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Gino Soldati

Libertario Demi, Wim van Hoeve, Ruud J G van Sloun, Gino Soldati, Marcello Demi
B-lines are ultrasound-imaging artifacts, which correlate with several lung-pathologies. However, their understanding and characterization is still largely incomplete. To further study B-lines, lung-phantoms were developed by trapping a layer of microbubbles in tissue-mimicking gel. To simulate the alveolar size reduction typical of various pathologies, 170 and 80 µm bubbles were used for phantom-type 1 and 2, respectively. A normal alveolar diameter is approximately 280 µm. A LA332 linear-array connected to the ULA-OP platform was used for imaging...
October 6, 2017: Scientific Reports
Gino Soldati, Andrea Smargiassi, Alberto A Mariani, Riccardo Inchingolo
Medical approach to patients is a fundamental step to get the correct diagnosis. The aim of this paper is to analyze some aspects of the reasoning process inherent in medical diagnosis in our era. Pathologic signs (anamnestic data, symptoms, semiotics, laboratory and strumental findings) represent informative phenomena to be integrated for inferring a diagnosis. Thus, diagnosis begins with "signs" and finishes in a probability of disease. The abductive reasoning process is the generation of a hypothesis to explain one or more observations (signs) in order to decide between alternative explanations searching the best one...
2017: Multidisciplinary Respiratory Medicine
Gino Soldati, Marcello Demi
In recent years, great advances have been made in the use of lung ultrasound to detect pulmonary edema and interstitial changes in the lung. However, it is clear that B-lines oversimplify the description of the physical phenomena associated with their presence. The artifactual images that ultrasounds provide in interstitial pulmonary pathology are merely the ultimate outcome of the complex interaction of a specific acoustic wave with a specific three-dimensional biological structure. This interaction lacks a solid physical interpretation of the acoustic signs to support it...
June 2017: Journal of Ultrasound
Andrea Smargiassi, Giuliana Pasciuto, Ilaria Pedicelli, Erminia Lo Greco, Mariarosaria Calvello, Riccardo Inchingolo, Gioacchino Schifino, Patrizio Capoluongo, Pasquale Patriciello, Maurizio Manno, Alfonso Cirillo, Giuseppe Maria Corbo, Gino Soldati, Ivo Iavicoli
OBJECTIVES: Exposure to asbestos fibers can lead to different lung diseases, such as pleural thickening and effusion, asbestosis, mesothelioma, and lung cancer. These diseases are expected to peak in the next few years. The aim of the study was to validate ultrasonography (US) as a diagnostic tool in the management of lung diseases in subjects with a history of occupational exposure to asbestos. METHODS: Fifty-nine retired male workers previously exposed to asbestos were enrolled in the study...
June 2017: Toxicology and Industrial Health
Erik Arbeid, Alessio Demi, Etrusca Brogi, Elisa Gori, Teresa Giusto, Gino Soldati, Luigi Vetrugno, Francesco Giunta, Francesco Forfori
BACKGROUND/AIMS: The normal lung ultrasound (US) pattern during a regular pregnancy has not been evaluated extensively in the current literature. Pregnancy-related changes in the respiratory tract affect maternal predisposition to several respiratory complications; consequently, it is important to differentiate between a physiologic pattern during pregnancy and a pathologic lung pattern, due to respiratory failure. The goal of our study was to assess the normal US lung pattern in women without known comorbidities in the last weeks of pregnancy...
2017: Gynecologic and Obstetric Investigation
Gino Soldati, Marcello Demi, Riccardo Inchingolo, Andrea Smargiassi, Libertario Demi
No abstract text is available yet for this article.
October 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Gino Soldati, Andrea Smargiassi, Riccardo Inchingolo, Sara Sher, Rosanna Nenna, Salvatore Valente, Cosimo Damiano Inchingolo, Giuseppe Maria Corbo
BACKGROUND: Echographic vertical artifacts (B-lines) in chest ultrasonography have often been associated with pathological patterns. A scientifically sound explanation of these artifacts has not yet been proposed. OBJECTIVES: The 'spongy' nature of the lung in its liquid and solid components and the changes that take place in peripheral airspace (PAS) geometry might be the key point to understanding these phenomena. METHODS: Six excised right rabbit lungs were obtained...
2014: Respiration; International Review of Thoracic Diseases
Libertario Demi, Marcello Demi, Andrea Smargiassi, Riccardo Inchingolo, Francesco Faita, Gino Soldati
BACKGROUND: Nowadays, ultrasound techniques have not gained importance in the diagnosis and monitoring of lung pathologies yet because of the high mismatch in acoustic impedance between air and intercostal tissues. However, it is evident that B-mode imaging provides important information on pulmonary tissue, although in the form of image artifacts. FINDINGS: Notwithstanding medical evidences, there exists no ultrasound-based method dedicated to the lung, hampering de facto the full exploitation of ultrasound potentials...
