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Pediatric skin protection

Philippe A Eigenmann
Skin diseases related to allergy are common in childhood and pediatric allergists are commonly faced with atopic eczema, treatment schemes for which include calcineurin inhibitors: commonly used topical drugs which control inflammatory skin flares. In the first review of this issue, Nakahira et al provide mechanistic insights, among others, into modulation of the immune response by tacrolimus (1). Prevention of atopic eczema is addressed by Wickens et al. This article is protected by copyright. All rights reserved...
March 13, 2018: Pediatric Allergy and Immunology
Hae Kyoung Son, Dong Hee Kim, Hyejung Lee, Heejung Kim, Kyoungmee Chung, Hee-Soon Kim
AIMS: To identify the variables that affect family management of childhood atopic dermatitis and establish a prediction model based on Bandura's self-efficacy theory. BACKGROUND: Atopic dermatitis is a chronic recurrent skin disease and common health problem in childhood. It is necessary to use an approach that includes parental factors when considering the effective management of childhood atopic dermatitis. DESIGN: A cross-sectional study design...
February 22, 2018: Journal of Advanced Nursing
Brandi E Stevens, Kathryn S Torok, Suzanne C Li, Nicole Hershey, Megan Curran, Gloria C Higgins, Katharine F Moore, C Egla Rabinovich, Samuel Dodson, Anne M Stevens
OBJECTIVE: To investigate clinical manifestations of juvenile systemic sclerosis (jSSc), including disease characteristics and patient quality of life, through the multinational Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry. METHODS: Subjects with jSSc were prospectively enrolled between 2010 and 2013. Diagnosis of jSSc was determined by the enrolling pediatric rheumatologist, with disease onset required prior to age 18. Collected data included demographics, disease characteristics, medication exposure, and quality of life metrics...
February 18, 2018: Arthritis Care & Research
Pamela Clay, Casey Cruz, Keith Ayotte, Jeremy Jones, Susan B Fowler
PROBLEM: From 2014 to 2016, device related pressure injuries accounted for 62-81% of all hospital acquired pressure injuries. From January to June 2014, there were 5 BiPAP/CPAP pressure injuries noted, accounting for 3.579 injuries per 1000 ventilator days. In 2015, hospital data revealed that 26.5% of all hospital acquired pressure injuries occurred to prone surgical spine patients. METHODS: Collaborative teams including respiratory therapists and operating room staff were convened and crafted new strategies...
January 31, 2018: Journal of Pediatric Nursing
Abdel Naser Zaid, Nidal Jaradat, Saja Darwish, Sura Nairat, Rawan Shamlawi, Yasmeen Hamad, Fatema Hussein, Linda Issa
BACKGROUND: Sunlight exposure affects all skin types causing skin tanning, burns or even skin cancer. Sunscreens were invented to prevent these outcomes by scattering or absorbing the UV light. AIMS: This study aimed to verify the effectiveness of Mansur method in SPF measurement and to find out how much reliable the labeled sun protection factor (SPF) value for the products that are imported to Palestine knowing that they are considered as cosmetics and they don't undergo tests by the Ministry Of Health (MOH)...
January 29, 2018: Journal of Cosmetic Dermatology
Michal Manistarski, Dror Levin, Rina Dvir, Sivan Berger-Achituv, Hila Rosenfeld Keidar, Galia Grisaru-Soen, Yehuda Carmeli, Ronit Elhasid
BACKGROUND: Immunocompromized patients exposed to varicella may experience significant morbidity and a 7% mortality rate. Management and outcome of an outbreak of varicella infection among hospitalized pediatric hemato-oncology patients using the guidelines of the American Academy of Pediatrics Committee on Infectious Diseases is presented. PATIENTS AND METHODS: This retrospective study describes an outbreak of varicella infection between February 2011 and June 2011...
January 25, 2018: Pediatric Infectious Disease Journal
Ana Martínez-Cañavate Burgos, Javier Torres-Borrego, Ana Belén Molina Terán, Jose Luis Corzo, Blanca Esther Garcia, Ramón Rodríguez Pacheco, Carmen Moreno Aguilar, Ignacio Dávila
BACKGROUND: The overlapping grass and olive pollen seasons in Spain and the phenomenon of cross-reactivity can make it difficult to determine the true causative agent of seasonal allergic rhinitis when only skin prick tests with whole extracts are used. The aim of the GRAMOLE study was to determine sensitization patterns to the major grass and olive pollen allergens detected using specific recombinant IgE and to explore how this knowledge affected physicians' choice of allergen-specific immunotherapy...
