, for skin cancer prevention and from August 2005 to March 31, 2016, for skin self-examination...
March 20, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29532579/editorial-comments-on-this-issue-of-the-journal
#7
EDITORIAL
Philippe Eigenmann
No abstract text is available yet for this article.
May 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29468720/family-management-of-childhood-atopic-dermatitis
#8
Hae Kyoung Son, Dong Hee Kim, Hyejung Lee, Heejung Kim, Kyoungmee Chung, Hee-Soon Kim
AIMS: To identify the variables that affect family management of childhood atopic dermatitis and establish a prediction model based on Bandura's self-efficacy theory. BACKGROUND: Atopic dermatitis is a chronic recurrent skin disease and common health problem in childhood. It is necessary to use an approach that includes parental factors when considering the effective management of childhood atopic dermatitis. DESIGN: A cross-sectional study design...
February 22, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29457372/clinical-characteristics-and-factors-associated-with-disability-and-impaired-quality-of-life-in-children-with-juvenile-systemic-sclerosis
#9
Brandi E Stevens, Kathryn S Torok, Suzanne C Li, Nicole Hershey, Megan Curran, Gloria C Higgins, Katharine F Moore, C Egla Rabinovich, Samuel Dodson, Anne M Stevens
OBJECTIVE: To investigate clinical manifestations of juvenile systemic sclerosis (jSSc), including disease characteristics and patient quality of life, through the multinational Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry. METHODS: Subjects with jSSc were prospectively enrolled between 2010 and 2013. Diagnosis of jSSc was determined by the enrolling pediatric rheumatologist, with disease onset required prior to age 18. Collected data included demographics, disease characteristics, medication exposure, and quality of life metrics...
February 18, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29397270/device-related-pressure-ulcers-pre-and-post-identification-and-intervention
#10
Pamela Clay, Casey Cruz, Keith Ayotte, Jeremy Jones, Susan B Fowler
PROBLEM: From 2014 to 2016, device related pressure injuries accounted for 62-81% of all hospital acquired pressure injuries. From January to June 2014, there were 5 BiPAP/CPAP pressure injuries noted, accounting for 3.579 injuries per 1000 ventilator days. In 2015, hospital data revealed that 26.5% of all hospital acquired pressure injuries occurred to prone surgical spine patients. METHODS: Collaborative teams including respiratory therapists and operating room staff were convened and crafted new strategies...
January 31, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29377413/assessment-of-the-general-quality-of-sunscreen-products-available-in-palestine-and-method-verification-of-the-sun-protection-factor-using-food-and-drug-administration-guidelines
#11
Abdel Naser Zaid, Nidal Jaradat, Saja Darwish, Sura Nairat, Rawan Shamlawi, Yasmeen Hamad, Fatema Hussein, Linda Issa
BACKGROUND: Sunlight exposure affects all skin types causing skin tanning, burns or even skin cancer. Sunscreens were invented to prevent these outcomes by scattering or absorbing the UV light. AIMS: This study aimed to verify the effectiveness of Mansur method in SPF measurement and to find out how much reliable the labeled sun protection factor (SPF) value for the products that are imported to Palestine knowing that they are considered as cosmetics and they don't undergo tests by the Ministry Of Health (MOH)...
January 29, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29373475/lessons-from-an-outbreak-of-varicella-infection-in-pediatric-hemato-oncology-patients
#12
Michal Manistarski, Dror Levin, Rina Dvir, Sivan Berger-Achituv, Hila Rosenfeld Keidar, Galia Grisaru-Soen, Yehuda Carmeli, Ronit Elhasid
BACKGROUND: Immunocompromized patients exposed to varicella may experience significant morbidity and a 7% mortality rate. Management and outcome of an outbreak of varicella infection among hospitalized pediatric hemato-oncology patients using the guidelines of the American Academy of Pediatrics Committee on Infectious Diseases is presented. PATIENTS AND METHODS: This retrospective study describes an outbreak of varicella infection between February 2011 and June 2011...
January 25, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29369414/molecular-sensitization-patterns-and-influence-of-molecular-diagnosis-in-immunotherapy-prescription-in-children-sensitized-to-both-grass-and-olive-pollen
#13
Ana Martínez-Cañavate Burgos, Javier Torres-Borrego, Ana Belén Molina Terán, Jose Luis Corzo, Blanca Esther Garcia, Ramón Rodríguez Pacheco, Carmen Moreno Aguilar, Ignacio Dávila
BACKGROUND: The overlapping grass and olive pollen seasons in Spain and the phenomenon of cross-reactivity can make it difficult to determine the true causative agent of seasonal allergic rhinitis when only skin prick tests with whole extracts are used. The aim of the GRAMOLE study was to determine sensitization patterns to the major grass and olive pollen allergens detected using specific recombinant IgE and to explore how this knowledge affected physicians' choice of allergen-specific immunotherapy...
