keyword
MENU ▼
Read by QxMD icon Read
search

Respiratory microbiota

keyword
https://www.readbyqxmd.com/read/28342288/the-role-of-acute-and-chronic-respiratory-colonization-and-infections-in-the-pathogenesis-of-copd
#1
REVIEW
Janice M Leung, Pei Yee Tiew, Micheál Mac Aogáin, Kurtis F Budden, Valerie Fei Lee Yong, Sangeeta S Thomas, Kevin Pethe, Philip M Hansbro, Sanjay H Chotirmall
COPD is a major global concern, increasingly so in the context of ageing populations. The role of infections in disease pathogenesis and progression is known to be important, yet the mechanisms involved remain to be fully elucidated. While COPD pathogens such as Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae are strongly associated with acute exacerbations of COPD (AECOPD), the clinical relevance of these pathogens in stable COPD patients remains unclear. Immune responses in stable and colonized COPD patients are comparable to those detected in AECOPD, supporting a role for chronic colonization in COPD pathogenesis through perpetuation of deleterious immune responses...
March 25, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28341851/respiratory-microbiome-of-endangered-southern-resident-killer-whales-and-microbiota-of-surrounding-sea-surface-microlayer-in-the-eastern-north-pacific
#2
Stephen A Raverty, Linda D Rhodes, Erin Zabek, Azad Eshghi, Caroline E Cameron, M Bradley Hanson, J Pete Schroeder
In the Salish Sea, the endangered Southern Resident Killer Whale (SRKW) is a high trophic indicator of ecosystem health. Three major threats have been identified for this population: reduced prey availability, anthropogenic contaminants, and marine vessel disturbances. These perturbations can culminate in significant morbidity and mortality, usually associated with secondary infections that have a predilection to the respiratory system. To characterize the composition of the respiratory microbiota and identify recognized pathogens of SRKW, exhaled breath samples were collected between 2006-2009 and analyzed for bacteria, fungi and viruses using (1) culture-dependent, targeted PCR-based methodologies and (2) taxonomically broad, non-culture dependent PCR-based methodologies...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28337489/antibiotic-resistance-profiling-and-microbiota-of-the-upper-respiratory-tract-of-apparently-healthy-dogs-in-ibadan-south-west-nigeria
#3
Oluwafemi Babatunde Daodu, Elizabeth Adesola Amosun, Daniel Oladimeji Oluwayelu
BACKGROUND: Rearing of dogs and other pets has become increasingly popular in modern society. Bacterial flora resides within the nasal and oral cavities of dogs and when chanced, can be pathogenic. Certain similarities between humans and dogs portends dangerous behavioral habits that could lead to zoonotic disease transmission. This study was aimed at isolation, identification and antibiotic profiling of bacteria from nasal swabs of apparently healthy dogs. The zoonotic risk was also considered...
2017: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28330466/the-nasopharyngeal-microbiota-of-beef-cattle-before-and-after-transport-to-a-feedlot
#4
Devin B Holman, Edouard Timsit, Samat Amat, D Wade Abbott, Andre G Buret, Trevor W Alexander
BACKGROUND: The nasopharyngeal (NP) microbiota plays an important role in bovine health, comprising a rich and diverse microbial community. The nasopharynx is also the niche for potentially pathogenic agents which are associated with bovine respiratory disease (BRD), a serious and costly illness in feedlot cattle. We used 14 beef heifers from a closed and disease-free herd to assess the dynamics of the NP microbiota of cattle that are transported to a feedlot. Cattle were sampled prior to transport to the feedlot (day 0) and at days 2, 7, and 14...
March 22, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28316330/the-microbiota-of-the-respiratory-tract-gatekeeper-to-respiratory-health
#5
REVIEW
Wing Ho Man, Wouter A A de Steenhuijsen Piters, Debby Bogaert
The respiratory tract is a complex organ system that is responsible for the exchange of oxygen and carbon dioxide. The human respiratory tract spans from the nostrils to the lung alveoli and is inhabited by niche-specific communities of bacteria. The microbiota of the respiratory tract probably acts as a gatekeeper that provides resistance to colonization by respiratory pathogens. The respiratory microbiota might also be involved in the maturation and maintenance of homeostasis of respiratory physiology and immunity...
