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Perimetry

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https://www.readbyqxmd.com/read/28056057/flat-anterior-chamber-after-trabeculectomy-in-secondary-angle-closure-glaucoma-with-best1-gene-mutation-case-series
#1
Yimin Zhong, Xinxing Guo, Hui Xiao, Jingyi Luo, Chengguo Zuo, Xiaobo Huang, Jingjing Huang, Lan Mi, Qingjiong Zhang, Xing Liu
PURPOSE: Trabeculectomy has been regarded as a mainstay of initial treatment in eyes of angle closure glaucoma (ACG) with peripheral anterior synechia > 180° in the Chinese population while its efficacy in secondary ACG with BEST1 gene mutation remains unclear. We set out to investigate the treatment outcome of trabeculectomy for secondary ACG in a group of patients with autosomal recessive bestrophinopathy (ARB). METHODS: In this retrospective case series study, 8 secondary ACG patients with ARB and their 4 recruited family members underwent a thorough ophthalmic examination including best-corrected visual acuity, Goldmann applanation tonometry, gonioscopy, and fundus examinations...
2017: PloS One
https://www.readbyqxmd.com/read/28039596/optic-neuritis-secondary-to-antiandrogen-therapy
#2
REVIEW
Á Ní Mhéalóid, G Cunniffe
BACKGROUND: Optic neuropathy is a disorder characterised by dysfunction or destruction of the optic nerve tissues. Acquired causes include interruption in the blood supply, nutritional deficiency, compression by a tumour or aneurysm, trauma, and toxic types (Ambizas and Patel In US Pharm 36(4):HS2-HS6, 1). Drug-induced optic neuropathy is of the toxic type and can be defined as a clinical syndrome characterised by papillomacular bundle damage, central, or cecocentral scotoma, and reduced colour vision (Ambizas and Patel In US Pharm 36(4):HS2-HS6, 2011; Sharma and Sharma In Indian J Ophthalmol 59(2):137-141, 2)...
December 30, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28032805/nerve-fiber-layer-thickness-and-characteristics-associated-with-glaucoma-in-community-living-older-adults-prelude-to-a-screening-trial
#3
Barbara E K Klein, Chris A Johnson, Stacy M Meuer, Kyungmoo Lee, Andreas Wahle, Kristine E Lee, Amruta Kulkarni, Milan Sonka, Michael D Abràmoff, Ronald Klein
PURPOSE: To examine the associations of nerve fiber layer (NFL) thickness with other ocular characteristics in older adults. METHODS: Participants in the Beaver Dam Eye Study (2008-2010) underwent spectral domain optical coherence tomography (SD-OCT) scans of the optic nerve head, imaging of optic discs, frequency doubling technology (FDT) perimetry, measurement of intraocular pressure (IOP), and an interview concerning their history of glaucoma and use of drops to lower eye pressure...
December 29, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28012881/improving-our-understanding-and-detection-of-glaucomatous-damage-an-approach-based-upon-optical-coherence-tomography-oct
#4
REVIEW
Donald C Hood
Although ophthalmologists are becoming increasingly reliant upon optical coherence tomography (OCT), clinicians who care for glaucoma patients are not taking full advantage of the potential of this powerful technology. First, we ask, how would one describe the nature of glaucomatous damage if only OCT scans were available? In particular, a schematic model of glaucomatous damage is developed in section 2, and the nature of glaucomatous damage seen on OCT scans described in the context of this model in section 3...
December 22, 2016: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28009776/bilateral-occipital-pole-hypertensive-stroke-diagnosed-with-macular-integrity-assessment-maia-microperimetry
#5
Sundeep K Kasi, Abtin Shahlaee, Murtaza K Adam, David S Ehmann, Arunan Sivalingam
PURPOSE: To describe the utility of microperimetry testing in the diagnosis of a bilateral occipital stroke. METHODS: Retrospective case report. RESULTS: A 57-year-old male with hypertension presented with complaints of bilateral blurred central vision and bilateral hypertensive retinopathy with cotton-wool spots. Automated perimetry demonstrated a central scotoma in both eyes that did not respect the vertical midline; however, microperimetry testing revealed a bilateral homonymous hemianopia that suggested cerebrovascular disease which was subsequently confirmed with magnetic resonance imaging...
