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https://www.readbyqxmd.com/read/28066570/current-therapy-of-eisenmenger-syndrome
#1
EDITORIAL
Minsu Kim, Wook-Jin Chung
No abstract text is available yet for this article.
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28027769/brain-metabolite-alterations-in-eisenmenger-syndrome-evaluation-with-mr-proton-spectroscopy
#2
Dilek Şen Dokumacı, Ferit Doğan, Ali Yıldırım, Fatıma Nurefşan Boyacı, Erol Bozdoğan, Bülent Koca
OBJECTIVE: Eisenmenger syndrome (ES) is a life-threatening disease characterized by pulmonary hypertension and cyanosis in patients with congenital heart diseases. The aim of this study was to determine the brain metabolite changes in Eisenmenger syndrome compared with a control group using MR proton spectroscopy. METHODS AND MATERIALS: The study included 10 children (3 male, 7 female) with congenital heart diseases and a diagnosis of Eisenmenger syndrome. The control group consisted of 10 healthy volunteer children...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28011668/cardiac-remodelling-amongst-adults-with-various-aetiologies-of-pulmonary-arterial-hypertension-including-eisenmenger-syndrome-implications-on-survival-and-the-role-of-right-ventricular-transverse-strain
#3
Pamela Moceri, Priscille Bouvier, Delphine Baudouy, Konstantinos Dimopoulos, Pierre Cerboni, Stephen J Wort, Denis Doyen, Elie-Dan Schouver, Pierre Gibelin, Roxy Senior, Michael A Gatzoulis, Emile Ferrari, Wei Li
AIMS: Survival in pulmonary arterial hypertension (PAH) and Eisenmenger syndrome (ES) relates to right ventricular (RV) function. Little is known about differences of ventricular function between ES patients and those suffering from other PAH aetiologies. In this study, we compared global ventricular function assessed by speckle-tracking in adult patients with ES, other PAH aetiologies, or healthy controls; and assessed the relationship between ventricular function and survival. METHODS AND RESULTS: We performed a prospective cohort study recruiting 83 adult PAH patients (43 ES and 40 other PAH aetiologies patients) and 37 controls between March 2011 and June 2015...
December 23, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27979875/predictors-of-death-in-contemporary-adult-patients-with-eisenmenger-syndrome-a-multicentre-study
#4
Aleksander Kempny, Cristel S Hjortshøj, Hong Gu, Wei Li, Alexander R Opotowsky, Michael Landzberg, Annette S Jensen, Lars Søndergaard, Mette-Elise Estensen, Ulf Thilén, Werner Budts, Barbara J Mulder, Ilja M Blok, Lidia Tomkiewicz-Pajak, Kamil Szostek, Michele D'Alto, Giancarlo Scognamiglio, Katja Prokšelj, Gerhard-Paul Diller, Konstantinos Dimopoulos, Stephen J Wort, Michael A Gatzoulis
BACKGROUND: -Eisenmenger syndrome (ES) is associated with substantial morbidity and mortality. There is no consensus, however, on mortality risk stratification. We aimed to investigate survival and predictors of death in a large, contemporary cohort of ES patients. METHODS: -We identified in a multicentre approach adults with ES under follow-up between 2000 and 2015. We examined survival and its association with clinical, electrocardiographic, echocardiographic and laboratory parameters...
December 15, 2016: Circulation
https://www.readbyqxmd.com/read/27974976/sinus-venosus-atrial-septal-defect-complicated-by-eisenmenger-syndrome-and-the-role-of-vasodilator-therapy
#5
Amornpol Anuwatworn, Maheedhar Gedela, Edgard Bendaly, Julia A Prescott-Focht, Jimmy Yee, Richard Clark, Orvar Jonsson
Sinus venosus atrial septal defect is a rare congenital, interatrial communication defect at the junction of the right atrium and the vena cava. It accounts for 5-10% of cases of all atrial septal defects. Due to the rare prevalence and anatomical complexity, diagnosing sinus venous atrial septal defects poses clinical challenges which may delay diagnosis and treatment. Advanced cardiac imaging studies are useful tools to diagnose this clinical entity and to delineate the anatomy and any associated communications...
2016: Case Reports in Cardiology
https://www.readbyqxmd.com/read/27892598/a-novel-substrate-for-multisensor-hyperspectral-imaging
#6
J Ofner, J Kirschner, E Eitenberger, G Friedbacher, A Kasper-Giebl, H Lohninger, C Eisenmenger-Sittner, B Lendl
The quality of chemical imaging, especially multisensor hyperspectral imaging, strongly depends on sample preparation techniques and instrumental infrastructure but also on the choice of an appropriate imaging substrate. To optimize the combined imaging of Raman microspectroscopy, scanning-electron microscopy and energy-dispersive X-ray spectroscopy, a novel substrate was developed based on sputtering of highly purified aluminium onto classical microscope slides. The novel aluminium substrate overcomes several disadvantages of classical substrates like impurities of the substrate material and contamination of the surface as well as surface roughness and homogeneity...
