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https://www.readbyqxmd.com/read/28526794/raffinose-induces-biofilm-formation-by-streptococcus-mutans-in-low-concentrations-of-sucrose-by-increasing-production-of-extracellular-dna-and-fructan
#1
Ryo Nagasawa, Tsutomu Sato, Hidenobu Senpuku
Streptococcus mutans is the primary etiological agent of dental caries and causes tooth decay by forming a firmly attached biofilm on tooth surfaces. Biofilm formation is induced by the presence of sucrose, which is a substrate for the synthesis of extracellular polysaccharides, but not in the presence of oligosaccharides. Nonetheless, in this study, we found that raffinose, which is an oligosaccharide with an intestinal regulatory function and antiallergic effect, induced biofilm formation by S. mutans in a mixed culture with sucrose which was at concentrations less than those required to induce biofilm formation directly...
May 19, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28526785/effects-of-arginine-on-growth-virulence-gene-expression-and-stress-tolerance-by-streptococcus-mutans
#2
Brinta Chakraborty, Robert A Burne
Streptococcus mutans is a common constituent of oral biofilms and a primary etiologic agent of human dental caries. The bacteria associated with dental caries have a potent ability to produce organic acids from dietary carbohydrates and to grow and metabolize in acidic conditions. In contrast, many commensal bacteria produce ammonia through the arginine deiminase system (ADS), which moderates the pH of oral biofilms. Arginine metabolism by the ADS is a significant deterrent to the initiation and progression of dental caries...
May 19, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28526003/the-basic-research-factors-questionnaire-for-studying-early-childhood-caries
#3
Judith Albino, Tamanna Tiwari, Stuart A Gansky, Michelle M Henshaw, Judith C Barker, Angela G Brega, Steven E Gregorich, Brenda Heaton, Terrence S Batliner, Belinda Borrelli, Paul Geltman, Nancy R Kressin, Jane A Weintraub, Tracy L Finlayson, Raul I Garcia
BACKGROUND: We describe development of the Early Childhood Caries (ECC) Basic Research Factors Questionnaire (BRFQ), a battery of measures assessing common potential predictors, mediators, and moderators of ECC. Individual-, family-, and community-level factors that are linked to oral health outcomes across at-risk populations are included. Developing standard measures of factors implicated in ECC has the potential to enhance our ability to understand mechanisms underlying successful prevention and to develop more effective interventions...
May 19, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28523304/optical-coherence-tomography-applications-in-tooth-wear-diagnosis
#4
Veronica MercuŢ, Sanda Mihaela Popescu, Monica Scrieciu, Marina Olimpia Amărăscu, Mihaela Vătu, Oana Andreea Diaconu, Eugen Osiac, Ştefan Mugurel Ghelase
Dental wear represents an irreversible loss of dental hard tissue under the action of physical, chemical and mechanical factors, excluding dental caries and acute trauma. Four clinical forms of dental wear are described: erosion, attrition, abfraction, and abrasion. Most experts agree that in each clinical form multiple etiological factors are involved, one being predominant. Optical coherence tomography (OCT) is a non-invasive optical method characterized by a micronic resolution. The applications of this type of investigation are multiple in the medical field in recent years, and OCT is gaining a growing importance in dentistry...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28521109/cost-effectiveness-of-caries-prevention-in-practice-a-randomized-controlled-trial
#5
C O'Neill, H V Worthington, M Donaldson, S Birch, S Noble, S Killough, L Murphy, M Greer, J Brodison, R Verghis, M Tickle
A 2-arm parallel-group randomized controlled trial measured the cost-effectiveness of caries prevention in caries-free children aged 2 to 3 y attending general practice. The setting was 22 dental practices in Northern Ireland. Participants were centrally randomized into intervention (22,600 ppm fluoride varnish, toothbrush, a 50-mL tube of 1,450 ppm fluoride toothpaste, and standardized prevention advice) and control (advice only), both provided at 6-monthly intervals during a 3-y follow-up. The primary outcome measure was conversion from caries-free to caries-active states assessed by calibrated and blinded examiners; secondary outcome measures included decayed, missing, or filled teeth surfaces (dmfs); pain; and extraction...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28518210/regular-graveyard-in-the-stronghold-versus-settlement-burials-in-the-bailey-comparison-of-early-medieval-populations-from-pohansko-czech-republic
#6
Kateřina Kalová, Renáta Přichystalová, Kateřina Boberová, Alena Pavlůsková
The aim of the study is to identify possible differences in the prevalence of biological stress markers (cribra orbitalia, linear enammel hypoplasia), dental caries, activity markers (Schmorl's nodes) and markers of violence (traumatic lesions) in populations from a typical graveyard around the first church (9(th)-10(th) century AD) in the stronghold and from settlement burials in the southern bailey (second half of the 9(th) - beginning of the 10(th) century AD) of Slavs from Pohansko (Czech Republic). Cribra orbitalia and enamel hypoplasia did not markedly differ in either population...
