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red wine and health

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https://www.readbyqxmd.com/read/29079840/selective-colorimetric-detection-of-nitrite-in-water-using-chitosan-stabilized-gold-nanoparticles-decorated-reduced-graphene-oxide
#1
Baishnisha Amanulla, Selvakumar Palanisamy, Shen-Ming Chen, Te-Wei Chiu, Vijayalakshmi Velusamy, James M Hall, Tse-Wei Chen, Sayee Kannan Ramaraj
Excess nitrite (NO2(-)) concentrations in water supplies is considered detrimental to the environment and human health, and is associated with incidence of stomach cancer. In this work, the authors describe a nitrite detection system based on the synthesis of gold nanoparticles (AuNPs) on reduced graphene oxide (rGO) using an aqueous solution of chitosan and succinic acid. The AuNPs-rGO nanocomposite was confirmed by different physicochemical characterization methods including transmission electron microscopy, elemental analysis, X-ray diffraction, UV-visible (UV-vis) and Fourier transform infrared spectroscopy...
October 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29074616/resveratrol-a-novel-type-of-topoisomerase-ii-inhibitor
#2
Joyce H Lee, Timothy J Wendorff, James M Berger
Resveratrol, a polyphenol found in various plant sources, has gained attention as a possible agent responsible for the purported health benefits of certain foods, such as red wine. Despite annual multi-million dollar market sales as a nutriceutical, there is little consensus about the physiological roles of resveratrol. One suggested molecular target of resveratrol is eukaryotic topoisomerase II (topo II), an enzyme essential for chromosome segregation and DNA supercoiling homeostasis. Interestingly, resveratrol is chemically similar to ICRF-187, a clinically-approved chemotherapeutic that stabilizes an ATP-dependent dimerization interface in topo II to block enzyme activity...
October 26, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29066884/trans-resveratrol-loaded-nonionic-lamellar-liquid-crystalline-systems-structural-rheological-mechanical-textural-and-bioadhesive-characterization-and-evaluation-of-in-vivo-anti-inflammatory-activity
#3
Bruno Fonseca-Santos, Cínthia Yuka Satake, Giovana Maria Fioramonti Calixto, Aline Martins Dos Santos, Marlus Chorilli
Resveratrol (Res) is a common phytoalexin present in a few edible materials, such as grape skin, peanuts, and red wine. Evidence has shown the beneficial effects of Res on human health, which may be attributed to its anti-inflammatory activity. However, the poor aqueous solubility of Res limits its therapeutic effectiveness. Therefore, the use of nanostructured delivery systems for Res, such as liquid-crystalline systems, could be beneficial. In this study, we aimed to develop, characterize, and determine the in vivo effectiveness of Res-loaded liquid-crystalline systems...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29054583/dietary-resveratrol-increases-mid-life-fecundity-of-female-nothobranchius-guentheri
#4
Youngjoo Lee, Andrew C Drake, Nicholas O Thomas, Lindsey G Ferguson, Patrick E Chappell, Kate Petersen Shay
The decline of female reproductive function is an early phenotype of aging in humans, occurring only midway through the lifespan. Yet the number of women delaying pregnancy continues to rise in industrialized societies due to personal or socioeconomic circumstances, often resulting in subfertility or difficulty conceiving. There are few defined mechanisms associated with this etiology, and equally few effective therapies. To combat this problem, we used a novel emerging model, Nothobranchius guentheri, that recapitulates the age-associated spectrum of changes that adversely affect human fertility...
October 17, 2017: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/28993373/wine-and-cardiovascular-health-a-comprehensive-review
#5
REVIEW
Sohaib Haseeb, Bryce Alexander, Adrian Baranchuk
Alcoholic beverages have been consumed for thousands of years, attracting great human interest for social, personal, and religious occasions. In addition, they have long been debated to confer cardioprotective benefits. The French Paradox is an observation of a low prevalence of ischemic heart disease, with high intakes of saturated fat, a phenomenon accredited to the consumption of red wine. Although many epidemiological investigations have supported this view, others have attributed it to beer or spirits, with many suggesting that the drink type is not important...
