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https://www.readbyqxmd.com/read/29244755/doped-halloysite-nanotubes-for-use-in-the-3d-printing-of-medical-devices
#1
Jeffery A Weisman, Udayabhanu Jammalamadaka, Karthik Tappa, David K Mills
Previous studies have established halloysite nanotubes (HNTs) as viable nanocontainers capable of sustained release of a variety of antibiotics, corrosion agents, chemotherapeutics and growth factors either from their lumen or in outer surface coatings. Accordingly, halloysite nanotubes (HNTs) hold great promise as drug delivery carriers in the fields of pharmaceutical science and regenerative medicine. This study explored the potential of 3D printing drug doped HNT constructs. We used a model drug, gentamicin (GS) and polylactic acid (PLA) to fabricate GS releasing disks, beads, and pellets...
December 15, 2017: Bioengineering
https://www.readbyqxmd.com/read/29244241/vitamin-d-and-gestational-diabetes-mellitus-a-systematic-review-based-on-data-free-of-hawthorne-effect
#2
Yanbo Zhang, Yunhui Gong, Hongmei Xue, Jingyuan Xiong, Guo Cheng
BACKGROUND: Gestational diabetes mellitus (GDM) is an increasingly prevalent disorder, associated with low blood vitamin D (VD) level. OBJECTIVES: To evaluate the relationship between VD and GDM. SEARCH STRATEGY: EMBASE, MEDLINE, Cochrane library and China Biology Medicine disc were searched till May 2017. The references of previous studies were screened. SELECTION CRITERIA: Observational studies on the relationship between VD and GDM free from Hawthorne effect and randomized controlled trials of VD supplementation during pregnancy for preventing or treating GDM were included...
December 15, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29243674/turmeric-a-condiment-cosmetic-and-cure
#3
REVIEW
Hima Gopinath, Kaliaperumal Karthikeyan
Turmeric (Curcuma longa L.) is an integral part of Asian culture and cuisine. It has been used in traditional medicine since centuries. A myriad of health benefits have been attributed to it. Curcumin, the most biologically active curcuminoid in turmeric, is being investigated in pre-clinical and clinical trials for its role in disease prevention and cure. It has antioxidant, anti-inflammatory, antineoplastic, anti-proliferative and antimicrobial effects. We review the chemistry of this plant, its cultural relevance in Indian skin care, and its uses in dermatology...
December 14, 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/29242996/personalized%C3%A2-health-monitoring%C3%A2-system-for-managing-well-being-in-rural-areas
#4
Prema Nedungadi, Akshay Jayakumar, Raghu Raman
Rural India lacks easy access to health practitioners and medical centers, depending instead on community health workers. In these areas, common ailments that are easy to manage with medicines, often lead to medical escalations and even fatalities due to lack of awareness and delayed diagnosis. The introduction of wearable health devices has made it easier to monitor health conditions and to connect doctors and patients in urban areas. However, existing initiatives have not succeeded in providing adequate health monitoring to rural and low-literate patients, as current methods are expensive, require consistent connectivity and expect literate users...
December 14, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/29241720/physician-training-in-cancer-prevention-and-control-a-population-health-imperative
#5
Miranda A Moore, Richard A Goodman
Cancer is the second leading cause of morbidity and mortality in the U.S. Although reducing the number of new cancer cases is a national health goal, the continuing growth of the older adult population ensures that the burden of cancer will increase. Despite documentation of the shortage of oncologists to meet the growing need, relatively limited attention has been focused on increasing the physician workforce trained in the prevention and control of cancer. The existing physician workforce with such specialized training in cancer prevention and control is small, aging, increasing at a low rate, and likely to decrease because of an imbalance between retiring physicians and new entrants...