January 25, 2018: Pediatric Allergy and Immunology
Kristiane A Engebretsen, Josefine Bandier, Sanja Kezic, Christoph Riethmüller, Niels H H Heegaard, Berit C Carlsen, Allan Linneberg, Jeanne D Johansen, Jacob P Thyssen
BACKGROUND: Atopic dermatitis (AD) is characterized by skin barrier dysfunction. Notably, a high number of nano-scale protrusions on the surface of corneocytes, which can be expressed by the Dermal Texture Index (DTI), was recently associated with pediatric AD, loss-of-function mutations in filaggrin gene (FLG), and reduced levels of natural moisturizing factors (NMF). No study has so far examined the association between these parameters and monomeric filaggrin levels in adults. OBJECTIVE: To determine DTI, monomeric filaggrin and NMF in healthy controls and a group of patients with controlled dermatitis...
January 23, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
Marco Adriano Chessa, Annalisa Patrizi, Andrea Sechi, Annalucia Virdi, Miriam Leuzzi, Iria Neri
BACKGROUND: The tongue is covered by fungiform, filiform and circumvallate papillae. Fungiform papillae may be mainly pigmented in dark-skinned individuals. OBJECTIVE: A single-center study aimed to examine the clinical and dermoscopic features of pigmented fungiform papulae of the tongue (PFPT) in children, and a concise review of the literature has been performed. METHODS: The clinical and anamnestic data of 8 children affected by PFPT visited at the Pediatric Dermatology Unit of Bologna between 2010 and 2017, and a sistemic review of all studies of PFPT published on Pubmed up to August 31, 2017 have been collected and analyzed...
January 22, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
Lisieux Eyer de Jesus, Alana Bandeira Martins, Pablo Baptista Oliveira, Fernanda Gomes, Thais Leve, Samuel Dekermacher
INTRODUCTION: Negative pressure wound therapy (NPWT) has been widely adopted to treat laparostomy, abdominal compartment syndrome (ACS) and complicated wounds associated with tissue loss. The method presents specific aspects, advantages and indications in Pediatrics. Our aim is to review the evidence available about NPWT in children. METHODS: Active search for papers about NPWT in Pediatric patients. Papers referring to orthopedic problems, wound complications after Cardiac Surgery or burns were excluded...
November 21, 2017: Journal of Pediatric Surgery
A B Simonsen, J D Johansen, M Deleuran, C G Mortz, L Skov, M Sommerlund
BACKGROUND: Whether children with atopic dermatitis have an altered risk of contact allergy than children without atopic dermatitis is frequently debated and studies have been conflicting. Theoretically, the impaired skin barrier in atopic dermatitis (AD) facilitates the penetration of potential allergens and several authors have highlighted the risk of underestimating and overlooking contact allergy in children with atopic dermatitis. OBJECTIVE: To determine the prevalence of contact allergy in Danish children with atopic dermatitis and explore the problem of unacknowledged allergies maintaining or aggravating the skin symptoms...
December 9, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
Guillaume Saliou, Mélanie Eyries, Marta Iacobucci, Jean-François Knebel, Marie-Christine Waill, Florence Coulet, Augustin Ozanne, Florent Soubrier
OBJECTIVE: To assess the spectrum of genetic anomalies in a cohort of children presenting at least one cerebral or spinal pial arteriovenous fistula (AVF), and to describe their clinical characteristics. METHODS: From 1988 to 2016, all consecutive patients with at least one cerebral or spinal pial AVF were screened for genetic disease. All patients aged <18 years were included. Symptoms associated with AVF were recorded: heart failure, neurological deficit/seizure, and hemorrhage...
December 2017: Annals of Neurology
Daniele G Biasucci, Mauro Pittiruti, Alessandra Taddei, Enzo Picconi, Alessandro Pizza, Davide Celentano, Marco Piastra, Giancarlo Scoppettuolo, Giorgio Conti
INTRODUCTION: The aim of this study was to evaluate the effectiveness and safety of a new three-component 'bundle' for insertion and management of centrally inserted central catheters (CICCs), designed to minimize catheter-related bloodstream infections (CRBSIs) in critically ill children. METHODS: Our 'bundle' has three components: insertion, management, and education. Insertion and management recommendations include: skin antisepsis with 2% chlorhexidine; maximal barrier precautions; ultrasound-guided venipuncture; tunneling of the catheter when a long indwelling time is expected; glue on the exit site; sutureless securement; use of transparent dressing; chlorhexidine sponge dressing on the 7th day; neutral displacement needle-free connectors...