November 28, 2016: Journal of Microscopy
https://www.readbyqxmd.com/read/27866929/long-term-outcomes-of-pulmonary-arterial-hypertension-under-specific-drug-therapy-in-eisenmenger-syndrome
#7
Sébastien Hascoët, Alban-Elouen Baruteau, Marc Humbert, Gérald Simonneau, Xavier Jais, Jérôme Petit, Daniela Laux, Olivier Sitbon, Virginie Lambert, André Capderou
BACKGROUND: The long-term effectiveness of pulmonary arterial hypertension-specific drug therapy (PAH-SDT) in Eisenmenger syndrome is controversial. We investigated short-term and long-term hemodynamic changes under PAH-SDT and their associations with outcomes in a bicentric cohort. METHODS: Over 20 years, we included 69 patients with congenital heart disease, an indexed pulmonary vascular resistance (PVRi) >8 WU·m(2), and 292 standardized catheterizations at baseline and after PAH-SDT initiation or intensification...
October 15, 2016: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/27852228/pregnancy-outcome-in-women-with-eisenmenger-s-syndrome-a-case-series-from-west-china
#8
Ruiqi Duan, Xiumei Xu, Xiaodong Wang, Haiyan Yu, Yong You, Xinghui Liu, Aiyun Xing, Rong Zhou, Mingrong Xi
BACKGROUND: Eisenmenger's syndrome (ES) consists of pulmonary hypertension with a reversed or bidirectional shunt at the atrioventricular, or aortopulmonary level. The cardiovascular changes that occur during the pregnancy contribute to the high maternal morbidity and mortality in patients with ES. This study is to assess maternal and fetal outcomes in patients with ES. METHODS: This study is a retrospective analysis of 11 pregnancies in women with ES who delivered at a tertiary care center in west China between 2010 and 2014...
November 16, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27849306/eisenmenger-syndrome-in-pregnancy
#9
Shi-Min Yuan
Eisenmenger syndrome is very rare in pregnant women. Debates remain concerning the management of Eisenmenger syndrome in this patient population and the prognosis is unclear in terms of maternal and fetoneonatal outcomes. Epidural analgesia is preferred for Cesarean section as it alleviates perioperative pain and reduces the pulmonary and systemic vascular resistances. Maternal mortality in the presence of Eisenmenger syndrome is reported as 30-50% and even up to 65% in those with Cesarean section. The major causes of death could be hypovolemia, thromboembolism and preeclampsia...
July 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27846671/pulmonary-artery-dissection-in-a-patient-with-eisenmenger-s-syndrome-and-successful-conservative-medical-treatment
#10
Sun Hwa Hong, Kyung-Hee Kim
No abstract text is available yet for this article.
January 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27816173/-sex-differences-in-congenital-heart-disease
#11
P Aubry, H Demian
Gender influences the clinical presentation and the management of some acquired cardiovascular diseases, such as coronary artery disease, resulting in different outcomes. Differences between women and men are also noticed in congenital heart disease. They are mainly related to the prevalence and severity of some congenital heart defects at birth, and in adulthood to the prognosis, incidence of Eisenmenger syndrome and risks of pregnancy. The role of gender on the risk of operative mortality of congenital heart surgery remains debated...
December 2016: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/27767324/brain-diffusion-changes-in-eisenmenger-syndrome
#12
Ferit Dogan, Dilek Sen Dokumaci, Ali Yildirim, Erol Bozdogan, Fatima N Boyaci, Bulent Koca, Ekrem Karakas
OBJECTIVE: This preliminary study aimed to evaluate whether there are changes in the apparent diffusion coefficient (ADC) values of the brain in patients presenting with Eisenmenger syndrome (ES). METHODS: This cross-sectional study included 10 consecutively recruited patients with ES and 10 healthy control subjects. In the patients and controls, eight distinct neuroanatomical locations were selected for analysis. Quantitative measurements of ADC values of the frontal white matter (FWM), occipital white matter, lentiform nucleus (LN), thalamus, frontal cortex, anterior and posterior limbs of the internal capsule and caudate nucleus were measured...