January 25, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29360238/concentration-of-filaggrin-monomers-its-metabolites-and-corneocyte-surface-texture-in-individuals-with-a-history-of-atopic-dermatitis-and-controls
#14
K A Engebretsen, J Bandier, S Kezic, C Riethmüller, N H H Heegaard, B C Carlsen, A Linneberg, J D Johansen, J P Thyssen
BACKGROUND: Atopic dermatitis (AD) is characterized by skin barrier dysfunction. Notably, a high number of nano-scale protrusions on the surface of corneocytes, which can be expressed by the Dermal Texture Index (DTI), were recently associated with paediatric AD, loss-of-function mutations in filaggrin gene (FLG) and reduced levels of natural moisturizing factors (NMF). No study has so far examined the association between these parameters and monomeric filaggrin levels in adults. OBJECTIVE: To determine DTI, monomeric filaggrin and NMF in healthy controls and a group of patients with controlled dermatitis...
May 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29356106/pigmented-fungiform-lingual-papillae-dermoscopic-and-clinical-features
#15
REVIEW
M A Chessa, A Patrizi, A Sechi, A Virdi, M Leuzzi, I Neri
The tongue is covered by fungiform, filiform and circumvallate papillae. Fungiform papillae may be mainly pigmented in dark-skinned individuals. A single-centre study aimed to examine the clinical and dermoscopic features of pigmented fungiform papulae of the tongue (PFPT) in children, and a concise review of the literature has been performed. The clinical and anamnestic data of eight children affected by PFPT visited at the Pediatric Dermatology Unit of Bologna between 2010 and 2017, and a systemic review of all studies of PFPT published on PubMed up to 31 August 2017 has been collected and analysed...
January 22, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29241963/negative-pressure-wound-therapy-in-pediatric-surgery-how-and-when-to-use
#16
REVIEW
Lisieux Eyer de Jesus, Alana Bandeira Martins, Pablo Baptista Oliveira, Fernanda Gomes, Thais Leve, Samuel Dekermacher
INTRODUCTION: Negative pressure wound therapy (NPWT) has been widely adopted to treat laparostomy, abdominal compartment syndrome (ACS) and complicated wounds associated with tissue loss. The method presents specific aspects, advantages and indications in Pediatrics. Our aim is to review the evidence available about NPWT in children. METHODS: Active search for papers about NPWT in Pediatric patients. Papers referring to orthopedic problems, wound complications after Cardiac Surgery or burns were excluded...
April 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29222945/children-with-atopic-dermatitis-may-have-unacknowledged-contact-allergies-contributing-to-their-skin-symptoms
#17
A B Simonsen, J D Johansen, M Deleuran, C G Mortz, L Skov, M Sommerlund
BACKGROUND: Whether children with atopic dermatitis have an altered risk of contact allergy than children without atopic dermatitis is frequently debated and studies have been conflicting. Theoretically, the impaired skin barrier in atopic dermatitis (AD) facilitates the penetration of potential allergens and several authors have highlighted the risk of underestimating and overlooking contact allergy in children with atopic dermatitis. OBJECTIVE: To determine the prevalence of contact allergy in Danish children with atopic dermatitis and explore the problem of unacknowledged allergies maintaining or aggravating the skin symptoms...
March 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29171923/clinical-and-genetic-findings-in-children-with-central-nervous-system-arteriovenous-fistulas
#18
Guillaume Saliou, Mélanie Eyries, Marta Iacobucci, Jean-François Knebel, Marie-Christine Waill, Florence Coulet, Augustin Ozanne, Florent Soubrier
OBJECTIVE: To assess the spectrum of genetic anomalies in a cohort of children presenting at least one cerebral or spinal pial arteriovenous fistula (AVF), and to describe their clinical characteristics. METHODS: From 1988 to 2016, all consecutive patients with at least one cerebral or spinal pial AVF were screened for genetic disease. All patients aged <18 years were included. Symptoms associated with AVF were recorded: heart failure, neurological deficit/seizure, and hemorrhage...
December 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29148002/targeting-zero-catheter-related-bloodstream-infections-in-pediatric-intensive-care-unit-a-retrospective-matched-case-control-study
#19
Daniele G Biasucci, Mauro Pittiruti, Alessandra Taddei, Enzo Picconi, Alessandro Pizza, Davide Celentano, Marco Piastra, Giancarlo Scoppettuolo, Giorgio Conti
INTRODUCTION: The aim of this study was to evaluate the effectiveness and safety of a new three-component 'bundle' for insertion and management of centrally inserted central catheters (CICCs), designed to minimize catheter-related bloodstream infections (CRBSIs) in critically ill children. METHODS: Our 'bundle' has three components: insertion, management, and education. Insertion and management recommendations include: skin antisepsis with 2% chlorhexidine; maximal barrier precautions; ultrasound-guided venipuncture; tunneling of the catheter when a long indwelling time is expected; glue on the exit site; sutureless securement; use of transparent dressing; chlorhexidine sponge dressing on the 7th day; neutral displacement needle-free connectors...
March 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29127209/counseling-on-sun-protection-and-indoor-tanning
#20
Sophie J Balk, Elizabeth A Gottschlich, Dawn M Holman, Meg Watson
BACKGROUND: The US Preventive Services Task Force recommends clinical counseling for individuals ages 10 to 24 years to decrease skin cancer risk. METHODS: A national, random sample of US American Academy of Pediatrics members practicing primary care in 2002 (response rate 55%) and 2015 (response rate 43%). Surveys explored attitudes and experiences regarding sun protection counseling; indoor tanning questions were added in 2015. χ2 tests compared demographics and counseling responses across years, and multivariable logistic regression models examined counseling predictors...
December 2017: Pediatrics
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