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DTI brainstem stroke

Leszek Lombarski, Przemysław Kunert, Marcin Skawiński, Marek Prokopienko, Zbigniew Lewandowski, Andrzej Marchel
OBJECTIVE: Vertebral artery medulla compression syndrome (VAMCS) is a very rare condition manifesting as different neurological focal deficits. The case of a 36-year-old male with symptomatic brainstem compression by vertebral artery (VA) treated by means of microvascular decompression (MVD) and a review of the literature is presented. CASE REPORT: On admission, a 36-year-old patient presented with hypoalgesia, hypothermesthesia and hemiparesis on the left side...
March 17, 2018: Neurologia i Neurochirurgia Polska
Charles S Cox, Robert A Hetz, George P Liao, Benjamin M Aertker, Linda Ewing-Cobbs, Jenifer Juranek, Sean I Savitz, Margaret L Jackson, Anna M Romanowska-Pawliczek, Fabio Triolo, Pramod K Dash, Claudia Pedroza, Dean A Lee, Laura Worth, Imoigele P Aisiku, Huimahn A Choi, John B Holcomb, Ryan S Kitagawa
Preclinical studies using bone marrow derived cells to treat traumatic brain injury have demonstrated efficacy in terms of blood-brain barrier preservation, neurogenesis, and functional outcomes. Phase 1 clinical trials using bone marrow mononuclear cells infused intravenously in children with severe traumatic brain injury demonstrated safety and potentially a central nervous system structural preservation treatment effect. This study sought to confirm the safety, logistic feasibility, and potential treatment effect size of structural preservation/inflammatory biomarker mitigation in adults to guide Phase 2 clinical trial design...
April 2017: Stem Cells
Påvel G Lindberg, Djamel Bensmail, Bernard Bussel, Marc A Maier, Antoine Feydy
BACKGROUND AND PURPOSE: wallerian degeneration (WD) in descending motor tracts after stroke is described at the level of the internal capsule and the brainstem. We investigated whether diffusion tensor imaging (DTI) can detect degeneration in the lateral cervical spinal cord after stroke. METHODS: DTI at 1.5 T of the cervical spinal cord was performed in 4 chronic hemiparetic patients after ischemic stroke. Stroke lesions included the corticospinal tract. DTI was also performed in 12 healthy controls...
January 2011: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
Weihong Zhang, Xin Li, Jiangyang Zhang, Andreas Luft, Daniel F Hanley, Peter van Zijl, Michael I Miller, Laurent Younes, Susumu Mori
Although DTI can provide detailed information about white matter anatomy, it is not yet straightforward enough to quantify the anatomical information it visualizes. In this study, we developed and tested a new tool to perform brain normalization and voxel-based analysis of DTI data. For the normalization part, manually placed landmarks ensured that the visualized white matter tracts were well-registered among the populations. A standard landmark set in ICBM-152 space and an interface to remap them to subject data were integrated in the procedure...
February 1, 2009: NeuroImage
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