May 15, 2017: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/28516412/optimization-of-adhesive-pastes-for-dental-caries-prevention
#7
Patteera Sodata, Apa Juntavee, Niwut Juntavee, Jomjai Peerapattana
Dental caries prevention products available on the market contain only remineralizing agents or antibacterial agents. This study aimed to develop adhesive pastes containing calcium phosphate and α-mangostin for dental caries prevention using the optimization technique. Calcium phosphate was used as a remineralizing agent, and extracted α-mangostin was used as an antibacterial agent. The effect of the independent variables, which were fumed silica, Eudragit(®) EPO, polyethylene glycol, and ethyl alcohol, on the responses was investigated...
May 17, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28516265/the-vitamin-d-deficiency-pandemic-approaches-for-diagnosis-treatment-and-prevention
#8
REVIEW
Michael F Holick
Vitamin D deficiency and insufficiency is a global health issue that afflicts more than one billion children and adults worldwide. The consequences of vitamin D deficiency cannot be under estimated. There has been an association of vitamin D deficiency with a myriad of acute and chronic illnesses including preeclampsia, childhood dental caries, periodontitis, autoimmune disorders, infectious diseases, cardiovascular disease, deadly cancers, type 2 diabetes and neurological disorders. This review is to put into perspective the controversy surrounding the definition for vitamin D deficiency and insufficiency as well as providing guidance for how to treat and prevent vitamin D deficiency...
May 17, 2017: Reviews in Endocrine & Metabolic Disorders
https://www.readbyqxmd.com/read/28514517/early-childhood-caries-and-psychological-perceptions-on-child-s-oral-health-increase-the-feeling-of-guilt-in-parents-an-epidemiological-survey
#9
Thiago Saads Carvalho, Jenny Abanto, Elayne Cristina Morais Pinheiro, Adrian Lussi, Marcelo Bönecker
AIM: To assess whether parents feel guilty for their children's oral problems, associating this feeling with socio-economic, demographic, and psychological factors. DESIGN: We included 1313 parent-and-child pairs in this study. The children were 2-4 years old. Parents answered questionnaires on socio-economic and demographic data, and on psychological variables. Sixteen trained dentists (κ > 0.8) examined the children for oral hygiene (the presence and absence of plaque), early childhood caries (ECC; no caries, low and high severity), malocclusion (the presence and absence), and traumatic dental injuries (TDI; the presence and absence)...
May 17, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/28514516/which-factors-most-influence-referral-for-restorative-dental-treatment-under-sedation-and-general-anaesthesia-in-children-with-complex-disabilities-caries-severity-child-functioning-or-dental-service-organisation
#10
Johanna Norderyd, Denise Faulks, Gustavo Molina, Mats Granlund, Gunilla Klingberg
BACKGROUND: The UN Convention on the Rights of the Child gives all children right to the highest standard of services for treatment and rehabilitation. For children with disabilities, sedation and general anaesthesia (GA) are often indicated for dental treatment; however, accessibility to this varies. The International Classification of Functioning, Disability and Health - Child and Youth version (ICF-CY) enables a biopsychosocial description of children undergoing dental treatment. AIM: To investigate conscious sedation and GA in children with complex disabilities and manifest caries and analyse how caries, child functioning, and dental service organisation relate to dental GA (DGA), comparing Argentina, France, and Sweden using the ICF-CY...
