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https://www.readbyqxmd.com/read/28214491/relationship-between-patient-reported-symptoms-limitations-in-daily-activities-and-psychological-impact-in-varicose-veins
#1
Rajiv Mallick, Brajesh Kumar Lal, Claire Daugherty
OBJECTIVE: The objective of this study was to evaluate the relationship between patient-reported symptoms, functional limitations, and psychological impact of varicose veins (VVs) vs pathophysiologic mechanism, incorporating demographic and behavioral factors. METHODS: We conducted a pooled analysis from two clinical studies (Efficacy and Safety Study of Polidocanol Injectable Foam for the Treatment of Saphenofemoral Junction Incompetence [VANISH-1] and Polidocanol Endovenous Microfoam Versus Vehicle for the Treatment of Saphenofemoral Junction Incompetence [VANISH-2]) in patients with VVs (superficial venous reflux only)...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28214489/ablation-of-the-great-saphenous-vein-with-nontumescent-n-butyl-cyanoacrylate-versus-endovenous-laser-therapy
#2
İsmail Koramaz, Helin El Kılıç, Fatih Gökalp, Macit Bitargil, Nilüfer Bektaş, Ersoy Engin, Mehmet Taşkın Egici, Ahmet Kürşat Bozkurt
OBJECTIVE: The endovenous application of n-butyl cyanoacrylate (NBCA) is a new nontumescent ablation technique for the treatment of venous insufficiency. The aim of this study was to retrospectively compare an NBCA-based ablation method with endovenous laser ablation (EVLA) for the management of incompetent great saphenous veins. METHODS: Between May 2013 and August 2014, there were 339 patients with incompetent varicose veins who were treated with either the endovenous application of NBCA (VariClose Vein Sealing System [VVSS]; Biolas, Ankara, Turkey) or EVLA...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28212914/surgery-for-deep-venous-incompetence
#3
Amy K Kuwata
No abstract text is available yet for this article.
February 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28205501/transseptal-access-with-crossing-multiple-incisions-for-improved-pedicle-control-and-septum-preservation-how-i-do-it
#4
K Omura, D Asaka, J Nayak, Y Tanaka
INTRODUCTION: Recently, the surgical management of nasal tumors has been greatly influenced by advanced endoscopic techniques. To achieve complete endoscopic resection of large obstructing nasal tumors, a sufficient corridor for adequate exposure is also required. In the Japanese language, TACMI means "master expert," and herein we describe an endoscopic technique with novel elements that we term transseptal access with crossing multiple incisions (TACMI). This approach enables a direct transseptal approach to the pedicle through tumor transposition while allowing complete septal reconstruction and stability...
February 15, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28186492/requirement-of-myomaker-mediated-stem-cell-fusion-for-skeletal-muscle-hypertrophy
#5
Qingnian Goh, Douglas P Millay
Fusion of skeletal muscle stem/progenitor cells is required for proper development and regeneration, however the significance of this process during adult muscle hypertrophy has not been explored. In response to muscle overload after synergist ablation in mice, we show that myomaker, a muscle specific membrane protein essential for myoblast fusion, is activated mainly in muscle progenitors and not myofibers. We rendered muscle progenitors fusion-incompetent through genetic deletion of myomaker in muscle stem cells and observed a complete reduction of overload-induced hypertrophy...
February 10, 2017: ELife
https://www.readbyqxmd.com/read/28182493/impostor-phenomenon-and-mental-health-the-influence-of-racial-discrimination-and-gender
#6
Donte L Bernard, Quiera M Lige, Henry A Willis, Effua E Sosoo, Enrique W Neblett
The impostor phenomenon (IP), or feelings of intellectual incompetence, reflects a maladaptive set of cognitions, which pose a significant psychological risk for African American emerging adults. In light of recent evidence suggesting that personal and sociocultural factors may influence the association between IP and psychological adjustment, this study used 2 waves of data to examine the extent to which gender and racial discrimination moderated the association between IP and indices of mental health among 157 African American college students (69% women; mean age = 18...
February 9, 2017: Journal of Counseling Psychology
https://www.readbyqxmd.com/read/28182458/combined-evaluations-of-competency-to-stand-trial-and-mental-state-at-the-time-of-the-offense-an-overlooked-methodological-consideration
#7
Lauren Kois, James M Wellbeloved-Stone, Preeti Chauhan, Janet I Warren
Combined evaluations of competency to stand trial (CST; competency) and mental state at the time of the offense (MSO; sanity) frequently co-occur. However, most research examines the 2 as discrete constructs without considering 4 potential combined evaluation outcomes: competent-sane, incompetent-sane, competent-insane, and incompetent-insane. External validity can be improved if research more closely mirrored practice. It may be incorrect to assume incompetent defendants are similar across CST-only and combined evaluations, and insane defendants are similar across MSO-only and combined evaluations...
