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memory, fenugreek

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https://www.readbyqxmd.com/read/27893738/fenugreek-seed-powder-nullified-aluminium-chloride-induced-memory-loss-biochemical-changes-a%C3%AE-burden-and-apoptosis-via-regulating-akt-gsk3%C3%AE-signaling-pathway
#1
Asokan Prema, Arokiasamy Justin Thenmozhi, Thamilarasan Manivasagam, Musthafa Mohamed Essa, Mohammed D Akbar, Mohammed Akbar
Alzheimer's disease (AD) is the most common form of dementia that mainly affects the cognitive functions of the aged populations. Trigonella foenum-graecum (L.) (fenugreek), a traditionally well utilized medicinal plant ubiquitously used as one of the main food additive worldwide, is known to have numerous beneficial health effects. Fenugreek seed extract could be able to inhibit the activity of acetylcholinesterase (AChE), a key enzyme involved in the pathogenesis of AD, and further shown to have anti-parkinsonic effect...
2016: PloS One
https://www.readbyqxmd.com/read/22680628/trigonelline-a-plant-alkaloid-with-therapeutic-potential-for-diabetes-and-central-nervous-system-disease
#2
REVIEW
J Zhou, L Chan, S Zhou
There is evidence that Trigonella foenum-graecum L. (fenugreek), a traditional Chinese herb, and its components are beneficial in the prevention and treatment of diabetes and central nervous system disease. The pharmacological activities of trigonelline, a major alkaloid component of fenugreek, have been more thoroughly evaluated than fenugreek's other components, especially with regard to diabetes and central nervous system disease. Trigonelline has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and it has been shown to reduce diabetic auditory neuropathy and platelet aggregation...
2012: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/19576740/acetylcholinesterase-enzyme-inhibitory-potential-of-standardized-extract-of-trigonella-foenum-graecum-l-and-its-constituents
#3
N Satheeshkumar, Pulok K Mukherjee, S Bhadra, B P Saha
Ethno pharmacological approach has provided several leads to identify potential new drugs from plant sources, including those for memory disorders. Acetylcholinesterase inhibitors (AChEI) give a symptomatic relief to some of the clinical manifestations of the disease. The main objective of this study is to standardize the extract of Trigonella foenum graecum L with trigonelline by HPTLC method and determine the in vitro AChE inhibitory activity of Trigonella foenum graecum L and its constituents using galanthamine as a reference...
March 2010: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
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