January 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28009405/fulminant-idiopathic-intracranial-hypertension-and-venous-stasis-retinopathy-resulting-in-severe-bilateral-visual-impairment
#6
Alexander Voldman, Breanna Durbin, John Nguyen, Brian Ellis, Monique Leys
PURPOSE: To report a complicated case of fulminant idiopathic intracranial hypertension and concomitant venous stasis retinopathy leading to postpapilledema optic atrophy. METHODS: Case report. RESULTS: A 34-year-old morbidly obese woman with a history of idiopathic intracranial hypertension (IIH) presented with a 1-month history of bilateral vision loss, diplopia, and left eye pain after being lost to follow-up for 6 years. Fundus examination revealed florid papilledema with venous tortuosity bilaterally...
December 6, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28005674/didanosine-retinal-toxicity
#7
Sara J Haug, Robert W Wong, Shelley Day, Netan Choudhry, Scott Sneed, Pradeep Prasad, Sarah Read, Richard H McDonald, Anita Agarwal, Janet Davis, David Sarraf
PURPOSE: To report nine new cases of retinal degeneration secondary to didanosine toxicity and to summarize the previously reported cases in the literature. METHODS: This was a multicenter, retrospective, observational case study from seven institutions. Medical records of patients who demonstrated well-demarcated severe midperipheral chorioretinal degeneration and who were previously treated with didanosine therapy were collected and the following information was reviewed: age, gender, medical history, detailed medication history including current and previous antiretroviral use, ocular and retinal examination findings, and multimodal imaging findings with optical coherence tomography, fundus photography, wide-field fundus autofluorescence, and wide-field fluorescein angiography...
December 2016: Retina
https://www.readbyqxmd.com/read/27998453/-clinical-features-of-neurosyphilis-with-optic-neuritis-as-an-initial-finding
#8
S S Cao, H Y Li, Q G Xu, S Y Tan, S H Wei
Objective: To study the characteristics of neurosyphilis with optic neuritis as an initial finding. Methods: Retrospective analysis of clinical data and laboratory testing results of 16 cases (27 eyes) with optic neuritis as an initial finding of neurosyphilis from October 2010 to March 2015 in General Hospital of People's Liberation Army was made. Results: Six-teen patients (12 males, 4 females) were collected, the median age of patients was 47 (range 33 to 65) years ,the mean age was (49.63±9.05) years. Treponema pallidum particle agglutination assay (TPPA) analysis was positive in all of the patients and rapid plasma reagin (RPR) test was positive in 14 patients (2 patients did not test)...
December 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27997924/test-retest-reliability-of-scotopic-and-mesopic-fundus-controlled-perimetry-using-a-modified-maia-macular-integrity-assessment-in-normal-eyes
#9
Maximilian Pfau, Moritz Lindner, Monika Fleckenstein, Robert P Finger, Gary S Rubin, Wolf M Harmening, Marco U Morales, Frank G Holz, Steffen Schmitz-Valckenberg
PURPOSE: To assess the intrasession test-retest reliability of scotopic cyan and scotopic red fundus-controlled perimetry (FCP) in normal subjects using a modified MAIA "microperimeter" (macular integrity assessment) device. METHODS: Forty-seven normal eyes of 30 subjects (aged 33.8 years) underwent duplicate mesopic (achromatic stimuli, 400-800 nm), scotopic cyan (505 nm), and scotopic red (627 nm) FCP, using a grid of 49 stimuli over 14° of the central retina...
December 21, 2016: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/27986385/natural-history-of-the-central-structural-abnormalities-in-choroideremia-a-prospective-cross-sectional-study
#10
Tomas S Aleman, Grace Han, Leona W Serrano, Nicole M Fuerst, Emily S Charlson, Denise J Pearson, Daniel C Chung, Anastasia Traband, Wei Pan, Gui-Shuang Ying, Jean Bennett, Albert M Maguire, Jessica I W Morgan
PURPOSE: To describe in detail the central retinal structure of a large group of patients with choroideremia (CHM). DESIGN: A prospective, cross-sectional, descriptive study. PARTICIPANTS: Patients (n = 97, age 6-71 years) with CHM and subjects with normal vision (n = 44; ages 10-50 years) were included. METHODS: Subjects were examined with spectral-domain optical coherence tomography (SD OCT) and near-infrared reflectance imaging...
