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Preterm premature rupture of membrane with perinatal outcome

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https://www.readbyqxmd.com/read/27861554/high-diversity-and-variability-in-the-vaginal-microbiome-in-women-following-preterm-premature-rupture-of-membranes-pprom-a-prospective-cohort-study
#1
Teenus Paramel Jayaprakash, Emily C Wagner, Julie van Schalkwyk, Arianne Y K Albert, Janet E Hill, Deborah M Money
OBJECTIVE: To characterize the vaginal microbiota of women following preterm premature rupture of membranes (PPROM), and determine if microbiome composition predicts latency duration and perinatal outcomes. DESIGN: A prospective cohort study. SETTING: Canada. POPULATION: Women with PPROM between 24+0 and 33+6 weeks gestational age (GA). METHODS: Microbiome profiles, based on pyrosequencing of the cpn60 universal target, were generated from vaginal samples at time of presentation with PPROM, weekly thereafter, and at delivery...
2016: PloS One
https://www.readbyqxmd.com/read/27829004/outcome-at-two-years-of-very-preterm-infants-born-after-rupture-of-membranes-before-viability
#2
Amelie Kieffer, Gaelle Pinto Cardoso, Caroline Thill, Eric Verspyck, Stéphane Marret
PURPOSE: To compare the respiratory and neurological outcomes at two years of age of preterm children born before 33 weeks of gestation (WG) after early preterm premature rupture of membranes (EPPROM) between 14 and 24 WG with preterm children without EPPROM. DESIGN AND PATIENTS: This single-center case-control retrospective study was conducted at Rouen University Hospital between 1st January 2000 and 31st December 2010. All the cases with EPPROM born from 26WG to 32WG were included...
2016: PloS One
https://www.readbyqxmd.com/read/27825282/relationship-between-maternal-c-reactive-protein-level-and-neonatal-outcome-in-patients-with-preterm-premature-rupture-of-membranes-treated-with-ampicillin-and-azithromycin
#3
Mehmet Serdar Kutuk, Osman Bastug, Ahmet Ozdemir, Mehmet Adnan Ozturk, Mahmut Tuncay Ozgun, Mustafa Basbug, Tamer Gunes, Selim Kurtoglu
This historical cohort study aimed to assess the relationship between antenatal maternal C-reactive protein (CRP) level and neonatal outcome preterm premature rupture of membranes (PPROM). We reviewed the records of 70 singleton pregnancies with PPROM between 24 and 34 weeks. Maternal CRP levels of neonates with respiratory distress syndrome, neonatal sepsis, grade 3-4 intraventricular haemorrhage and stage 2-3 necrotizing enterocolitis, perinatal mortality were compared with those without these complications...
August 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27780154/maternal-and-neonatal-outcomes-following-expectant-management-of-preterm-prelabour-rupture-of-membranes-before-viability
#4
Winnie Huiyan Sim, Edward Araujo Júnior, Fabricio Da Silva Costa, Penelope Marie Sheehan
AIM: To assess the contemporary maternal and neonatal outcomes following expectant management of preterm premature rupture of membranes (PPROM) prior to 24 weeks' gestation and to identify prognostic indicators of this morbid presentation. METHODS: We performed a systematic review in the Pubmed and EMBASE databases to identify the primary (perinatal mortality, severe neonatal morbidity and serious maternal morbidity) and secondary (neonatal survival and morbidity) outcomes following expectant management of previable PPROM...
October 25, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27762324/maternal-and-live-birth-outcomes-of-pregnancies-following-assisted-reproductive-technology-a-retrospective-cohort-study
#5
Linling Zhu, Yu Zhang, Yifeng Liu, Runjv Zhang, Yiqing Wu, Yun Huang, Feng Liu, Meigen Li, Saijun Sun, Lanfeng Xing, Yimin Zhu, Yiyi Chen, Li Xu, Liangbi Zhou, Hefeng Huang, Dan Zhang
This study was carried out to explore associations between assisted reproductive technology (ART) and maternal and neonatal outcomes compared with similar outcomes following spontaneously conceived births. We conducted a retrospective cohort study of pregnancies conceived by ART (N = 2641) during 2006-2014 compared to naturally conceived pregnancies (N = 5282) after matching for maternal age and birth year. Pregnancy complications, perinatal complications and neonatal outcomes of enrolled subjects were investigated and analysed by multivariate logistic regression...
