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https://www.readbyqxmd.com/read/29240614/a-measure-of-the-potential-impact-of-hospital-community-health-activities-on-population-health-and-equity
#1
James W Begun, Linda M Kahn, Brooke A Cunningham, Jan K Malcolm, Sandra Potthoff
CONTEXT: Many hospitals in the United States are exploring greater investment in community health activities that address upstream causes of poor health. OBJECTIVE: Develop and apply a measure to categorize and estimate the potential impact of hospitals' community health activities on population health and equity. DESIGN, SETTING, AND PARTICIPANTS: We propose a scale of potential impact on population health and equity, based on the cliff analogy developed by Jones and colleagues...
December 13, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29239954/analysis-of-inpatient-falls-after-total-knee-arthroplasty-in-patients-with-continuous-femoral-nerve-block
#2
Lloyd R Turbitt, Paul G McHardy, Michel Casanova, Joel Shapiro, Lisa Li, Stephen Choi
Continuous femoral nerve block (cFNB) is thought to increase the risk of falls after total knee arthroplasty (TKA). Previous studies have failed to consider the timing of cFNB removal in relation to inpatient falls. We investigated all inpatient falls after TKA over a 3-year period using our institutional safety report database. Ninety-five falls were reported from a total of 3745 patients. The frequency of falls after TKA persisted at a similar rate despite removal of cFNB and likely regression of femoral nerve block...
December 11, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29239746/stepping-reaction-time-and-gait-adaptability-are-significantly-impaired-in-people-with-parkinson-s-disease-implications-for-fall-risk
#3
Maria Joana D Caetano, Stephen R Lord, Natalie E Allen, Matthew A Brodie, Jooeun Song, Serene S Paul, Colleen G Canning, Jasmine C Menant
BACKGROUND: Decline in the ability to take effective steps and to adapt gait, particularly under challenging conditions, may be important reasons why people with Parkinson's disease (PD) have an increased risk of falling. This study aimed to determine the extent of stepping and gait adaptability impairments in PD individuals as well as their associations with PD symptoms, cognitive function and previous falls. METHODS: Thirty-three older people with PD and 33 controls were assessed in choice stepping reaction time, Stroop stepping and gait adaptability tests; measurements identified as fall risk factors in older adults...
November 22, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29239565/spatio-temporal-analysis-and-visualisation-of-the-anthrax-epidemic-situation-in-livestock-in-kazakhstan-over-the-period-1933-2016
#4
Sarsenbay K Abdrakhmanov, Yersyn Y Mukhanbetkaliyev, Fedor I Korennoy, Bolat Sh Karatayev, Aizada A Mukhanbetkaliyeva, Aruzhan S Abdrakhmanova
An analysis of the anthrax epidemic situation among livestock animals in the Republic of Kazakhstan over the period 1933-2016 is presented. During this time, 4,064 anthrax outbreaks (mainly in cattle, small ruminants, pigs and horses) were recorded. They fall into five historical periods of increase and decrease in the annual anthrax incidence (1933-1953; 1954-1968; 1969-1983; 1984- 2001; and 2002-2016), which has been associated with changes in economic activity and veterinary surveillance. To evaluate the temporal trends of incidence variation for each of these time periods, the following methods were applied: i) spatio-temporal analysis using a space-time cube to assess the presence of hotspots (i...
November 13, 2017: Geospatial Health
https://www.readbyqxmd.com/read/29239000/minimal-physiologically-based-pharmacokinetic-and-drug-drug-disease-interaction-model-of-rivaroxaban-and-verapamil-in-healthy-and-renally-impaired-subjects
#5
Mohamed Ismail, Vincent H Lee, Christina R Chow, Christopher M Rubino
Current dosing recommendations for rivaroxaban advocate dosage reduction in patients with moderate to severe renal impairment and avoidance of concomitant strong inhibitors of CYP3A or P-glycoprotein. However, rivaroxaban dosing in patients with mild renal impairment taking concomitant moderate inhibitors of CYP3A and P-glycoprotein is not addressed. To quantify the impacts of concomitant verapamil administration and renal impairment on rivaroxaban pharmacokinetics, a minimal physiologically based pharmacokinetic model system was developed and used to evaluate potential increases in rivaroxaban exposure and the consequent increase in risk of major bleeding...
