keyword
MENU ▼
Read by QxMD icon Read
search

Hypertension AND Neuropathy

keyword
https://www.readbyqxmd.com/read/28277067/platelet-activation-by-adp-is-increased-in-selected-patients-with-anterior-ischemic-optic-neuropathy-or-retinal-vein-occlusion
#1
Claudia Kuhli-Hattenbach, Peter Hellstern, Thomas Kohnen, Lars-Olof Hattenbach
To investigate whether adenosine diphosphate (ADP)-induced platelet hyperaggregability is associated with nonarteritic anterior ischemic optic neuropathy (NAION) or retinal vein occlusion (RVO). We retrospectively reviewed thrombophilia screening data of patients with NAION or RVO without a history of arterial hypertension, diabetes mellitus, hyperlipidemia, obesity, and cigarette abuse. Patients with a positive family history for thromboembolism were not excluded. Platelet aggregation (area under the curve, AUC) after induction of 0...
February 16, 2017: Platelets
https://www.readbyqxmd.com/read/28256395/unmet-need-for-bariatric-surgery
#2
Kate N O'Neill, Francis M Finucane, Carel W le Roux, Anthony P Fitzgerald, Patricia M Kearney
INTRODUCTION: With the rising prevalence of severe obesity and type 2 diabetes (T2D), bariatric surgery offers a clinical and cost-effective treatment for carefully selected patients. Despite this, the provision of surgical services varies significantly between countries. OBJECTIVE: To inform health service planning by estimating the number of people who would potentially benefit from bariatric surgery. SETTING: Nationally representative sample of community-dwelling older adults...
December 23, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28249604/upregulation-of-the-endothelin-a-eta-receptor-and-its-association-with-neurodegeneration-in-a-rodent-model-of-glaucoma
#3
Nolan R McGrady, Alena Z Minton, Dorota L Stankowska, Shaoqing He, Hayden B Jefferies, Raghu R Krishnamoorthy
BACKGROUND: Primary open angle glaucoma is a heterogeneous group of optic neuropathies that results in optic nerve degeneration and a loss of retinal ganglion cells (RGCs) ultimately causing blindness if allowed to progress. Elevation of intraocular pressure (IOP) is the most attributable risk factor for developing glaucoma and lowering of IOP is currently the only available therapy. However, despite lowering IOP, neurodegenerative effects persist in some patients. Hence, it would be beneficial to develop approaches to promote neuroprotection of RGCs in addition to IOP lowering therapies...
March 1, 2017: BMC Neuroscience
https://www.readbyqxmd.com/read/28245334/association-of-type-1-diabetes-vs-type-2-diabetes-diagnosed-during-childhood-and-adolescence-with-complications-during-teenage-years-and-young-adulthood
#4
Dana Dabelea, Jeanette M Stafford, Elizabeth J Mayer-Davis, Ralph D'Agostino, Lawrence Dolan, Giuseppina Imperatore, Barbara Linder, Jean M Lawrence, Santica M Marcovina, Amy K Mottl, Mary Helen Black, Rodica Pop-Busui, Sharon Saydah, Richard F Hamman, Catherine Pihoker
Importance: The burden and determinants of complications and comorbidities in contemporary youth-onset diabetes are unknown. Objective: To determine the prevalence of and risk factors for complications related to type 1 diabetes vs type 2 diabetes among teenagers and young adults who had been diagnosed with diabetes during childhood and adolescence. Design, Setting, and Participants: Observational study from 2002 to 2015 in 5 US locations, including 2018 participants with type 1 and type 2 diabetes diagnosed at younger than 20 years, with single outcome measures between 2011 and 2015...
February 28, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28244936/ischemic-optic-neuropathy-in-cardiac-surgery-incidence-and-risk-factors-in-the-united-states-from-the-national-inpatient-sample-1998-to-2013
#5
Daniel S Rubin, Monica M Matsumoto, Heather E Moss, Charlotte E Joslin, Avery Tung, Steven Roth
BACKGROUND: Ischemic optic neuropathy is the most common form of perioperative visual loss, with highest incidence in cardiac and spinal fusion surgery. To date, potential risk factors have been identified in cardiac surgery by only small, single-institution studies. To determine the preoperative risk factors for ischemic optic neuropathy, the authors used the National Inpatient Sample, a database of inpatient discharges for nonfederal hospitals in the United States. METHODS: Adults aged 18 yr or older admitted for coronary artery bypass grafting, heart valve repair or replacement surgery, or left ventricular assist device insertion in National Inpatient Sample from 1998 to 2013 were included...
