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https://www.readbyqxmd.com/read/29667440/time-use-and-physical-activity-in-a-specialised-brain-injury-rehabilitation-unit-an-observational-study
#1
Leanne Hassett, Siobhan Wong, Emma Sheaves, Maysaa Daher, Andrew Grady, Cara Egan, Carol Seeto, Talia Hosking, Anne Moseley
OBJECTIVES: To determine what is the use of time and physical activity in people undertaking inpatient rehabilitation in a specialised brain injury unit. To determine participants' level of independence related to the use of time and physical activity. METHODS: Design: Cross-sectional observation study. PARTICIPANTS: Fourteen people [mean (SD) age 40 (15) years] with brain injuries undertaking inpatient rehabilitation. PROCEDURE: Participants were observed every 12 minutes over 5 days (Monday to Friday from 7:30 am until 7:30 pm) using a behaviour mapping tool...
April 18, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29608688/oxytetracycline-does-not-cause-growth-promotion-in-finfish
#2
Jesse T Trushenski, Matthew P Aardsma, Kelli J Barry, James D Bowker, Christopher J Jackson, Michelle Jakaitis, Rebecca L McClure, Artur N Rombenso
Until recently, use of antibiotics to enhance terrestrial animal growth performance was a common, U.S. Food and Drug Administration-approved, but controversial practice. There are no FDA-approved production claims for antibiotic drug use in fish, but it is a common misconception that antibiotics are widely used for this purpose in U.S. aquaculture. Antibiotics are not thought to be effective growth promoters in fish, but there is little quantitative data available to address whether there are growth-promoting effects that might incentivize use of antibiotics in this way, despite legal prohibitions...
March 28, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29589458/laparoscopic-treatment-of-bowel-perforation-after-blunt-abdominal-trauma-bat-in-children
#3
P Zahradnikova, J Babala, Ľ Sýkora, J Trnka, M Vidiscak, P Sinka, L Fedorová
Minimally invasive techniques have now become standard for the treatment of many surgical conditions in children. There are a few studies that describe the utility of laparoscopy in BAT in children. In this article, we describe the complete laparoscopic surgical treatment of two patients after a single blunt abdominal trauma, both with bowel perforation. In both cases, the perforation was identified and closed, one laparoscopically with an ongoing suture, the second jejune perforation was closed by laparoscopic-assisted techniques...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/29516486/opioid-induced-likeability-and-feeling-good-are-not-associated-with-return-visits-to-an-ed-among-migraine-patients-administered-iv-hydromorphone
#4
Benjamin W Friedman, Alexander Latev, Caron Campbell, Deborah White
BACKGROUND: Parenteral opioids are used in more than 50% of emergency department (ED) visits for migraine. Use of opioids for migraine has been associated with subsequent ED visits, perhaps because of opioid-induced euphoria. In this study, we quantify the extent to which nontherapeutic effects of opioids influence migraine outcomes. We hypothesized that "feeling good" and medication likeability would in fact be associated with receipt of opioids (rather than relief of migraine pain) and that receipt of opioids (rather than relief of migraine pain) would be associated with return visits to the ED...
March 8, 2018: Headache
https://www.readbyqxmd.com/read/29356844/characteristics-and-management-of-penetrating-abdominal-injuries-in-a-german-level-i-trauma-center
#5
Patrizia Malkomes, Philipp Störmann, Hanan El Youzouri, Sebastian Wutzler, Ingo Marzi, Thomas Vogl, Wolf Otto Bechstein, Nils Habbe
PURPOSE: Penetrating abdominal injuries caused by stabbing or firearms are rare in Germany, thus there is lack of descriptive studies. The management of hemodynamically stable patients is still under dispute. The aim of this study is to review and improve our management of penetrating abdominal injuries. METHODS: We retrospectively reviewed a 10-year period from the Trauma Registry of our level I trauma center. The data of all patients regarding demographics, clinical and outcome parameters were examined...
