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https://www.readbyqxmd.com/read/28376442/prevalence-of-atypical-pathogens-in-patients-with-cough-and-community-acquired-pneumonia-a-meta-analysis
#1
REVIEW
Christian Marchello, Ariella Perry Dale, Thuy Nhu Thai, Duk Soo Han, Mark H Ebell
PURPOSE: Community-acquired pneumonia (CAP), acute cough, bronchitis, and lower respiratory tract infections (LRTI) are often caused by infections with viruses or Streptococcus pneumoniae. The prevalence of atypical pathogens Mycoplasma pneumoniae, Chlamydophila pneumoniae, Legionella pneumophila, and Bordetella pertussis among patients with these illnesses in the ambulatory setting has not been previously summarized. We set out to derive prevalence information from the existing literature...
November 2016: Annals of Family Medicine
https://www.readbyqxmd.com/read/28376440/disease-course-of-lower-respiratory-tract-infection-with-a-bacterial-cause
#2
Jolien Teepe, Berna D L Broekhuizen, Katherine Loens, Christine Lammens, Margareta Ieven, Herman Goossens, Paul Little, Christopher C Butler, Samuel Coenen, Maciek Godycki-Cwirko, Theo Verheij
PURPOSE: Bacterial pathogens are assumed to cause an illness course different from that of nonbacterial causes of acute cough, but evidence is lacking. We evaluated the disease course of lower respiratory tract infection (LRTI) with a bacterial cause in adults with acute cough. METHODS: We conducted a secondary analysis of a multicenter European trial in which 2,061 adults with acute cough (28 days' duration or less) were recruited from primary care and randomized to amoxicillin or placebo...
November 2016: Annals of Family Medicine
https://www.readbyqxmd.com/read/28368089/withdrawn-surgery-for-thumb-trapeziometacarpal-joint-osteoarthritis
#3
REVIEW
Anne Wajon, Toby Vinycomb, Emma Carr, Ian Edmunds, Louise Ada
BACKGROUND: Surgery is used to treat persistent pain and dysfunction at the base of the thumb when conservative management, such as splinting, or medical management, such as oral analgesics, is no longer adequate in reducing disability and pain. This is an update of a Cochrane Review first published in 2005. OBJECTIVES: To assess the effects of different surgical techniques for trapeziometacarpal (thumb) osteoarthritis. SEARCH METHODS: We searched the following sources up to 08 August 2013: CENTRAL (The Cochrane Library 2013, Issue 8), MEDLINE (1950 to August 2013), EMBASE (1974 to August 2013), CINAHL (1982 to August 2013), Clinicaltrials...
April 3, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28361961/exposure-to-paternal-tobacco-smoking-increased-child-hospitalization-for-lower-respiratory-infections-but-not-for-other-diseases-in-vietnam
#4
Reiko Miyahara, Kensuke Takahashi, Nguyen Thi Hien Anh, Vu Dinh Thiem, Motoi Suzuki, Hiroshi Yoshino, Le Huu Tho, Hiroyuki Moriuchi, Sharon E Cox, Lay Myint Yoshida, Dang Duc Anh, Koya Ariyoshi, Michio Yasunami
Exposure to environmental tobacco smoke (ETS) is an important modifiable risk factor for child hospitalization, although its contribution is not well documented in countries where ETS due to maternal tobacco smoking is negligible. We conducted a birth cohort study of 1999 neonates between May 2009 and May 2010 in Nha Trang, Vietnam, to evaluate paternal tobacco smoking as a risk factor for infectious and non-infectious diseases. Hospitalizations during a 24-month observation period were identified using hospital records...
March 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28357706/the-burden-and-long-term-respiratory-morbidity-associated-with-respiratory-syncytial-virus-infection-in-early-childhood
#5
REVIEW
Brigitte Fauroux, Eric A F Simões, Paul A Checchia, Bosco Paes, Josep Figueras-Aloy, Paolo Manzoni, Louis Bont, Xavier Carbonell-Estrany
INTRODUCTION: The REGAL (RSV Evidence-a Geographical Archive of the Literature) series provide a comprehensive review of the published evidence in the field of respiratory syncytial virus (RSV) in Western countries over the last 20 years. The objective of this fifth publication was to determine the long-term respiratory morbidity associated with RSV lower respiratory tract infection (RSV LRTI) in early life. METHODS: A systematic review was undertaken for articles published between January 1, 1995 and December 31, 2015...
