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https://www.readbyqxmd.com/read/29341952/a-pharmacological-review-leptadenia-reticulata-wight-arn-jivanti-the-real-life-giving-plant
#1
Jayesh M Dhalani, Pankaj B Nariya
The present review reveals a comprehensive description of various pharmacological studies carried out on Leptadenia reticulata, a source of several active compounds, i.e. Leptadenia reticulata plant belonging to family Asclepiadaceae, it is also known as 'Jivanti', used for the treatment of various ailments in human civilization as well as used in folk medicine as a remedy in various reported herbal formulations. The plant has been found to exhibit diverse pharmacological activities like antibacterial activity, anticancer activity, lactogenic eff ect, antioxidant activity, anti-implantation activity, anti-asthmatic activity, modulating eff ect, activity of silver nano particles, hepatoprotective activity, antifungal activity, antidiabetic activity and anti-infl ammatory activity...
December 20, 2017: Folia Medica
https://www.readbyqxmd.com/read/29241764/determining-the-effects-of-green-chemistry-synthesized-ag-nisin-nanoparticle-on-macrophage-cells
#2
Masood Moein, Abbas Ali Imani Fooladi, Hamideh Mahmoodzadeh Hosseini
Bacteriocins are low molecular weight substances produced through post transcriptional changes. These molecules are easily degraded in mammalian gut by proteolytic enzymes especially protease. Nisin is a peptide with 34 aa and its structure contains a pentacyclic lanthionine and 4 beta metyllanthionine residues. Different formulations have been designed for nisin. Since "green synthesis" is a progressive method to prepare anti-microbial and anti-cancer compounds, this study aimed at green synthesis of nisin metal compounds to be used lower concentration still exerting nisin effects...
December 11, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29220865/silver-nano-particles-ameliorate-learning-and-spatial-memory-of-male-wistar-rats-by-prevention-of-amyloid-fibril-induced-neurotoxicity
#3
H Ramshini, A-S Moghaddasi, L-S Aldaghi, N Mollania, A Ebrahim-Habibi
Alzheimer's disease (AD) is a chronic degenerative disease characterized by the presence of amyloid plaques and neurofibrillary tangles (NFTs), which results into memory and learning impairments. In the present study, we showed that the aggregates formed by a protein that has no link with Alzheimer's disease, namely the hen egg white lysozyme (HEWL), were cytotoxic and decreased spatial learning and memory in rats. The effect of Ag-nano particles (Ag-NPs) was investigated on disruption of amyloid aggregation and preservation of cognitive behavior of rats...
December 8, 2017: Archives Italiennes de Biologie
https://www.readbyqxmd.com/read/29220571/fluorescent-liquid-metal-as-transformable-biomimetic-chameleon
#4
Shuting Liang, Wei Rao, Kai Song, Jing Liu
Liquid metal (LM) is of core interest for a wide variety of newly emerging areas. However, the functional materials thus made so far by LM only could display a single silver-white appearance. In this study, colorful LM marbles working like transformable biomimetic robot were proposed for the first time and fabricated from LM droplets through encasing them with fluorescent nano-particles. We demonstrated that this unique LM marble can be manipulated into various stable magnificent appearances as one desires, and then splitt and merge among different colors...
December 8, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29215896/high-speed-but-not-magic-microwave-assisted-synthesis-of-ultra-small-silver-nanoparticles
#5
Patrick E J Saloga, Claudia Kästner, Andreas F Thünemann
Ever since reaction procedures are improved to achieve higher yields and shorter reaction times. One possibility consists in the usage of microwave reactors. In literature this is under discussion since they claim non-thermal effects resulting from the microwave radiation. Especially for the synthesis of nano-materials it is of crucial importance to be aware of influences on the reaction pathway. Therefore, we compare the syntheses of ultra-small silver nanoparticles via conventional and microwave heating. We employed a versatile one-pot polyol synthesis of poly(acrylic acid) (PAA) stabilized silver nanoparticles, which display superior catalytic properties...