February 28, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28114698/-impact-of-drugs-on-glaucoma-and-intraocular-pressure
#6
T Schlote
Purpose Systemic drugs may have unfavourable effects on intraocular pressure, glaucoma and the efficacy of glaucoma drugs. Material and Methods The article provides a review of the literature from PubMed and clinical experience. Results Topical and systemic corticosteroids induce complex changes inside the trabecular meshwork. New genetic results improve the understanding of pathogenetic processes, although many questions are still open. Arterial hypertension and antihypertonic drugs may influence the risk of glaucoma, intraocular pressure and ocular perfusion pressure...
February 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28108140/steroid-treatment-in-ocular-tuberculosis-a-double-edged-sword
#7
S Souissi, T David, L Beral
INTRODUCTION: We report the case of a Caribbean patient with an atypical presentation of bilateral tuberculous chorioretinopathy. PATIENT AND METHODS: A 57-year-old woman, with hypertension and non-insulin dependent diabetes, was referred to our center for a sudden loss of vision in the right eye to hand motions. Ophthalmic examination revealed only right papilledema. Brain magnetic resonance imaging was normal. Laboratory examination revealed no signs of inflammation...
February 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28098594/mediators-of-diabetic-neuropathy-is-hyperglycemia-the-only-culprit
#8
Anna Grisold, Brian C Callaghan, Eva L Feldman
PURPOSE OF REVIEW: Diabetic peripheral neuropathy (DPN) is a disabling, highly prevalent complication of both type 1 and type 2 diabetes mellitus (T1DM and T2DM). Large clinical studies support the concept that, in addition to hyperglycemia, components of the metabolic syndrome (MetS) may underlie the pathogenesis of DPN, especially in T2DM. This review will present the evidence supporting the MetS and its individual components as potential causal factors for the development of neuropathy...
April 2017: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/28050656/the-recommendations-of-a-consensus-panel-for-the-screening-diagnosis-and-treatment-of-neurogenic-orthostatic-hypotension-and-associated-supine-hypertension
#9
REVIEW
Christopher H Gibbons, Peter Schmidt, Italo Biaggioni, Camille Frazier-Mills, Roy Freeman, Stuart Isaacson, Beverly Karabin, Louis Kuritzky, Mark Lew, Phillip Low, Ali Mehdirad, Satish R Raj, Steven Vernino, Horacio Kaufmann
Neurogenic orthostatic hypotension (nOH) is common in patients with neurodegenerative disorders such as Parkinson's disease, multiple system atrophy, pure autonomic failure, dementia with Lewy bodies, and peripheral neuropathies including amyloid or diabetic neuropathy. Due to the frequency of nOH in the aging population, clinicians need to be well informed about its diagnosis and management. To date, studies of nOH have used different outcome measures and various methods of diagnosis, thereby preventing the generation of evidence-based guidelines to direct clinicians towards 'best practices' when treating patients with nOH and associated supine hypertension...
January 3, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28029447/a-phase-ii-evaluation-of-ixabepilone-in-the-treatment-of-recurrent-persistent-carcinosarcoma-of-the-uterus-an-nrg-oncology-gynecologic-oncology-group-study
#10
Carolyn K McCourt, Wei Deng, Don S Dizon, Heather A Lankes, Michael J Birrer, Michele M Lomme, Matthew A Powell, James E Kendrick, Joel N Saltzman, David Warshal, Meaghan E Tenney, David M Kushner, Carol Aghajanian
BACKGROUND: The primary objectives were to determine the objective response rate (ORR) and safety profile of ixabepilone in women with recurrent or persistent uterine carcinosarcoma (UCS). Secondary objectives included progression-free survival (PFS) and overall survival (OS). Exploratory translational objectives included characterization of class III beta tubulin expression and its association with response, PFS, and OS. METHODS: Patients had measurable disease; up to two prior chemotherapeutic regimens were allowed, but must have included a taxane...
