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Perimetry

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https://www.readbyqxmd.com/read/28419563/whole-exome-sequencing-identified-a-novel-single-base-pair-insertion-mutation-in-the-eys-gene-in-a-six-generation-family-with-retinitis-pigmentosa
#1
Jamil Amjad Hashmi, Maan Abdullah Albarry, Ahmed Almatrafi, Alia M Albalawi, Amir Mehmood, Sulman Basit
Retinitis pigmentosa (RP) is a group of inherited progressive retinal dystrophies (RD) and is characterized by photoreceptor degeneration. RP is clinically and genetically heterogeneous disorder. More than 70 genes are known and, thus, identification of causative genes and mutations in known genes is challenging. This study was designed to identify the underlying genetic defect in a large extended Saudi family with multiple RP affected members. Fundus photography, Optical Coherence Tomography (OCT) and visual field perimetry were performed for affected individuals...
April 16, 2017: Congenital Anomalies
https://www.readbyqxmd.com/read/28416494/long-term-clinical-course-of-normotensive-preperimetric-glaucoma
#2
Akira Sawada, Yusuke Manabe, Tetsuya Yamamoto, Chisato Nagata
AIMS: To evaluate the long-term clinical course of normotensive preperimetric glaucoma (PPG). METHODS: We retrospectively analysed 130 eyes of 130 patients initially diagnosed as having preperimetric normal tension glaucoma and followed these cases for at least 5 years with reliable visual field (VF) examinations by standard automated perimetry. When the VF defect (VFD) met Anderson-Patella's criteria on three or more consecutive examinations, and consistently met the criteria on subsequent examinations, we concluded that a glaucomatous VFD was present...
April 17, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28410763/correlation-between-upper-limb-volume-and-arterial-and-venous-blood-flow-velocity-in-lymphedema-secondary-to-breast-cancer-treatment
#3
Monique Silva Rezende, Ana Luiza Marsengo, Amanda Apolinário, Vânia Tie Koga Ferreira, Elaine Caldeira de Oliveira Guirro
OBJECTIVE: The purpose of this study was to correlate upper limb volume and arterial and venous blood flow velocity in breast cancer survivors. METHODS: A cross-sectional study was conducted on 30 women with lymphedema and a mean age of 55.60 years (standard deviation = 8.12). For the assessment of upper limb volume, perimetry was performed with measures at 6 points on the limb, which were mathematically calculated as volume. The blood flow velocity of the axillary and brachial arteries and veins were assessed by Doppler ultrasound with a probe at 4 MHz...
April 12, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28406771/comparison-of-the-long-term-and-short-term-fluctuations-of-frequency-doubling-technology-perimetry-between-peripheral-and-paracentral-zones-of-visual-field
#4
Faisal Aziz Khan, Mazhar Ishaq, Amer Yaqub
OBJECTIVE: To compare the long- and short-term fluctuations of frequency doubling technology perimetry between peripheral and paracentral zone and determine the relationship between threshold sensitivity and long- and short-term fluctuation within peripheral and paracentral zone of visual field. STUDY DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: Eye Department, United Nations, Pakistan Field Hospital Level-3 Darfur, Sudan, from February to July 2015...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28404802/visual-discrimination-training-improves-humphrey-perimetry-in-chronic-cortically-induced-blindness
#5
Matthew R Cavanaugh, Krystel R Huxlin
OBJECTIVE: To assess if visual discrimination training improves performance on visual perimetry tests in chronic stroke patients with visual cortex involvement. METHODS: 24-2 and 10-2 Humphrey visual fields were analyzed for 17 chronic cortically blind stroke patients prior to and following visual discrimination training, as well as in 5 untrained, cortically blind controls. Trained patients practiced direction discrimination, orientation discrimination, or both, at nonoverlapping, blind field locations...