December 11, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29241506/quality-of-life-and-self-care-in-elderly-patients-with-cardiovascular-diseases-the-effect-of-a-traditional-chinese-medicine-health-educational-intervention
#6
Yi-Qin Sun, An-Li Jiang, San-Mei Chen, Hui Li, Hai-Yan Xing, Fang Wang
AIMS: To explore the effects of a Traditional Chinese Medicine health educational intervention on the quality of life and self-care agency of elderly patients living with chronic cardiovascular disease. BACKGROUND: Cardiovascular disease is a leading cause of morbidity and mortality worldwide. The secondary prevention and treatment for chronic cardiovascular disease emphasize the importance of lifestyle modification. However, behavior-changing is difficult and individual choices are influenced by broader environmental factors...
December 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/29241373/agreement-between-the-point-of-care-tests-for-microalbuminuria-and-hba1c-performed-in-mexican-family-medicine-units-and-the-results-of-standard-laboratory-tests
#7
Leticia A Valdez-González, Araceli Méndez-Padrón, Rita A Gómez-Díaz, Adán Valladares-Salgado, Martha Catalina Sánchez-Becerra, Rafael Mondragón-González, Jaime Hernández-Rubí, Arturo González-Hermosillo, Miguel Cruz, Víctor Borja, Niels H Wacher
The albumin-creatinine ratio is considered an indicator of microalbuminuria, precursor to chronic kidney disease, while HbA1c is used to measure glycemic control. Given the prevalence of diabetes-related nephropathy, spot testing of albumin has long been recommended as a preventative measure, for the timely detection of microalbuminuria. However, many countries do not have this testing available in primary care, and sometimes not even in second- and third-level care. The objective of this study was to compare agreement of the microalbuminuria and HbA1c results obtained in the laboratory with 'gold standard' techniques, with those obtained on site with a 'Point of Care' DCA Vantage™ device by Siemens...
December 15, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/29239871/integrative-medicine-as-an-adjunct-to-orthopaedic-surgery
#8
James R Ficke, Nathan M Moroski, Steven D Ross, Ranjan Gupta
Patients often seek nontraditional forms of treatment, including alternative/complementary medical options, such as chiropractic care and acupuncture, to meet their personal needs. In the United States, interest has grown in methods to reduce pain and improve function through Ayurvedic medicine, which uses plant-based supplements, such as turmeric. Traditional allopathic medicine attempts to provide patients with evidence-based therapeutic regimens for their musculoskeletal conditions. Integrative medicine often is used to prevent and manage the sequelae associated with injuries and illnesses; however, competitive athletes and military personnel use complementary medicine for performance enhancement...
December 11, 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29239679/primary-care-variability-in-patients-at-higher-risk-for-colorectal-cancer-evaluation-of-screening-and-preventive-care-practices
#9
John Peabody, Juan-Sebastien Salvidar, Eric Swagel, Steven Fugaro, David Paculdo, Mary Tran
OBJECTIVE: Sub-optimal colorectal cancer (CRC) evaluations have been attributed to both physician and patient factors. The primary objective of this study was to evaluate physician practice variation in patients with a higher risk of CRC. We wanted to identify the physician characteristics and the types of patient that were associated with missed screening opportunities; we also explored whether screening for CRC served as a proxy for better preventive care practices. METHODS: 213 board-certified family and internal medicine physicians participated in the study, conducted between September and December 2016...
December 14, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29239587/redefining-medical-care
#10
Lauren R Roth
President Donald J. Trump has said he will repeal the Affordable Care Act (ACA) and replace it with health savings accounts (HSAs). Conservatives have long preferred individual accounts to meet social welfare needs instead of more traditional entitlement programs. The types of "medical care" that can be reimbursed through an HSA are listed in section 213(d) of the Internal Revenue Code (Code) and include expenses "for the diagnosis, cure, mitigation, treatment, or prevention of disease, or for the purpose of affecting any structure or function of the body...