January 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28017420/comparison-of-visual-outcomes-of-nonarteritic-anterior-ischemic-optic-neuropathy-in-patients-with-and-without-diabetes-mellitus
#11
Srilakshmi Sharma, Sarah Kwan, Katherine A Fallano, Jiangxia Wang, Neil R Miller, Prem S Subramanian
PURPOSE: Diabetic patients have a greater risk of nonarteritic anterior ischemic optic neuropathy (NAION) than nondiabetic patients. We compare visual outcomes, prevalence of bilateral/sequential ION, and predictors of visual outcomes in NAION between diabetic and nondiabetic patients. DESIGN: Case-control study. PARTICIPANTS: All 231 patients with NAION seen by the Neuro-Ophthalmology Service, Wilmer Eye Institute, between 2002 and 2011 were screened for study inclusion...
December 22, 2016: Ophthalmology
https://www.readbyqxmd.com/read/28003971/optic-neuropathy-and-increased-retinal-glial-fibrillary-acidic-protein-due-to-microbead-induced-ocular-hypertension-in-the-rabbit
#12
Jun Zhao, Tian-Hui Zhu, Wen-Chieh Chen, Shi-Ming Peng, Xiao-Sheng Huang, Kin-Sang Cho, Dong Feng Chen, Guei-Sheung Liu
AIM: To characterize whether a glaucoma model with chronic elevation of the intraocular pressure (IOP) was able to be induced by anterior chamber injection of microbeads in rabbits. METHODS: In order to screen the optimal dose of microbead injection, IOP was measured every 3d for 4wk using handheld applanation tonometer after a single intracameral injection of 10 µL, 25 µL, 50 µL or 100 µL microbeads (5×10(6) beads/mL; n=6/group) in New Zealand White rabbits...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27995424/fragile-x-premutation-in-women-recognizing-the-health-challenges-beyond-primary-ovarian-insufficiency
#13
REVIEW
Luis R Hoyos, Mili Thakur
Fragile X premutation carriers have 55-200 CGG repeats in the 5' untranslated region of the FMR1 gene. Women with this premutation face many physical and emotional challenges in their life. Approximately 20% of these women will develop fragile X-associated primary ovarian insufficiency (FXPOI). In addition, they suffer from increased rates of menstrual dysfunction, diminished ovarian reserve, reduction in age of menopause, infertility, dizygotic twinning, and risk of having an offspring with a premutation or full mutation...
March 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/27990740/hypertensive-eye-disease-a-review
#14
REVIEW
Samantha Fraser-Bell, Richard Symes, Anagha Vaze
Hypertension is a risk factor for a number of vision-threatening eye conditions including retinal vascular occlusion, retinal macroaneurysm and non arteritic anterior ischaemic optic neuropathy. In addition, hypertension may exacerbate the vision-threatening effects of diabetic retinopathy and has been implicated in the pathogenesis of age-related macular degeneration. The effects of sustained hypertension are directly visible in the eye as hypertensive retinopathy and choroidopathy, reflecting a pathological process occurring throughout the body...
January 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27990358/neuropathy-optic-glaucomatosa-induced-by-systemic-hypertension-through-activation-endothelin-1-signaling-pathway-in-central-retinal-artery-in-rats
#15
Seskoati Prayitnaningsih, Hidayat Sujuti, Maksum Effendi, Aulia Abdullah, Nanda Wahyu Anandita, Febriani Yohana, Nur Permatasari, Mohamad Aris Widodo
AIM: To evaluate effect of hypertension on retinal ganglion cell (RGC) apoptosis, intraocular pressure (IOP), and the activation of endothelin-1 (ET-1) signaling pathway in central retinal artery (CRA) in rats. METHODS: The experimental study was performed on 20 male Sprague Dawley rats that were divided into control group, and hypertension groups. The hypertension was induced by subcutaneous deoxycorticoacetate (DOCA) 10 mg/kg twice a week and administered 0.9% NaCl solution daily for 2, 6, and 10wk...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27982422/update-review-of-the-acute-porphyrias
#16
REVIEW
Penelope E Stein, Michael N Badminton, David C Rees
Acute porphyrias are rare inherited disorders due to deficiencies of haem synthesis enzymes. To date, all UK cases have been one of the three autosomal dominant forms, although penetrance is low and most gene carriers remain asymptomatic. Clinical presentation is typically with acute neurovisceral attacks characterised by severe abdominal pain, vomiting, tachycardia and hypertension. Severe attacks may be complicated by hyponatraemia, peripheral neuropathy sometimes causing paralysis, seizures and psychiatric features...