December 13, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27984356/structural-and-functional-monitoring-of-extramacular-cystoid-spaces-in-a-case-of-x-linked-retinoschisis-treated-with-acetazolamide
#11
Frederick T Collison, Gerald A Fishman
BACKGROUND: Carbonic anhydrase inhibitors (CAIs) have been shown to have a beneficial effect on cystoid macular edema in X-linked retinoschisis (XLRS) and other inherited retinal conditions. The effect of CAIs outside the macula has been less well studied. METHODS: Snellen visual acuity, spectral-domain optical coherence tomography (SD-OCT), kinetic visual field, and dark-adapted single-flash full-field electroretinogram (ERG) testing were all done at baseline and at least one follow-up visit...
December 13, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27977480/comparing-the-performance-of-compass-perimetry-with-humphrey-field-analyzer-in-eyes-with-glaucoma
#12
Harsha L Rao, Sharanya Raveendran, Varsha James, Srilakshmi Dasari, Meena Palakurthy, Hemanth B Reddy, Zia S Pradhan, Dhanaraj A S Rao, Narendra K Puttaiah, Sathi Devi
PURPOSE: To evaluate the reliability indices [fixation losses, false negative response rates (FN) and false positive response rates] and threshold sensitivities obtained from glaucoma patients with a Compass perimeter and to compare the same with the Humphrey field analyzer (HFA). METHODS: In a cross-sectional study, 97 eyes of 58 subjects (64 glaucoma and 33 glaucoma suspect eyes) underwent visual field examination with Compass and HFA. Any test with a fixation losses, FN or FP of >20% was considered unreliable...
December 13, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27956290/objective-evaluation-of-negative-dysphotopsia-with-goldmann-kinetic%C3%A2-perimetry
#13
Natalia Y Makhotkina, Tos T J M Berendschot, Rudy M M A Nuijts
PURPOSE: To compare the extension of peripheral visual fields in phakic and pseudophakic patients and to evaluate whether Goldmann kinetic perimetry can be used as an objective measure of negative dysphotopsia. SETTING: University Eye Clinic, Maastricht University Medical Centre, Maastricht, the Netherlands. DESIGN: Prospective and case-control study. METHODS: Kinetic perimetry was performed with V4e and I4e stimuli...
November 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27935606/structural-and-functional-assessment-of-macula-to-diagnose-glaucoma
#14
H L Rao, R S M Hussain, M Januwada, L N Pillutla, V U Begum, A Chaitanya, S Senthil, C S Garudadri
PurposeTo compare the diagnostic abilities of structural (ganglion cell-inner plexiform layer (GCIPL) thickness measured using spectral domain optical coherence tomography (SDOCT)) and functional (visual sensitivities measured using standard automated perimetry (SAP) and microperimetry (MP)) assessments of macula in glaucoma.MethodsIn a prospective study, 46 control eyes (28 subjects) and 61 glaucoma eyes (46 patients) underwent visual sensitivity estimation at macula (central 10°) by SAP and MP, and GCIPL thickness measurement at macula by SDOCT...
December 9, 2016: Eye
https://www.readbyqxmd.com/read/27928419/bilateral-concurrent-eye-examination-with-a-head-mounted-perimeter-for-diagnosing-functional-visual-loss
#15
Toshiaki Goseki, Hitoshi Ishikawa, Nobuyuki Shoji
The authors here report a case series where bilateral concurrent eye examination, using a head-mounted perimeter (imo®), was employed to facilitate diagnosis of functional visual loss, as regular ophthalmological tests were ineffective. Subjects (11-year-old female, 15-year-old male, and 24-year-old male) were diagnosed with unilateral functional visual loss by using the imo®, at the Kitasato University hospital. The results of the imo® and those of Goldmann perimetry or Humphrey Field Analyzer II differed for all subjects, which is indicative of potential functional visual loss...
