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https://www.readbyqxmd.com/read/29684933/-dysphagia-from-a-gastroenterologist-s-perspective
#1
Marcus Hollenbach, Jürgen Feisthammel, Joachim Mössner, Albrecht Hoffmeister
Swallowing disorders (dysphagia) comprise a common cause of medical consultation and are defined as a subjective sensation of difficulty or abnormality of swallowing. In the initial step, a clear differentiation of dysphagia from odynophagia and globus sensation for further diagnostic procedures is mandatory. The careful questioning of patients symptoms and complaints is often helpful for the differentiation of oropharyngeal and esophageal dysphagia. Oropharyngeal dysphagia is mainly caused by neurological disorders (cerebral ischemia, Parkinson's disease, dementia) or local compression of malignancies, thyroid gland or lymph nodes...
May 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29681401/capacity-control-and-responsibility-in-parkinson-s-disease-patients-with-impulse-control-disorders-views-of-neurological-and-psychiatric-experts
#2
Andrew Dawson, Jordie Michael, Ella Dilkes-Frayne, Wayne Hall, Nadeeka N Dissanayaka, Adrian Carter
Dopamine replacement therapy can induce impulse control disorders (ICDs) (e.g., hypersexuality) in susceptible Parkinson's disease patients. ICDs can sometimes result in criminal offending. In a number of past Commonwealth cases, it appears offending ICD patients have been considered to be suffering from 'irresistible impulses' such that their decision-making capacity, behavioural control and responsibility were totally compromised. This contrasts with courts' general scepticism of drug-induced 'compulsion' in cases of addiction-related offending...
April 19, 2018: International Journal of Law and Psychiatry
https://www.readbyqxmd.com/read/29680206/how-do-we-fix-the-shortage-of-neurologists
#3
Adrian Burton
No abstract text is available yet for this article.
April 18, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/29679354/low-serum-phosphate-is-associated-with-ischemic-stroke-in-hemodialysis-patients
#4
Tsang-Shan Chen, Chao-Hung Chen, Chien-An Chen, Li-Ping Chou, Chi-Chu Liu
BACKGROUND: Hemodialysis patients have a high incidence of ischemic stroke. However, the association between serum phosphate levels and ischemic stroke is controversial among hemodialysis patients. The present study is used to evaluate whether serum phosphate levels are associated with ischemic stroke among patients undergoing hemodialysis. METHODS: A total of 84 hemodialysis patients were followed up for 8 years. Data collection included chart reviews and assessments of laboratory records...
April 20, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29678455/different-behavioral-and-pathological-changes-between-epilepsy-associated-depression-and-primary-depression-models
#5
Wei-Feng Peng, Fan Fan, Xin Li, Qian-Qian Zhang, Jing Ding, Xin Wang
PURPOSE: Comorbid depression is common in patients with epilepsy. However, the epilepsy-associated depression is generally atypical and has not been fully recognized by neurologists. This study aimed to compare the behavioral and pathological changes between the chronic lithium chloride-pilocarpine rat epilepsy model (Licl-pilocarpine model) and the Chronic Unpredictable Mild Stress rat depression model (CUMS model), to evaluate for differences between epilepsy-associated depression and primary depression...
April 17, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29677060/cerebral-small-vessel-but-not-large-vessel-disease-is-associated-with-impaired-cerebral-autoregulation-during-cardiopulmonary-bypass-a-retrospective-cohort-study
#6
Yohei Nomura, Roland Faegle, Daijiro Hori, Abbas Al-Qamari, Alexander J Nemeth, Rebecca Gottesman, Gayane Yenokyan, Charles Brown, Charles W Hogue
BACKGROUND: Impaired cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB) is associated with stroke and other adverse outcomes. Large and small arterial stenosis is prevalent in patients undergoing cardiac surgery. We hypothesize that large and/or small vessel cerebral arterial disease is associated with impaired cerebral autoregulation during CPB. METHODS: A retrospective cohort analysis of data from 346 patients undergoing cardiac surgery with CPB enrolled in an ongoing prospectively randomized clinical trial of autoregulation monitoring were evaluated...
April 17, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29673817/combined-outcomes-of-endovascular-or-surgical-treatment-of-unruptured-anterior-communicating-artery-aneurysms-is-a-more-aggressive-management-strategy-warranted
#7
Philip G R Schmalz, Alejandro Enriquez-Marulanda, Abdulrahman Alturki, Christopher J Stapleton, Ajith J Thomas, Christopher S Ogilvy
BACKGROUND: Updated natural history studies suggest anterior communicating artery aneurysms have a higher risk of rupture than formerly appreciated. As endovascular and open techniques advance, morbidity may fall to levels which suggest intervention even for small aneurysms. OBJECTIVE: Assess treatment risk for smaller, unruptured anterior communicating artery aneurysms. METHODS: A cross-sectional study of 149 patients with unruptured anterior communicating aneurysms treated over a six-year period was performed...
