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https://www.readbyqxmd.com/read/28719817/aged-refuse-enhances-anaerobic-digestion-of-waste-activated-sludge
#1
Jianwei Zhao, Lin Gui, Qilin Wang, Yiwen Liu, Dongbo Wang, Bing-Jie Ni, Xiaoming Li, Rui Xu, Guangming Zeng, Qi Yang
In this work, a low-cost alternative approach (i.e., adding aged refuse (AR) into waste activated sludge) to significantly enhance anaerobic digestion of sludge was reported. Experimental results showed that with the addition dosage of AR increasing from 0 to 400 mg/g dry sludge soluble chemical oxygen demand (COD) increased from 1150 to 5240 mg/L at the digestion time of 5 d, while the maximal production of volatile fatty acids (VFA) increased from 82.6 to 183.9 mg COD/g volatile suspended solids. Although further increase of AR addition decreased the concentrations of both soluble COD and VFA, their contents in these systems with AR addition at any concentration investigated were still higher than those in the blank, which resulted in higher methane yields in these systems...
July 14, 2017: Water Research
https://www.readbyqxmd.com/read/28719647/morbidity-outcomes-and-cost-benefit-analysis-of-wildlife-rehabilitation-in-catalonia-spain
#2
Rafael Angel Molina-López, Santi Mañosa, Alex Torres-Riera, Manel Pomarol, Laila Darwich
BACKGROUND: There are few studies of careful examination of wildlife casualties in Wildlife Rehabilitation Centers. These studies are essential for detecting menaces to wild species and providing objective criteria about cost-benefit of treatments in those centers. The release rate is considered the main outcome indicator, but other parameters such as length of stay at the center and a cost-benefit index expressed as number of released animals per euro and day, could be used as reliable estimators of the rehabilitation costs...
2017: PloS One
https://www.readbyqxmd.com/read/28719222/how-drug-life-cycle-management-patent-strategies-may-impact-formulary-management
#3
Jan Berger, Jeffrey D Dunn, Margaret M Johnson, Kurt R Karst, W Chad Shear
Drug manufacturers may employ various life-cycle management patent strategies, which may impact managed care decision making regarding formulary planning and management strategies when single-source, branded oral pharmaceutical products move to generic status. Passage of the Hatch-Waxman Act enabled more rapid access to generic medications through the abbreviated new drug application process. Patent expirations of small-molecule medications and approvals of generic versions have led to substantial cost savings for health plans, government programs, insurers, pharmacy benefits managers, and their customers...
October 2016: American Journal of Managed Care
https://www.readbyqxmd.com/read/28719221/biosimilars-biologics-that-meet-patients-needs-and-healthcare-economics
#4
Mark McCamish, William Yoon, James McKay
Biologics have revolutionized medical care, yet uniform access to these effective medicines remains difficult due to the increasing costs of healthcare. As patent exclusivity on the early biologics wanes, regulatory and legal systems are adapting to bring competition to the field in the form of biosimilars. Biosimilars are biologics that offer the same clinical benefit in one or more of the same indications as the reference biologic drug and bring competition to the biologics space. Legislation creating a pathway resulting in the first US approvals of biosimilars has been in place since 2010, but the regulatory methodology and science of evaluating the sameness of two biologics has been in use for decades...
September 2016: American Journal of Managed Care
https://www.readbyqxmd.com/read/28719138/chevrel-phase-mo6-t8-t-s-se-as-electrodes-for-advanced-energy-storage
#5
REVIEW
Lin Mei, Jiantie Xu, Zengxi Wei, Huakun Liu, Yutao Li, Jianmin Ma, Shixue Dou
With the large-scale applications of electric vehicles in recent years, future batteries are required to be higher in power and possess higher energy densities, be more environmental friendly, and have longer cycling life, lower cost, and greater safety than current batteries. Therefore, to develop alternative electrode materials for advanced batteries is an important research direction. Recently, the Chevrel phase Mo6 T8 (T = S, Se) has attracted increasing attention as electrode candidate for advanced batteries, including monovalent (e...
July 18, 2017: Small
https://www.readbyqxmd.com/read/28718325/collaborative-care-for-psychiatric-disorders-in-older-adults-a-systematic-review
#6
Pallavi Dham, Sarah Colman, Karen Saperson, Carrie McAiney, Lillian Lourenco, Nick Kates, Tarek K Rajji
OBJECTIVE: To evaluate the mode of implementation, clinical outcomes, cost-effectiveness, and the factors influencing uptake and sustainability of collaborative care for psychiatric disorders in older adults. DESIGN: Systematic review. SETTING: Primary care, home health care, seniors' residence, medical inpatient and outpatient. PARTICIPANTS: Studies with a mean sample age of 60 years and older. INTERVENTION: Collaborative care for psychiatric disorders...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28717748/bevacizumab-in-advanced-cervical-cancer-issues-and-challenges-for-low-and-middle-income-countries
#7
Bishal Gyawali, Mahesh Iddawela
Bevacizumab became the first molecular antibody to show survival benefit in advanced cervical cancer. In the GOG-0240 (Paclitaxel and Cisplatin or Topotecan With or Without Bevacizumab in Treating Patients With Stage IVB, Recurrent, or Persistent Cervical Cancer) trial, it improved overall survival by a significant 3.7 months over platinum doublet chemotherapy alone. However, this discovery is not likely to improve the status of global cervical cancer because more than 85% of patients with cervical cancer live in low- and middle-income countries and cannot afford bevacizumab...