December 7, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29196171/nano-silver-particle-synthesis-using-swertia-paniculata-herbal-extract-and-its-antimicrobial-activity
#6
Vivek Ahluwalia, Sasikumar Elumalai, Vinod Kumar, Sandeep Kumar, Rajender Singh Sangwan
In the present study, green synthesis of silver nanoparticles (AgNPs) was demonstrated using medicinal herb Swertia paniculata extract. The plant extract acted both as reducing and capping agents during synthesis process, where silver nitrate was used as silver source. Subsequent physico-chemical analysis revealed that particles had size range between 31 and 44 nm, and were spherical in shape. Among reaction parameters, temperature and time had significantly influenced the synthesis reaction. Also, synthesized nano particles were found stable up to 90 days...
November 28, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29178718/antimicrobial-and-antibiofilm-activity-of-silver-titanium-dioxide-and-iron-nano-particles
#7
Fatemeh Lavaee, Kiana Faez, Kioumars Faez, Nahal Hadi, Farzan Modaresi
PURPOSE: To compare the antimicrobial effects of chlorhexidine, penicillin, erythromycin, clindamycin, tetracycline and vancomycin with silver, titanium dioxide and iron nanoparticles and also to consider the synergistic antibacterial and antibiofilm effects of nanoparticles in clinical and standard strains of Streptococcus mutans and Streptococcus sanguinis. METHODS: The specimens collected from 66 3-5 year-old children with detected S. mutans and S. sanguinis by PCR were then exposed to the antimicrobial activity of chlorhexidine, penicillin, erythromycin, clindamycin, tetracycline and vancomycin with silver, titanium dioxide and iron nanoparticles measured by microdilution and disc diffusion tests and the colony counted after 1 to 5 minutes...
December 2016: American Journal of Dentistry
https://www.readbyqxmd.com/read/29171256/combination-of-redox-assembly-and-biomimetic-mineralization-to-prepare-graphene-based-composite-cellular-foams-for-versatile-catalysis
#8
Dong Yang, Zhao Jingjing, Jiafu Shi, Xueyan Wang, Shaohua Zhang, Zhongyi Jiang
Graphene-based materials with hierarchical structures and multi-functionality have gained diverse of interests in a variety of applications. Herein, we report a facile, yet universal approach to prepare graphene-based composite cellular foams (GCCFs) through combination of redox assembly and biomimetic mineralization enabled by cationic polymers. Specifically, cationic polymer (e.g., polyethyleneimine, lysozyme, etc.) could not only reduce and simultaneously assemble graphene oxide (GO) into cellular foams, but also confer the cellular foams with mineralization-inducing capability, enabling the formation of inorganic nanoparticles (e...
November 24, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29170043/green-synthesis-of-silver-nano-particles-from-atalantia-monophylla-l-correa-leaf-extract-their-antimicrobial-activity-and-sensing-capability-of-h2o2
#9
S Mahadevan, S Vijayakumar, P Arulmozhi
In the present study deals with the green synthesis of silver nano particles from methanolic leaf extracts of Atalantia monophylla. The synthesized nano-particles are characterized by UV-vis spectroscopy, PL, FTIR, XRD, SEM with EDAX and TEM. The nano-particles are indicated in absorption peak at 404 nm in the absorption spectrum. Further micro graphical analysis confirmed the average size was estimated about 35 nm and SEAD pattern authorized well crystalline materials. The FTIR studies help to confirm the functional group of synthesized silver nano particles...
November 20, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29155361/silver-nanoparticles-increase-bactericidal-activity-and-radical-oxygen-responses-against-bacterial-pathogens-in-human-osteoclasts
#10
Valerie Aurore, Fabienne Caldana, Marianne Blanchard, Solange Kharoubi Hess, Nils Lannes, Pierre-Yves Mantel, Luis Filgueira, Michael Walch
Bone infections are difficult to treat and can lead to severe tissue destruction. Acute bone infections are usually caused by Staphylococcus aureus. Osteoclasts, which belong to the monocyte/macrophage lineage, are the key cells in bone infections. They are not well equipped for killing bacteria and may serve as a reservoir for bacterial pathogens. Silver has been known for centuries for its bactericidal activity. Here, we investigated the bactericidal effects of nano-silver particles in bacteria infected human osteoclasts...