April 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29672474/active-epilepsy-and-seizure-control-in-adults-united-states-2013-and-2015
#8
Niu Tian, Michael Boring, Rosemarie Kobau, Matthew M Zack, Janet B Croft
Approximately 3 million American adults reported active epilepsy* in 2015 (1). Active epilepsy, especially when seizures are uncontrolled, poses substantial burdens because of somatic, neurologic, and mental health comorbidity; cognitive and physical dysfunction; side effects of antiseizure medications; higher injury and mortality rates; poorer quality of life; and increased financial cost (2). Thus, prompt diagnosis and seizure control (i.e., seizure-free in the 12 months preceding the survey) confers numerous clinical and social advantages to persons with active epilepsy...
April 20, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29667637/-the-expert-characteristic-of-the-forensic-medical-documentation-for-the-purpose-of-investigations-of-the-injuries-to-the-maxillofacial-region
#9
V L Popov, M O Yagmurov, E L Troshin
The injuries to the maxillofacial region (MFR) are among the most frequently occurring problems encountered if the forensic medical practice. The objective of the present study was the analysis of the quality of the medical record documentation of the victims of the injuries to the maxillofacial region for obtaining the information necessary for forensic medical experts to make the well-founded conclusions. We undertook the in-depth analysis of random samples from the materials stored in the archive of living subjects at the Saint-Petersburg Bureau of forensic medical expertise for the period from 2010 to 2014...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29667151/ethical-and-legal-concerns-with-nevada-s-brain-death-amendments
#10
Greg Yanke, Mohamed Y Rady, Joseph L Verheijde
In early 2017, Nevada amended its Uniform Determination of Death Act (UDDA), in order to clarify the neurologic criteria for the determination of death. The amendments stipulate that a determination of death is a clinical decision that does not require familial consent and that the appropriate standard for determining neurologic death is the American Academy of Neurology's (AAN) guidelines. Once a physician makes such a determination of death, the Nevada amendments require the withdrawal of life-sustaining treatment within twenty-four hours with limited exceptions...
April 17, 2018: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/29666704/practice-patterns-and-barriers-for-intravenous-thrombolysis-a-survey-of-neurologists-in-saudi-arabia
#11
Mohammed H Alanazy, Rima B Barakeh, Alanood Asiri, Maha F Edrees, Ahmad R Abuzinadah, Bandar N Aljafen, Taim Muayqil
Only a small fraction of patients with acute ischemic stroke receive intravenous thrombolysis (IVT). We sought to assess barriers and practice patterns in using IVT for acute ischemic stroke among neurologists in Saudi Arabia. An electronic survey was sent to all neurologists registered with the Saudi Commission for Health Specialties. A total of 148 (77.5%) neurologists responded. The most common reported barriers for IVT administration were delayed presentation to hospitals (82.4%) and unclear time of symptom onset (50...
2018: Neurology Research International
https://www.readbyqxmd.com/read/29664455/physician-awareness-of-decompressive-hemicraniectomy-for-malignant-middle-cerebral-artery-infarction-in-saudi-arabia-and-the-gulf-countries
#12
Hosam M Al-Jehani, Abdulaziz Alsharydah, Seba A Rammal, Saleh S Baeesa, Mohammad Mekhlafi
OBJECTIVE: To explore the perspective on Decompressive craniectomy (DH) of each of these specialties to establish common grounds for improved clinical practice. METHODS: An electronic survey was distributed via email and social media groups to members of these specialties in Kingdom of Saudi Arabia and the Gulf countries. Local practices, common triggers for referral for DH, perceived outcomes of these procedures, individual impression of what constitutes good clinical outcomes were explored...
April 2018: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/29662683/coexistence-of-systemic-lupus-erythematosus-and-multiple-sclerosis-a-case-report-and-literature-review
#13
REVIEW
Elisa Carolina Jácome Sánchez, María Ariana García Castillo, Victor Paredes González, Fernando Guillén López, Edgar Patricio Correa Díaz
Multiple sclerosis (MS) and systemic lupus erythematous (SLE) are autoimmune diseases, the coexistence of which is uncommon in patients. Owing to the rarity of this condition, the distinction between MS and SLE is a diagnostic challenge for neurologists. We present a case report in which MS and SLE were present in the same patient. There are few case reports in the world on the association between MS and SLE. The following case report is the first of its kind in which both MS and SLE are present in a patient from a country with low prevalence of MS such as Ecuador...