March 20, 2017: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/28303121/identification-of-lama-glama-as-reservoirs-for-acinetobacter-lwoffii
#6
Martín M Ledesma, Ailén M Díaz, Claudia Barberis, Carlos Vay, Marcela A Manghi, Juliana Leoni, Marisa S Castro, Alejandro Ferrari
South American Camelids have an increasing relevance in local economies, worldwide. These animals are bred for their meat, fur and as companion and therapy animals. Thus, their sanitary status should be well-established. According to the OIE (World Organization for Animal Health), respiratory infections mainly produced by Pasteurella spp. have been reported for camelids. It has been stated that this microorganism causes a mild disease, although many authors report it is an important cause of mortality among alpacas...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28293681/community-level-differences-in-the-microbiome-of-healthy-wild-mallards-and-those-infected-by-influenza-a-viruses
#7
Holly H Ganz, Ladan Doroud, Alana J Firl, Sarah M Hird, Jonathan A Eisen, Walter M Boyce
Waterfowl, especially ducks and geese, are primary reservoirs for influenza A viruses (IAVs) that evolve and emerge as important pathogens in domestic animals and humans. In contrast to humans, where IAVs infect the respiratory tract and cause significant morbidity and mortality, IAVs infect the gastrointestinal tract of waterfowl and cause little or no pathology and are spread by fecal-oral transmission. For this reason, we examined whether IAV infection is associated with differences in the cloacal microbiome of mallards (Anas platyrhyncos), an important host of IAVs in North America and Eurasia...
January 2017: MSystems
https://www.readbyqxmd.com/read/28278278/dynamic-changes-of-the-respiratory-microbiota-and-its-relationship-to-fecal-and-blood-microbiota-in-healthy-young-cats
#8
Aida I Vientós-Plotts, Aaron C Ericsson, Hansjorg Rindt, Megan E Grobman, Amber Graham, Kaitlin Bishop, Leah A Cohn, Carol R Reinero
Advances in the field of metagenomics using culture-independent methods of microbial identification have allowed characterization of rich and diverse communities of bacteria in the lungs of healthy humans, mice, dogs, sheep and pigs. These data challenge the long held belief that the lungs are sterile and microbial colonization is synonymous with pathology. Studies in humans and animals demonstrate differences in the composition of airway microbiota in health versus disease suggesting respiratory dysbiosis occurs...
2017: PloS One
https://www.readbyqxmd.com/read/28261214/the-influence-of-the-microbiome-on-early-life-severe-viral-lower-respiratory-infections-and-asthma-food-for-thought
#9
REVIEW
Jason P Lynch, Md Al Amin Sikder, Bodie F Curren, Rhiannon B Werder, Jennifer Simpson, Páraic Ó Cuív, Paul G Dennis, Mark L Everard, Simon Phipps
Severe viral lower respiratory infections are a major cause of infant morbidity. In developing countries, respiratory syncytial virus (RSV)-bronchiolitis induces significant mortality, whereas in developed nations the disease represents a major risk factor for subsequent asthma. Susceptibility to severe RSV-bronchiolitis is governed by gene-environmental interactions that affect the host response to RSV infection. Emerging evidence suggests that the excessive inflammatory response and ensuing immunopathology, typically as a consequence of insufficient immunoregulation, leads to long-term changes in immune cells and structural cells that render the host susceptible to subsequent environmental incursions...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28231472/effects-of-nasal-instillation-of-a-nitric-oxide-releasing-solution-or-parenteral-administration-of-tilmicosin-on-the-nasopharyngeal-microbiota-of-beef-feedlot-cattle-at-high-risk-of-developing-respiratory-tract-disease
#10
E Timsit, M Workentine, T Crepieux, C Miller, G Regev-Shoshani, A Schaefer, T Alexander
Nitric oxide has bactericidal and virucidal properties. Nasal instillation of a nitric oxide releasing solution (NORS) on arrival at the feedlot was recently reported as inferior to a parenteral injection of tilmicosin (macrolide antibiotic) for control of bovine respiratory disease (BRD) in cattle at high-risk of developing BRD. We hypothesized that this inferiority was due to differences between treatments with regards to their effects on the nasopharyngeal microbiota. The objective was to compare nasal instillation of NORS versus parenteral administration of tilmicosin regarding their effects on the nasopharyngeal microbiota of feedlot cattle at high-risk of developing BRD...
