keyword
https://read.qxmd.com/read/38544888/influence-of-convective-heat-transfer-coefficients-on-thermal-behaviour-of-a-lithium-ion-cell-a-numerical-study
#1
JOURNAL ARTICLE
Uğur Morali
In the current study, the impact of C-ratio, convective heat transfer coefficient, and free stream temperature on the maximal cell temperature and temperature uniformity was computationally and statistically examined. Results revealed that the free stream temperature was the main influential factor for the maximal cell temperature for both natural and forced convection conditions while the C-ratio was the most effective parameter for the temperature uniformity for both natural and forced convections. On the other hand, the contribution of the free stream temperature to the maximum battery temperature increased from 63% to 94% when the conditions were changed from natural convection to forced convection...
2024: Turkish Journal of Chemistry
https://read.qxmd.com/read/38544098/on-the-search-for-potentially-anomalous-traces-of-cosmic-ray-particles-in-images-acquired-by-cmos-detectors-for-a-continuous-stream-of-emerging-observational-data
#2
JOURNAL ARTICLE
Marcin Piekarczyk, Tomasz Hachaj
In this paper we propose the method for detecting potential anomalous cosmic ray particle tracks in big data image dataset acquired by Complementary Metal-Oxide-Semiconductors (CMOS). Those sensors are part of scientific infrastructure of Cosmic Ray Extremely Distributed Observatory (CREDO). The use of Incremental PCA (Principal Components Analysis) allowed approximation of loadings which might be updated at runtime. Incremental PCA with Sequential Karhunen-Loeve Transform results with almost identical embedding as basic PCA...
March 13, 2024: Sensors
https://read.qxmd.com/read/38540940/production-of-polyhydroxyalkanoates-for-biodegradable-food-packaging-applications-using-haloferax-mediterranei-and-agrifood-wastes
#3
REVIEW
Lorena Atarés, Amparo Chiralt, Chelo González-Martínez, Maria Vargas
Polyhydroxyalkanoates (PHAs) are high-value biodegradable polyesters with thermoplastic properties used in the manufacturing of different products such as packaging films. PHAs have gained much attention from researchers and industry because of their biobased nature and appropriate features, similar to conventional synthetic plastics. This review aims to discuss some of the recent solutions to challenges associated with PHA production. The implementation of a cost-effective process is presented by following different strategies, such as the use of inexpensive carbon sources, the selection of high-producing microorganisms, and the functionalization of the final materials to make them suitable for food packaging applications, among others...
March 20, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38539571/incidence-of-catheter-associated-bloodstream-infections-in-stem-cell-recipients-should-we-be-piccy
#4
JOURNAL ARTICLE
Sławomir Milczarek, Piotr Kulig, Oliwia Piotrowska, Alina Zuchmańska, Ewa Wilk-Milczarek, Bogusław Machaliński
The management of patients undergoing HSCT requires a multipurpose central venous catheter. Peripheral catheters (PCs), such as peripherally inserted central catheters (PICCs) and MidLine catheters (MLCs), appear to be adequate vascular catheters to be used for stem cell infusion, although their utilization in this indication is not yet common. We analyzed the infectious complications such as blood stream infection (BSI), febrile neutropenia (FN) and central line-associated bloodstream infection (CLBSI) in patients undergoing stem cell infusion through PC and conventionally inserted central catchers (CICCs), and evaluated their impacts on transplantation outcomes...
March 21, 2024: Cancers
https://read.qxmd.com/read/38538638/a-time-correlated-single-photon-counting-spad-array-camera-with-a-bespoke-data-processing-algorithm-for-lightsheet-fluorescence-lifetime-imaging-flim-and-flim-videos
#5
JOURNAL ARTICLE
Jakub Nedbal, Francesco Mattioli Della Rocca, Iveta T Ivanova, Andrew Allan, Jeremy Graham, Richard Walker, Robert K Henderson, Klaus Suhling
A wide-field microscope with epi-fluorescence and selective plane illumination was combined with a single-photon avalanche diode (SPAD) array camera to enable live-cell fluorescence lifetime imaging (FLIM) using time-correlated single-photon counting (TCSPC). The camera sensor comprised of <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mtext>192</mml:mtext> <mml:mo>×</mml:mo> <mml:mtext>128</mml:mtext></mml:mrow> </mml:math> pixels, each integrating a single SPAD and a time-to-digital converter...