October 10, 2017: Circulation
https://www.readbyqxmd.com/read/28954417/modulation-of-nrf2-by-olive-oil-and-wine-polyphenols-and-neuroprotection
#6
REVIEW
Miriam Martínez-Huélamo, Jose Rodríguez-Morató, Anna Boronat, Rafael de la Torre
Strong adherence to a Mediterranean diet is associated with improved cognitive function and a lower prevalence of mild cognitive impairment. Olive oil and red wine are rich sources of polyphenols which are responsible in part for the beneficial effects on cognitive functioning. Polyphenols induce endogenous antioxidant defense mechanisms by modulating transcription factors such as the nuclear factor (erythroid-derived 2)-like 2 (Nrf2). This review discusses the scientific data supporting the modulating effect of olive oil and red wine polyphenols on Nrf2 expression, and the potential health benefits associated with cognitive functioning...
September 26, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28911531/biological-actions-and-molecular-effects-of-resveratrol-pterostilbene-and-3-hydroxypterostilbene
#7
REVIEW
Hui-Yun Tsai, Chi-Tang Ho, Yu-Kuo Chen
Stilbenes are a class of polyphenolic compounds, naturally found in a wide variety of dietary sources such as grapes, berries, peanuts, red wine, and some medicinal plants. There are several well-known stilbenes including trans-resveratrol, pterostilbene, and 3'-hydroxypterostilbene. The core chemical structure of stilbene compounds is 1,2-diphenylethylene. Recently, stilbenes have attracted extensive attention and interest due to their wide range of health-beneficial effects such as anti-inflammation, -carcinogenic, -diabetes, and -dyslipidemia activities...
January 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28893620/protective-effects-of-tea-red-wine-and-cocoa-in-diabetes-evidences-from-human-studies
#8
REVIEW
Maria Angeles Martin, Luis Goya, Sonia Ramos
Prevention of diabetes through the diet has recently received an increasing interest, and polyphenolic compounds, such as flavanols, have become important potential chemopreventive natural agents due to their proved benefits on health, with low toxicity and cost. Tea, red wine and cocoa are good sources of flavanols and these highly consumed foods might contribute to prevent diabetes. In this regard, there is increasing evidence for a protective effect of tea, red wine and cocoa consumption against this disorder...
September 8, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28865736/association-between-inflammatory-diet-pattern-and-risk-of-colorectal-carcinoma-subtypes-classified-by-immune-responses-to-tumor
#9
Li Liu, Reiko Nishihara, Zhi Rong Qian, Fred K Tabung, Daniel Nevo, Xuehong Zhang, Mingyang Song, Yin Cao, Kosuke Mima, Yohei Masugi, Yan Shi, Annacarolina da Silva, Tyler Twombly, Mancang Gu, Wanwan Li, Tsuyoshi Hamada, Keisuke Kosumi, Kentaro Inamura, Jonathan A Nowak, David A Drew, Paul Lochhead, Katsuhiko Nosho, Kana Wu, Molin Wang, Wendy S Garrett, Andrew T Chan, Charles S Fuchs, Edward L Giovannucci, Shuji Ogino
BACKGROUND & AIMS: Dietary patterns affect systemic and local intestinal inflammation, which have been linked to colorectal carcinogenesis. Chronic inflammation can interfere with the adaptive immune response. We investigated whether the association of a diet that promotes intestinal inflammation with risk of colorectal carcinoma was stronger for tumors with lower lymphocytic reactions than tumors with higher lymphocytic reactions. METHODS: We collected data from the molecular pathological epidemiology databases of 2 prospective cohort studies: the Nurses' Health Study (since 1976) and the Health Professionals Follow-Up Study (since 1986)...
September 1, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28841237/singlet-oxygen-detection-using-red-wine-extracts-as-photosensitizers
#10
Irene Lagunes, Fernanda Vázquez-Ortega, Ángel Trigos
Moderate consumption of red wine provides beneficial effects to health. This is attributed to polyphenol compounds present in wine such as resveratrol, quercetin, gallic acid, rutin, and vanillic acid. The amount of these antioxidants is variable; nevertheless, the main beneficial effects of red wine are attributed to resveratrol. However, it has been found that resveratrol and quercetin are able to photosensitize singlet oxygen generation and conversely, gallic acid acts as quencher. Therefore, and since resveratrol and quercetin are some of the most important antioxidants reported in red wines, the aim of this research was to evaluate the photosensitizing ability of 12 red wine extracts through photo-oxidation of ergosterol...