December 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27928401/idiopathic-acquired-temporal-wedge-visual-field-defects
#16
Michael J Gilhooley, Clare L Fraser, Sui Wong, Simon J Hickman, Gordon T Plant
Our aim is to report 13 unusual cases of acquired, temporal sectoral scotomas. Such stationary "wedge" field defects have been reported previously in cases of presumed congenital nasal hypoplasia of the optic disc and as a complication of vitreoretinal surgery. To our knowledge, the literature provides no reports of similar defects occurring spontaneously. This is a descriptive clinical case series of 13 patients presenting with sub-acute monocular temporal visual field loss. All were clinically assessed and investigated with Goldmann perimetry, automated Humphrey visual fields, retinal optical coherence tomography, orbital ultrasound, and standard and multi-focal electroretinography...
August 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27906070/subretinal-adipose-tissue-derived-mesenchymal-stem-cell-implantation-in-advanced-stage-retinitis-pigmentosa-a-phase-i-clinical-safety-study
#17
Ayse Oner, Z Burcin Gonen, Neslihan Sinim, Mustafa Cetin, Yusuf Ozkul
BACKGROUND: This prospective clinical case series aimed to investigate the safety of subretinal adipose tissue-derived mesenchymal stem cell (ADMSC) implantation in advanced stage retinitis pigmentosa (RP). METHODS: This study included 11 patients with end-stage RP who received subretinal implantation of ADMSCs. All patients had a total visual field defect and five of them only had light perception. The best corrected visual acuity (BCVA) in the study was 20/2000...
December 1, 2016: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/27896492/hemianopic-line-bisection-error-in-a-patient-with-alzheimer-s-disease
#18
Heeyoung Kang, Soo-Kyoung Kim, Ki-Jong Park, Nack-Cheon Choi, Oh-Young Kwon, Byeong Hoon Lim
Visual symptoms are frequently observed in posterior cortical atrophy compared to typical amnestic Alzheimer's disease (AD). We report the case of a patient with amnestic AD with long-lasting homonymous hemianopia. A 62-year-old woman, who was diagnosed in amnestic AD, complained of visual disturbance. She had left homonymous hemianopia in the perimetry test and left tactile extinction. Regardless of posture, retinotopically leftward error was observed on 21 cm line bisection test. Brain single photon emission computerized tomography (SPECT) showed bilateral temporoparietal hypoperfusion, which was more severe to the right than left side...
November 28, 2016: Neurological Sciences
https://www.readbyqxmd.com/read/27888083/clinical-and-imaging-evaluation-of-the-transuncus-selective-amygdalo-hippocampectomy
#19
Enrico Ghizoni, Roger Matias, Stefan Lieber, Brunno Machado de Campos, Clarissa Lin Yasuda, João Paulo Sant Ana Santos de Souza, Pamela Castro Pereira, Augusto Amato, Andrei Fernandes Joaquim, Tátila Martins Lopes, Helder Tedeschi, Fernando Cendes
BACKGROUND: Various reports described the transuncus approach (TU) as a selective route to the amygdala and hippocampus, but this approach has not yet being submitted to a solid post operative imaging analysis. The objective of this study was to evaluate the anatomy, surgical technique, postoperative imaging analysis and outcome in a series of temporal lobe epilepsy (TLE) patients who underwent to selective amigdalo-hippocampectomy (SHA) via TU. METHODS: This is a prospective study of 25 consecutive patients who underwent to selective amigdalo-hippocampectomy through TU...
November 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27885592/normal-threshold-size-of-stimuli-in-children-using-a-game-based-visual-field-test
#20
Yanfang Wang, Zaria Ali, Siddharth Subramani, Susmito Biswas, Cecilia Fenerty, David B Henson, Tariq Aslam
INTRODUCTION: The aim of this study was to demonstrate and explore the ability of novel game-based perimetry to establish normal visual field thresholds in children. METHODS: One hundred and eighteen children (aged 8.0 ± 2.8 years old) with no history of visual field loss or significant medical history were recruited. Each child had one eye tested using a game-based visual field test 'Caspar's Castle' at four retinal locations 12.7° (N = 118) from fixation...
November 24, 2016: Ophthalmology and Therapy
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