October 20, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27744438/vaginal-probiotic-administration-in-the-management-of-preterm-premature-rupture-of-membranes
#6
George J Daskalakis, Alexis K Karambelas
OBJECTIVE: To examine the influence of vaginal probiotic administration as an adjunct to standard antibiotic treatment on perinatal outcome in women with preterm premature rupture of membranes (PPROM). MATERIALS AND METHODS: This was a prospective randomized trial of cases with PPROM (24-34 weeks) that were admitted to our department between 2011 and 2015. Forty-nine cases received vaginal probiotics for 10 days in combination with antibiotic prophylaxis and were compared to 57 others that received only antibiotics for the same time period...
October 15, 2016: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/27661655/practice-bulletin-no-172-premature-rupture-of-membranes
#7
(no author information available yet)
Preterm delivery occurs in approximately 12% of all births in the United States and is a major factor that contributes to perinatal morbidity and mortality (1, 2). Preterm premature rupture of membranes (PROM) complicates approximately 3% of all pregnancies in the United States (3). The optimal approach to clinical assessment and treatment of women with term and preterm PROM remains controversial. Management hinges on knowledge of gestational age and evaluation of the relative risks of delivery versus the risks of expectant management (eg, infection, abruptio placentae, and umbilical cord accident)...
October 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27661647/practice-bulletin-no-172-summary-premature-rupture-of-membranes
#8
(no author information available yet)
Preterm delivery occurs in approximately 12% of all births in the United States and is a major factor that contributes to perinatal morbidity and mortality (1, 2). Preterm premature rupture of membranes (PROM) complicates approximately 3% of all pregnancies in the United States (3). The optimal approach to clinical assessment and treatment of women with term and preterm PROM remains controversial. Management hinges on knowledge of gestational age and evaluation of the relative risks of delivery versus the risks of expectant management (eg, infection, abruptio placentae, and umbilical cord accident)...
October 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27651118/mortality-of-neonatal-respiratory-failure-from-chinese-northwest-nicu-network
#9
L Zhang, Y Qiu, B Yi, L Ni, L Zhang, Pulati Taxi, H Li, Q Zhang, W Wang, Z Liu, L Li, L Zhao, H Wang, B Sun
OBJECTIVES: We aimed to evaluate the efficacy of respiratory support and surfactant in incidence, management and outcome of neonatal hypoxemic respiratory failure (NRF) in Chinese emerging regional neonatal-perinatal care system in the era of universal health insurance policy. STUDY DESIGN: Clinical data of NRF were prospectively collected in 12 consecutive months from 2011 to 2012 in 12 neonatal intensive care units (NICU) in major cities of Northwest China. NRF was defined as hypoxemia requiring nasal continuous positive airway pressure (nCPAP) or intratracheal ventilation combined with surfactant for at least 24 h, with associated risk factors, mortality rate and major co-morbidities analyzed...
October 9, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27620916/adverse-obstetric-outcomes-associated-with-in-vitro-fertilization-in-singleton-pregnancies-a-prospective-cohort-study
#10
Jiabi Qin, Xiaoqi Sheng, Di Wu, Shiyou Gao, Yiping You, Tubao Yang, Hua Wang
OBJECTIVE: To compare the obstetric outcomes of women treated with in vitro fertilization (IVF), women with indicators of subfertility but without assisted reproductive technologies, and fertile women with singleton pregnancies. METHODS: A prospective cohort study was conducted from March 2013 to February 2016 at the Hunan Provincial Maternal and Child Health Hospital in China. Finally, 1260 eligible mothers were recruited into the IVF group, 1899 into the subfertile group, and 2480 into the fertile group...