August 25, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28833163/control-of-native-spoilage-yeast-on-dealcoholized-red-wine-by-preservatives-alone-and-in-binary-mixtures
#11
Marta Sánchez-Rubio, Kamal Guerrouj, Amaury Taboada-Rodríguez, Antonio López-Gómez, Fulgencio Marín-Iniesta
In order to preserve a commercial dealcoholized red wine (DRW), a study with 4 preservatives and binary mixtures of them were performed against 2 native spoilage yeasts: Rhodotorula mucilaginosa and Saccharomyces cerevisiae. Minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) for potassium sorbate, sodium benzoate, sodium metabisulfite and dimethyl dicarbonate (DMDC) were evaluated in DRW stored at 25 °C. MICs of potassium sorbate and sodium metabisulfite were 250 and 60 mg/kg, respectively for both target strains...
August 23, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28796948/identification-of-polyphenol-specific-innate-epitopes-that-originated-from-a-resveratrol-analogue
#12
Mai Furuhashi, Yukinori Hatasa, Sae Kawamura, Takahiro Shibata, Mitsugu Akagawa, Koji Uchida
Polyphenols have received a significant amount of attention in disease prevention because of their unique chemical and biological properties. However, the underlying molecular mechanism for their beneficial effects remains unclear. We have now identified a polyphenol as a source of innate epitopes detected in natural IgM and established a unique gain-of-function mechanism in the formation of innate epitopes by polyphenol via the polymerization of proteins. Upon incubation with bovine serum albumin (BSA) under physiological conditions, several polyphenols converted the protein into the innate epitopes recognized by the IgM Abs...
September 5, 2017: Biochemistry
https://www.readbyqxmd.com/read/28733233/estimation-of-dietary-intake-and-target-hazard-quotients-for-metals-by-consumption-of-wines-from-the-canary-islands
#13
Angel J Gutiérrez, Carmen Rubio, Isabel M Moreno, A Gustavo González, Dailos Gonzalez-Weller, Naouel Bencharki, Arturo Hardisson, Consuelo Revert
This paper describes the impact of mineral content on wines and assesses the potential health risk from consuming these wines from Canary Islands. The metal content (B, Ca, Co, Cr, Cu, Fe, K, Li, Mg, Mn, Mo, Na, Ni, Pb, Zn) of red wines belonging to different regions in the Canary Islands was determined by ICP-OES. The studied wine regions were Valle de la Orotava, Tacoronte-Acentejo, Ycoden-Daute-Isora, Abona and Valle de Güimar in Tenerife Island and only one in La Gomera and La Palma Islands. According to the content found, elements could be classified in two categories: the main group including Ca, K, Mg, Na, and the ''minor'' set consisting of B, Co, Cr, Cu, Fe, Li, Mn, Mo, Ni, Pb and Zn...
July 19, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28721728/reduced-production-of-higher-alcohols-by-saccharomyces-cerevisiae-in-red-wine-fermentation-by-simultaneously-overexpressing-bat1-and-deleting-bat2
#14
Lijuan Ma, Shiyong Huang, Liping Du, Ping Tang, Dongguang Xiao
In red wine, the contents of higher alcohols and ethyl carbamate (EC) are two significant health concerns. To reduce the production of higher alcohols by wine yeast YZ22 with low production of EC, one BAT2 was replaced by a BAT1 expression cassette first and then another BAT2 was deleted to obtain the mutant SYBB3. Real-time quantitative PCR showed that the relative expression level of BAT1 in SYBB3 improved 28 times compared with that in YZ22. The yields of isobutanol and 3-methyl-1-butanol produced by mutant SYBB3 reduced by 39...
August 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28718057/immobilized-enzymes-from-geotrichum-spp-improve-wine-quality
#15
Yao Lu, Jing Zhu, Junling Shi, Yanlin Liu, Dongyan Shao, Chunmei Jiang
Higher alcohols are the byproducts of yeasts in alcohol fermentation and are harmful to human health at high concentrations. In this study, immobilized crude enzymes extracted from Geotrichum spp. strains S12 and S13 were separately employed to treat red wine, then GC and GC-MS analyses were used to determine the profiles of volatile compounds in untreated and treated wine samples. Immobilized enzymes from S13 (SA-S13E) were more active in decreasing higher alcohols than enzymes from S12. Conditions for preparing SA-S13E were optimized, and best results were obtained at a sodium alginate concentration of 35 g/L, calcium chloride of 20 g/L, and crude enzyme dosage of 3 mL...