April 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28717260/faculty-motivation-to-mentor-students-through-undergraduate-research-programs-a-study-of-enabling-and-constraining-factors
#8
Danielle X Morales, Sara E Grineski, Timothy W Collins
Undergraduate research experiences are a "high impact" educational practice that confer benefits to students. However, little attention has been paid to understanding faculty motivation to mentor undergraduate students through research training programs, even as the number of programs has grown, requiring increasing numbers of faculty mentors. To address this, we introduce a conceptual model for understanding faculty motivation to mentor and test it by using empirical data to identify factors that enable and constrain faculty engagement in an undergraduate research program...
August 2017: Research in Higher Education
https://www.readbyqxmd.com/read/28716796/clinical-and-cost-effectiveness-of-progressive-exercise-compared-with-best-practice-advice-with-or-without-corticosteroid-injection-for-the-treatment-of-rotator-cuff-disorders-protocol-for-a-2x2-factorial-randomised-controlled-trial-the-grasp-trial
#9
Sally Hopewell, David J Keene, Michael Maia Schlüssel, Melina Dritsaki, Susan Dutton, Andrew Carr, William Hamilton, Zara Hansen, Anju Jaggi, Chris Littlewood, Hessam Soutakbar, Peter Heine, Lucy Cureton, Karen Barker, Sarah E Lamb
INTRODUCTION: Shoulder pain is very common, with around 70% of cases due to disorders of the rotator cuff. Despite widespread provision of physiotherapy, there is uncertainty about which type of exercise and delivery mechanisms are associated with best outcomes. There is also uncertainty around the long-term benefits and harms of corticosteroid injection therapy, which is often used in addition to physiotherapy. The Getting it Right: Addressing Shoulder Pain trial will assess the clinical and cost-effectiveness of individually tailored, progressive exercise compared with best practice advice, with or without corticosteroid injection, in adults with a rotator cuff disorder...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716608/opioidergic-and-dopaminergic-modulation-of-cost-benefit-decision-making-in-long-evans-rats
#10
Ileana Morales, Paul J Currie, Timothy D Hackenberg, Raúl Pastor
Eating disorders are associated with impaired decision-making and dysfunctional reward-related neurochemistry. The present study examined the potential contributions of dopamine and opioid signaling to these processes using two different decision-making tasks. In one task, Long Evans Rats chose between working for a preferred food (high-carbohydrate banana-flavored sucrose pellets) by lever pressing on a progressive-ratio schedule of reinforcement vs. obtaining less preferred laboratory chow that was concurrently available...
July 14, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28716478/-evaluation-of-practices-and-costs-of-vasectomy-french-monocentric-experience
#11
A Hourié, M Baron, J D Rebibo, A Giwerc, N Rives, L Sibert
INTRODUCTION: Since the law of 4 July 2001, vasectomy has been recognized as a method of male contraception. We report the experience of vasectomy practice in a hospital-university center. METHODS: A monocentric retrospective cohort study of 45 patients who benefited from a contraceptive vasectomy between July 2001 and May 2016. For each patient were studied: modalities of implementation, compliance with the recommendations of the 2001 law, costs and benefits generated by the intervention, the effectiveness of the gesture on the control spermograms, the satisfaction of the patients by a telephone questionnaire...
July 14, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28716195/quantitative-assessment-of-social-and-economic-impact-of-african-swine-fever-outbreaks-in-northern-uganda
#12
Erika Chenais, Sofia Boqvist, Ulf Emanuelson, Claudia von Brömssen, Emily Ouma, Tonny Aliro, Charles Masembe, Karl Ståhl, Susanna Sternberg-Lewerin
African swine fever (ASF) is one of the most important pig diseases, causing high case fatality rate and trade restrictions upon reported outbreaks. In Uganda, a low-income country with the largest pig population in East Africa, ASF is endemic. Animal disease impact is multidimensional and include social and economic impact along the value chain. In low-income settings, this impact keep people poor and push those that have managed to escape poverty back again. If the diseases can be controlled, their negative consequences can be mitigated...
