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https://www.readbyqxmd.com/read/28931299/-steroid-induced-glaucoma-as-a-complication-of-atopic-eczema-local-treatment
#1
T Řeháková, A Stepanov, N Jirásková
The authors present case reports of two young women, who visited the outpatient Department of Ophthalmology clinic, University Hospital in Hradec Králové with lacklustre subjective eye complaints lasting over few weeks. It the beginning high values of intraocular pressure in both eyes and severe glaucomatous damage of the optic nerve head were find out, which was confirm using perimetry and OCT (optical coherence tomography). The anamnesis has shown that both patients have been treated for atopic eczema since their childhood...
2017: Ceská a Slovenská Oftalmologie
https://www.readbyqxmd.com/read/28915799/analysis-of-various-factors-affecting-pupil-size-in-patients-with-glaucoma
#2
Ji Woong Park, Bong Hui Kang, Ji Won Kwon, Kyong Jin Cho
BACKGROUND: Pupil size is an important factor in predicting post-operative satisfaction. We assessed the correlation between pupil size, measured by Humphrey static perimetry, and various affecting factors in patients with glaucoma. METHODS: In total, 825 eyes of 415 patients were evaluated retrospectively. Pupil size was measured with Humphrey static perimetry. Comparisons of pupil size according to the presence of glaucoma were evaluated, as were correlations between pupil size and various factors, including age, logMAR best corrected visual acuity (BCVA), retinal nerve fiber layer (RNFL) thickness, spherical equivalent, intraocular pressure, axial length, central corneal thickness, white-to-white, and the kappa angle...
September 16, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28900607/de-novo-intraocular-amyloid-deposition-after-hepatic-transplantation-in-familial-amyloidotic-polyneuropathy
#3
Ivo Filipe Gama, Leonor Duarte Almeida
The familiar amyloid polyneuropathy (FAP) is a rare autosomal-dominant systemic amyloidosis. Amyloid deposition occurs more frequently and extensively in the vitq. The increase in intraocular pressure (IOP) is a result of deposition of transthyretin (TTR) in trabecular meshwork. Rarely, the amyloid deposition in anterior segment can be more exuberant than in posterior segment. A 42 years old man, with FAP (Val30Met mutation), liver transplantation in 1997. He was asymptomatic, without any significant ocular abnormality until 2011...
August 24, 2017: World Journal of Transplantation
https://www.readbyqxmd.com/read/28900577/comparison-of-threshold-saccadic-vector-optokinetic-perimetry-svop-and-standard-automated-perimetry-sap-in-glaucoma-part-ii-patterns-of-visual-field-loss-and-acceptability
#4
Alice D McTrusty, Lorraine A Cameron, Antonios Perperidis, Harry M Brash, Andrew J Tatham, Pankaj K Agarwal, Ian C Murray, Brian W Fleck, Robert A Minns
PURPOSE: We compared patterns of visual field loss detected by standard automated perimetry (SAP) to saccadic vector optokinetic perimetry (SVOP) and examined patient perceptions of each test. METHODS: A cross-sectional study was done of 58 healthy subjects and 103 with glaucoma who were tested using SAP and two versions of SVOP (v1 and v2). Visual fields from both devices were categorized by masked graders as: 0, normal; 1, paracentral defect; 2, nasal step; 3, arcuate defect; 4, altitudinal; 5, biarcuate; and 6, end-stage field loss...
September 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28900576/comparison-of-saccadic-vector-optokinetic-perimetry-and-standard-automated-perimetry-in-glaucoma-part-i-threshold-values-and-repeatability
#5
Ian C Murray, Antonios Perperidis, Lorraine A Cameron, Alice D McTrusty, Harry M Brash, Andrew J Tatham, Pankaj K Agarwal, Brian W Fleck, Robert A Minns
PURPOSE: We evaluated threshold saccadic vector optokinetic perimetry (SVOP) and compared results to standard automated perimetry (SAP). METHODS: A cross-sectional study was done including 162 subjects (103 with glaucoma and 59 healthy subjects) recruited at a university hospital. All subjects underwent SAP and threshold SVOP. SVOP uses an eye tracker to monitor eye movement responses to stimuli and determines if stimuli have been perceived based on the vector of the gaze response...
