Miguel Rodríguez-Rubio, Juan J Menéndez-Suso, Carmen Cámara-Hijón, Miguel Río-García, María Laplaza-González, Irene Amores-Hernández, María P Romero-Gómez, Elena Álvarez-Rojas, Diana Salas-Mera, Eduardo López-Granados, Pedro de la Oliva
The multisystem inflammatory syndrome in children (MIS-C) is a novel and concerning entity related to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection. Although MIS-C has been the subject of intensive research efforts, its pathophysiology and optimal treatment remain elusive. We studied the clinical features, laboratory findings, and immunoinflammatory profiles of seven children prospectively admitted to a pediatric intensive care unit (PICU) during the first wave of the pandemic. All patients had immunoglobulin (Ig)-G against SARS-CoV-2, four of seven patients had both IgM and IgG, and in one of the 7 SARS-CoV-2 was detected in a respiratory sample...
September 2022: Journal of Pediatric Intensive Care