November 16, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/29151644/preparation-characterization-and-antimicrobial-properties-of-chitosan-silver-nanocomposites-films-against-fish-pathogenic-bacteria-and-fungi
#11
S H S Dananjaya, D C M Kulatunga, G I Godahewa, Chamilani Nikapitiya, Chulhong Oh, Madurani Edussuriya, Jehee Lee, Mahanama De Zoysa
Abstract: Development of nanostructured films using natural polymers and metals has become a considerable interest in various biomedical applications. Objective of the present study was to develop silver nano particles (AgNPs) embedded chitosan films with antimicrobial properties. Based on the Ag content, two types of chitosan silver nano films, named as CAgNfs-12 (12 mM) and CAgNfs-52 (52 mM) were prepared and characterized. Field emission scanning electron microscope (FE-SEM) images of two CAgNfs showed the circular AgNPs, which were uniformly embedded and distributed in the matrix of chitosan films...
December 2017: Indian Journal of Microbiology
https://www.readbyqxmd.com/read/29110458/simultaneous-rayleigh-mie-and-raman-fluorescence-characterization-of-molecularly-functionalized-colloids-by-correlative-single-particle-real-time-imaging-in-suspension
#12
Jörg Wissler, Martin Wehmeyer, Sandra Bäcker, Shirley K Knauer, Sebastian Schlücker
Many applications of nano- and microparticles require molecular functionalization. Assessing the heterogeneity of a colloidal sample in terms of its molecular functionalization is highly desirable, but not accessible by conventional ensemble experiments. Retrieving this information necessitates single-particle experiments which simultaneously detect both functionalized and non-functionalized particles via two separate imaging channels. In this contribution, we present an optical setup for performing correlative single-particle imaging using laser light-sheet illumination: the first detection channel records elastic light scattering (Rayleigh/Mie), while the second channel detects inelastic light scattering (Raman) or fluorescence...
November 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29104980/determining-molecular-orientation-via-single-molecule-sers-in-a-plasmonic-nano-gap
#13
Addison R L Marshall, Jamie Stokes, Francesco N Viscomi, John E Proctor, Johannes Gierschner, Jean-Sebastien G Bouillard, Ali M Adawi
In this work, plasmonic nano-gaps consisting of a silver nanoparticle coupled to an extended silver film have been fully optimized for single molecule Surface-Enhanced Raman Scattering (SERS) spectroscopy. The SERS signal was found to be strongly dependent on the particle size and the molecule orientation with respect to the field inside the nano-gap. Using Finite Difference Time Domain (FDTD) simulations to complement the experimental measurements, the complex interplay between the excitation enhancement and the emission enhancement of the system as a function of particle size were highlighted...
November 16, 2017: Nanoscale
https://www.readbyqxmd.com/read/29055734/development-of-copolymeric-nanoparticles-of-hypocrellin-b-enhanced-phototoxic-effect-and-ocular-distribution
#14
Venkateshwaran Krishnaswami, Chandrasekar Ponnusamy, Senthilkumar Sankareswaran, Muthuselvam Paulsamy, Madi Madiyalakan, Rajaguru Palanisamy, Ruckmani Kandasamy, Subramanian Natesan
In the present work, we have developed a photosensitizer hypocrellin B (HB) and nano silver loaded PLGA-TPGS nanoparticles with improved singlet oxygen production for enhanced photodynamic effect for the efficient treatment of age related macular degeneration. Random copolymer (PLGA-TPGS) synthesized by ring opening and bulk polymerization was characterized by IR, (1)H NMR and TGA analysis. HBS-CP-NPs prepared by nanoprecipitation techniques were spherical shaped 89.6-753.6nm size particles with negative zeta potential...
October 18, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29050591/benign-development-of-cotton-with-antibacterial-activity-and-metal-sorpability-through-introduction-amino-triazole-moieties-and-agnps-in-cotton-structure-pre-treated-with-periodate
#15
Amina L Mohamed, Ahmed G Hassabo, S Shaarawy, A Hebeish
The research work presented herein was undertaken with a view to develop, characterize and highlight modified cotton fabrics that acquire durable antibacterial activity in concomitant with high metal sorption capacity. The development is based on reacting cotton cellulose previously oxidized by sodium periodate-with 4 amino-1,2,4 triazole in presence and absence of silver nano particles (AgNPs). The idea behind the periodate pretreatment is to convert (via oxidative cleavge) the 2,3-vicinal diol of the anhydroglucose units of cotton into aldehyde groups...
