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Auditory Brainstem Implant

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https://www.readbyqxmd.com/read/29877144/peri-operative-electrically-evoked-auditory-brainstem-response-assessment-of-facial-nerve-cochlea-interaction-at-cochlear-implantation
#1
Nadine Schart-Morén, Karin Hallin, Sumit K Agrawal, Hanif M Ladak, Per-Olof Eriksson, Hao Li, Helge Rask-Andersen
OBJECTIVES: Dehiscence between the cochlear otic capsule and the facial nerve canal is a rare and relatively newly described pathology. In cochlear implantation (CI), this dehiscence may lead to adverse electric facial nerve stimulation (FNS) already at low levels, rendering its use impossible. Here, we describe an assessment technique to foresee this complication. METHODS: Pre- and postoperative computed tomography (CT) scans and intraoperative electrically evoked auditory brainstem response (e-ABR) measurements were analyzed in two patients with cochlear-facial dehiscence (CFD)...
June 7, 2018: Cochlear Implants International
https://www.readbyqxmd.com/read/29860618/the-transplantation-of-hbm-mscs-increases-bone-neo-formation-and-preserves-hearing-function-in-the-treatment-of-temporal-bone-defects-on-the-experience-of-two-month-follow-up
#2
Lukáš Školoudík, Viktor Chrobok, Zuzana Kočí, Jiří Popelář, Josef Syka, Jan Laco, Alžběta Filipová, Eva Syková, Stanislav Filip
Temporal bone reconstruction is a persisting problem following middle ear cholesteatoma surgery. Seeking to advance the clinical transfer of stem cell therapy we attempted the reconstruction of temporal bone using a composite bioartificial graft based on a hydroxyapatite bone scaffold combined with human bone marrow-derived mesenchymal stromal cells (hBM-MSCs). The aim of this study was to evaluate the effect of the combined biomaterial on the healing of postoperative temporal bone defects and the preservation of physiological hearing functions in a guinea pig model...
June 3, 2018: Stem Cell Reviews
https://www.readbyqxmd.com/read/29798293/-experimental-observation-on-the-effect-of-bone-marrow-mesenchymal-stem-cells-transplanting-cxcr4-over-gentamicin-ototoxicity
#3
S P Huang, X Y Wang, C Fang, X Y Wang, Q Wu
Objective: To observe the survival and migration ability of CXCR4-BMSCs in guinea pig cochlea with gentamycin induced sensorineural hearing loss, and to explore whether SDF-1/CXCR4 axis can mediate bone marrow mesenchymal stem cells (BMSCs) to cochlear homing. Method: BMSCs were isolated and extracted from guinea pigs. A bone marrow mesenchymal stem cell line with overexpression of CXCR4 was established. The animal model of sensorineural deafness was established by intraperitoneal injection of gentamicin[100 mg/(kg·d)]in 50 healthy guinea pigs...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29798175/-triple-semicircular-canal-occlusion-with-cochlear-implantation-for-delayed-endolymphatic-hydrops-a-case-report
#4
L B Cai, J Yang
A 46-year-old female with profound sensorineural hearing loss in her left ear from childhood developed tinnitus and fluctuating hearing loss on the right side 8 years ago. Four years later, paroxysmal episodes of rotatory vertigo occurred with gradually increased frequency, lasting from half an hour to 2 hours and accompanied with nausea and vomiting. Audiometric test revealed severe sensorineural hearing loss in both of her ears. The tympanograms showed type A on both sides. The threshold of auditory brainstem response was 97 dBnHL in her right ear while no waves could be educed on her left side...
July 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29794459/hearing-rehabilitation-in-neurofibromatosis-type-2
#5
Hannah J D North, Simon K W Lloyd
Bilateral vestibular schwannomas are almost pathognomonic of neurofibromatosis type 2 (NF2). As a result of these tumors, hearing loss is the presenting symptom in 60% of adults and 30% of children with NF2. It is often bilateral. The best means of preserving hearing in patients with NF2 is conservative management. Even so at least 28% of patients have progression of hearing loss following diagnosis. The likelihood of progression of hearing loss is, at least in part, determined by the type of mutation. Treatment of vestibular schwannomas often has a detrimental effect on hearing...