2017: Cornell Journal of Law and Public Policy
https://www.readbyqxmd.com/read/29239150/gender-differences-in-septic-intensive-care-unit-patients
#11
Francesco Campanelli, Giovanni Landoni, Luca Cabrini, Alberto Zangrillo
BACKGROUND: The world population is mostly male at birth, although there is a shift in predominance over 55 years of age with more females than males. Male gender was recently hypothesized to be a risk factor for sepsis and septic shock; the reasons and the consequences of this odd discrepancy are yet a matter of debate. We investigated the percentage of males and females in a large number of trials performed on septic adult patients admitted to Intensive Care Units. METHODS: We analysed all the multicentre randomized controlled trials ever published in peer-reviewed Journals reporting a significant effect on mortality in intensive care unit septic adult patients; furthermore, we retrieved all the manuscripts dealing with sepsis or septic shock patients published in the last 3 years in the three medical Journals with the highest impact factor...
December 13, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29238699/ticks-and-tick-borne-pathogens-of-the-caribbean-current-understanding-and-future-directions-for-more-comprehensive-surveillance
#12
REVIEW
Mathilde Gondard, Alejandro Cabezas-Cruz, Roxanne A Charles, Muriel Vayssier-Taussat, Emmanuel Albina, Sara Moutailler
Ticks are obligate hematophagous arthropods of significant importance to human and veterinary medicine. They transmit a vast array of pathogens, including bacteria, viruses, protozoa, and helminths. Most epidemiological data on ticks and tick-borne pathogens (TBPs) in the West Indies are limited to common livestock pathogens such as Ehrlichia ruminantium, Babesia spp. (i.e., B. bovis and B. bigemina), and Anaplasma marginale, and less information is available on companion animal pathogens. Of note, human tick-borne diseases (TBDs) remain almost completely uncharacterized in the West Indies...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29237686/toward-genetics-driven-early-intervention-in-dilated-cardiomyopathy-design-and-implementation-of-the-dcm-precision-medicine-study
#13
REVIEW
Daniel D Kinnamon, Ana Morales, Deborah J Bowen, Wylie Burke, Ray E Hershberger
BACKGROUND: The cause of idiopathic dilated cardiomyopathy (DCM) is unknown by definition, but its familial subtype is considered to have a genetic component. We hypothesize that most idiopathic DCM, whether familial or nonfamilial, has a genetic basis, in which case a genetics-driven approach to identifying at-risk family members for clinical screening and early intervention could reduce morbidity and mortality. METHODS: On the basis of this hypothesis, we have launched the National Heart, Lung, and Blood Institute- and National Human Genome Research Institute-funded DCM Precision Medicine Study, which aims to enroll 1300 individuals (600 non-Hispanic African ancestry, 600 non-Hispanic European ancestry, and 100 Hispanic) who meet rigorous clinical criteria for idiopathic DCM along with 2600 of their relatives...
December 2017: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/29237450/adding-chinese-herbal-medicine-to-conventional-therapy-brings-cognitive-benefits-to-patients-with-alzheimer-s-disease-a-retrospective-analysis
#14
Jing Shi, Jingnian Ni, Tao Lu, Xuekai Zhang, Mingqing Wei, Ting Li, Weiwei Liu, Yongyan Wang, Yuanyuan Shi, Jinzhou Tian
BACKGROUND: Conventional therapy (CT) such as donepezil and memantine are well-known short-term treatments for the symptoms of Alzheimer's disease (AD). The efficacy of them, however, drops below baseline level after 9 months. In China, herbal therapy as a complementary therapy is very popular. Should conventional therapy combined with herbal therapy (CT + H) make add-on benefit? METHODS: In this retrospective cohort study, 344 outpatients diagnosed as probable dementia due to AD were collected, with the treatment of either CT + H or CT alone in clinical settings...