March 29, 2017: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/28350820/antibiotic-prescribing-for-acute-lower-respiratory-tract-infections-lrti-guideline-adherence-in-the-german-primary-care-setting-an-analysis-of-routine-data
#6
Eva Maria Kraus, Steffen Pelzl, Joachim Szecsenyi, Gunter Laux
OBJECTIVES: Antibiotic overprescribing in primary care has major impacts on the development of antibiotic resistance. The objective of this study is to provide insight in antibiotics prescriptions for patients suffering from cough, acute bronchitis or community acquired pneumonia in primary care. METHODS: Data from 2009 to 2013 of electronic health records of 12,880 patients in Germany were obtained from a research database. The prescription of antibiotics for acute lower respiratory tract infections was compared to the national S3 guideline cough from the German Society of General Practitioners and Family Medicine...
2017: PloS One
https://www.readbyqxmd.com/read/28333409/missed-opportunities-for-antimicrobial-stewardship-in-pre-school-children-admitted-to-hospital-with-lower-respiratory-tract-infection
#7
Tony Walls, Erika Stark, Philip Pattemore, Lance Jennings
AIM: To describe the usage of multiplex polymerase chain reaction on nasopharyngeal swab (NPS) samples in pre-school children presenting with lower respiratory tract infection (LRTI) at Christchurch Hospital, and its impact on the use of antibiotics empirically and at discharge. METHODS: This retrospective cohort study included 237 children, ages 3 months to 5 years, admitted to hospital during the winter months of 2012-2015 with a diagnosis of community-acquired LRTI...
March 23, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28325579/burden-of-healthcare-associated-infections-in-china-results-of-the-2015-point-prevalence-survey-in-dong-guan-city
#8
J Wang, J Hu, S Harbarth, D Pittet, M Zhou, W Zingg
BACKGROUND: Healthcare-associated infections (HCAIs) are a major health threat. There are few data about HCAI and antibiotic use in the People's Republic of China in the English literature. AIM: To describe and discuss the prevalence of HCAI and antibiotic use from the 2015 point prevalence survey (PPS) in Dong Guan City. METHODS: In 2015, the Dong Guan (City) Nosocomial Infection Control and Quality Improvement Centre organized its yearly PPS in the secondary and tertiary care hospitals of Dong Guan City...
February 17, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28298164/the-most-appropriate-therapeutic-strategy-for-acute-lower-respiratory-tract-infections-a-delphi-based-approach
#9
Francesco Blasi, Ercole Concia, Bruno Del Prato, Massimo Giusti, Teresita Mazzei, Barbara Polistena, Alessandro Rossi, Stefania Stefani, Andrea Novelli
Lower respiratory tract infections (LRTIs) cause high morbidity and mortality worldwide. Empiric therapy often base the choice of antibiotic treatment on antibacterial spectrum of the agent rather than on its pharmacological properties or the pathogen resistance profile. Inappropriate prescribing leads to therapeutic failure and antibiotic resistance, with increasing direct and indirect health costs. A consensus on appropriate prescribing in LRTI therapy was appraised by this Delphi exercise, based on a panel of 70 pulmonologists, coordinated by a Scientific Committee of nine experts in respiratory medical care...
March 15, 2017: Journal of Chemotherapy
https://www.readbyqxmd.com/read/28270165/clinical-and-epidemiological-profiles-including-meteorological-factors-of-low-respiratory-tract-infection-due-to-human-rhinovirus-in-hospitalized-children
#10
Yongdong Yan, Li Huang, Meijuan Wang, Yuqing Wang, Wei Ji, Canhong Zhu, Zhengrong Chen
BACKGROUND: Lower respiratory tract infection (LRTI) is a major cause of morbidity and mortality in children. Human rhinovirus (HRV) is confirmed to be associated with pediatric lower respiratory tract infection. Seasonal and meteorological factors may play a key role in the epidemiology of HRV. The purposes of this study were to investigate the frequency, seasonal distribution, and clinical characteristics of hospitalized children with LRTI caused by HRVs. In addition, associations between incidence of HRVs and meteorological factors in a subtropical region of China were discussed...