May 17, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/28513897/quality-and-survival-of-direct-light-activated-composite-resin-restorations-in-posterior-teeth-a-5-to-20-year-retrospective-longitudinal-study
#11
REVIEW
Ernesto Borgia, Rosario Baron, Jose Luis Borgia
PURPOSE: To analyze the clinical success of direct light-activated composite resin restorations in posterior teeth. The quality of the margins and occlusal surfaces were evaluated, as well as their survival, according to their extensions and locations. The clinical performance of posterior composite resin restorations with different compositions were compared. All restorations were performed by the first author in his private practice, in a 5- to 20-year period. MATERIALS AND METHODS: Several types of composite resins, provided by different manufacturers, were placed in posterior teeth, after isolation with rubber dams...
May 17, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28513096/is-the-oral-fungal-pathogen-candida-albicans-a-cariogen
#12
REVIEW
Daniel Freitas Alves Pereira, Chaminda Jayampath Seneviratne, Cristiane Yumi Koga-Ito, Lakshman Perera Samaranayake
Pathobiology of dental caries is complex. Data from recent molecular microbiologic studies have further redefined the role of the oral microbiome in the etiology of dental caries. This new information challenges the conventional view on the hegemony of classic cariogenic prokaryotes such as Streptococcus mutans in caries aetiology, and raises the intriguing possibility of the participation of the eukaryotic oral fungal pathogen Candida in the caries process. The virulence attributes of Candida species such as their acidogenicity and aciduric nature, the ability to develop profuse biofilms, ferment and assimilate dietary sugars, and produce collagenolytic proteinases are all indicative of their latent cariogenic potential...
May 17, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28512542/cambra-system-in-patients-awaiting-hematopoietic-progenitor-cell-transplant-and-high-caries-risk
#13
Ana Hernández-Fernández, Antonio-José Ortiz-Ruiz, Felipe De Arriba-de la Fuente, Vicente Vicente-García, Pastora Iniesta-López-Matencio, Ricardo-Elias Oñate-Sánchez
BACKGROUND: Recent times have witnessed a significant increase in the number of patients affected by problems related to oncological treatment Aims of this study is to evaluate dental affectation among patients awaiting hematopoietic progenitor cell transplant (HPCT), and they showed high caries risk, so it should establish a protocol prior to transplantation. MATERIAL AND METHODS: The study included 72 patients due for HPCT. Clinical and radiological explorations were performed and oral photos taken...
May 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28512537/decreased-dentin-tubules-density-and-reduced-thickness-of-peritubular-dentin-in-hyperbilirubinemia-related-green-teeth
#14
Rodrigo Neves-Silva, Fabio-Abreu Alves, Alberto Antunes, Mario-Fernando Goes, Marcelo Giannini, Maria-Dânia Tenório, José-Lécio Machado, Adriana-Franco Paes-Leme, Marcio-Ajudarte Lopes, Alan-Roger Santos-Silva
BACKGROUND: It is stated anecdotally that patients with liver diseases in childhood who develop green teeth have increased risk for rampant caries, which may be secondary to changes in dental structure. The aim of this study was to test the hypothesis that hyperbilirubinemia affects the dentin morphology of green teeth. MATERIAL AND METHODS: Sixteen primary teeth were prepared and divided into two groups (green teeth, n = 8 and control, n = 8), which were transversely fractured across the cervical third of the dental crowns; dentin was prepared and sputter-coated with gold, and examined under a scanning electron microscope...