March 27, 2024: Scientific Reports
https://read.qxmd.com/read/38534558/the-nitrogen-content-in-the-fruiting-body-and-mycelium-of-pleurotus-ostreatus-and-its-utilization-as-a-medium-component-in-thraustochytrid-fermentation
#6
JOURNAL ARTICLE
Lina Schütte, Katharina Hausmann, Christoph Schwarz, Franziska Ersoy, Ralf G Berger
Following the idea of a circular bioeconomy, the use of side streams as substitutes for cultivation media (components) in bioprocesses would mean an enormous economic and ecological advantage. Costly compounds in conventional media for the production of the triterpene squalene in thraustochytrids are the main carbon source and complex nitrogen sources. Among other side streams examined, extracts from the spent mycelium of the basidiomycete Pleurotus ostreatus were best-suited to acting as alternative nitrogen sources in cultivation media for thraustochytrids...
March 16, 2024: Bioengineering
https://read.qxmd.com/read/38530728/production-of-targeted-estrone-liposomes-using-a-herringbone-micromixer
#7
JOURNAL ARTICLE
Mohamed Agam, Vinod Paul, Mohamed Abdelgawad, Ghaleb Husseini
Liposomes are spherical vesicles formed from bilayer lipid membranes that are extensively used in targeted drug delivery as nanocarriers to deliver therapeutic reagents to specific tissues and organs in the body. Recently, we have reported using estrone as an endogenous ligand on doxorubicin-encapsulating liposomes to target estrogen receptor (E.R.)-positive breast cancer cells. Estrone liposomes were synthesized using the thin-film hydration method, which is a long, arduous, and multistep process. Here, we report using a herringbone micromixer to synthesize estrone liposomes in a simple and rapid manner...
March 26, 2024: IEEE Transactions on Nanobioscience
https://read.qxmd.com/read/38530489/phenol-biodegradation-using-bio-filter-tower-packed-column-with-immobilized-bacterial-consortium-a-batch-test-study
#8
JOURNAL ARTICLE
Preeti Sachan, Athar Hussain, Sangeeta Madan, Utkarsh Singh, Manjeeta Priyadarshi
The effluents from pulp and paper manufacturing industries contain high concentrations of phenol, which when discharged directly into surface water streams, increases the biological oxygen demand (BOD) and chemical oxygen demand (COD). In this study, two dominant bacteria SP-4 and SP-8 were isolated from the effluent emanating with a pulp and paper industry. The selected phenol-degrading isolates were identified as Staphylococcus sp. and Staphylococcus sciuri respectively by using nucleotide sequence alignment and phylogenetic analysis of 16 S rRNA regions of the genome...
March 26, 2024: Biodegradation
https://read.qxmd.com/read/38522356/histological-changes-in-the-olfactory-bulb-and-rostral-migratory-stream-due-to-interruption-of-olfactory-input
#9
JOURNAL ARTICLE
Yukari Nakamura, Takaki Miwa, Hideaki Shiga, Hiromi Sakata, Daichi Shigeta, Toshihisa Hatta
OBJECTIVE: Periglomerular and granule cells in the adult mammalian olfactory bulb modulate olfactory signal transmission. These cells originate from the subventricular zone, migrate to the olfactory bulb via the Rostral Migratory Stream (RMS), and differentiate into mature cells within the olfactory bulb throughout postnatal life. While the regulation of neuroblast development is known to be affected by external stimuli, there is a lack of information concerning changes that occur during the recovery process after injury caused by external stimuli...
March 23, 2024: Auris, Nasus, Larynx
https://read.qxmd.com/read/38518224/co-2-electrolyzers
#10
REVIEW
Colin P O'Brien, Rui Kai Miao, Ali Shayesteh Zeraati, Geonhui Lee, Edward H Sargent, David Sinton
CO2 electrolyzers have progressed rapidly in energy efficiency and catalyst selectivity toward valuable chemical feedstocks and fuels, such as syngas, ethylene, ethanol, and methane. However, each component within these complex systems influences the overall performance, and the further advances needed to realize commercialization will require an approach that considers the whole process, with the electrochemical cell at the center. Beyond the cell boundaries, the electrolyzer must integrate with upstream CO2 feeds and downstream separation processes in a way that minimizes overall product energy intensity and presents viable use cases...