2018: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29794457/management-of-cochlear-nerve-hypoplasia-and-aplasia
#6
Simon R Freeman, Levent Sennaroglu
Approximately 2% of congenital profound deafness cases are due to cochlear nerve (CN) deficiency. MRI is essential to confirm if the nerve is deficient, but because of limitations with resolution, especially when the internal auditory canal is narrowed, it is often unable to distinguish between hypoplasia and aplasia. A full audiometric test battery should always be performed, even if the MRI suggests CN aplasia, as there will sometimes be evidence of audition. Electrically evoked auditory brainstem response testing can be carried out transtympanically via the round window or using an intracochlear test electrode to help determine the status of the CN...
2018: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29794451/intraoperative-auditory-system-monitoring
#7
Hidemi Miyazaki, Per Caye-Thomasen
A new electrophysiological system for intraoperative, continuous, near-real time monitoring of cochlear nerve function through acoustic stimulation in the ear canal and recording of the evoked dorsal cochlear nucleus potentials (DNAPs) by a specially designed DNAP electrode placed directly on the brainstem is described. The system is denominated "(cerebellopontine angle) CPA Master" and is designed for hearing preservation surgery in the cerebello-pontine angle, through the retro-sigmoid or the retro-labyrinthine approach...
2018: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29754738/psychological-follow-up-care-of-neurofibromatosis-type-2-patients-and-their-relatives
#8
REVIEW
C Carillo, M Kiening, S Bergheimer, M Kalamarides
Neurofibromatosis type 2 (NF2) confronts patients and their relatives with the dual issue of a progressive disease and disability. Deafness creates a brutal rupture in the patients' course of life, and other disabilities often follow in addition, that further deteriorates their quality of life. Hearing rehabilitation, via a cochlear implant and auditory brainstem implant, attempts to reduce the feeling of isolation and suffering due to communication impairment. A NF2-specific quality of life questionnaire not only helps to evaluate the impact of the disease but it is also useful therapy proposals (treatment, auditory implants)...
May 10, 2018: Neuro-Chirurgie
https://www.readbyqxmd.com/read/29744729/supra-threshold-hearing-and-fluctuation-profiles-implications-for-sensorineural-and-hidden-hearing-loss
#9
REVIEW
Laurel H Carney
An important topic in contemporary auditory science is supra-threshold hearing. Difficulty hearing at conversational speech levels in background noise has long been recognized as a problem of sensorineural hearing loss, including that associated with aging (presbyacusis). Such difficulty in listeners with normal thresholds has received more attention recently, especially associated with descriptions of synaptopathy, the loss of auditory nerve (AN) fibers as a result of noise exposure or aging. Synaptopathy has been reported to cause a disproportionate loss of low- and medium-spontaneous rate (L/MSR) AN fibers...
May 9, 2018: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/29718280/early-communication-development-of-children-with-auditory-brainstem-implants
#10
Laurie S Eisenberg, Dianne Hammes Ganguly, Amy S Martinez, Laurel M Fisher, Margaret E Winter, Jamie L Glater, Debra K Schrader, Janice Loggins, Eric P Wilkinson
The auditory brainstem implant (ABI) is an auditory sensory device that is surgically placed on the cochlear nucleus of the brainstem for individuals who are deaf but unable to benefit from a cochlear implant (CI) due to anatomical abnormalities of the cochlea and/or eighth nerve, specific disease processes, or temporal bone fractures. In the United States, the Food and Drug Administration has authorized a Phase I clinical trial to determine safety and feasibility of the ABI in up to 10 eligible young children who are deaf and either derived no benefit from the CI or were anatomically unable to receive a CI...