May 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28511604/duplicated-or-hybridized-peptide-functional-domains-promote-oral-homeostasis
#15
T Basiri, N D Johnson, E B Moffa, Y Mulyar, P L Serra Nunes, M A A M Machado, W L Siqueira
Proteins that have existed for millions of years frequently contain repeats of functional domains within their primary structure, thereby improving their functional capacity. In the evolutionary young statherin protein contained within the in vivo-acquired enamel pellicle (AEP), we identified a single functional domain (DR9) located within the protein N-terminal portion that exhibits a higher affinity for hydroxyapatite and more efficient protection against enamel demineralization compared to other native statherin peptides...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28511529/orthodontic-therapy-for-paediatric-cancer-survivors-a-review
#16
REVIEW
Sumita Mishra
The paper aims at reviewing the possibilities of orthodontic therapy for paediatric cancer survivors. It is important to understand the fundamental disease, it's treatment protocols, effects on growing skeleton, dental development, oral cavity and oral mucosa, dental caries, bone, orthodontic tooth movement.
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28511505/effectiveness-of-chewable-tooth-brush-in-children-a-prospective-clinical-study
#17
Lavanya Govindaraju, Deepa Gurunathan
INTRODUCTION: Dental plaque is one of the aetiological factors in causation of dental caries. Effective removal of plaque can reduce the incidence of caries. Various agents for removing plaque has been introduced, of which, chewable brush is a recent advance. There is limited evidence assessing the effectiveness of using chewable brush in children. AIM: The aim of this study was to evaluate the effectiveness of chewable brush in relation to efficiency in plaque removal and reduction in S...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28511504/prevalence-of-distal-caries-in-mandibular-second-molar-due-to-impacted-third-molar
#18
Kamran Bokhari Syed, Fatima Saeed Alshahrani, Wejdan Saad Alabsi, Zainab Ali Alqahtani, Mohammad Shahul Hameed, Abdel Bagi Mustafa, Tanveer Alam
INTRODUCTION: A tooth is said to be impacted if it does not reach the occlusal plane even after two-thirds root formation. The aetiology of impacted teeth is varied and multi-factorial. Significant problems associated with impacted teeth include trismus, infection, cervical caries of second molars. AIM: This study was aimed to assess the prevalence of distal caries in second molar teeth due to impacted third molars and to compare with similar studies conducted elsewhere...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28509567/early-evaluation-of-radiation-induced-parotid-damage-with-diffusion-kurtosis-imaging-a-preliminary-study
#19
Nan Zhou, Weibo Chen, Xia Pan, Jian He, Jing Yan, Zhengyang Zhou, Xiaofeng Yang
Background Radiation-induced parotid gland damage is a common complication of radiotherapy (RT) in patients with nasopharyngeal carcinoma (NPC), which always causes xerostomia, dysphagia, dental caries, and even sleep disorders. Early evaluation of radiation-induced parotid damage is required to facilitate early interventions. Purpose To early-evaluate radiation-induced parotid damage using diffusion kurtosis imaging (DKI) in patients with NPC undergoing RT. Material and Methods Thirty-two patients with NPC underwent DKI for parotid glands pre-RT (two weeks before RT), mid-RT (five weeks after RT began), and post-RT (four weeks after RT)...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28509516/variations-in-survival-time-for-amalgam-and-resin-composite-restorations-a-population-based-cohort-analysis
#20
S Birch, R Price, P Andreou, G Jones, A Portolesi
OBJECTIVE: To estimate the association between the restorative material used and time to further treatment across population cohorts with universal coverage for dental treatment. BASIC RESEARCH DESIGN: Cohort study of variation in survival time for tooth restorations over time and by restoration material used based on an Accelerated Failure Time model. CLINICAL SETTING: Primary dental care clinics. PARTICIPANTS: Members of Canada's First Nations and Inuit population covered by the Non-Insured Health Benefits program of Health Canada for the period April 1, 1999 to March 31, 2012...
September 2016: Community Dental Health
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