February 9, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28223285/butyrate-regulates-liver-mitochondrial-function-efficiency-and-dynamic-in-insulin-resistant-obese-mice
#11
Maria Pina Mollica, Giuseppina Mattace Raso, Gina Cavaliere, Giovanna Trinchese, Chiara De Filippo, Serena Aceto, Marina Prisco, Claudio Pirozzi, Francesca Di Guida, Adriano Lama, Marianna Crispino, Diana Tronino, Paola Di Vaio, Roberto Berni Canani, Antonio Calignano, Rosaria Meli
Fatty liver, oxidative stress, and mitochondrial dysfunction are key pathophysiological features of insulin resistance and obesity. Butyrate, produced by fermentation in the large intestine by gut microbiota, and its synthetic derivative, the N-(1-carbamoyl-2-phenyl-ethyl) butyramide, FBA, have been demonstrated to be protective against insulin resistance and fatty liver.Here, hepatic mitochondria were identified as the main target of the beneficial effect of both butyrate-based compounds in reverting insulin resistance and fat accumulation in diet induced obese mice...
February 21, 2017: Diabetes
https://www.readbyqxmd.com/read/28215759/impact-of-ageing-and-a-synbiotic-on-the-immune-response-to-seasonal-influenza-vaccination-a-randomised-controlled-trial
#12
Sumia Enani, Agnieszka Przemska-Kosicka, Caroline E Childs, Catherine Maidens, Honglin Dong, Lorenza Conterno, Kieran Tuohy, Susan Todd, Margot Gosney, Parveen Yaqoob
BACKGROUND & AIMS: Ageing increases risk of respiratory infections and impairs the response to influenza vaccination. Pre- and pro-biotics offer an opportunity to modulate anti-viral defenses and the response to vaccination via alteration of the gut microbiota. This study investigated the effect of a novel probiotic, Bifidobacterium longum bv. infantis CCUG 52486, combined with a prebiotic, gluco-oligosaccharide, on the B and T cell response to seasonal influenza vaccination in young and older subjects ...
January 28, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28213779/adenoid-bacterial-colonization-in-a-paediatric-population
#13
João Subtil, João Carlos Rodrigues, Lúcia Reis, Luís Freitas, Joana Filipe, Alberto Santos, Carlos Macor, Aida Duarte, Luisa Jordao
Adenoids play a key role in both respiratory and ear infection in children. It has also been shown that adenoidectomy improves these symptoms in this population. The main goal of the present study was to evaluate adenoid bacterial colonization and document a possible relation with infectious respiratory disease. A prospective observational study was designed to evaluate the proposed hypothesis in a paediatric population submitted to adenoidectomy by either infectious or non-infectious indications and compare these two cohorts...
February 18, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28196762/enteric-helminth-induced-type-i-interferon-signalling-protects-against-pulmonary-virus-infection-through-interaction-with-the-microbiota
#14
Amanda J McFarlane, Henry J McSorley, Donald J Davidson, Paul M Fitch, Claire Errington, Karen J Mackenzie, Eva S Gollwitzer, Chris J C Johnston, Andrew S MacDonald, Michael R Edwards, Nicola L Harris, Benjamin J Marsland, Rick M Maizels, Jürgen Schwarze
BACKGROUND: Helminth parasites have been reported to have beneficial immune modulatory effects in allergic and autoimmune conditions and detrimental consequences in tuberculosis and some viral infections. Their role in co-infection with respiratory viruses is not clear. OBJECTIVE: Here, we investigated the effects of strictly enteric helminth infection with Heligmosomoides polygyrus on respiratory syncytial virus (RSV) infection in a mouse model. METHODS: A murine helminth/ RSV co-infection model was developed...
