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signet ring carcinoma

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https://www.readbyqxmd.com/read/29672365/the-impact-of-epidemiological-factors-and-treatment-interventions-on-survival-in-patients-with-signet-ring-cell-carcinoma-of-the-pancreas
#1
Mausam Patel, Harliv S Hans, Kelsey Pan, Humza Khan, Elie Donath, Humberto Caldera
OBJECTIVES: Primary pancreatic signet ring cell carcinoma (SRCC) is a rare histologic variant of pancreatic carcinoma. A population-based analysis of pancreatic SRCC was performed to determine the predictive effects of epidemiological factors and treatment interventions on overall survival (OS) and disease-specific survival (DSS). MATERIALS AND METHODS: The Surveillance, Epidemiology, and End Results registry was searched for pancreatic SRCC cases diagnosed between January 1, 1973 and December 31, 2013...
April 18, 2018: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29658333/mucinous-breast-carcinoma-with-tall-columnar-cells
#2
N Tsoukalas, M Kiakou, M Tolia, I D Kostakis, M Galanopoulos, G Nakos, D Tryfonopoulos, G Kyrgias, G Koumakis
Mucinous carcinoma of the breast represents 1%-4% of all breast cancers. The World Health Organization classification divides this type of tumour into three different subtypes: mucinous carcinoma, mucinous carcinoma with tall columnar cells (mucinous cystadenocarcinoma and columnar cell mucinous carcinoma) and signet ring cell carcinoma. A 74-year-old woman presented a tumour with inflammatory features in the upper outer quadrant of her left breast, 7 cm in diameter. The core biopsy showed infiltrating ductal carcinoma of no specific type...
April 16, 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29643292/-a-case-of-postoperative-recurrent-gastric-cancer-resembling-esophageal-achalasia-diagnosed-by-staging-laparoscopy
#3
Masayuki Kabayama, Fumisato Sasaki, Hidehito Maeda, Shiho Arima, Shiroh Tanoue, Yuichiro Nasu, Shinichi Hashimoto, Shuji Kanmura, Jun Kadono, Akio Ido
A 65-year-old man underwent subtotal gastrectomy for advanced gastric cancer. The histological type of the cancer was signet-ring cell carcinoma, and the clinical stage was stage IB (T2N0M0). Three years after surgery, the patient had the following symptoms:dysphagia, odynophagia, and weight loss. Esophageal endoscopy and esophagography revealed a circular stenosis covered with the normal mucosa between the middle esophagus and the esophagogastric junction. Histologically, the samples obtained by staging laparoscopy revealed signet-ring cell carcinoma...
2018: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/29600360/histopathological-assessment-for-esophageal-adenocarcinoma
#4
Alfred K Lam
In the World Health Organization (WHO) classification, adenocarcinoma of esophagus comprises preinvasive type (dysplasia), adenocarcinoma, adenoid cystic carcinoma, adenosquamous carcinoma, and mucoepidermoid carcinoma. For adenocarcinoma, it is important to determine the grading of the cancer and histological variants such as signet ring adenocarcinoma. In the current day management of esophageal adenocarcinoma by neoadjuvant therapy, the histology of the cancer and the lymph nodal status may change after the therapy...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29588604/primary-mucinous-carcinoma-of-thyroid-gland-with-prominent-signet-ring-cell-differentiation-a-case-report-and-review-of-the-literature
#5
Jian Wang, Qie-Re Guli, Xiao-Cui Ming, Hai-Tao Zhou, Yong-Jie Cui, Yue-Feng Jiang, Di Zhang, Yang Liu
Purpose: This study reports a case of primary mucinous carcinoma of the thyroid gland with signet-ring-cell differentiation, and reviews the literature to evaluate its real incidence and the prognosis of these patients. Patients and methods: A 74-year-old Chinese woman, presenting with a mass in the right lobe of thyroid gland, came to the hospital. Computed tomography revealed a mass in the right lobe of the thyroid gland, accompanied with right neck lymphadenectasis and airway deviation caused by tumor compression...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29572728/-68-ga-labelled-psma-prostate-specific-membrane-antigen-expression-in-signet-ring-cell-gastric-carcinoma
#6
Dharmender Malik, Rajender Kumar, Bhagwant Rai Mittal, Harmandeep Singh, Anish Bhattacharya, Ashwani Sood, Vishal Sharma, Harjeet Singh
No abstract text is available yet for this article.
March 23, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29572575/metastatic-colonic-and-gastric-polyps-from-breast-cancer-resembling-hyperplastic-polyps
#7
Yoshiya Horimoto, Tetsuro Hirashima, Atsushi Arakawa, Hiroyoshi Miura, Mitsue Saito
Breast cancer metastasis to the gastrointestinal tract is relatively rare and is generally found when patients complain of symptoms such as gastrointestinal obstruction. Herein, we report a case with metastatic colonic and gastric lesions from breast cancer, with the formation of mucosal polyps which resembled typical hyperplastic polyps.A 47-year-old woman underwent curable surgery for breast cancer and received standard systemic treatments. Her primary tumor was composed of a mix of invasive lobular and ductal carcinomas...