April 26, 2018: Journal of Deaf Studies and Deaf Education
https://www.readbyqxmd.com/read/29672320/correlation-between-preoperative-auditory-steady-state-response-and-postoperative-electrically-evoked-auditory-brainstem-response-and-t-level-in-cochlear-implantation-for-child-patients-with-inner-ear-malformations
#11
Xiao-Feng Qiao, Xin Li, Dong Wang, Tong-Li Li
OBJECTIVE: This study aims to investigate the correlation between thresholds of preoperative multiple auditory steady-state response (ASSR) and electrically evoked auditory brainstem response (EABR) and the behavioral threshold. METHODS: A total of 72 patients were elected to receive a multichannel cochlear implant. According to the residual hearing determined in a preoperative test using high-, moderate-, and low-frequency ASSR, these patients were divided into the following 2 groups: residual hearing and hearing loss...
2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29608482/posterior-fossa-re-exploration-for-recurrent-trigeminal-neuralgia-operative-findings-and-surgical-techniques
#12
Bao-Hui Feng, Xu-Hui Wang, Shi-Ting Li
OBJECTIVE: Microvascular decompression (MVD) is considered the first choice for the surgical treatment of trigeminal neuralgia (TN). However, recurrence after MVD is still a problem and a challenge for neurosurgeons. In this study, we share our experience in the posterior fossa re-exploration of the recurrent cases. METHODS: From January 2014 to January 2015, 15 recurrent TN patients who received fossa re-exploration were retrospectively studied. Surgeries were performed by retrosigmoid suboccipital approach...
March 30, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29607748/auditory-brainstem-implant-in-postmeningitis-totally-ossified-cochleae
#13
Andréa Felice Dos Santos Malerbi, Maria Valéria Schmidt Goffi-Gomez, Robinson Koji Tsuji, Marcos de Queiroz Teles Gomes, Rubens de Brito Neto, Ricardo Ferreira Bento
INTRODUCTION: An auditory brainstem implant (ABI) is an option for auditory rehabilitation in patients with totally ossified cochleae who cannot receive a conventional cochlear implant. OBJECTIVE: To evaluate the outcomes in audiometry and speech perception tests after the implantation of an ABI via the extended retrolabyrinthine approach in patients with postmeningitis hearing loss. MATERIALS AND METHODS: Ten patients, including children and adults, with postmeningitis hearing loss and bilateral totally ossified cochleae received an ABI in a tertiary center from 2009 to 2015...
April 1, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29573880/responses-of-neurons-in-the-feline-inferior-colliculus-to-modulated-electrical-stimuli-applied-on-and-within-the-ventral-cochlear-nucleus-implications-for-an-advanced-auditory-brainstem-implant
#14
Douglas McCreery, Kamal Yadev, Martin Han
Auditory brainstem implants (ABIs) can restore useful hearing to persons with deafness who cannot benefit from cochlear implants. However, the quality of hearing restored by ABIs rarely is comparable to that provided by cochlear implants in persons for whom those are appropriate. In an animal model, we evaluated elements of a prototype of an ABI in which the functions of macroelectrodes on the surface of the dorsal cochlear nucleus would be integrated with the function of multiple penetrating microelectrodes implanted into the ventral cochlear nucleus...
June 2018: Hearing Research
https://www.readbyqxmd.com/read/29573425/cochlear-implantation-and-auditory-brainstem-implantation-in-neurofibromatosis-type-2
#15
Kevin A Peng, Mark B Lorenz, Steven R Otto, Derald E Brackmann, Eric P Wilkinson
OBJECTIVES/HYPOTHESIS: To report a series of patients with neurofibromatosis type 2 (NF2), where each patient underwent both cochlear implantation and auditory brainstem implantation for hearing rehabilitation, and to discuss factors influencing respective implant success. STUDY DESIGN: Retrospective case series. METHODS: Ten NF2 patients with both cochlear implantations and auditory brainstem implantations were retrospectively reviewed. Speech testing for auditory brainstem implants (ABIs) and cochlear implants (CIs) was performed separately...