April 2018: Multiple Sclerosis Journal—Experimental, Translational and Clinical
https://www.readbyqxmd.com/read/29661694/descriptive-epidemiology-of-parkinsonism-in-the-canton-of-geneva-switzerland
#14
Vanessa Fleury, Pauline Brindel, Nicolas Nicastro, Pierre R Burkhard
OBJECTIVES: A large descriptive cross-sectional population-based prevalence study as well as a retrospective incidence study were undertaken to ascertain the frequency of Parkinson's Disease (PD) and other types of degenerative and non-degenerative parkinsonism in the Canton of Geneva, Switzerland. METHODS: An extensive case-finding approach including records from public hospitals, private neurologists and nursing homes was utilized. All patients with a diagnosis of parkinsonism established between 2003 and 2012 were included...
April 9, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29659394/a-bizarre-bone-scan-of-fibrodysplasia-ossificans-progressiva
#15
Tzyy-Ling Chuang, Kuo-Wei Ho, Yuh-Feng Wang
A 27-year-old woman had progressive bony ankylosis over both hands since she was 5 years old. Bony ankylosing over the peripheral joints and spine slowly progressed, and scoliosis surgery was performed at age 14. Recently, she developed difficulty walking, changing position, and opening her mouth. A neurologist was consulted and ruled out the suspicion of narcolepsy. Chest CT showed ankylosing spondylitis. A bone scan showed a bizarre pattern with radiouptake to the left maxilla, bilateral sacroiliac joints, left middle third femur, and soft tissue uptake over bilateral arms, legs, and pelvis...
April 13, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29657931/evaluation-of-seizure-frequency-distribution-in-epileptic-patients-with-normal-and-abnormal-electroencephalogram-in-al-zahra-hospital-of-isfahan
#16
Mohmmad Reza Najafi, Rokhsareh Meamar, Nafiseh Karimi
Background: Epilepsy is a chronic neurological disorder characterized by seizure recurrence in patients. Electroencephalogram (EEG) has a diagnostic and prognostic role in the management of patients. Studies have shown a significant relation between seizure recurrence and abnormal EEG in newly diagnosed epileptic patients, and people with first episode of unprovoked seizure. The aim of this study is to evaluate seizure frequency in chronic epileptic patients on drug therapy based on normal or abnormal EEG...
2018: Advanced Biomedical Research
https://www.readbyqxmd.com/read/29656001/-fl%C3%A3-neur-neurologique-in-paris-a-guide-to-pinpointing-the-houses-of-famous-neurologists-in-the-late-xix-century
#17
REVIEW
Hélio Afonso Ghizoni Teive, Francisco Manoel Branco Germiniani, Carlos Henrique Ferreira Camargo, Olivier Walusinski, Andrew J Lees
INTRODUCTION: During the last quarter of the XIX century, Paris, France, particularly the Salpêtrière Hospital was the most important centre of reference of Clinical Neurology in the world. The group based on the Salpêtrière Hospital, led by Professor Charcot, who was arguably the most celebrated neurologist in Europe. OBJECTIVE: In this historical review, we present and locate the addresses of the houses of these famous Parisian neurologists from the late XIX century...
April 11, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29655454/an-update-myasthenia-gravis-and-pregnancy
#18
REVIEW
Johanna Hamel, Emma Ciafaloni
Myasthenia gravis presents a risk factor for pregnancy and delivery, and can affect the newborn. In return, pregnancy can affect the course of myasthenia and worsen the disease during pregnancy requiring treatment modifications. Treatment optimization and drug safety should be addressed before conception. Delivery is complicated by prolonged labor. Newborns can develop neonatal myasthenia gravis, a treatable and transient disease. Patients should not be discouraged to become pregnant, but provided with supportive counseling, planning, and monitoring in a multidisciplinary team involving obstetrician, anesthesiologist, pediatrician, and neurologist...
May 2018: Neurologic Clinics
https://www.readbyqxmd.com/read/29652314/-cervical-vertigo-a-neurologist-s-point-of-view
#19
I D Stulin, M V Tardov, N L Kunelskaya, L G Agasarov, A V Boldin
Cervical vertigo (CV) hasn't yet been recognized by many neurologists, as it has no specific clinical symptoms and reliable diagnostic criteria. However, over the past 150 years, there has been accumulated numerous experimental and clinical evidence to support the legitimacy of CV allocation as a separate nosology. This review presents data regarding the vertigo associated with neck pathology: possible evidence of CV existence and the description of its type as well. The principles of CV diagnosis and treatment are considered, an attempt to create a unified concept is proposed...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29652310/-latent-dysphoria-an-instrument-of-screening-and-diagnosis-preliminary-results
#20
M A Morozova, A A Alekseev, G E Rupchev
AIM: Latent dysphoria is a kind of emotional disorder. Its key features are floating feeling of dissatisfaction and irritability accompanied with suppression of expression of these emotions. The article is devoted to the development of a screening diagnostic tool (checklist) to screen and evaluate patients with this emotional problem. MATERIAL AND METHODS: Three hundred and ninety-four neurologists (outpatient segment) were surveyed to assess the prevalence of an emotional disorder that met criteria of latent dysphoria suggested by the authors...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
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