November 8, 2017: Journal of Vascular Access
Sophie J Balk, Elizabeth A Gottschlich, Dawn M Holman, Meg Watson
BACKGROUND: The US Preventive Services Task Force recommends clinical counseling for individuals ages 10 to 24 years to decrease skin cancer risk. METHODS: A national, random sample of US American Academy of Pediatrics members practicing primary care in 2002 (response rate 55%) and 2015 (response rate 43%). Surveys explored attitudes and experiences regarding sun protection counseling; indoor tanning questions were added in 2015. χ2 tests compared demographics and counseling responses across years, and multivariable logistic regression models examined counseling predictors...
December 2017: Pediatrics
Francesca Cipriani, Carla Mastrorilli, Salvatore Tripodi, Giampaolo Ricci, Serena Perna, Valentina Panetta, Riccardo Asero, Arianna Dondi, Annamaria Bianchi, Nunzia Maiello, Michele Miraglia Del Giudice, Tullio Frediani, Francesco Macrì, Sandra Lucarelli, Iride Dello Iacono, Maria Francesca Patria, Elena Varin, Diego Peroni, Loredana Chini, Viviana Moschese, Roberto Bernardini, Giuseppe Pingitore, Umberto Pelosi, Mariangela Tosca, Francesco Paravati, Ifigenia Sfika, Andrea Di Rienzo Businco, Calotta Povesi Dascola, Pasquale Comberiati, Simone Frediani, Caterina Lambiase, Maria Carmen Verga, Diego Faggian, Mario Plebani, Mauro Calvani, Carlo Caffarelli, Paolo Maria Matricardi
BACKGROUND: Grass pollen-related seasonal allergic rhinoconjunctivitis (SARg) is clinically heterogeneous in severity, comorbidities and response to treatment. The component-resolved diagnostics disclosed also a high heterogeneity at molecular level. Our study aimed at analyzing the characteristics of the IgE sensitization to Phleum pratense molecules and investigating the diagnostic relevance of such molecules in childhood. METHODS: We examined 1120 children (age 4-18y) with SARg...
October 20, 2017: Allergy
Anish Nadkarni, Leah A Cardwell, Simon Mahler, Steven R Feldman
Skin related complaints are a top 10 reason for pediatric presentation to the ED. Older studies and those conducted outside of the US demonstrate wide variability in the frequency of pediatric presentations to the ED for skin complaints, ranging from 4-40% of visits.(1) One study found urticaria to be the most frequent PED dermatological diagnosis, while others found viral exanthema and contact dermatitis to be the most common diagnoses. This article is protected by copyright. All rights reserved.
October 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
Yunjie Zhang, Shuang Jiang, Hongxia Chen, Xianbiao Zou
Port-wine stain is a type of common congenital superficial telangiectasia in the dermal layer mostly occurring on the forehead, face, and neck. The affected skin shows abnormal red or purple lesions, which darken and thicken. Nodular changes may develop with advancing age. If untreated, port-wine stains scarcely regress, which can have serious lifelong psychological impact on patients and affect their quality of life. In this report, we focused on two cases of port-wine stain in pediatric patients; the youngest patient was only 1...
July 2017: Anais Brasileiros de Dermatologia
Dario O Fauza
Transamniotic stem cell therapy, or TRASCET, is an emerging therapeutic concept for the management of congenital anomalies based on the augmentation of the biological role of select populations of stem cells that already occur in the amniotic fluid, for targeted therapeutic benefit. Amniotic fluid-derived mesenchymal stem cells (afMSCs) have a central role in the enhanced ability of the fetus to repair tissue damage. This germane recent finding constitutes the biological foundation for the use of afMSCs in TRASCET...
October 11, 2017: Pediatric Research
Luis Moral, Jean-Christoph Caubet
Suspected allergy to penicillins and cephalosporins is very common in childhood. After a proper evaluation, allergy will be confirmed only in a small portion of them. Intradermal tests are usually part of the allergy workup, but they are painful for children and time-consuming, and their role has been debated. A systematic review found only two studies reporting a positive predictive value of skin tests in children of 36% and 33%, respectively, leading to a high rate of inaccurate diagnosis. Moreover, considering that skin tests are negative in more than 90%-95% of cases, an oral provocation test (OPT) is finally needed to confirm tolerance in most of these children...
September 11, 2017: Pediatric Allergy and Immunology
Fleta N Bray, Sebastian H Verne, Jessica Cervantes, Alexandra Balaban, Eric R Bray, Brian J Simmons, Keyvan Nouri
Children who are not adequately protected from the sun have an increased risk for developing skin cancers later in life. The primary objective of this study was to determine the sun protection behaviors that black and Hispanic parents in Miami, Florida, employ in infants younger than 6 months. Secondary objectives included determining if this patient population is at risk for infant sunburns and tanning, beliefs among parents regarding sunscreen's efficacy in the prevention of skin cancers, and limitations of sunscreen use...
May 2017: Cutis; Cutaneous Medicine for the Practitioner
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