Andrea Montesel, Raheeba Pakeer Muhammed, Swati Chandak, Dimitrios Kazantzis, Sridevi Thottarath, Shruti Chandra, Victor Chong, Benjamin J L Burton, Geeta Menon, Ian Pearce, Martin McKibbin, Ajay Kotagiri, James Talks, Anna Grabowska, Faruque Ghanchi, Richard Gale, Andrea Giani, Taffeta Ching Ning Yamaguchi, Sobha Sivaprasad
PURPOSE: To describe the prevalence of subretinal transient hyporeflectivity (STHR) in exudative neovascular age-related macular degeneration (nAMD) and its response to a loading phase of aflibercept. METHODS: Optical coherence tomography (OCT) scans of treatment-naïve nAMD patients captured at baseline and after a loading phase of aflibercept were graded for presence of STHR, defined as a small, well-defined, round, subretinal, hyporeflective area, delimited between the ellipsoid zone (EZ) and the retinal pigmented epithelium/Bruch membrane complex...
April 23, 2024: Eye