September 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28882754/mini-review-far-peripheral-vision
#6
Michael J Simpson
The region of far peripheral vision, beyond 60 degrees of visual angle, is important to the evaluation of peripheral dark shadows (negative dysphotopsia) seen by some intraocular lens (IOL) patients. Theoretical calculations show that the limited diameter of an IOL affects ray paths at large angles, leading to a dimming of the main image for small pupils, and to peripheral illumination by light bypassing the IOL for larger pupils. These effects are rarely bothersome, and cataract surgery is highly successful, but there is a need to improve the characterization of far peripheral vision, for both pseudophakic and phakic eyes...
September 9, 2017: Vision Research
https://www.readbyqxmd.com/read/28868033/sturge-weber-syndrome-associated-with-monolateral-ocular-melanocytosis-iris-mammillations-and-diffuse-choroidal-haemangioma
#7
Andrea Maria Plateroti, Rocco Plateroti, Roberto Mollo, Aloisa Librando, Maria Teresa Contestabile, Vito Fenicia
We present the case of a 12-year-old boy with Sturge-Weber syndrome and ocular melanocytosis who presented with bilateral naevus flammeus of the face and hyperpigmentation of the right iris associated with ipsilateral iris mammillations. The patient had glaucoma and a diffuse choroidal haemangioma of the right eye. Optical coherence tomography of the anterior segment confirmed iris hyper-pigmentation and did not show abnormalities of the chamber angle structures. B-scan ultrasonography and enhanced depth imaging optical coherence tomography were performed and showed a marked difference in thickness and reflectance between the right and left choroid...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28865878/will-perimetry-be-performed-to-monitor-glaucoma-in-2025
#8
Andrew S Camp, Robert N Weinreb
Visual field testing has played an essential role in the diagnosis and management of glaucoma for more than a century. Methods to examine the visual field have been refined from early kinetic perimetry to current standard automated perimetry (SAP). Clinicians now use SAP for the diagnosis and management of glaucoma throughout the world. Various testing paradigms and analytic methods have been developed to simplify the diagnosis of glaucoma and the interpretation of progression. Moreover, strategies have been implemented to improve patient experience with visual field testing and to increase reliability...
August 30, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28863943/the-effect-of-testing-reliability-on-visual-field-sensitivity-in-normal-eyes-the-singapore-chinese-eye-study
#9
Nicholas Y Q Tan, Yih-Chung Tham, Victor Koh, Duc Quang Nguyen, Carol Y Cheung, Tin Aung, Tien Yin Wong, Ching-Yu Cheng
PURPOSE: To quantitatively determine how the reliability indices in standard automated perimetry (SAP) affect the global indices of visual field (VF) results in nonglaucomatous eyes. DESIGN: Observational, cross-sectional study. PARTICIPANTS: A total of 830 adults aged 40 to 80 years, without visual impairment, glaucoma, significant cataract, and major eye diseases, were selected from the population-based Singapore Chinese Eye Study (SCES)...
August 29, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28863407/high-symmetry-of-visual-acuity-and-visual-fields-in-rpgr-linked-retinitis-pigmentosa
#10
Julia-Sophia Bellingrath, G Alex Ochakovski, Immanuel P Seitz, Susanne Kohl, Eberhart Zrenner, Nicola Hanig, Holger Prokisch, Bernhard H Weber, Susan M Downes, Simon Ramsden, Robert E MacLaren, M Dominik Fischer
Purpose: Mutations in retinitis pigmentosa GTPase regulator (RPGR) cause 70% to 90% of X-linked retinitis pigmentosa (XLRP3) cases, making this gene a high-yield target for gene therapy. This study analyzed the utility of relevant clinical biomarkers to assess symmetry and rate of progression in XLRP3. Methods: A retrospective, cross-sectional analysis of 50 XLRP3 patients extracted clinical data including visual acuity (VA), visual fields (I4e and III4e targets), foveal thickness, and ERG data points alongside molecular genetic data...