December 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29026613/a-case-of-generalized-argyria-presenting-with-muscle-weakness
#16
Inha Jung, Eun-Jeong Joo, Byung Seong Suh, Cheol-Bae Ham, Ji-Min Han, You-Gyung Kim, Joon-Sup Yeom, Ju-Yeon Choi, Ji-Hye Park
BACKGROUND: Argyria is a rare irreversible cutaneous pigmentation disorder caused by prolonged exposure to silver. Herein, we report a case of generalized argyria that developed after chronic ingestion of soluble silver-nano particles and presented with muscle weakness. CASE PRESENTATION: A 74-year-old woman visited our emergency room, complaining of fever and mental deterioration. She was diagnosed with acute pyelonephritis and recovered after antibiotic therapy...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28980932/estimating-the-modulatory-effect-of-cadmium-chloride-on-the-genotoxicity-and-mutagenicity-of-silver-nanoparticles-in-mice
#17
H R H Mohamed
Silver (Ag) nanoparticles (nano-Ag) are widely used because of their distinctive antimicrobial properties, but this widespread use increases Ag release into the environment along with many other pollutants such as heavy metals. Therefore, this study was undertaken to study the modulatory effect of cadmium chloride (CdCl2) on the genotoxicity and mutagenicity of nano-Ag in mice liver, kidney and brain tissues. Co-injections of CdCl2 (1.5 mg/kg) with nano-Ag (20, 41, or 82 mg/kg) resulted in significant elevations in both single and double DNA strand breaks that triggered higher apoptotic DNA damage, as revealed by the more fragmented appearance of genomic DNA and the significant increase in apoptotic fractions...
September 30, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28963525/phyto-mediated-metallic-nano-architectures-via-melissa-officinalis-l-synthesis-characterization-and-biological-properties
#18
Irina Fierascu, Milen I Georgiev, Alina Ortan, Radu Claudiu Fierascu, Sorin Marius Avramescu, Daniela Ionescu, Anca Sutan, Alexandru Brinzan, Lia Mara Ditu
The development of methods for obtaining new materials with antimicrobial properties, based on green chemistry principles has been a target of research over the past few years. The present paper describes the phyto-mediated synthesis of metallic nano-architectures (gold and silver) via an ethanolic extract of Melissa officinalis L. (obtained by accelerated solvent extraction). Different analytic methods were applied for the evaluation of the extract composition, as well as for the characterization of the phyto-synthesized materials...
September 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28958187/nano-sized-zinc-oxide-and-silver-but-not-titanium-dioxide-induce-innate-and-adaptive-immunity-and-antiviral-response-in-differentiated-thp-1-cells
#19
Wing-Lam Poon, Harri Alenius, Joseph Ndika, Vittorio Fortino, Vesa Kolhinen, Arūnas Meščeriakovas, Mingfu Wang, Dario Greco, Anna Lähde, Jorma Jokiniemi, Jetty Chung-Yung Lee, Hani El-Nezami, Piia Karisola
Nano-sized metal oxides are currently the most manufactured nanomaterials (NMs), and are increasingly used in consumer products. Recent exposure data reveal a genuine potential for adverse health outcomes for a vast array of NMs, however the underlying mechanisms are not fully understood. To elucidate size-related molecular effects, differentiated THP-1 cells were exposed to nano-sized materials (n-TiO2, n-ZnO and n-Ag), or their bulk-sized (b-ZnO and b-TiO2) or ionic (i-Ag) counterparts, and genome-wide gene expression changes were studied at low-toxic concentrations (<15% cytotoxicity)...
September 29, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/28929768/protein-corona-analysis-of-silver-nanoparticles-links-to-their-cellular-effects
#20
Sabine Juling, Alicia Niedzwiecka, Linda Böhmert, Dajana Lichtenstein, Sören Selve, Albert Braeuning, Andreas F Thünemann, Eberhard Krause, Alfonso Lampen
The breadth of applications of nanoparticles and the access to food-associated consumer products containing nanosized materials lead to oral human exposure to such particles. In biological fluids nanoparticles dynamically interact with biomolecules and form a protein corona. Knowledge about the protein corona is of great interest for understanding the molecular effects of particles as well as their fate inside the human body. We used a mass spectrometry-based toxicoproteomics approach to elucidate mechanisms of toxicity of silver nanoparticles and to comprehensively characterize the protein corona formed around silver nanoparticles in Caco-2 human intestinal epithelial cells...
October 6, 2017: Journal of Proteome Research
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