2014: Multidisciplinary Respiratory Medicine
Andrea Smargiassi, Riccardo Inchingolo, Gino Soldati, Roberto Copetti, Giampietro Marchetti, Alessandro Zanforlin, Rosangela Giannuzzi, Americo Testa, Stefano Nardini, Salvatore Valente
Chest ultrasonography can be a useful diagnostic tool for respiratory physicians. It can be used to complete and widen the general objective examination also in emergency situations, at the patient's bedside. The aim of this document is to promote better knowledge and more widespread use of thoracic ultrasound among respiratory physicians in Italy.This document II is focused on advanced approaches to chest ultrasonography especially in diagnosing sonographic interstitial syndrome with physical hypotheses about the genesis of vertical artifacts, differential diagnosis of cardiogenic pulmonary edema and non-cardiogenic pulmonary edema, raising diagnostic suspicion of pulmonary embolism, ultrasound characterization of lung consolidations and the use of ultrasonography to guide procedural interventions in pulmonology...
August 9, 2013: Multidisciplinary Respiratory Medicine
Alessandro Zanforlin, Rosangela Giannuzzi, Stefano Nardini, Americo Testa, Gino Soldati, Roberto Copetti, Giampietro Marchetti, Salvatore Valente, Riccardo Inchingolo, Andrea Smargiassi
Chest ultrasonography can be a useful diagnostic tool for respiratory physicians. It can be used to complete and widen the general objective examination also in emergency situations, at the patient's bedside. The aim of this document is to promote better knowledge and more widespread use of thoracic ultrasound among respiratory physicians in Italy. This document I is focused on basic knowledge of chest ultrasonography technique, physical basis, aims and characteristics, fields of application. Document I shows how chest ultrasonography can be useful to detect and monitor pleural diseases, pleural effusions and pneumothorax and how it can assess diaphragmatic kinetics and pathologies...
August 9, 2013: Multidisciplinary Respiratory Medicine
Gino Soldati, Andrea Smargiassi, Riccardo Inchingolo, Sara Sher, Salvatore Valente, Giuseppe Maria Corbo
BACKGROUND: The aim of this study is to evaluate feasibility, safety and efficacy of accessing the pleural space with the patient supine or in lateral recumbent position, under constant ultrasonic guidance along the costophrenic sinus. METHODS: All patients with pleural effusion, referred to thoracentesis or pleural drainage from February 2010 to January 2011 in two institutions, were drained either supine or in lateral recumbent position through an echomonitored cannulation of the costophrenic sinus...
2013: Multidisciplinary Respiratory Medicine
Gino Soldati, Riccardo Inchingolo, Andrea Smargiassi, Sara Sher, Rosanna Nenna, Cosimo Damiano Inchingolo, Salvatore Valente
Ultrasound (US) interstitial syndrome is a sonographic lung pattern characterized by the presence of acoustic artifacts (B-lines and white lung). The purpose of this study was to demonstrate how interstitial syndrome is determined by acoustic interactions in lungs of variable density and in healthy organs deflated to a nonphysiologic level of density. Normal rabbit lungs were studied ex vivo by US at varying known degrees of inflation, and their histologic appearances were described. In this experimental setting, US interstitial syndrome recognizes a mechanism related to tissue density or porosity...
July 2012: Ultrasound in Medicine & Biology
Giovanni Volpicelli, Mahmoud Elbarbary, Michael Blaivas, Daniel A Lichtenstein, Gebhard Mathis, Andrew W Kirkpatrick, Lawrence Melniker, Luna Gargani, Vicki E Noble, Gabriele Via, Anthony Dean, James W Tsung, Gino Soldati, Roberto Copetti, Belaid Bouhemad, Angelika Reissig, Eustachio Agricola, Jean-Jacques Rouby, Charlotte Arbelot, Andrew Liteplo, Ashot Sargsyan, Fernando Silva, Richard Hoppmann, Raoul Breitkreutz, Armin Seibel, Luca Neri, Enrico Storti, Tomislav Petrovic
BACKGROUND: The purpose of this study is to provide evidence-based and expert consensus recommendations for lung ultrasound with focus on emergency and critical care settings. METHODS: A multidisciplinary panel of 28 experts from eight countries was involved. Literature was reviewed from January 1966 to June 2011. Consensus members searched multiple databases including Pubmed, Medline, OVID, Embase, and others. The process used to develop these evidence-based recommendations involved two phases: determining the level of quality of evidence and developing the recommendation...