September 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28863215/multifocal-visual-evoked-potential-in-eyes-with-temporal-hemianopia-from-chiasmal-compression-correlation-with-standard-automated-perimetry-and-oct-findings
#11
Rafael M Sousa, Maria K Oyamada, Leonardo P Cunha, Mário L R Monteiro
Purpose: To verify whether multifocal visual evoked potential (mfVEP) can differentiate eyes with temporal hemianopia due to chiasmal compression from healthy controls. To assess the relationship between mfVEP, standard automated perimetry (SAP), and Fourier domain-optical coherence tomography (FD-OCT) macular and peripapillary retinal nerve fiber layer (RNFL) thickness measurements. Methods: Twenty-seven eyes with permanent temporal visual field (VF) defects from chiasmal compression on SAP and 43 eyes of healthy controls were submitted to mfVEP and FD-OCT scanning...
September 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28861036/contralesional-trunk-rotation-dissociates-real-vs-pseudo-visual-field-defects-due-to-visual-neglect-in-stroke-patients
#12
Thomas Nyffeler, Rebecca E Paladini, Simone Hopfner, Oliver Job, Tobias Nef, Tobias Pflugshaupt, Tim Vanbellingen, Stephan Bohlhalter, René M Müri, Georg Kerkhoff, Dario Cazzoli
In stroke patients, the clinical presentation of visual field defects (VFDs) is frequently accompanied by visual neglect, i.e., the inability to attend and respond to the contralesional space. However, the diagnostic discrimination between the lack of reactions to contralesional stimuli due to VFDs or visual neglect is challenging during clinical examination. This discrimination is particularly relevant, since both clinical pictures are associated with different therapeutic approaches and outcomes. The aim of this study was to systematically investigate the effectiveness of trunk rotation toward the contralesional side-a manipulation dissociating the coordinate system of the trunk from that of the head and eyes-in disentangling real VFDs from "pseudo-VFDs" that occur due to visual neglect...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28860969/long-lasting-enhancement-of-visual-perception-with-repetitive-noninvasive-transcranial-direct-current-stimulation
#13
Janina R Behrens, Antje Kraft, Kerstin Irlbacher, Holger Gerhardt, Manuel C Olma, Stephan A Brandt
Understanding processes performed by an intact visual cortex as the basis for developing methods that enhance or restore visual perception is of great interest to both researchers and medical practitioners. Here, we explore whether contrast sensitivity, a main function of the primary visual cortex (V1), can be improved in healthy subjects by repetitive, noninvasive anodal transcranial direct current stimulation (tDCS). Contrast perception was measured via threshold perimetry directly before and after intervention (tDCS or sham stimulation) on each day over 5 consecutive days (24 subjects, double-blind study)...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28858160/evaluating-the-quality-of-life-of-glaucoma-patients-using-the-state-trait-anxiety-inventory
#14
Yasumasa Otori, Genichiro Takahashi, Mitsuyoshi Urashima, Yasuaki Kuwayama
PURPOSE: To evaluate anxiety felt by glaucoma patients. PATIENTS AND METHODS: Four-hundred and seventy-two glaucoma patients responded to a questionnaire on anxiety, subjective symptoms, and vision-related quality of life (VR-QOL) associated with glaucoma. Anxiety was evaluated using the State-Trait Anxiety Inventory (STAI), state anxiety (STAI-State) subscale along with our novel questionnaire, assessing visual function and subjective symptoms, specialized for glaucoma...
August 28, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28855198/diagnostic-accuracy-of-optical-coherence-tomography-for-diagnosing-glaucoma-secondary-analyses-of-the-gate-study
#15
Gianni Virgili, Manuele Michelessi, Jonathan Cook, Charles Boachie, Jennifer Burr, Katie Banister, David F Garway-Heath, Rupert R A Bourne, Almudena Asorey Garcia, Craig R Ramsay, Augusto Azuara-Blanco
BACKGROUND/AIMS: To assess the diagnostic performance of retinal nerve fibre layer (RNFL) data of optical coherence tomography (OCT) for detecting glaucoma. METHODS: Secondary analyses of a prospective, multicentre diagnostic study (Glaucoma Automated Tests Evaluation (GATE)) referred to hospital eye services in the UK were conducted. We included data from 899 of 966 participants referred to hospital eye services with suspected glaucoma or ocular hypertension. We used both eyes' data and logistic regression-based receiver operator characteristics analysis to build a set of models to measure the sensitivity and specificity of the average and inferior quadrant RNFL thickness data of OCT...