December 14, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29238237/adolescent-pre-exposure-prophylaxis-for-hiv-prevention-current-perspectives
#6
REVIEW
Daisy Maria Machado, Alexandre Machado de Sant'Anna Carvalho, Rachel Riera
Adolescents are a critical population that is disproportionately impacted by the HIV epidemic. More than 2 million adolescents between the age group of 10 and 19 years are living with HIV, and millions are at risk of infection. HIV risks are considerably higher among girls, especially in high-prevalence settings such as eastern and southern Africa. In addition to girls, there are other vulnerable adolescent subgroups, such as teenagers, who use intravenous (IV) drugs, gay and bisexual boys, transgender youth, male sex workers, and people who fall into more than one of these categories...
2017: Adolescent Health, Medicine and Therapeutics
https://www.readbyqxmd.com/read/29238177/the-mediating-role-of-psychological-symptoms-on-falls-risk-among-older-adults-with-osteoarthritis
#7
Sumaiyah Mat, Chin Teck Ng, Farhana Fadzil, Faizatul Izza Rozalli, Maw Pin Tan
The purpose of this study was to investigate the role of fear of falling (FoF) and psychological symptoms in explaining the relationship between osteoarthritis (OA) symptom severity and falls. Individuals aged ≥65 years with ≥2 falls or ≥1 injurious fall over the past 12 months were included in the falls group, while volunteers aged ≥65 years with no history of falls over 12 months were recruited as controls. The presence of lower extremity OA was determined radiologically and clinically. Severity of symptoms was assessed using the Western Ontario and McMaster Universities Arthritis Index (WOMAC) questionnaire...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29238175/timed-up-and-go-test-can-predict-recurrent-falls-a-longitudinal-study-of-the-community-dwelling-elderly-in-china
#8
Li Kang, Peipei Han, Jiazhong Wang, Yixuan Ma, Liye Jia, Liyuan Fu, Hairui Yu, Xiaoyu Chen, Kaijun Niu, Qi Guo
Purpose: Falling is a major health problem in community-dwelling elderly individuals. The aim of the present study was to conduct a prospective investigation to evaluate the accuracy of the Timed Up and Go Test (TUGT), 4-meter walking test, and grip strength test to screen for the risk of falls and to determine a cutoff point to be used clinically. Patients and methods: This was a prospective study that included 541 participants. The fall data were obtained via face-to-face interview, and the date, site, and circumstances of any falls were recorded...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29238106/measures-and-effects-on-prevention-of-fall-the-role-of-a-fall-working-group-at-a-university-hospital
#9
Kazuyoshi Kobayashi, Kei Ando, Yuko Inagaki, Yusuke Suzuki, Yoshimasa Nagao, Naoki Ishiguro, Shiro Imagama
Fall in hospitalized patients can cause trauma and fractures, which can reduce ADL and QOL, whereas prevention of fall decreases medical expenses. The purpose of this study is to examine prevention of fall due to intervention from a fall working group established in our hospital. The working group focused on three main points. First, colored wrist bands for patients classified as grade 3 risk for fall are used to alert medical staff. Second, information on fall prevention was distributed to patients. Third, standardization of two bed fences and reduced use of slippers for inpatients have been introduced...
November 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/29236841/the-utility-of-the-records-medical-factors-associated-with-the-medication-errors-in-chronic-disease
#10
Hellen Lilliane da Cruz, Flávia Karla da Cruz Mota, Lorena Ulhôa Araújo, Emerson Cotta Bodevan, Sérgio Ricardo Stuckert Seixas, Delba Fonseca Santos
OBJECTIVE: This study describes the development of the medication history of the medical records to measure factors associated with medication errors among chronic diseases patients in Diamantina, Minas Gerais. METHODS: retrospective, descriptive observational study of secondary data, through the review of medical records of hypertensive and diabetic patients, from March to October 2016. RESULTS: The patients the mean age of patient was 62...