September 11, 2016: Reproductive Sciences
https://www.readbyqxmd.com/read/27607865/perinatal-outcomes-in-cephalic-compared-with-noncephalic-singleton-presentation-in-the-setting-of-preterm-premature-rupture-of-membranes-before-32-weeks-of-gestation
#11
Lynn M Yee, William A Grobman
OBJECTIVE: To investigate the relationship between fetal presentation at the time of admission for preterm premature rupture of membranes (PROM) and perinatal outcomes, including gestational latency, among women in a large and well-characterized population with preterm PROM at less than 32 weeks of gestation. METHODS: This was a secondary analysis of data from women randomized to receive magnesium sulfate compared with placebo in the previously reported Maternal-Fetal Medicine Units Network Beneficial Effects of Antenatal Magnesium Sulfate (1997-2004) trial...
October 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27567363/nifedipine-versus-placebo-in-the-treatment-of-preterm-prelabor-rupture-of-membranes-a-randomized-controlled-trial-assessment-of-perinatal-outcome-by-use-of-tocolysis-in-early-labor-apostel-iv-trial
#12
Tobias A J Nijman, Elvira O G van Vliet, Christiana A Naaktgeboren, Katrien Oude Rengerink, Thomas S de Lange, Caroline J Bax, Kitty W M Bloemenkamp, Jim van Eyck, Marjolein Kok, Hubertina C J Scheepers, Mallory Woiski, Arie Franx, Ben Willem J Mol, Martijn A Oudijk
OBJECTIVE: Preterm birth is the most common cause of neonatal morbidity and mortality. Around one third of preterm deliveries starts with preterm prelabor rupture of membranes (PPROM). The aim of this trial was to study the effect of prolonged tocolysis with nifedipine versus placebo in women with PPROM on perinatal outcome and prolongation of pregnancy. STUDY DESIGN: The Apostel IV was a nationwide multicenter randomized placebo controlled trial. We included women with PPROM without contractions between 24(+0) and 33(+6) weeks of gestation...
October 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27551580/prophylactic-antibiotics-in-twin-pregnancies-complicated-by-previable-preterm-premature-rupture-of-membranes
#13
Olivia Myrick, Sarah Dotters-Katz, Matthew Grace, Tracy Manuck, Kim Boggess, William Goodnight
OBJECTIVE: This study aims to determine if antibiotics given for latency to women with twins and previable preterm premature rupture of membranes (PPROM) affect the duration from membrane rupture to delivery. METHODS: A retrospective cohort study of twin pregnancies at a single center from 2000 to 2015 with previable (14 (0/7)-22 (6/7) weeks) PPROM was conducted. Women who were not candidates for expectant management or who elected for immediate delivery were excluded...
July 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/27469988/adverse-obstetric-outcomes-after-local-treatment-for-cervical-preinvasive-and-early-invasive-disease-according-to-cone-depth-systematic-review-and-meta-analysis
#14
Maria Kyrgiou, Antonios Athanasiou, Maria Paraskevaidi, Anita Mitra, Ilkka Kalliala, Pierre Martin-Hirsch, Marc Arbyn, Phillip Bennett, Evangelos Paraskevaidis
OBJECTIVE:  To assess the effect of treatment for cervical intraepithelial neoplasia (CIN) on obstetric outcomes and to correlate this with cone depth and comparison group used. DESIGN:  Systematic review and meta-analysis. DATA SOURCES:  CENTRAL, Medline, Embase from 1948 to April 2016 were searched for studies assessing obstetric outcomes in women with or without previous local cervical treatment. DATA EXTRACTION AND SYNTHESIS:  Independent reviewers extracted the data and performed quality assessment using the Newcastle-Ottawa criteria...