February 11, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28195747/do-aging-factors-influence-the-clinical-presentation-and-management-of-chronic-rhinosinusitis
#15
Axel E Renteria, Leandra Mfuna Endam, Martin Desrosiers
Objective/Hypothesis Chronic rhinosinusitis (CRS) is a complex inflammatory disease of the upper respiratory airways resulting from the dysregulation of immunity and epithelial defenses. More recently, the contribution of an altered nasal microbiome to the development of CRS has also been proposed. However, the impact of aging on the development of CRS has been long overlooked. Here we propose, in a hypothesis piece, that aging can influence the physiopathology of CRS and its subsequent management in an elderly population...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28133874/the-cutaneous-ecosystem-the-roles-of-the-skin-microbiome-in-health-and-its-association-with-inflammatory-skin-conditions-in-humans-and-animals
#16
REVIEW
Aline Rodrigues Hoffmann
BACKGROUND: Inhabiting a sterile world is no longer an acceptable or desirable concept. Recent studies developed in the microbiome field have unveiled complex microbial populations inhabiting the skin, digestive, respiratory and reproductive tracts. Microbiome studies have opened new venues to explore the human and animal second genome, its functions and its importance in maintaining health. SKIN MICROBIOME IN HEALTH: The composition of the skin microbiome varies across different body sites and across individuals, being influenced by different host habits, including for instance age, sex, diet, hygiene and lifestyle...
February 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28129336/airway-microbial-community-turnover-differs-by-bpd-severity-in-ventilated-preterm-infants
#17
Brandie D Wagner, Marci K Sontag, J Kirk Harris, Joshua I Miller, Lindsey Morrow, Charles E Robertson, Mark Stephens, Brenda B Poindexter, Steven H Abman, Peter M Mourani
Preterm birth exposes the developing lung to an environment with direct exposure to bacteria, often facilitated by endotracheal intubation. Despite evidence linking bacterial infections to the pathogenesis of bronchopulmonary dysplasia (BPD), systematic studies of airway microbiota are limited. The objective was to identify specific patterns of the early respiratory tract microbiome from tracheal aspirates of mechanically ventilated preterm infants that are associated with the development and severity of BPD...
2017: PloS One
https://www.readbyqxmd.com/read/28117832/salivary-mucins-promote-the-coexistence-of-competing-oral-bacterial-species
#18
Erica Shapiro Frenkel, Katharina Ribbeck
Mucus forms a major ecological niche for microbiota in various locations throughout the human body such as the gastrointestinal tract, respiratory tract and oral cavity. The primary structural components of mucus are mucin glycoproteins, which crosslink to form a complex polymer network that surrounds microbes. Although the mucin matrix could create constraints that impact inhabiting microbes, little is understood about how this key environmental factor affects interspecies interactions. In this study, we develop an experimental model using gel-forming human salivary mucins to understand the influence of mucin on the viability of two competing species of oral bacteria...
January 24, 2017: ISME Journal
https://www.readbyqxmd.com/read/28107528/nasopharyngeal-microbiome-diversity-changes-over-time-in-children-with-asthma
#19
Marcos Pérez-Losada, Lamia Alamri, Keith A Crandall, Robert J Freishtat
BACKGROUND: The nasopharynx is a reservoir for pathogens associated with respiratory illnesses such as asthma. Next-generation sequencing (NGS) has been used to characterize the nasopharyngeal microbiome of infants and adults during health and disease; less is known, however, about the composition and temporal dynamics (i.e., longitudinal variation) of microbiotas from children and adolescents. Here we use NGS technology to characterize the nasopharyngeal microbiomes of asthmatic children and adolescents (6 to 18 years) and determine their stability over time...
2017: PloS One
https://www.readbyqxmd.com/read/28105618/-efficacy-analysis-of-fecal-microbiota-transplantation-in-the-treatment-of-406-cases-with-gastrointestinal-disorders
#20
Ning Li, Hongliang Tian, Chunlian Ma, Chao Ding, Xiaolong Ge, Lili Gu, Xuelei Zhang, Bo Yang, Yue Hua, Yifan Zhu, Yan Zhou
OBJECTIVE: To evaluate the efficacy and safety of fecal microbiota transplantation (FMT) for gastrointestinal disorders. METHODS: Retrospective analysis of the clinical data of 406 patients who underwent FMT from May 2014 to April 2016 in the Intestinal Microenvironment Treatment Centre of Nanjing General Hospital was performed, including patients with constipation(276 cases), recurrent Clostridium Difficile infection (RCDI, 61 cases), ulcerative colitis(44 cases), irritable bowel syndrome (15 cases) and Crohn's disease(10 cases)...
January 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
keyword
keyword
78879
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"