December 11, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/29236379/alcohol-consumption-and-low-risk-drinking-guidelines-among-adults-a-cross-sectional-analysis-from-alberta-s-tomorrow-project
#11
Darren R Brenner, Tiffany R Haig, Abbey E Poirier, Alianu Akawung, Christine M Friedenreich, Paula J Robson
INTRODUCTION: Moderate to heavy alcohol consumption is a risk factor for all-cause mortality and cancer incidence. Although cross-sectional data are available through national surveys, data on alcohol consumption in Alberta from a large prospective cohort were not previously available. The goal of these analyses was to characterize the levels of alcohol consumption among adults from the Alberta's Tomorrow Project in the context of cancer prevention guidelines. Furthermore, we conducted analyses to examine the relationships between alcohol consumption and other high-risk or risk-related behaviours...
December 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/29235898/flash-glucose-measurements-in-children-with-type-1-diabetes-in-real-life-settings-to-trust-or-not-to-trust
#12
Agnieszka Szadkowska, Andrzej Gawrecki, Arkadiusz Michalak, Dorota Zozulińska-Ziółkiewicz, Wojciech Fendler, Wojciech Młynarski
BACKGROUND AND AIMS: To evaluate the clinical accuracy of a flash glucose monitoring device FreeStyle Libre (FSL) among children with type 1 diabetes in real-world settings during a summer camp. MATERIALS AND METHODS: During a summer camp, children with type 1 diabetes (n = 79, aged 8-18 years) were provided with FSLs for 12 days. On days 3, 7, and 11 of the study, they underwent supervised glucose testing at 8 timepoints. Glycemia was estimated by using FSL and measured with a personal glucometer within a period of 2 min...
December 13, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29235099/variations-from-morning-to-afternoon-of-middle-cerebral-and-umbilical-artery-blood-flow-and-fetal-heart-rate-variability-and-fetal-characteristics-in-the-normally-developing-fetus
#13
Tehila Avitan, Ari Sanders, Ursula Brain, Dan Rurak, Tim F Oberlander, Ken Lim
OBJECTIVE: To determine if there are changes in maternal uterine blood flow, fetal brain blood flow, fetal heart rate variability, and umbilical blood flow between morning (AM) and afternoon (PM) in healthy, uncomplicated pregnancies. STUDY DESIGN: In this prospective study, 68 uncomplicated singleton pregnancies (mean 35 + 0.7 weeks gestation) underwent a standard observational protocol at both 08:00 (AM) and 13:30 (PM) of the same day. This protocol included Doppler measurements of uterine, umbilical, and fetal middle cerebral artery (MCA) volume flow parameters (flow, HR, peak systolic velocity [PSV], PI, and RI) followed by computerized cardiotocography...
December 13, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29234301/balance-screening-of-vestibular-function-in-subjects-aged-4-years-and-older-a-living-laboratory-experience
#14
María Carolina Bermúdez Rey, Torin K Clark, Daniel M Merfeld
To better understand the various individual factors that contribute to balance and the relation to fall risk, we performed the modified Romberg Test of Standing Balance on Firm and Compliant Support, with 1,174 participants between 4 and 83 years of age. This research was conducted in the Living Laboratory® at the Museum of Science, Boston. We specifically focus on balance test condition 4, in which individuals stand on memory foam with eyes closed, and must rely on their vestibular system; therefore, performance in this balance test condition provides a proxy for vestibular function...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29234214/clinical-practice-updates-in-the-management-of-immune-thrombocytopenia
#15
Ayesha M Khan, Halina Mydra, Ana Nevarez
Immune thrombocytopenia (ITP), previously called idiopathic thrombocytopenia purpura, is an autoimmune disorder characterized by a severe reduction in peripheral blood platelet count. In healthy individuals, normal platelet count ranges from 150-450 × 109/L, while in thrombocytopenia counts fall to less than 100 × 109/L.1 In adults, the incidence of ITP is approximately two to four per 100,000.2,3 Bleeding risks, specifically hemorrhage and intracranial hemorrhage, represent the most serious complications for patients with ITP...