March 22, 2024: Chemical Reviews
https://read.qxmd.com/read/38508554/circular-economyeast-saccharomyces-cerevisiae-as-a-sustainable-source-of-glucans-and-its-safety-for-skincare-application
#11
JOURNAL ARTICLE
Pedro Sousa, Diana Tavares-Valente, Carla F Pereira, Inês Pinto-Ribeiro, João Azevedo-Silva, Raquel Madureira, Óscar L Ramos, Manuela Pintado, João Fernandes, Manuela Amorim
Glucans, a polysaccharide naturally present in the yeast cell wall that can be obtained from side streams generated during the fermentation process, have gained increasing attention for their potential as a skin ingredient. Therefore, this study focused on the extraction method to isolate and purify water-insoluble glucans from two different Saccharomyces cerevisiae strains: an engineered strain obtained from spent yeast in an industrial fermentation process and a wild strain produced through lab-scale fermentation...
March 18, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38508541/differential-expression-of-immune-related-biomarkers-in-primary-cultures-from-atlantic-salmon-salmo-salar-exposed-to-processed-paecilomyces-variotii-with-or-without-inactivated-moritella-viscosa
#12
JOURNAL ARTICLE
Dominic D Mensah, Byron Morales-Lange, Margareth Øverland, Kartik Baruah, Liv Torunn Mydland
Paecilomyces variotii (a filamentous fungus), is a promising novel protein source in fish feeds due to its high nutritional value. Also, P. variotii has Microbe-Associated Molecular Patterns (MAMPs) such as glucans and nucleic acids that could modulate the host's immune response. To understand the potential bioactive properties of this fungus in Atlantic salmon (Salmo salar), our study was conducted to evaluate the gene expression of immune-related biomarkers (e.g., cytokines, effector molecules and receptors) on primary cultures from salmon head kidney (HKLs) and spleen leukocytes (SLs) exposed to either UV inactivated or fractions from P...
March 18, 2024: Fish & Shellfish Immunology
https://read.qxmd.com/read/38498195/msspl12-is-a-positive-regulator-in-alfalfa-medicago-sativa-l-salt-tolerance
#13
JOURNAL ARTICLE
Shiwen Lin, Jie Yang, Yanrong Liu, Wanjun Zhang
Over expression of MsSPL12 improved alfalfa salt tolerance by reducing Na+  accumulation and increasing antioxidant enzyme activity and regulating down-stream gene expression. Improvement of salt tolerance is one of the major goals in alfalfa breeding. Here, we demonstrated that MsSPL12, an alfalfa transcription factor gene highly expressed in the stem cells, plays a positive role in alfalfa salt tolerance. MsSPL12 is localized in the nucleus and shows transcriptional activity in the presence of its C-terminus...
March 18, 2024: Plant Cell Reports
https://read.qxmd.com/read/38493187/beyond-the-microcirculation-sequestration-of-infected-red-blood-cells-and-reduced-flow-in-large-draining-veins-in-experimental-cerebral-malaria
#14
JOURNAL ARTICLE
A M Oelschlegel, R Bhattacharjee, P Wenk, K Harit, H-J Rothkötter, S P Koch, P Boehm-Sturm, K Matuschewski, E Budinger, D Schlüter, J Goldschmidt, G Nishanth
Sequestration of infected red blood cells (iRBCs) in the microcirculation is a hallmark of cerebral malaria (CM) in post-mortem human brains. It remains controversial how this might be linked to the different disease manifestations, in particular brain swelling leading to brain herniation and death. The main hypotheses focus on iRBC-triggered inflammation and mechanical obstruction of blood flow. Here, we test these hypotheses using murine models of experimental CM (ECM), SPECT-imaging of radiolabeled iRBCs and cerebral perfusion, MR-angiography, q-PCR, and immunohistochemistry...
March 16, 2024: Nature Communications
https://read.qxmd.com/read/38493086/engineering-saccharomyces-cerevisiae-for-targeted-hydrolysis-and-fermentation-of-glucuronoxylan-through-crispr-cas9-genome-editing
#15
JOURNAL ARTICLE
Jonas L Ravn, João H C Manfrão-Netto, Jana B Schaubeder, Luca Torello Pianale, Stefan Spirk, Iván F Ciklic, Cecilia Geijer
BACKGROUND: The abundance of glucuronoxylan (GX) in agricultural and forestry residual side streams positions it as a promising feedstock for microbial conversion into valuable compounds. By engineering strains of the widely employed cell factory Saccharomyces cerevisiae with the ability to directly hydrolyze and ferment GX polymers, we can avoid the need for harsh chemical pretreatments and costly enzymatic hydrolysis steps prior to fermentation. However, for an economically viable bioproduction process, the engineered strains must efficiently express and secrete enzymes that act in synergy to hydrolyze the targeted polymers...