December 16, 2016: British Journal of Haematology
https://www.readbyqxmd.com/read/27973924/sexual-dysfunction-in-female-patients-with-type-2-diabetes-mellitus-a-cross-sectional-single-centre-study-among-turkish-patients
#17
Ercan Tuncel, Onur Durgun, Hande Peynirci, Canan Ersoy
The aim of the study was to assess the prevalence of female sexual function and related factors in Turkish women with type 2 diabetes mellitus (T2DM). A total of 93 female patients diagnosed with T2DM (age 48.0 ± 7.2 years (Mean ± SD) were included. Data on age, diabetes age, HbA1c level, educational level, diabetes treatment, diabetes-related complications, co-morbid disorders and concomitant medications were recorded, as were the scores obtained using a Female Sexual Function Index (FSFI) questionnaire...
December 14, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27965983/xanthine-oxidase-activity-in-type-2-diabetes-mellitus-patients-with-and-without-diabetic-peripheral-neuropathy
#18
Dijana J Miric, Bojana M Kisic, Snezana Filipovic-Danic, Rade Grbic, Ilija Dragojevic, Marko B Miric, Dragana Puhalo-Sladoje
This study investigated the relationship between serum xanthine oxidase (XOD) activity and the occurrence of diabetic peripheral neuropathy (DPN) in type 2 diabetes mellitus (T2DM) patients. Serum XOD activity, ischemia-modified albumin (IMA), uric acid (UA), albumin, glycated hemoglobin (HbA1c), advanced glycation end products (AGE), total free thiols, atherogenic index of plasma (AIP), and body mass index (BMI) were measured in 80 T2DM patients (29 with and 51 without DPN), and 30 nondiabetic control subjects...
2016: Journal of Diabetes Research
https://www.readbyqxmd.com/read/27941053/patient-characteristics-related-to-metabolic-disorders-and-chronic-complications-in-type-2-diabetes-mellitus-patients-hospitalized-at-the-qingdao-endocrine-and-diabetes-hospital-from-2006-to-2012-in-china
#19
Yanhu Dong, Weiguo Gao, Lei Zhang, Jia Wei, Niklas Hammar, Claudia S Cabrera, Xiaoli Wu, Qing Qiao
OBJECTIVE: To study the clinical characteristics related to metabolic disorders and complications in type 2 diabetes mellitus patients hospitalized in the Qingdao Endocrine and Diabetes Hospital from 2006 to 2012 in Qingdao, China. PATIENT POPULATION AND METHODS: Data from 14,289 (51% males) type 2 diabetes mellitus patients hospitalized between 2006 and 2012 were collected and analysed. Information on patients' demographic, anthropometric, laboratory and disease histories were extracted from electronic medical records...
January 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/27914592/hyperuricemia-in-systemic-lupus-erythematosus-is-it-associated-with-the-neuropsychiatric-manifestations-of-the-disease
#20
Mahdi Sheikh, Shafieh Movassaghi, Mohammad Khaledi, Maryam Moghaddassi
OBJECTIVES: To assess the association between hyperuricemia and different neuropsychiatric manifestations and stroke risk factors in systematic lupus erythematosus (SLE) patients. METHODS: This study was conducted on 204 SLE patients who were admitted to a tertiary referral center. A standardized questionnaire was completed for all the participants and the medical records were reviewed regarding the occurrence of arterial or venous thrombotic events, stroke, seizure, depression, headache, psychosis, and peripheral neuropathy...
November 2016: Revista Brasileira de Reumatologia
keyword
keyword
78875
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"