December 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29233770/dissipation-kinetics-pre-harvest-residue-limits-and-dietary-risk-assessment-of-the-systemic-fungicide-metalaxyl-in-swiss-chard-grown-under-greenhouse-conditions
#16
Md Humayun Kabir, A M Abd El-Aty, Md Musfiqur Rahman, Hyung Suk Chung, Han Sol Lee, Ji Hoon Jeong, Jing Wang, SungShik Shin, Ho-Chul Shin, Jae-Han Shim
The residual behavior of the systemic fungicide, metalaxyl, in Swiss chard cultivated at two different locations under greenhouse conditions was investigated using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC-UVD). Samples were randomly collected over 14 days and extracted using acetonitrile, partitioned using solid sodium chloride, and a solid-phase extraction (SPE) NH2 cartridge was used for cleanup. The linearity over a concentration range 0.05-50 mg/L was excellent with a coefficient of determination (R2) of 0...
December 9, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29233412/forecasting-academic-success-through-implementation-of-an-online-prerequisite-review-tutorials-program-for-first-year-pharmacy-students
#17
Brendan D Stamper, Amber V Buhler, John P Harrelson, Sigrid C Roberts, Ashim Malhotra, Fawzy A Elbarbry, Deepa Rao, Reza Karimi, R Brigg Turner, Catherine Marlow, Leslie L Devaud
OBJECTIVE: Online prerequisite review (OPR) tutorials were designed and implemented to reinforce foundational scientific material in order to protect in-class time, foster self-directed learning, and ensure all students have similar baseline knowledge. METHODS: Twenty-one tutorials covering undergraduate prerequisite material were developed by faculty and organized into six core modules, comprising basic biology, chemistry, and physiology topics. A quiz on this material was given on the first day of each course...
March 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29233376/a-pharmacy-student-s-role-as-a-teaching-assistant-in-an-undergraduate-medicinal-chemistry-course-implementation-evaluation-and-unexpected-opportunities-for-educational-outreach
#18
Matthew J DellaVecchia, Alyssa M Claudio, Jamie L Fairclough
BACKGROUND AND PURPOSE: To describe 1) a pharmacy student's teaching assistant (TA) role in an undergraduate medicinal chemistry course, 2) an active learning module co-developed by the TA and instructor, and 3) the unexpected opportunities for pharmacy educational outreach that resulted from this collaboration. EDUCATIONAL ACTIVITY AND SETTING: Medicinal Chemistry (CHM3413) is an undergraduate course offered each fall at Palm Beach Atlantic University (PBA). As a TA for CHM3413, a pharmacy student from the Gregory School of Pharmacy (GSOP) at PBA co-developed and implemented an active learning module emphasizing foundational medicinal chemistry concepts as they pertain to performance enhancing drugs (PEDs)...
November 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29232671/predicting-trajectories-of-functional-decline-in-60-to-70-year-old-people
#19
Nini H Jonkman, Vieri Del Panta, Trynke Hoekstra, Marco Colpo, Natasja M van Schoor, Stefania Bandinelli, Luca Cattelani, Jorunn L Helbostad, Beatrix Vereijken, Mirjam Pijnappels, Andrea B Maier
BACKGROUND: Early identification of people at risk of functional decline is essential for delivering targeted preventive interventions. OBJECTIVE: The aim of this study is to identify and predict trajectories of functional decline over 9 years in males and females aged 60-70 years. METHODS: We included 403 community-dwelling participants from the InCHIANTI study and 395 from the LASA study aged 60-70 years at baseline, of whom the majority reported no functional decline at baseline (median 0, interquartile range 0-1)...
December 13, 2017: Gerontology
https://www.readbyqxmd.com/read/29231272/impact-of-fear-of-falling-and-fall-history-on-disability-incidence-among-older-adults-prospective-cohort-study
#20
Keitaro Makino, Hyuma Makizako, Takehiko Doi, Kota Tsutsumimoto, Ryo Hotta, Sho Nakakubo, Takao Suzuki, Hiroyuki Shimada
OBJECTIVE: Fear of falling (FOF) is a major health problem for older adults, present not just in fallers, but also nonfallers. This study examined the impact of FOF and fall history on disability incidence among community-dwelling older adults from a prospective cohort study. METHODS: A total of 5104 older adults living in community settings participated in baseline assessment and were followed up for about 4 years (median 52 mo, range 49-55 mo). At baseline, participants were assessed the presence of FOF and their fall history, and divided into 4 groups: Fall (-) FOF (-), Fall (+) FOF (-), Fall (-) FOF (+), and Fall (+) FOF (+)...
December 12, 2017: International Journal of Geriatric Psychiatry
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