April 12, 2017: Neurology
https://www.readbyqxmd.com/read/28400890/comparison-of-ethnic-specific-databases-in-heidelberg-retina-tomography-3-to-discriminate-between-early-glaucoma-and-normal-chinese-eyes
#6
Xiu Ling Tan, Sae Cheong Yap, Xiang Li, Leonard W Yip
PURPOSE: To compare the diagnostic accuracy of the 3 race-specific normative databases in Heidelberg Retina Tomography (HRT)-3, in differentiating between early glaucomatous and healthy normal Chinese eyes. METHOD: 52 healthy volunteers and 25 glaucoma patients were recruited for this prospective cross-sectional study. All underwent standardized interviews, ophthalmic examination, perimetry and HRT optic disc imaging. Area under the curve (AUC) receiver operating characteristics, sensitivity and specificity were derived to assess the discriminating abilities of the 3 normative databases, for both Moorfields Regression Analysis (MRA) and Glaucoma Probability Score (GPS)...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28394809/structure-function-relationship-between-the-bruch-membrane-opening-based-minimum-rim-width-and-visual-field-defects-in-advanced-glaucoma
#7
Serhat Imamoglu, Nimet Burcu Celik, Mehmet S Sevim, Gokhan Pekel, Nimet Yesim Ercalik, Esra Turkseven Kumral, Handan Bardak
PURPOSE: To investigate the relationship between the Bruch membrane opening-minimum rim width (BMO-MRW) (global and temporal) parameters with spectral-domain optical coherence tomography (SD-OCT) and visual field (VF) sensitivity on the 10-2 test in patients with advanced glaucoma. MATERIALS AND METHODS: This cross-sectional, observational study included a total of 33 eyes of 29 patients. To evaluate VF sensitivity, automated white-on-white perimetry was performed using a Humphrey field analyzer...
April 7, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28388545/the-diagnostic-value-of-white-blood-cell-neutrophil-neutrophil-to-lymphocyte-ratio-and-lymphocyte-to-monocyte-ratio-in-patients-with-primary-angle-closure-glaucoma
#8
Shengjie Li, Wenjun Cao, Jianping Han, Binghua Tang, Xinghuai Sun
OBJECTIVE: Inflammatory mechanisms may have a role in the pathogenesis of primary angle closure glaucoma (PACG). The objective of this study was to investigate the diagnostic value of white blood cell (WBC), neutrophil, neutrophil to lymphocyte ratio (NLR), and lymphocyte to monocyte ratio (LMR) in patients with PACG and its association with glaucoma severity. METHOD: The study was retrospectively assessed in 771 consecutive PACG patients and 770 control subjects, laboratory parameters and clinical parameters were obtained from a medical data platform...
March 25, 2017: Oncotarget
https://www.readbyqxmd.com/read/28384671/acute-zonal-cone-photoreceptor-outer-segment-loss
#9
Tomas S Aleman, Harpal S Sandhu, Leona W Serrano, Anastasia Traband, Marisa K Lau, Grazyna Adamus, Robert A Avery
Importance: The diagnostic path presented narrows down the cause of acute vision loss to the cone photoreceptor outer segment and will refocus the search for the cause of similar currently idiopathic conditions. Objective: To describe the structural and functional associations found in a patient with acute zonal occult photoreceptor loss. Design, Setting, and Participants: A case report of an adolescent boy with acute visual field loss despite a normal fundus examination performed at a university teaching hospital...
April 6, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28368999/evaluation-of-a-novel-visual-field-analyzer-application-for-automated-classification-of-glaucoma-severity
#10
Renato A S Germano, Carlos Gustavo de Moraes, Remo Susanna, Daniel O Dantas, Edson D S Neto
PURPOSE: To describe the Glaucoma Staging Application (GSA), a new application for automated classification of visual field (VF) severity that can be used in any Humphrey perimeters. We also tested and validated its performance in staging glaucomatous VFs defects and assessed its reproducibility. MATERIALS AND METHODS: The GSA is based upon the modified University of São Paulo Glaucoma Visual Field Staging System, and consists of 3 sections: severity based on the visual field index; defect location based on eccentricity; and extent of topographic damage by hemifields...