March 23, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29564177/investigation-of-targetable-predictive-and-prognostic-markers-in-gallbladder-carcinoma
#8
Azfar Neyaz, Nuzhat Husain, Sameer Gupta, Swati Kumari, Aditi Arora, Namrata Puneet Awasthi, Kiran Preet Malhotra, Sanjeev Misra
Background: Gallbladder carcinoma, uncommon in most of the world, is frequent in South East Asia. It presents in advanced stages with limited therapeutic options. We investigated targetable predictive and prognostic Markers in 268 cases including 233 primary site lesions and 35 metastatic gallbladder carcinoma. Methods: EGFR, VEGF, HER2/Neu and p53 were assessed using immunohistochemistry. HER2/Neu was validated in a subset by fluorescent in situ hybridization (FISH) using tissue microarray (TMA)...
February 2018: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29560294/basal-cell-carcinoma-with-myoepithelial-differentiation-case-report-and-literature-review
#9
Philip R Cohen
Basal cell carcinoma is the most common skin cancer. Myoepithelial cells are specialized epithelial cells. Basal cell carcinoma with myoepithelial differentiation is a rare tumor. A 71-year-old man with a basal cell carcinoma with myoepithelial differentiation that presented as an asymptomatic red papule of two months duration on his forehead is described. Including the reported patient, this variant of basal cell carcinoma has been described in 16 patients: 11 men and five women. The patients ranged in age at diagnosis from 43 years to 83 years; the median age at diagnosis was 66 years...
January 17, 2018: Curēus
https://www.readbyqxmd.com/read/29560010/primary-signet-ring-cell-carcinoma-of-rectum-diagnosed-by-boring-biopsy-in-combination-with-endoscopic-mucosal-resection
#10
Yoshito Hirata, Keishi Kanno, Nobusuke Kishikawa, Shinji Tomoda, Kazuki Kimura, Tomoki Kobayashi, Daisuke Miyamori, Yuichiro Otani, Masafumi Mizooka, Koji Arihiro, Shiro Oka, Shinji Tanaka, Susumu Tazuma
A 46-year-old man with severe back pain visited our hospital. Magnetic resonance imaging revealed extensive bone metastasis and rectal wall thickness. Colonoscopy revealed circumferential stenosis with edematous mucosa, suggesting colon cancer. However, histological findings of biopsy specimens revealed inflammatory cells but no malignant cells. The patient underwent endoscopic ultrasound, which demonstrated edematous wall thickness without destruction of the normal layer structure. After unsuccessful detection of neoplastic cells by boring biopsies, we performed endoscopic mucosal resection followed by boring biopsies that finally revealed signet ring cell carcinoma...
2018: Case Reports in Medicine
https://www.readbyqxmd.com/read/29553397/the-amount-of-cells-with-signet-ring-cell-morphology-has-a-prognostic-impact-in-poorly-cohesive-gastric-carcinoma
#11
M Bencivenga, E Treppiedi, G Verlato, V Mengardo, S Giacopuzzi, G de Manzoni
No abstract text is available yet for this article.
March 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29553388/signet-ring-cell-carcinoma-in-the-stomach-histopathological-definitions-and-response-to-therapy-assessment-the-urgent-need-for-an-international-consensus
#12
https://www.readbyqxmd.com/read/29533002/differences-in-clinicopathological-characteristics-and-computed-tomography-findings-between-signet-ring-cell-carcinoma-and-nonsignet-ring-cell-carcinoma-in-early-and-advanced-gastric-cancer
#13
Jian Chen, Rong Cai, Gang Ren, Jianxi Zhao, Huali Li, Chen Guo, Wenguang He, Xiangru Wu, Wenjie Zhang
Signet ring cell carcinoma (SRC) of the stomach is a histological type based on microscopic characteristics. SRC's clinicopathological characteristics and prognosis are still controversial. Our study is to describe the clinicopathological features and multidetector computed tomography (MDCT) findings of patients with SRC of the stomach in comparison with nonsignet ring cell adenocarcinoma (NSRC). We retrospectively analyzed data from 241 patients who had undergone curative gastrectomy, including 62 SRC and 179 NSRC...
March 13, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29533001/comparison-of-survival-between-right-sided-and-left-sided-colon-cancer-in-different-situations
#14
Miao-Zhen Qiu, Wen-Tao Pan, Jun-Zhong Lin, Zi-Xian Wang, Zhi-Zhong Pan, Feng-Hua Wang, Da-Jun Yang, Rui-Hua Xu
Mountain of studies has showed that right-sided colon cancer (RSCC) and left-sided colon cancer (LSCC) have different clinical presentation and biologic features and should be considered as two distinct disease entities. The survival difference between RSCC and LSCC remains controversial. Using Surveillance, Epidemiology, and End Results (SEER) database, we identified colon adenocarcinoma patients from 2004 to 2013. The 5-year cause-specific survival (CSS) was our primary endpoint. All statistical analyses were performed using the Intercooled Stata 13...