March 7, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28236418/one-year-observational-study-of-palivizumab-prophylaxis-on-infants-at-risk-for-respiratory-syncytial-virus-infection-in-latin-america
#11
Leandro Martin Castillo, Gabriela Bugarin, Juan Carlos Arias, Jairo Israel Barajas Rangel, Maria Elina Serra, Nestor Vain
OBJECTIVE: This study aims to describe real world palivizumab use and effectiveness in high-risk Latin American infants and young children. METHOD: Prospective, multicenter observational study with infants at risk for severe RSV infection who received palivizumab according to routine clinical practice. Subjects were followed for one year with monthly visits after the first dose of palivizumab. An infant was considered adherent if receiving all the expected injections or five or fewer injections within appropriate inter-dose intervals...
February 22, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28231310/breastfeeding-and-the-risk-of-respiratory-tract-infections-after-infancy-the-generation-r-study
#12
Ilse Tromp, Jessica Kiefte-de Jong, Hein Raat, Vincent Jaddoe, Oscar Franco, Albert Hofman, Johan de Jongste, Henriëtte Moll
BACKGROUND: The protection of breastfeeding against respiratory tract infections in the first year of life has often been suggested. Few studies examined the effect of breastfeeding on respiratory tract infections after infancy. OBJECTIVE: To examine the association between breastfeeding with lower respiratory tract infections (LRTI) and upper respiratory tract infections (URTI) after infancy up to 4 years of age (n = 5322). METHODS: This study was embedded in The Generation R study, a Dutch population-based prospective cohort study from fetal life until young adulthood...
2017: PloS One
https://www.readbyqxmd.com/read/28214925/missed-opportunities-in-neonatal-deaths-in-rwanda-applying-the-three-delays-model-in-a-cross-sectional-analysis-of-neonatal-death
#13
Efua Wilmot, Marcel Yotebieng, Alison Norris, Fidele Ngabo
Objective Administered in a timely manner, current evidence-based interventions could reduce neonatal deaths from infections, intrapartum injuries and complications due to prematurity. The three delays model (delay in seeking care, in arriving at a health facility, and in receiving adequate care), which has been applied to understanding maternal deaths, may be useful for understanding neonatal deaths. We assess the main causes of neonatal deaths in Rwanda and their associated delays. Methods Using a cross-sectional study design, we evaluated data from 2012 from 40 facilities in which babies were delivered...
February 18, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28208857/emergence-of-hospital-acquired-carbapenem-resistant-non-fermenters-in-teaching-institute
#14
Hariom Sharan, Neeraj Katare, Aparna Pandey, Ganesh Shivmurti Bhatambare, Trupti Bajpai
INTRODUCTION: Non-Fermenting Gram Negative Bacilli (NFGNB) are emerging now-a-days because of their tendency to colonize various surfaces and inherent resistance to commonly used disinfectants. They are responsible for multi-drug resistant hospital acquired infections. Detection of carbapenem resistance mechanisms is essential for treatment and infection control purpose as can spread to other organisms causing hospital outbreaks. AIM: To characterize non-fermenters from various clinical samples and to detect different carbapenem resistance mechanisms in meropenem resistant isolates...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28167875/locking-plate-arthrodesis-compares-favorably-with-lrti-for-thumb-trapeziometacarpal-arthrosis-early-outcomes-from-a-longitudinal-cohort-study
#15
Nikolas H Kazmers, K J Hippensteel, Ryan P Calfee, Lindley B Wall, Martin I Boyer, Charles A Goldfarb, Richard H Gelberman, Daniel A Osei
BACKGROUND: Trapeziometacarpal arthrodesis (TMA) has been complicated by nonunion and hardware failure. QUESTIONS/PURPOSES: We hypothesized that modification of the TMA technique with a locking cage plate construct would afford reliable bony union while producing greater hand function than trapeziectomy with ligament reconstruction and tendon interposition (LRTI) at early follow-up. METHODS: We enrolled 36 consecutive patients with trapeziometacapal osteoarthritis (14 TMA patients (15 thumbs), 22 LRTI patients (22 thumbs))...