December 13, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29237288/the-effect-of-continuous-glucose-monitoring-in-preventing-inpatient-hypoglycemia-in-general-wards-the-glucose-telemetry-system
#15
Elias K Spanakis, David L Levitt, Tariq Siddiqui, Lakshmi G Singh, Lillian Pinault, John Sorkin, Guillermo E Umpierrez, Jeffrey C Fink
BACKGROUND: Few studies have examined the use of continuous glucose monitoring (CGM) devices in the general wards. The aim of this pilot study was to examine whether CGM readings can be successfully transmitted from the bedside to a central monitoring device in the nursing station, and whether a glucose telemetry system can prevent hypoglycemic events. METHODS: We present pilot data on 5 consecutive insulin treated general medicine patients with type 2 diabetes (T2DM) whose glucose values were observed with CGM (DEXCOM) and the results were transmitted to a central nursing station monitoring system using DEXCOM Follow and Share 2 software...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29237222/-surgery-during-pregnancy-regulations-and-requirements
#16
Frauke Fritze-Büttner, Ronny Dittmar, Maya Niethard
Due to the marked increase in the numbers of women in medicine, professional and political discussions on equality among doctors are gaining increasing attention. One such issue is "operating during pregnancy". As a result of existing legislation and federal regulations, it has been virtually impossible for pregnant surgeons to continue their surgical work. After approval by the Federal Council or Bundesrat, the revised Maternity Protection Act will come into force on 01.01.2018. It will thereafter be easier for surgeons to operate during pregnancy...
December 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29236917/a-novel-body-mass-index-reference-range-an-observational-study
#17
Sirlei Siani Morais, Mirena Ide, Andrea Moreno Morgan, Fernanda Garanhani Surita
OBJECTIVE: To generate a new body mass index curve of reference values and ranges for body mass index and weight gain during pregnancy and to compare the new curve and weight gain ranges with the currently used references. METHODS: A prospective observational study was conducted with a total of 5,656 weight and body mass index measurements in 641 women with single pregnancy who attended their first prenatal visit before 12 weeks. All the women were over 18 years old and had no medical conditions that would influence body mass index...
November 2017: Clinics
https://www.readbyqxmd.com/read/29236859/mentha-pulegium-crude-extracts-induce-thiol-oxidation-and-potentiate-hemolysis-when-associated-to-t-butyl-hydroperoxide-in-human-s-erythrocytes
#18
Matheus C Bianchini, Dennyura O Galvão, Tatiana Tamborena, Claudia O Alves, Robson L Puntel
Mentha pulegium (Lamiaceae) tea has been used as a traditional medicine; however, the modulatory effect of M. pulegium extracts on damage to human erythrocytes associated to t-butyl hydroperoxide (t-BHP) exposure remains to be investigated. Accordingly, we perform this study in order to test the hypothesis that aqueous and ethanolic extracts of M. pulegium could modulate the hemolysis associated to t-BHP exposure, non-protein thiol (NPSH) oxidation and lipid peroxidation (measured as thiobarbituric acid reactive substances - TBARS) in human erythrocytes...
December 11, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29236427/sharing-samples-and-generics-an-antitrust-framework
#19
Michael A Carrier
Rising drug prices are in the news. By increasing price, drug companies have placed vital, even life-saving, medicines out of the reach of consumers. In a recent development, brand firms have prevented generics even from entering the market. The ruse for this strategy involves risk-management programs known as Risk Evaluation and Mitigation Strategies ("REMS"). Pursuant to legislation enacted in 2007, the FDA requires REMS when a drug's risks (such as death or injury) outweigh its rewards. Brands have used this regime, intended to bring drugs to the market, to block generic competition...
2017: Cornell Law Review
https://www.readbyqxmd.com/read/29235230/multidimensional-factors-associated-with-the-loss-of-independence-a-population-based-longitudinal-study
#20
Mai Kabayama, Hiroshi Mikami, Kei Kamide
AIM: To clarify the factors associated with loss of independence multidimensionally over a 3-year period among community-dwelling older adults. METHODS: The survey was exclusively carried out by the local government for people aged >65 years who were independent at baseline living in H-City, a mid-sized urban city in Japan. The participants completed a self-administered postal questionnaire, and we obtained data regarding their loss of independence from administrative records 3 years later...
December 13, 2017: Geriatrics & Gerontology International
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