December 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27753979/os-12-06-effect-of-long-term-iloprost-treatment-on-the-right-ventricular-function-in-patients-with-eisenmenger-syndrome
#13
Kyoung Im Cho, Min Gu Chon
OBJECTIVE: Inhaled ilroprost can improve clinical status and symptoms in Eisenmenger syndrome (ES). Right ventricular (RV) function is important prognostic factor of pulmonary arterial hypertension. But there has been insufficient data in echocardiographic parameters related to RV function after long term iloprost therapy. So we evaluated effect of long term iloprost treatment on RV function and other parameters measured by echocardiography in this study. DESIGN AND METHOD: Eleven consecutive patients with ES associated with congenital heart disease underwent echocardiographic measurements at baseline and 48 weeks after iloprost therapy...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753751/the-segmental-contour-pattern
#14
Laura B Eisenmenger, Howard Mann
No abstract text is available yet for this article.
November 2016: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/27727969/eisenmenger-syndrome-in-an-adult-patient-with-aortopulmonary-window
#15
Nerusu Hari Babu
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27713810/the-clinical-course-of-patients-with-atrial-septal-defects
#16
Mostafa Behjati-Ardakani, Mohammad Golshan, Sedigheh Akhavan-Karbasi, Seyed-Masood Hosseini, Mohammad-Amin Behjati-Ardakani, Mohammadtaghi Sarebanhassanabadi
BACKGROUND: Atrial septal defect (ASD) is a common congenital heart disease. OBJECTIVES: The aim of this study was to assess the clinical course of ASD, as well as its frequency of spontaneous closure and regression of diameter. METHODS: In a study conducted from 2000 to 2011, 192 consecutive patients with an isolated ASD were followed up regularly with periodic echocardiographic evaluations according to a standardized protocol. The study was conducted in two series of patients: infants and children and adults...
August 2016: Iranian Journal of Pediatrics
https://www.readbyqxmd.com/read/27713195/-cardiac-function-after-lung-transplantation-of-eisenmenger-syndrome
#17
Soichiro Funaki, Yasushi Shintani, Masato Minami, Takayoshi Ueno, Koichi Toda, Yoshiki Sawa, Meinoshin Okumura
Eisenmenger syndrome(ES) could occur at the end-stage of congenital heart disease and is one of the indications for lung transplantation. Survival following heart-lung transplantation is better than that following bilateral lung transplantation (LT). However, in Japan, because of limitations in regard to the numbers of donors available, LT with cardiac repair is usually chosen. Following LT with cardiac repair, careful management of the repaired heart is necessary, though there are few reports available regarding such postoperative cardiac management...
October 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27648950/long-term-outcome-of-patients-with-perimembranous-ventricular-septal-defect-results-from-the-belgian-registry-on-adult-congenital-heart-disease
#18
Charlien Gabriels, Julie De Backer, Agnes Pasquet, Bernard P Paelinck, Marielle Morissens, Frederik Helsen, Alexander Van De Bruaene, Werner Budts
OBJECTIVES: Studies evaluating the long-term outcome of adults with ventricular septal defect (VSD) are important to inform patients about prognosis. This study investigated the long-term outcome of patients with perimembranous VSD (pmVSD) followed in the Belgian Registry on Adult Congenital Heart Disease. METHODS: All pmVSD patients in the registry were analyzed. RESULTS: Two hundred and sixty-six patients were studied. Fifteen patients had Eisenmenger syndrome...
September 21, 2016: Cardiology
https://www.readbyqxmd.com/read/27643376/os-12-06-effect-of-long-term-iloprost-treatment-on-the-right-ventricular-function-in-patients-with-eisenmenger-syndrome
#19
Kyoung Im Cho, Min Gu Chon
OBJECTIVE: Inhaled ilroprost can improve clinical status and symptoms in Eisenmenger syndrome (ES). Right ventricular (RV) function is important prognostic factor of pulmonary arterial hypertension. But there has been insufficient data in echocardiographic parameters related to RV function after long term iloprost therapy. So we evaluated effect of long term iloprost treatment on RV function and other parameters measured by echocardiography in this study. DESIGN AND METHOD: Eleven consecutive patients with ES associated with congenital heart disease underwent echocardiographic measurements at baseline and 48 weeks after iloprost therapy...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27568461/elevated-serum-hmgb1-in-pulmonary-arterial-hypertension-secondary-to-congenital-heart-disease
#20
Yi-Yuan Huang, Wei Su, Zhao-Wei Zhu, Liang Tang, Xin-Qun Hu, Sheng-Hua Zhou, Zhen-Fei Fang, Jiang Li
AIMS: This study investigated the potential value of serum high mobility group box-1 (HMGB1) level in the diagnosis, staging and treatment response of patients with pulmonary arterial hypertension secondary to congenital heart disease (PAH-CHD). METHODS AND RESULTS: This was a single-center prospective study in 106 CHD patients. Serum HMGB1 levels were measured by enzymelinked immunosorbent assay. HMGB1 levels were significantly increased in patients with PAH compared to patients without PAH (P<0...
October 2016: Vascular Pharmacology
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