February 9, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28176382/early-mitral-bioprosthetic-failure-secondary-to-strut-entrapment-by-suture-loop-causing-severe-valve-incompetence
#8
Haytham Elgharably, Pierre De Villiers, José L Navia
No abstract text is available yet for this article.
February 8, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28167017/hearing-sensitivity-in-adults-with-a-unilateral-cleft-lip-and-palate-after-two-stage-palatoplasty
#9
I F P M Kappen, J B S Schreinemakers, K P Q Oomen, D Bittermann, M Kon, C C Breugem, A B Mink van der Molen
OBJECTIVE: To evaluate long-term hearing and middle ear status in patients treated for a unilateral complete cleft lip and palate (UCLP) by two-stage palatoplasty. METHODS: Forty-nine UCLP patients aged 17 years and older were included in this retrospective study. Patients were invited for a multidisciplinary long-term follow-up of their treatment at a tertiary center for craniofacial surgery in the Netherlands. ENT assessment included tympanometry and pure-tone audiometry...
March 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28165760/comparison-of-acl-strain-in-the-mcl-deficient-and-mcl-reconstructed-knee-during-simulated-landing-in-a-cadaveric-model
#10
Eric J Mancini, Robert Kohen, Amanda O Esquivel, Allison M Cracchiolo, Stephen Edward Lemos
BACKGROUND: Noncontact anterior cruciate ligament (ACL) injury after valgus landing has been reported and studied biomechanically. However, the role of the medial collateral ligament (MCL) in dissipating these forces has not been fully elucidated. Purpose/Hypothesis: The purpose of this study was to investigate the role that the MCL plays in ACL strain during simulated landing. The hypothesis was that ACL strain would increase significantly in MCL-incompetent knees compared with the native knee and that reconstructing the MCL would return the values to those of the intact knee...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28161580/the-ectodomain-of-rabies-virus-glycoprotein-determines-dendritic-cell-activation
#11
Junhua Huang, Yachun Zhang, Ying Huang, Clement W Gnanadurai, Ming Zhou, Ling Zhao, Zhen F Fu
The immune evasion of wild-type (wt) rabies virus (RABV) has been attributed to its glycoprotein (G), particularly to their inefficiency to bind/enter into dendritic cells (DCs). However, the domain responsible for G-mediated DC activation is not clear. In the present study, attempts were made to map the domain(s) on the G involved in differential DC activation using laboratory-adapted and wt viruses. Recombinant RABVs with exchange in each of the structural domains such as signal peptide (sp), ectodomain (et), transmembrane domain (tm), cytoplasmic tail (ct) of the G between wt and laboratory-adapted strains were constructed...
February 1, 2017: Antiviral Research
https://www.readbyqxmd.com/read/28161523/myomaker-is-required-for-the-fusion-of-fast-twitch-myocytes-in-the-zebrafish-embryo
#12
Weibin Zhang, Sudipto Roy
During skeletal muscle development, myocytes aggregate and fuse to form multinucleated muscle fibers. Inhibition of myocyte fusion is thought to significantly derail the differentiation of functional muscle fibers. Despite the purported importance of fusion in myogenesis, in vivo studies of this process in vertebrates are rather limited. Myomaker, a multipass transmembrane protein, has been shown to be the first muscle-specific fusion protein essential for myocyte fusion in the mouse. We have generated loss-of-function alleles in zebrafish myomaker, and found that fusion of myocytes into syncytial fast-twitch muscles was significantly compromised...
February 1, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28159343/palatal-lift-prosthesis-for-bolus-transport-in-a-patient-with-dysphagia-a-clinical-report
#13
Tomohisa Ohno, Norimasa Katagiri, Ichiro Fujishima
A palatal lift prosthesis (PLP) is an intraoral device that provides lift for the soft palate. The usual purpose of a PLP is to reduce nasopharyngeal reflux and the hypernasal speech caused by velopharyngeal incompetence. However, for this patient, the main purpose was to relieve a functional blockage at the oropharyngeal isthmus by suspending the soft palate. A PLP with soft and flexible lift was applied in a patient with a traumatic brain injury and dysphagia. The PLP improved oropharyngeal bolus transit time by relieving the blockage at the oropharyngeal isthmus...
January 31, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28159002/avian-species-diversity-and-transmission-of-west-nile-virus-in-atlanta-georgia
#14
Rebecca S Levine, David L Hedeen, Meghan W Hedeen, Gabriel L Hamer, Daniel G Mead, Uriel D Kitron
BACKGROUND: The dilution effect is the reduction in vector-borne pathogen transmission associated with the presence of diverse potential host species, some of which are incompetent. It is popularized as the notion that increased biodiversity leads to decreased rates of disease. West Nile virus (WNV) is an endemic mosquito-borne virus in the United States that is maintained in a zoonotic cycle involving various avian host species. In Atlanta, Georgia, substantial WNV presence in the vector and host species has not translated into a high number of human cases...