January 22, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29333425/outcomes-of-selective-surgery-in-patients-with-suspected-small-bowel-injury-from-blunt-trauma
#6
Hyoung-Chul Park, Jong Whan Kim, Min Jeong Kim, Bong Hwa Lee
Purpose: The role of initial conservative therapy with selective surgery for patients with suspected blunt bowel injury by radiologic evaluation is less clear. The aim of the study is to assess the outcomes of patients who received initial conservative therapy with selective delayed surgery, compared to emergency surgery. Methods: During this 8-year study, a total of 77 patients who were hemodynamically stable were enrolled, in which computed tomography verified suspected bowel injury from blunt trauma (mesenteric hematoma, mesenteric fat infiltration, bowel wall thickening, and free fluid without solid organ injury) was managed with either initial conservative therapy with selective delayed surgery (group A; n = 42) or emergency surgery (group B; n = 35)...
January 2018: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29319327/warfarin-dose-adjustment-after-biliopancreatic-diversion-duodenal-switch-bariatric-surgery
#7
Catherine Bolduc, Joëlle Flamand-Villeneuve, Isabelle Giroux, Stéfane Lebel, Serge Simard, Frédéric Picard
BACKGROUND: The absorption of drugs and fat-soluble vitamins is impaired after bariatric surgery on which intestinal length and function are altered. In this context, the anticoagulant effect of warfarin is difficult to predict in the postoperative period. OBJECTIVE: This study aimed at describing the average weekly warfarin dose required to maintain a therapeutic international normalized ratio (INR) before and up to 1 year after sleeve gastrectomy with biliopancreatic diversion and duodenal switch (BPD/DS)...
May 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29302223/the-prescription-opioid-epidemic-a-review-of-qualitative-studies-on-the-progression-from-initial-use-to-abuse
#8
Theodore J Cicero, Matthew S Ellis
Most research designed to answer the "why" of the prescription opioid epidemic has relied on structured interviews, which rigidly attempt to capture the complex reasons people use opioids. In contrast this systematic literature review focuses on peer-reviewed studies that have used a qualitative approach to examine the development of an opioid-use disorder from the point of initial exposure. Rather than simply providing a "high," opioids reportedly relieve psychological/emotional problems or provide an escape from life stressors...
September 2017: Dialogues in Clinical Neuroscience
https://www.readbyqxmd.com/read/29183519/abdominal-trauma-revisited
#9
REVIEW
David V Feliciano
Although abdominal trauma has been described since antiquity, formal laparotomies for trauma were not performed until the 1800s. Even with the introduction of general anesthesia in the United States during the years 1842 to 1846, laparotomies for abdominal trauma were not performed during the Civil War. The first laparotomy for an abdominal gunshot wound in the United States was finally performed in New York City in 1884. An aggressive operative approach to all forms of abdominal trauma till the establishment of formal trauma centers (where data were analyzed) resulted in extraordinarily high rates of nontherapeutic laparotomies from the 1880s to the 1960s...
November 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28918087/left-atrial-enlargement-and-anticoagulation-status-in-patients-with-acute-ischemic-stroke-and-atrial-fibrillation
#10
Katarina Dakay, Andrew D Chang, Morgan Hemendinger, Shawna Cutting, Ryan A McTaggart, Mahesh V Jayaraman, Antony Chu, Nikhil Panda, Christopher Song, Alexander Merkler, Gino Gialdini, Benjamin Kummer, Michael P Lerario, Hooman Kamel, Mitchell S V Elkind, Karen L Furie, Shadi Yaghi
BACKGROUND: Despite anticoagulation therapy, ischemic stroke risk in atrial fibrillation (AF) remains substantial. We hypothesize that left atrial enlargement (LAE) is more prevalent in AF patients admitted with ischemic stroke who are therapeutic, as opposed to nontherapeutic, on anticoagulation. METHODS: We included consecutive patients with AF admitted with ischemic stroke between April 1, 2015, and December 31, 2016. Patients were divided into two groups based on whether they were therapeutic (warfarin with an international normalized ratio ≥ 2...