2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27384151/sealing-procedures-for-preterm-prelabour-rupture-of-membranes
#15
REVIEW
Adele E Crowley, Rosalie M Grivell, Jodie M Dodd
BACKGROUND: Preterm prelabour rupture of the membranes (PPROM) complicates approximately 2% of pregnancies and can be either spontaneous or iatrogenic in nature. Complications of PPROM include prematurity, chorioamnionitis, neonatal sepsis, limb position defects, respiratory distress syndrome, pulmonary hypoplasia chronic lung disease, periventricular leukomalacia and intraventricular haemorrhage.A number of different sealing techniques have been employed which aim to restore a physical barrier against infection and encourage the re-accumulation of amniotic fluid...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27310552/evaluation-of-perinatal-outcomes-in-pregnant-women-with-preterm-premature-rupture-of-membranes
#16
Alex Sandro Rolland Souza, Adriane Farias Patriota, Gláucia Virgínia de Queiroz Lins Guerra, Brena Carvalho Pinto de Melo
OBJECTIVE: To determine the association between amniotic fluid index (AFI) and perinatal outcomes in preterm premature rupture of membranes (PPROM). METHOD: A retrospective cohort study was conducted between 2008 and 2012. 86 pregnant women were included, with a diagnosis of PPROM and gestational age from 24 to 35 weeks. Women who presented hypertensive disorders, diabetes, fetuses with birth defects and infection at admission were excluded. To determine the association between AFI and perinatal outcomes, chi-square and Fisher's exact test were used if necessary, as well as risk ratio (RR) and 95% confidence intervals (95CI)...
May 2016: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/27243373/clinical-outcomes-after-assisted-reproductive-technology-in-twin-pregnancies-chorionicity-based-comparison
#17
Luming Sun, Gang Zou, Xing Wei, Yan Chen, Jun Zhang, Nanette Okun, Tao Duan
The chorionicity-based evaluation of the perinatal risk in twin pregnancies after assisted reproductive technology (ART) is lacking. A retrospective review was performed of all twin pregnancies monitored prenatally and delivered at our hospital between 2010 and 2014. Chorionicity was diagnosed by ultrasound examination at first trimester and confirmed by postnatal pathology. Pregnancy and perinatal outcomes were prospectively recorded. Adjusted odds ratios (aOR) with 95% confidence intervals (CI) were calculated in a logistic regression model...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27216473/impact-of-fetal-gender-on-the-risk-of-preterm-birth-a-national-cohort-study
#18
Myrthe J C S Peelen, Brenda M Kazemier, Anita C J Ravelli, Christianne J M De Groot, Joris A M Van Der Post, Ben W J Mol, Petra J Hajenius, Marjolein Kok
INTRODUCTION: Fetal gender is associated with preterm birth; however, a proper subdivision by onset of labor and corresponding neonatal outcome by week of gestation is lacking. MATERIAL AND METHODS: Data from the Netherlands Perinatal Registry (1999-2010) were used to calculate relative risk ratios for gender by week of gestation and gender-related risk on adverse neonatal outcomes using a moving average technique. White European women with an alive fetus at onset of labor were included...
September 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27145920/placental-histologic-patterns-and-neonatal-seizure-in-preterm-premature-rupture-of-membrane
#19
Hyun Sun Ko, Ju Young Cheon, Sae Kyung Choi, Hye Won Lee, Ahwon Lee, In Yang Park, Jong Chul Shin
OBJECTIVE: To investigate the relationship between placenta and perinatal outcomes, in preterm infants born to mothers with preterm premature rupture of fetal membrane (PPROM). METHODS: We report detailed histology of placentas and perinatal outcomes of infants from 79 PPROM pregnancies. Placental histologic pattern and adverse perinatal outcomes were assessed by logistic regression, adjusting for gestational age at birth, birth weight and interval from rupture of membrane to delivery...
July 20, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27120475/vaginal-fluid-inflammatory-biomarkers-and-the-risk-of-adverse-neonatal-outcomes-in-women-with-pprom
#20
Nydia Dorfeuille, Valérie Morin, Amélie Tétu, Suzanne Demers, Geneviève Laforest, Katy Gouin, Bruno Piedboeuf, Emmanuel Bujold
Objective The purpose of this study was to evaluate the predictive value of vaginal fluid biomarkers for chorioamnionitis and adverse perinatal outcomes in women with preterm premature rupture of membranes (PPROM). Methods We recruited women with PPROM, without clinical chorioamnionitis, between 22 and 36 weeks' gestation. Vaginal fluid was collected on admission for the measurement of metalloproteinase-8 (MMP-8), interleukin-6 (IL-6), lactate, and glucose concentration. Placental pathology and neonatal charts were reviewed...
August 2016: American Journal of Perinatology
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