March 13, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29524972/sociodemographic-and-survival-disparities-for-histologic-variants-of-bladder-cancer
#15
Joshua S Jue, Tulay Koru-Sengul, Kevin J Moore, Feng Miao, Mahmoud Alameddine, Bruno Nahar, Sanoj Punnen, Dipen J Parekh, Chad R Ritch, Mark L Gonzalgo
INTRODUCTION: To investigate the impact of perioperative factors on overall survival among patients with histologic variants of bladder cancer treated with radical cystectomy. MATERIALS AND METHODS: The National Cancer Data Base was utilized to identify patients diagnosed with muscle-invasive bladder cancer (cT2-4, N0, M0) from 2004-2013. Variant histology bladder cancers (non-mucinous adenocarcinoma, mucinous/signet ring adenocarcinoma, micropapillary urothelial carcinoma, small cell carcinoma, and squamous cell carcinoma) were compared to urothelial carcinoma with respect to overall survival...
February 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29511150/gastroscopy-findings-in-a-patient-with-signet-ring-cell-carcinoma-and-late%C3%A2-onset-hereditary-hemochromatosis
#16
Marta Walczak-Gałęzewska, Monika Szulińska, Danuta Pupek-Musialik, Paweł Bogdański
No abstract text is available yet for this article.
February 28, 2018: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/29492918/-surgical-treatment-and-prognosis-of-borrmann-type-iiii-gastric-cancer-involving-the-whole-stomach
#17
Ruizeng Dong, Zewei Zhang, Yiming Zhou, Yonghong Hua, Jianmin Guo
OBJECTIVE: To explore the surgical treatment and prognosis of Borrmann type IIII( gastric cancer involving the whole stomach. METHODS: Clinicopathological characteristics and survival data of 223 patients with Borrmann type IIII( gastric cancer involving the whole stomach (defined as the tumor infiltrating 3 regions of the stomach) receiving surgical treatment at the Department of Abdominal Surgery of Zhejiang Cancer Hospital between January 2002 and December 2015 were analyzed retrospectively...
February 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29485442/should-18f-fdg-pet-ct-be-routinely-performed-in-the-clinical-staging-of-locally-advanced-gastric-adenocarcinoma
#18
Pilar Perlaza, Jaime Ortín, Mario Pagès, Elvira Buxó, Gloria Fernández-Esparrach, Patrick M Colletti, Domenico Rubello, Maria Mayoral, Nuria Sánchez, Cristina Ruiz, Angels Ginés, David Fuster
PURPOSE: The aim of this study was to evaluate F-FDG PET/CT compared with conventional imaging techniques in the clinical management of patients with locally advanced gastric cancer (LAGC). METHODS: A prospective study between January 2010 and December 2011 in patients with suspected LAGC was conducted in our hospital. F-FDG PET/CT, contrast-enhanced CT (CECT), endoscopic ultrasound, and laparoscopy were performed in all cases. Standard whole-body F-FDG PET/CT images were obtained centered on the stomach at 1 and 2 hours after injection of 4...
February 27, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29484053/mucinous-carcinoma-of-the-gallbladder-with-signet-ring-cells
#19
Takeshi Fukuda, Yoshihiro Sakimoto, Kenichi Narita, Mitsuko Ariizumi, Yoshio Aizawa, Kunihiko Fukuda
Most gallbladder carcinomas are adenocarcinomas, of which mucinous carcinoma (MC) is a rare pathologic subtype. Signet ring cells are seldom found in MCs. We report an extremely rare case of gallbladder MC with signet ring cells. This is the first radiological case report about this rare type of histologic entity with detailed discussion of imaging findings in the English literature. In addition to the features of MC, linitis plastica-like invasion, which is the key feature of signet ring cells, was confirmed by both imaging and histopathologic analysis...
December 2017: Radiology Case Reports
https://www.readbyqxmd.com/read/29465585/occurrence-of-signet-ring-cell-carcinoma-with-cholangiocarcinoma-25-years-after-choledochal-cyst-excision-a-case-report
#20
Conggui Zhang, Jianpeng Zhou, Kai Kou, Shouling Liu, Feng We, Guangyi Wang
RATIONALE: Choledochal cysts are a risk factor for the development of cholangiocarcinoma. Hence, complete surgical excision is the preferred treatment in most cases. However, cholangiocarcinoma still can develop from the remnant biliary system after surgical excision. Signet-ring cell carcinoma is a rare type of cancer of the biliary system, and the occurrence of signet-ring cell carcinoma after surgical excision of choledochal cysts has not been reported in the English literature to date...
February 2018: Medicine (Baltimore)
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