March 16, 2024: Microbial Cell Factories
https://read.qxmd.com/read/38492797/utilizing-siamese-4d-alznet-and-transfer-learning-to-identify-stages-of-alzheimer-s-disease
#16
JOURNAL ARTICLE
Atif Mehmood, Farah Shahid, Rizwan Khan, Mostafa M Ibrahim, Zhonglong Zheng
Alzheimer's disease (AD) is the general form of dementia, leading to a progressive neurological disorder characterized by memory loss due to brain cell damage. Artificial Intelligence (AI) assists in the early identification and prediction of AD patients, determining future risks and benefits for radiologists and doctors to save time and cost. Since deep learning (DL) approaches work well with massive datasets and have recently become helpful for AD detection, there remains an area for improvement in automating detection performance...
March 14, 2024: Neuroscience
https://read.qxmd.com/read/38489084/hawthorn-fruit-crataegus-spp-polysaccharides-exhibit-immunomodulatory-activity-on-macrophages-via-tlr4-nf-%C3%AE%C2%BAb-signaling-activation
#17
JOURNAL ARTICLE
Qiang Liao, Yanan He, Chenxuan Wu, Zhiyang Deng, Jun Liu
The immunostimulatory effects and the involved molecular mechanisms of polysaccharides from hawthorn fruit (Crataegus spp.) have not been well understood. In this study, the chemical composition, monosaccharide composition, uronic acid content, and structural features of hawthorn fruit polysaccharides (HFP) and the two collected fractions were analyzed. Both AF1-2 and AF2 have pectic-like structural features rich in galacturonic acid. AF2 showed superior proinflammatory effects on macrophages which significantly increased the secretion of pro-inflammatory cytokines interleukin-1β, interleukin-6, and tumor necrosis factor-α, but not AF1-2...
March 15, 2024: Plant Foods for Human Nutrition
https://read.qxmd.com/read/38483490/phytoremediation-capability-of-anabaena-sp-for-high-organic-and-chromium-loaded-wastewater-in-membrane-bioreactors
#18
JOURNAL ARTICLE
Priyankari Bhattacharya, Subhadip Jana, Sathi Banerjee
The efficiency of Anabaena sp. was analyzed for the phytoremediation of wastewater loaded with organic matter and heavy metals like chromium. Simulated wastewater was contaminated with chromium. A side-stream membrane bioreactor was used for the treatment of wastewater. A feed tank of 20 L capacity was used with a stirring arrangement. A ceramic microfiltration membrane composed of clay and alumina was obtained from Johnson & Johnson. The removal efficiency of chemical oxygen demand, biochemical oxygen demand, and chromium was evaluated...
March 2024: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://read.qxmd.com/read/38482747/cell-free-dna-screening-for-single-gene-disorders
#19
JOURNAL ARTICLE
Brighton S Goodhue, Sky E Danity, Neeta Vora, Jeffrey A Kuller, Matthew R Grace
IMPORTANCE: In pregnancy, cell-free DNA (cfDNA) represents short fragments of placental DNA released into the maternal blood stream through natural cell death. Noninvasive prenatal screening with cfDNA is commonly used in pregnancy to screen for common aneuploidies. This technology continues to evolve, and laboratories now offer cfDNA screening for single-gene disorders. OBJECTIVE: This article aims to review cfDNA screening for single-gene disorders including the technology, current syndromes for which screening may be offered, limitations, and current recommendations...
March 2024: Obstetrical & Gynecological Survey
https://read.qxmd.com/read/38480471/identification-of-a-new-gregarine-parasite-associated-with-mass-mortality-events-of-freshwater-pearl-mussels-margaritifera-margaritifera-in-sweden
#20
JOURNAL ARTICLE
Anders Alfjorden, Ioana Onut-Brännström, Niklas Wengström, Arni Kristmundsson, Mahwash Jamy, B David Persson, Fabien Burki
Freshwater bivalves play key ecological roles in lakes and rivers, largely contributing to healthy ecosystems. The freshwater pearl mussel, Margaritifera margaritifera, is found in Europe and on the East coast of North America. Once common in oxygenated streams, M. margaritifera is rapidly declining and consequently assessed as a threatened species worldwide. Deterioration of water quality has been considered the main factor for the mass mortality events affecting this species. Yet, the role of parasitic infections has not been investigated...
March 13, 2024: Journal of Eukaryotic Microbiology
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