February 3, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28149731/modified-jobe-approach-with-docking-technique-for%C3%A2-ulnar-collateral-ligament-reconstruction
#15
Daniel J Kaplan, Sergio A Glait, William E Ryan, Laith M Jazrawi
The ulnar collateral ligament (UCL) of the elbow acts as the primary restraint to valgus force experienced in the late cocking and early acceleration phases of overhead throwing. If the UCL or dynamic flexor-pronator musculature is incompetent, elbow extension and valgus torque, as seen in throwing, can result in posteromedial impingement with subsequent chondromalacia and osteophyte formation. Before the first UCL reconstruction, performed by Frank Jobe in 1974, this injury was considered career ending in overhead athletes...
December 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28147268/autonomous-camkii-activity-as-a-drug-target-for-histological-and-functional-neuroprotection-after-resuscitation-from-cardiac-arrest
#16
Guiying Deng, James E Orfila, Robert M Dietz, Myriam Moreno-Garcia, Krista M Rodgers, Steve J Coultrap, Nidia Quillinan, Richard J Traystman, K Ulrich Bayer, Paco S Herson
The Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is a major mediator of physiological glutamate signaling, but its role in pathological glutamate signaling (excitotoxicity) remains less clear, with indications for both neuro-toxic and neuro-protective functions. Here, the role of CaMKII in ischemic injury is assessed utilizing our mouse model of cardiac arrest and cardiopulmonary resuscitation (CA/CPR). CaMKII inhibition (with tatCN21 or tatCN19o) at clinically relevant time points (30 min after resuscitation) greatly reduces neuronal injury...
January 31, 2017: Cell Reports
https://www.readbyqxmd.com/read/28143800/right-ventricular-outflow-tract-endocarditis-caused-by-brucellosis
#17
Feridoun Sabzi, Aghighe Heidari, Reza Faraji
Right-ventricular outflow tract (RVOT) endocarditis is a very rare presentation of right-sided infective endocarditis (RSIE) by brucellosis. RSIE occurs most commonly in immune-suppressed cases and illicit drug abuser. The patients with RSIE and an incompetent immune system usually have a prosthetic foreign body in blood circulation such as catheter, pacemakers, or central venous lines and may be accompanied with tricuspid or pulmonary valve dysfunction. The most common site for RSIE is the tricuspid valve...
January 29, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28140599/bi-molecular-photo-induced-electron-transfer-in-static-quenching-regime-illustration-of-marcus-inversion-in-micelle
#18
Puspal Mukherjee, Aritra Das, Arunava Sengupta, Pratik Sen
Ultrafast bimolecular photoinduced electron transfer (PET) between six coumarin dyes and four viologen molecules in the stern layer of sodium dodecyl sulfate micelle have been studied using femtosecond broadband transient absorption spectroscopy and femtosecond fluorescence up-conversion spectroscopy over a broad reaction exergonicity (〖∆G〗^0). Emanating the formation of radical cation intermediates of viologen molecules using the transient absorption and the fast decay component of coumarins using the fluorescence up-conversion studies the forward bi-molecular electron transfer rate (k_et) have been measured with high accuracy...
January 31, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28139903/endovenous-laser-ablation-in-patients-with-severe-primary-chronic-venous-insufficiency
#19
Vladimir Starodubtsev, Mikhail Lukyanenko, Andrey Karpenko, Pavel Ignatenko
BACKGROUND: The aim of study was to estimate the safety and efficacy of using laser wavelength of 1560 nm with the foam sclerotherapy (FS) of varicose veins (VVs) for the treatment of severe primary chronic venous insufficiency (CVI, C4-C6) in patients with different diameters of the proximal segment (DPS) of the great saphenous vein (GSV). METHODS: We have separated the patients into two groups depending on the size of GSV: group 1 (281 cases; DPS of GSV less than 15 mm) and group 2 (210 cases; DPS of GSV more than 15 mm)...
January 31, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28139506/reproductive-outcome-of-transcervical-uterine-incision-in-unicornuate-uterus
#20
En-Lan Xia, Tin-Chiu Li, Sze-Ngar Sylvia Choi, Qiao-Yun Zhou
BACKGROUND: The pregnancy outcome of the unicornuate uterus is associated with an increased risk of miscarriage, cervical incompetence, and a number of obstetric complications. However, at present, there is no accepted treatment method for women with unicornuate uterus, other than expectant measures. The aim of this study was to evaluate the reproductive outcome of transcervical uterine incision (TCUI) in patients with unicornuate uterus. METHODS: Thirty-three patients with unicornuate uterus presented to our tertiary center for infertility or miscarriage...
2017: Chinese Medical Journal
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