January 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28915204/laparoscopy-for-trauma-and-the-changes-in-its-use-from-1990-to-2016-a-current-systematic-review-and-meta-analysis
#11
Roberto Cirocchi, Arianna Birindelli, Kenji Inaba, Matteo Mandrioli, Alice Piccinini, Renata Tabola, Luigi Carlini, Gregorio Tugnoli, Salomone Di Saverio
BACKGROUND: The role of laparoscopy in the diagnosis and treatment of stable abdominal trauma patients is still a matter of serious debate and only incomplete data are available. MATERIALS AND METHODS: We performed a systematic review and meta-analysis of the literature between January 1990 and August 2016. RESULTS: Overall, 9817 laparoscopies were performed for abdominal trauma; only 26.2% of the cases were converted to a laparotomy. The incidence of therapeutic laparotomies showed a reduction from 69% to 47...
September 14, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28870818/-fatal-female-genital-mutilation-in-a-10-year-old-girl
#12
A Sow, G Diagne, Y Keita, O Sow, A Ndiath, A Ouattara, M-L Sarr, A Sylla, C Moreira
Female genital mutilation (FGM) comprises all procedures involving partial or total removal of the external genitalia and/or any other procedures affecting the female genitalia, for cultural or religious reasons or for nontherapeutic purposes in general. FGM is responsible for a number of short-, medium-, and long-term complications that can engage the vital and functional prognosis, especially in African countries. We report on a case in a 10-year-old girl who underwent genital mutilation, a traditional type of total excision during the neonatal period...
September 1, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28846521/nontherapeutic-circumcision-of-minors-as-an-ethically-problematic-form-of-iatrogenic-injury
#13
J Steven Svoboda
Nontherapeutic circumcision (NTC) of male infants and boys is a common but misunderstood form of iatrogenic injury that causes harm by removing functional tissue that has known erogenous, protective, and immunological properties, regardless of whether the surgery generates complications. I argue that the loss of the foreskin itself should be counted, clinically and morally, as a harm in evaluating NTC; that a comparison of benefits and risks is not ethically sufficient in an analysis of a nontherapeutic procedure performed on patients unable to provide informed consent; and that circumcision violates clinicians' imperatives to respect patients' autonomy, to do good, to do no harm, and to be just...
August 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28831812/thromboembolic-and-major-bleeding-events-with-rivaroxaban-versus-warfarin-use-in-a-real-world-setting
#14
Giavanna Russo-Alvarez, Kathryn A Martinez, Megan Valente, James Bena, Bo Hu, Jennifer Luxenburg, Alexander Chaitoff, Catherine Ituarte, Andrei Brateanu, Michael B Rothberg
BACKGROUND: Although randomized trials demonstrate the noninferiority of rivaroxaban compared with warfarin in the context of nonvalvular atrial fibrillation (AF), little is known about how these drugs compare in practice. OBJECTIVE: To assess the relative effectiveness and safety of rivaroxaban versus warfarin in a large health system and to evaluate this association by time in therapeutic range (TTR). METHODS: We conducted a retrospective cohort study with propensity matching in the Cleveland Clinic Health System...
January 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28749780/the-prevalence-of-extended-spectrum-beta-lactamase-producing-multidrug-resistant-escherichia-coli-in-poultry-chickens-and-variation-according-to-farming-practices-in-punjab-india
#15
Charles H Brower, Siddhartha Mandal, Shivdeep Hayer, Mandeep Sran, Asima Zehra, Sunny J Patel, Ravneet Kaur, Leena Chatterjee, Savita Mishra, B R Das, Parminder Singh, Randhir Singh, J P S Gill, Ramanan Laxminarayan
BACKGROUND: Agricultural use of antimicrobials in subtherapeutic concentrations is increasing in response to the rising demand for food animal products worldwide. In India, the use of antimicrobials in food animal production is unregulated. Research suggests that many clinically important antimicrobials are used indiscriminately. This is the largest study to date in India that surveys poultry production to test for antimicrobial resistance and the occurrence of extended-spectrum β-lactamases (ESBLs) modulated by farming and managerial practices...