March 31, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28368051/comparing-multifocal-pupillographic-objective-perimetry-mfpop-and-multifocal-visual-evoked-potentials-mfvep-in-retinal-diseases
#11
Faran Sabeti, Andrew C James, Corinne F Carle, Rohan W Essex, Andrew Bell, Ted Maddess
Multifocal pupillographic objective perimetry (mfPOP) shows regions of slight hypersensitivity away from retinal regions damaged by diabetes or age-related macular degeneration (AMD). This study examines if such results also appear in multifocal visual evoked potentials (mfVEPs) recorded on the same day in the same patients. The pupil control system receives input from the extra-striate cortex, so we also examined evidence for such input. We recruited subjects with early type 2 diabetes (T2D) with no retinopathy, and patients with unilateral exudative AMD...
April 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28355310/tangent-screen-perimetry-in-the-evaluation-of-visual-field-defects-associated-with-ptosis-and-dermatochalasis
#12
Molly L Fuller, César A Briceño, Christine C Nelson, Elizabeth A Bradley
PURPOSE: To determine if tangent visual fields gathered during assessment of superior visual field deficits caused by blepharoptosis and dermatochalasis offer good correlation to clinical exam in a time and cost efficient manner. METHODS: Prospective, observational case series. Subjects included all patients referred to a single surgeon (CCN) who underwent surgical correction of blepharoptosis and/or dermatochalasis. Preoperatively and postoperatively, upper margin-to-reflex distances were assessed...
2017: PloS One
https://www.readbyqxmd.com/read/28348627/visual-field-losses-in-patients-with-migraine-without-aura-and-tension-type-headache
#13
Arif Ü Yener, Osman Korucu
The aim of the study was to compare the visual fields during pain attacks in the patients with migraine without aura and tension-type headache using automated perimetry. In this study 25 patients with migraine and 25 patients with tension-type headache were evaluated.The optic disc, macula and retina were assessed and patients with normal values were enrolled into the study. Intraocular pressure of all patients were measured. Furthermore, visual field test was applied to both groups using Humphrey field analyzer (Carl-Zeiss Meditec, model-745 i, Dublin, CA, USA)...
April 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/28346038/recruitment-and-testing-protocol-in-the-national-eye-health-survey-a-population-based-eye-study-in-australia
#14
Joshua Foreman, Stuart Keel, Peter van Wijngaarden, Hugh R Taylor, Mohamed Dirani
PURPOSE: To present the recruitment and testing methodology of the National Eye Health Survey (NEHS), a population-based study that aimed to determine the prevalence and causes of vision impairment and blindness in Australia. METHODS: Non-Indigenous Australians aged 50 years and older and Indigenous Australians aged 40 years and older were recruited using a door-to-door approach from 30 randomly selected geographical areas, stratified by remoteness. Participants underwent a vision examination, anterior segment assessment, intraocular pressure testing, perimetry, and fundus photography...
March 27, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28333896/relationship-of-optic-nerve-structure-and-function-to-peripapillary-vessel-density-measurements-of-optical-coherence-tomography-angiography-in-glaucoma
#15
Harsha L Rao, Zia S Pradhan, Robert N Weinreb, Srilakshmi Dasari, Mohammed Riyazuddin, Sharanya Raveendran, Narendra K Puttaiah, Jayasree P Venugopal, Dhanaraj A S Rao, Sathi Devi, Kaweh Mansouri, Carroll A B Webers
PURPOSE: To evaluate the sectoral and global structure-structure (vessel density-retinal nerve fiber layer thickness) and structure-function (vessel density-visual sensitivity loss) relationships of peripapillary vessel density measurements on optical coherence tomography angiography in primary open-angle glaucoma and to determine if fractional polynomial (FP) models characterize the relationships better than linear models. MATERIALS AND METHODS: In a cross-sectional study, structure-structure and structure-function relationships of peripapillary vessel densities were determined in 227 eyes of 143 subjects (63 control and 164 primary open-angle glaucoma eyes) who had undergone standard automated perimetry and optical coherence tomography testing within 6 months of each other, using linear and FP models...