February 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28164439/seasonal-changes-of-lower-respiratory-tract-infections-in-lung-transplant-recipients-during-the-first-post-transplant-year-the-hungarian-experience
#16
Zsuzsanna Kovats, Aniko Bohacs, Zoltan Sutto, Krisztina Vincze, Jozsef Lukacsovits, Gyorgy Losonczy, Veronika Müller
BACKGROUND: After lung transplantation (LuTX) a high level of immunosuppression is needed to prevent rejection of the graft. Together with earlier colonization by pathogens, immunosuppression makes recipients more susceptible to infections, especially during the first postoperative year. As seasonality of lower respiratory tract infections (LRTI) is well-known in chronic lung diseases, we assessed seasonal changes of pathogen spectrum and number of infections in the first postoperative year in LuTX recipients...
February 5, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28160900/evidence-based-practice-in-the-surgical-treatment-of-thumb-carpometacarpal-joint-arthritis
#17
Frank Yuan, Oluseyi Aliu, Kevin C Chung, Elham Mahmoudi
PURPOSE: Thumb carpometacarpal (CMC) arthritis contributes considerably to functional disability in the aging adult United States (US) population. Owing to the increasing growth in this segment of our population, its burden on health care resources will increase in the future. Variations exist in the degree of complexity and cost among different surgical treatments. We examined the national trends of the surgical treatment of thumb CMC arthritis and hypothesized that current practice patterns are not supported by evidence favoring the simpler trapeziectomy-only procedure...
February 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28149211/biomechanical-comparison-of-suture-button-suspensionplasty-and-lrti-for-basilar-thumb-arthritis
#18
Mihir J Desai, David M Brogan, Marc J Richard, Suhail K Mithani, Fraser J Leversedge, David S Ruch
Background: The purpose of this study was to compare the initial biomechanical strength of trapeziectomy and suture-button suspensionplasty (SBS) with ligament reconstruction and tendon interposition (LRTI) for thumb carpometacarpal (CMC) arthritis in a cadaveric model. Methods: Eight matched pairs of below-elbow cadaveric arms were used for this study. Each specimen was randomly assigned to either receive a trapeziectomy and LRTI (LRTI group) or trapeziectomy and SBS (SBS group). Using previously described and validated testing protocols, physiological key pinch was simulated...
December 2016: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28148246/development-of-a-respiratory-severity-score-for-hospitalized-adults-in-a-high-hiv-prevalence-setting-south-africa-2010-2011
#19
Alexander J Millman, Adena Greenbaum, Sibongile Walaza, Adam L Cohen, Michelle J Groome, Carrie Reed, Meredith McMorrow, Stefano Tempia, Marietjie Venter, Florette K Treurnicht, Shabir A Madhi, Cheryl Cohen, Ebrahim Variava
BACKGROUND: Acute lower respiratory tract infections (LRTI) are a frequent cause of hospitalization and mortality in South Africa; however, existing respiratory severity scores may underestimate mortality risk in HIV-infected adults in resource limited settings. A simple predictive clinical score for low-resource settings could aid healthcare providers in the management of patients hospitalized with LRTI. METHODS: We analyzed 1,356 LRTI hospitalizations in adults aged ≥18 years enrolled in Severe Acute Respiratory Illness (SARI) surveillance in three South African hospitals from January 2010 to December 2011...
February 2, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28124966/-a-case-of-bronchiolitis-obliterans-secondary-to-human-metapneumovirus-bronchiolitis
#20
Osman Yeşilbaş, Esra Şevketoğlu, Hasan Serdar Kıhtır, Mey Talip Petmezci, Elif Bato, Seda Balkaya, Nevin Hatipoğlu, Mert Ahmet Kuşkucu, Figen Palabıyık, Erkan Çakır
Human metapneumovirus (hMPV), formerly classified in Paramyxoviridae family is now moved into Pneumoviridae, which was described as a novel family. It causes upper and lower respiratory tract infections (LRTIs) usually in children younger than five years old. The recent epidemiological studies indicated that hMPV is the second most frequently detected virus in LRTIs of young children, following the respiratory syncytial virus (RSV). Bronchiolitis obliterans (BO) is a chronic obstructive lung disease characterized by fibrosis of the distal respiratory airways...
October 2016: Mikrobiyoloji Bülteni
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