July 20, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28689604/outcomes-of-hospitalized-patients-undergoing-emergency-general-surgery-remote-from-admission
#16
COMPARATIVE STUDY
Catherine E Sharoky, Elizabeth A Bailey, Morgan M Sellers, Elinore J Kaufman, Andrew J Sinnamon, Christopher J Wirtalla, Daniel N Holena, Rachel R Kelz
BACKGROUND: Emergency general surgery during hospitalization has not been well characterized. We examined emergency operations remote from admission to identify predictors of postoperative 30-day mortality, postoperative duration of stay >30 days, and complications. METHODS: Patients >18 years in The American College of Surgeons National Surgical Quality Improvement Program (2011-2014) who had 1 of 7 emergency operations between hospital day 3-18 were included...
September 2017: Surgery
https://www.readbyqxmd.com/read/28446999/minimally-invasive-staging-of-esophageal-cancer
#17
REVIEW
Kunal Mehta, Valentino Bianco, Omar Awais, James D Luketich, Arjun Pennathur
Esophageal cancer is one of the most common malignancies in the world today and the sixth-leading cause of cancer-related mortality. Accurate preoperative staging of esophageal cancer is imperative to the selection of appropriate treatments. Patients with esophageal carcinomas typically undergo a multimodality staging process including noninvasive imaging techniques, such as computed tomography (CT) and positron emission tomography (PET), as well as endoscopic ultrasound (EUS), which is slightly more invasive...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28438704/folic-acid-decorated-polyamidoamine-dendrimer-exhibits-high-tumor-uptake-and-sustained-highly-localized-retention-in-solid-tumors-its-utility-for-local-sirna-delivery
#18
Leyuan Xu, W Andrew Yeudall, Hu Yang
The utility of folic acid (FA)-decorated polyamidoamine dendrimer G4 (G4-FA) as a vector was investigated for local delivery of siRNA. In a xenograft HN12 (or HN12-YFP) tumor mouse model of head and neck squamous cell carcinomas (HNSCC), intratumorally (i.t.) injected G4-FA exhibited high tumor uptake and sustained highly localized retention in the tumors according to near infrared (NIR) imaging assessment. siRNA against vascular endothelial growth factor A (siVEGFA) was chosen as a therapeutic modality. Compared to the nontherapeutic treatment groups (PBS solution or dendrimer complexed with nontherapeutic siRNA against green fluorescent protein (siGFP)), G4-FA/siVEGFA showed tumor inhibition effects in single-dose and two-dose regimen studies...
July 15, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28390650/garlic-burn-of-the-oral-mucosa-a-case-report-and-review-of-self-treatment-chemical-burns
#19
Richard J Vargo, Blake M Warner, Anitha Potluri, Joanne L Prasad
BACKGROUND AND OVERVIEW: Inappropriate self-treatment with topically applied therapeutic or nontherapeutic agents frequently results in mucosal burns. Although such chemical burns typically are associated with misuse of analgesics, investigators also have reported them in conjunction with topical application of a variety of other agents. CASE DESCRIPTION: The authors report an unusual case of a 49-year-old man seeking care for maxillary tooth pain who had an oral mucosal burn of the maxillary vestibule caused by topical application of crushed raw garlic...
April 5, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28382255/angioembolization-is-necessary-with-any-volume-of-contrast-extravasation-in-blunt-trauma
#20
Ankur Bhakta, David S Magee, Matthew S Peterson, Michael Shay O'Mara
INTRODUCTION: Reduction of nonessential angiogram and embolization for patients sustaining blunt abdominal and pelvic trauma would allow improved utilization and decreased morbidity related to nontherapeutic embolization. We hypothesized that the nature of intravenous contrast extravasation (IVCE) on computed tomography (CT) would be directly related to the finding of extravasation on angiogram and need for embolization. METHODS: A 5-year retrospective evaluation of trauma patients with IVCE on CT...
January 2017: International Journal of Critical Illness and Injury Science
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