March 22, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28333895/visual-field-defects-in-young-patients-with-open-angle-glaucoma-comparison-between-high-tension-and-normal-tension-glaucoma
#16
Ji-Hye Park, Chungkwon Yoo, Jinhwan Park, Yong Yeon Kim
PURPOSE: To investigate the clinical features of young Korean patients with open-angle glaucoma (OAG), and to compare visual field (VF) defects between patients with normal-tension glaucoma (NTG) and those with high-tension glaucoma (HTG). MATERIALS AND METHODS: Patients with OAG younger than 40 years of age were divided into NTG and HTG groups based on untreated intraocular pressure (IOP) level. The patients were matched according to the mean deviation of standard automated perimetry...
March 22, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28333894/m-s-smart-system-contrast-sensitivity-measurements-compared-with-standard-visual-function-measurements-in-primary-open-angle-glaucoma-patients
#17
Jessica L Liu, J Jason McAnany, Jacob T Wilensky, Ahmad A Aref, Thasarat S Vajaranant
PURPOSE: To evaluate the nature and extent of letter contrast sensitivity (CS) deficits in glaucoma patients using a commercially available computer-based system (M&S Smart System II) and to compare the letter CS measurements to standard clinical measures of visual function. METHODS: Ninety-four subjects with primary open-angle glaucoma participated. Each subject underwent visual acuity, letter CS, and standard automated perimetry testing (Humphrey SITA 24-2). All subjects had a best-corrected visual acuity (BCVA) of 0...
March 22, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28332008/case-of-adult-onset-neuronal-intranuclear-hyaline-inclusion-disease-with-negative-electroretinogram
#18
Wataru Yamada, Akira Takekoshi, Kyoko Ishida, Kiyofumi Mochizuki, Jun Sone, Gen Sobue, Yuichi Hayashi, Takashi Inuzuka, Yozo Miyake
PURPOSE: To report the findings in a 72-year-old man with neuronal intranuclear hyaline inclusion disease (NIHID) with the negative-type electroretinogram (ERG) and without night blindness. METHODS: Standard ophthalmological examinations including the medical history, measurements of the best-corrected visual acuity and intraocular pressures, slit-lamp biomicroscopy, ophthalmoscopy, spectral-domain optical coherence tomography, fundus autofluorescence, and perimetry were performed...
March 22, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28299007/correlation-between-visual-field-index-and-other-functional-and-structural-measures-in-glaucoma-patients-and-suspects
#19
Natalia A Iutaka, Rubens A Grochowski, Niro Kasahara
PURPOSE: To evaluate the correlation between visual field index (VFI) and both structural and functional measures of the optic disc in primary open angle glaucoma patients and suspects. METHODS: In this retrospective study, 162 glaucoma patients and suspects underwent standard automated perimetry (SAP), retinography, and retinal nerve fiber layer (RNFL) measurement. The optic disc was stratified according to the vertical cup/disc ratio (C/D) and sorted by the disc damage likelihood scale (DDLS)...
January 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28291960/trabeculectomy-with-ologen-versus-mitomycin-c-in-juvenile-open-angle-glaucoma-a-1-year-study
#20
Fathi El-Sayyad, Heba Magdy Ahmed El-Saied, Mohamad Amr Salah Eddin Abdelhakim
BACKGROUND: We assessed bleb morphology and the intraocular pressure (IOP)-lowering effect of trabeculectomy with ologen compared to mitomycin C (MMC) in juvenile open-angle glaucoma (JOAG). METHODS: This is a prospective interventional comparative study conducted on 40 eyes (20 patients) with medically uncontrolled JOAG, randomly operating one eye for trabeculectomy with ologen (group A: 20 eyes) and the other with MMC (group B: 20 eyes). IOP measurement, SITA standard perimetry, and spectral domain optical coherence tomography (OCT) for retinal nerve fiber layer (RNFL) thickness were all done pre- and postoperatively...
2017: Ophthalmic Research
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