March 24, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29557843/a-xenograft-model-of-vestibular-schwannoma-and-hearing-loss
#16
Christine T Dinh, Olena Bracho, Christine Mei, Esperanza Bas, Cristina Fernandez-Valle, Fred Telischi, Xue-Zhong Liu
HYPOTHESIS: Microsurgical implantation of mouse merlin-deficient Schwann cells (MD-SC) into the cerebellopontine angle of immunodeficient rats will initiate tumor formation, hearing loss, and vestibular dysfunction. BACKGROUND: The progress in identifying effective drug therapies for treatment of Neurofibromatosis type II (NF2) is limited by the availability of animal models of VS that develop hearing loss and imbalance. METHODS: A microsurgical technique for implanting MD-SCs onto the cochleovestibular nerve of rats was developed...
June 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29553844/estimation-of-the-status-of-spiral-ganglion-neurons-and-schwann-cells-in-the-auditory-neural-degeneration-mouse-using-the-auditory-brainstem-response
#17
Zhi-Jian Zhang, Hong-Xia Guan, Kun Yang, Bo-Kui Xiao, Hua Liao, Yang Jiang, Tao Zhou, Qing-Quan Hua
CONCLUSION: The auditory brainstem response (ABR) wave I threshold, latency and amplitude are insensitive to spiral ganglion neurons (SGNs) degeneration, but are sensitive to the degeneration of Schwann cells and can estimate the status of Schwann cells in a neural degeneration mouse model. The thorough pre-operative ABR assessment would be helpful in predicting cochlear implant performance. OBJECTIVES: This study aimed in finding a non-invasive electrophysiological method to evaluate the status of the auditory nerve and the Schwann cells in sensorineural hearing loss (SNHL) and auditory neuropathy (AN) ears, and providing useful information for candidates screening and outcome prediction in cochlear implantation...
July 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29551308/auditory-perceptual-learning-and-changes-in-the-conceptualization-of-auditory-cortex
#18
REVIEW
Dexter R F Irvine
Perceptual learning, improvement in discriminative ability as a consequence of training, is one of the forms of sensory system plasticity that has driven profound changes in our conceptualization of sensory cortical function. Psychophysical and neurophysiological studies of auditory perceptual learning have indicated that the characteristics of the learning, and by implication the nature of the underlying neural changes, are highly task specific. Some studies in animals have indicated that recruitment of neurons to the population responding to the training stimuli, and hence an increase in the so-called cortical "area of representation" of those stimuli, is the substrate of improved performance, but such changes have not been observed in other studies...
March 12, 2018: Hearing Research
https://www.readbyqxmd.com/read/29537890/evaluating-auditory-pathway-by-electrical-auditory-middle-latency-response-and-postoperative-hearing-rehabilitation
#19
Bin Wang, Keli Cao, Chaogang Wei, Zhiqiang Gao, Huan Li
OBJECTIVE: To establish an effective detection method to evaluate auditory pathway in patients by electrical evoked middle latency response (EMLR) before artificial cochlear implantation, and to analyze the relationship between postoperative hearing rehabilitation and auditory cortex functions. METHODS: Twenty-three patients with artificial cochlear implant were recruited. EMLR was measured after adjusting the depth of anesthesia. The electrical auditory brainstem response (EABR) mode with monopolar stimulation and two-phase alternating current square waves was selected...
March 14, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29494474/hearing-restoration-in-cochlear-nerve-deficiency-the-choice-between-cochlear-implant-or-auditory-brainstem-implant-a-meta-analysis
#20
Annemarie Vesseur, Rolien Free, Chantal Snels, Friedo Dekker, Emmanuel Mylanus, Berit Verbist, Johan Frijns
OBJECTIVE: To answer the dilemma clinician's face when deciding between cochlear implant (CI) and auditory brainstem implant (ABI) treatment options in patients with cochlear nerve deficiency (CND). STUDY DESIGN: Case study supplemented with literature review and meta-analysis. SETTING: Tertiary referral center. PATIENT(S): Child with CHARGE syndrome and congenital deafness. INTERVENTION(S): ABI as there was no benefit after bilateral cochlear implantation...
April 2018: Otology & Neurotology
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