August 30, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28844641/performance-of-an-ipad-application-to-detect-moderate-and-advanced-visual-field-loss-in-nepal
#16
Chris A Johnson, Suman Thapa, Yu Xiang George Kong, Alan L Robin
PURPOSE: To evaluate the accuracy and efficiency of Visual Fields Easy (VFE), a free iPad app, for performing suprathreshold perimetric screening. DESIGN: Prospective, cross-sectional validation study. METHODS: We performed screening visual fields using a calibrated iPad 2 with the VFE application on 206 subjects (411 eyes): 210 normal (NL), 183 glaucoma (GL), and 18 diabetic retinopathy (DR) at Tilganga Institute of Ophthalmology, Kathmandu, Nepal...
August 25, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28836391/glaucoma-progression-detection-with-frequency-doubling-technology-fdt-compared-to-standard-automated-perimetry-sap-in-the-groningen-longitudinal-glaucoma-study
#17
Christiaan Wesselink, Nomdo M Jansonius
PURPOSE: To determine the usefulness of frequency doubling perimetry (FDT) for progression detection in glaucoma, compared to standard automated perimetry (SAP). METHODS: Data were used from 150 eyes of 150 glaucoma patients from the Groningen Longitudinal Glaucoma Study. After baseline, SAP was performed approximately yearly; FDT every other year. First and last visit had to contain both tests. Using linear regression, progression velocities were calculated for SAP (Humphrey Field Analyzer) mean deviation (MD) and FDT MD and the number of test locations with a total deviation probability below p < 0...
September 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28829843/magnetic-resonance-imaging-of-optic-nerve-traction-during-adduction-in-primary-open-angle-glaucoma-with-normal-intraocular-pressure
#18
Joseph L Demer, Robert A Clark, Soh Youn Suh, JoAnn A Giaconi, Kouros Nouri-Mahdavi, Simon K Law, Laura Bonelli, Anne L Coleman, Joseph Caprioli
Purpose: We used magnetic resonance imaging (MRI) to ascertain effects of optic nerve (ON) traction in adduction, a phenomenon proposed as neuropathic in primary open-angle glaucoma (POAG). Methods: Seventeen patients with POAG and maximal IOP ≤ 20 mm Hg, and 31 controls underwent MRI in central gaze and 20° to 30° abduction and adduction. Optic nerve and sheath area centroids permitted computation of midorbital lengths versus minimum paths. Results: Average mean deviation (±SEM) was -8...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28812936/investigation-of-goldmann-perimetry-in-evaluation-of-patients-for-upper-eyelid-blepharoplasty
#19
John D Pemberton, Michael Salter, Aaron Fay, Bradley Thuro, Horace Spencer, Omar Dajani
PURPOSE: To determine if preoperative Goldmann Visual Field (GVF) testing in patients with functional dermatochalasis accurately depicts the postoperative superior visual field (SVF) outcome. METHODS: A prospective cohort study was done to compare preoperative and postoperative GVF field tests in patients undergoing upper eyelid blepharoplasty for treatment of dermatochalasis. This study was conducted in accordance with the Declaration of Helsinki and approved by the University of Arkansas for Medical Sciences institutional review board...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28811934/the-estimates-of-retinal-ganglion-cell-counts-performed-better-than-isolated-structure-and-functional-tests-for-glaucoma-diagnosis
#20
Bruno L B Esporcatte, Andrea C Kara-José, Luiz Alberto S Melo, Luciano M Pinto, Ivan M Tavares
PURPOSE: To evaluate the diagnostic accuracy of retinal ganglion cell (RGC) counts as estimated by combining data from standard automated perimetry (SAP) and spectral domain optical coherence tomography (SD-OCT). METHODS: Healthy individuals and glaucoma patients were included in this cross-sectional study. All eyes underwent 24-2 SITA SAP and structural imaging tests. RGC count estimates were obtained using a previously described algorithm, which combines estimates of RGC numbers from SAP sensitivity thresholds and SD-OCT retinal nerve fiber layer (RNFL) average thickness...
2017: Journal of Ophthalmology
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