April 2012: Intensive Care Medicine
Americo Testa, Gino Soldati, Roberto Copetti, Rosangela Giannuzzi, Grazia Portale, Nicolò Gentiloni-Silveri
INTRODUCTION: The clinical picture of the pandemic influenza A (H1N1)v ranges from a self-limiting afebrile infection to a rapidly progressive pneumonia. Prompt diagnosis and well-timed treatment are recommended. Chest radiography (CRx) often fails to detect the early interstitial stage. The aim of this study was to evaluate the role of bedside chest ultrasonography (US) in the early management of the 2009 influenza A (H1N1)v infection. METHODS: 98 patients who arrived in the Emergency Department complaining of influenza-like symptoms were enrolled in the study...
February 17, 2012: Critical Care: the Official Journal of the Critical Care Forum
Gino Soldati, Valeria Giunta, Sara Sher, Francesca Melosi, Claudia Dini
Ultrasound interstitial syndrome is an echographic pattern of the lung characterized by the presence of multiple acoustic artifacts called "comets" or B-lines. It correlates to increase in extravascular lung water and to interstitial lung disease. From the physical and genetic point of view, the characteristics and the entity of this correlation have not yet been studied. The purpose of this study was to extrapolate past observations and demonstrate how comets or B-lines are artifactual images whose formation is linked to ultrasound interactions on discretely aerated tissues of variable density...
November 2011: Ultrasound in Medicine & Biology
Americo Testa, Gino Soldati, Rosangela Giannuzzi, Silvia Berardi, Grazia Portale, Nicolò Gentiloni Silveri
The purpose of this study was to set an effective standardized method to assess diaphragmatic kinetics by ultrasound. Forty healthy volunteers were submitted to a B- and M-mode ultrasound study using a convex transducer positioned in the subcostal anterior area for transverse scanning. Ultrasound examination was completed in 38/40 cases (95%), spending on average <10 min for examination. The resting and forced diaphragmatic excursions were 18.4 ± 7.6 and 78.8 ± 13.3 mm, respectively, unrelated to demographic or anthropometric parameters: intraobserver variability on three successive measurements resulted in 6...
January 2011: Ultrasound in Medicine & Biology
Gino Soldati, Roberto Copetti, Sara Sher
OBJECTIVE: Ultrasound lung comets (ULCs) now have an acknowledged correlation with extravascular lung water, but they present in different orders and numbers in different pathologic pulmonary entities. How these artifacts are created is not yet known, and the literature gives discordant hypotheses. Understanding their formation is the first step in understanding lung disease. The purpose of this study was to show the morphologic and genetic variability of interstitial lung disease studied with echography and thus to propose a unitary mechanism for the formation of ULCs...
February 2009: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Roberto Copetti, Gino Soldati, Paolo Copetti
BACKGROUND: Differential diagnosis between acute cardiogenic pulmonary edema (APE) and acute lung injury/acute respiratory distress syndrome (ALI/ARDS) may often be difficult. We evaluated the ability of chest sonography in the identification of characteristic pleuropulmonary signs useful in the diagnosis of ALI/ARDS and APE. METHODS: Chest sonography was performed on admission to the intensive care unit in 58 consecutive patients affected by ALI/ARDS or by acute pulmonary edema (APE)...
April 29, 2008: Cardiovascular Ultrasound
Gino Soldati, Luna Gargani, Fernando R Silva
The topic of heart failure (HF) in the emergency department is today relevant, since there are new serum markers and imaging techniques that may help in the diagnosis of this disease. Natriuretic peptides have now entered the flowchart for etiologic diagnosis in patients with acute dyspnea, when technical facilities are available. Recently, chest ultrasonography has been shown to be useful for the noninvasive assessment of extravascular lung water. Starting from this practical standpoint, we propose that simple chest ultrasonographic signs can provide a totally noninvasive characterization of pulmonary congestion in patients with HF...
March 2008: Internal and Emergency Medicine
Gino Soldati, Americo Testa, Sara Sher, Giulia Pignataro, Monica La Sala, Nicolò Gentiloni Silveri
BACKGROUND: The role of chest ultrasonography (US) in the diagnosis of pneumothorax (PTX) has been established, but how it compares with lung CT scanning in the diagnosis of radiooccult PTX and in the determination of its topographic extension has not yet been completely evaluated. OBJECTIVE: To determine the diagnostic accuracy of chest US in the emergency department (ED) in the diagnosis of occult PTX in trauma patients and to define its ability to determine PTX extension...
January 2008: Chest
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