July 17, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28702941/an-application-of-partial-least-squares-for-identifying-dietary-patterns-in-bone-health
#16
Tiffany C Yang, Lorna S Aucott, Garry G Duthie, Helen M Macdonald
In a large cohort of older women, a mechanism-driven statistical technique for assessing dietary patterns that considers a potential nutrient pathway found two dietary patterns associated with lumbar spine and femoral neck bone mineral density. A "healthy" dietary pattern was observed to be beneficial for bone mineral density. INTRODUCTION: Dietary patterns represent a broader, more realistic representation of how foods are consumed, compared to individual food or nutrient analyses. Partial least-squares (PLS) is a data-reduction technique for identifying dietary patterns that maximizes correlation between foods and nutrients hypothesized to be on the path to disease, is more hypothesis-driven than previous methods, and has not been applied to the study of dietary patterns in relation to bone health...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28683524/enhancing-the-antioxidant-activities-of-wines-by-addition-of-white-rose-extract
#17
Hyunbin Seong, Jieun Heo, Kyun Hee Lee, Yoon Bok Lee, Yun Bae Kim, Nam Soo Han
White rose petal extract (WRE) contains large amounts of phenolic compounds and is considered edible. In this study, red and white wines were prepared by the addition of WRE (0.10% or 0.25% (w/v)), followed by fermentation at 25°C for 15 days. The fermentation profiles, colors, sensory test results, and antioxidant activities of the wines were compared. As reported herein, the fermentation profiles of the pH, CO₂ production rate, and final ethanol concentration were not affected by the addition of WRE, but a slow consumption rate of sugar was observed in 0...
September 28, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28677796/resveratrol-suppresses-thyroid-hormone%C3%A2-induced-osteocalcin-synthesis-in-osteoblasts
#18
Kazuhiko Fujita, Haruhiko Tokuda, Shingo Kainuma, Gen Kuroyanagi, Naohiro Yamamoto, Rie Matsushima-Nishiwaki, Atsushi Harada, Osamu Kozawa, Takanobu Otsuka
Resveratrol, a polyphenolic compound that is present in grape skins, berries and red wine, may be beneficial for human health through its anti‑inflammatory and anti‑oxidant effects. It has been previously demonstrated that resveratrol exerts its biological effects primarily via sirtuin 1 (SIRT1) activation. We previously reported that triiodothyronine (T3) induces osteocalcin synthesis in osteoblast‑like MC3T3‑E1 cells, and that p38 mitogen‑activated protein (MAP) kinase mediates the T3‑stimulated synthesis of osteocalcin...
September 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28638763/the-hidden-face-of-wine-polyphenol-polymerization-highlighted-by-high-resolution-mass-spectrometry
#19
Anna Vallverdú-Queralt, Emmanuelle Meudec, Matthias Eder, Rosa M Lamuela-Raventos, Nicolas Sommerer, Véronique Cheynier
Polyphenols, including tannins and red anthocyanin pigments, are responsible for the color, taste, and beneficial health properties of plant-derived foods and beverages, especially in red wines. Known compounds represent only the emerged part of the "wine polyphenol iceberg". It is believed that the immersed part results from complex cascades of reactions involving grape polyphenols and yeast metabolites. We used a non-targeted strategy based on high-resolution mass spectrometry and Kendrick mass defect plots to explore this hypothesis...
June 2017: ChemistryOpen
https://www.readbyqxmd.com/read/28610729/targeted-and-untargeted-high-resolution-mass-approach-for-a-putative-profiling-of-glycosylated-simple-phenols-in-hybrid-grapes
#20
Chiara Barnaba, Eduardo Dellacassa, Giorgio Nicolini, Mattia Giacomelli, Tomas Roman Villegas, Tiziana Nardin, Roberto Larcher
Vitis vinifera is one of the most widespread grapevines around the world representing the raw material for high quality wine production. The availability of more resistant interspecific hybrid vine varieties, developed from crosses between Vitis vinifera and other Vitis species, has generated much interest, also due to the low environmental effect of production. However, hybrid grape wine composition and varietal differences between interspecific hybrids have not been well defined, particularly for the simple phenols profile...
August 2017: Food Research International
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