September 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28716193/epidemiological-features-and-financial-loss-due-to-clinically-diagnosed-haemorrhagic-septicemia-in-bovines-in-karnataka-india
#13
G Govindaraj, P Krishnamoorthy, K R Nethrayini, R Shalini, H Rahman
The epidemiological features and financial losses due to Haemorrhagic Septicemia (HS) in bovines were studied in Karnataka state using the primary data collected from 133 clinically diagnosed HS affected farms. The various losses due to HS and the Benefit- Cost of the vaccination programme in cattle and water buffaloes were studied using mathematical models. The number of HS outbreaks were higher during the year 2002 and peaked during 2005 and thereafter declined due to targeted vaccination against HS. The morbidity and mortality risks were lower in large farms than medium and small farms, and lower in indigenous cattle compared to high yielding crossbred cattle and water buffaloes...
September 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28715054/sustainability-of-prevention-practices-at-the-workplace-safety-simplification-productivity-and-effectiveness
#14
A Messineo, M S Cattaruzza, C Prestigiacomo, F Giordano, L T Marsella
Traditional full-time employment has evolved into various types of occupational situations, and, nowadays, new work organization strategies have been developed. Previously overlooked risk factors have emerged, such as traffic accidents while commuting or during work hours, poor work organization, and detrimental lifestyles (like alcohol and substance abuse, although recent statistics seem to show a declining trend for the latter). The global scenario shows greater attention to occupational risks, but also, to the reduced degree of protection...
September 2017: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/28714729/benefits-of-open-and-high-powered-research-outweigh-costs
#15
Etienne P LeBel, Lorne Campbell, Timothy J Loving
Several researchers recently outlined unacknowledged costs of open science practices, arguing these costs may outweigh benefits and stifle discovery of novel findings. We scrutinize these researchers' (a) statistical concern that heightened stringency with respect to false-positives will increase false-negatives and (b) metascientific concern that larger samples and executing direct replications engender opportunity costs that will decrease the rate of making novel discoveries. We argue their statistical concern is unwarranted given open science proponents recommend such practices to reduce the inflated Type I error rate from ...
August 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28714710/a-relative-bilingual-advantage-in-switching-with-preparation-nuanced-explorations-of-the-proposed-association-between-bilingualism-and-task-switching
#16
Alena Stasenko, Georg E Matt, Tamar H Gollan
Bilingual language switching may increase general switching efficiency, but the evidence on this question is mixed. We hypothesized that group differences in switching might be stronger at a long cue-target interval (CTI), which may better tap general switching abilities (Yehene & Meiran, 2007). Eighty Spanish-English bilinguals and 80 monolinguals completed a color-shape switching task, and an analogous language-switching task, varying CTI (short vs. long) in both tasks. With longer preparation time (long CTI), bilinguals exhibited significantly smaller task-switching costs than monolinguals, but only in the first half of trials...
July 17, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28714678/review-of-the-fuel-saving-life-cycle-ghg-emission-and-ownership-cost-impacts-of-lightweighting-vehicles-with-different-powertrains
#17
Jason M Luk, Hyung Chul Kim, Robert De Kleine, Timothy J Wallington, Heather L MacLean
The literature analyzing the fuel saving, life cycle greenhouse gas (GHG) emission, and ownership cost impacts of lightweighting vehicles with different powertrains is reviewed. Vehicles with lower powertrain efficiencies have higher fuel consumption. Thus, fuel savings from lightweighting internal combustion engine vehicles can be higher than those of hybrid electric and battery electric vehicles. However, the impact of fuel savings on life cycle costs and GHG emissions depends on fuel prices, fuel carbon intensities and fuel storage requirements...
July 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28714533/multicenter-retrospective-study-of-neurostimulation-with-exit-of-therapy-by-explant
#18
Jason E Pope, Timothy R Deer, Steven Falowski, David Provenzano, Michael Hanes, Salim M Hayek, Jacob Amrani, Jonathan Carlson, Ioannis Skaribas, Kris Parchuri, W Porter McRoberts, Robert Bolash, Nameer Haider, Maged Hamza, Kasra Amirdelfan, Sean Graham, Corey Hunter, Eric Lee, Sean Li, Michael Yang, Lucas Campos, Shrif Costandi, Robert Levy, Nagy Mekhail
INTRODUCTION: Spinal cord stimulation (SCS) devices are cost effective and improve function as well as quality of life. Despite the demonstrated benefits of SCS, some patients have the device explanted. We are interested in exploring the patient characteristics of those explanted. METHODS: This is a retrospective chart review of neurostimulation patients who underwent explantation at 18 centers across the United States within the previous five years. RESULTS: Data from 352 patients were collected and compiled...
July 17, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28714329/synthetic-sutures-clinical-evaluation-and-future-developments
#19
Roxanna E Abhari, Joana A Martins, Hayley L Morris, Pierre-Alexis Mouthuy, Andrew Carr
Today's sutures are the result of a 4000-year innovation process with regard to their materials and manufacturing techniques, yet little has been done to enhance the therapeutic value of the suture itself. In this review, we explore the historical development, regulatory database and clinical literature of sutures to gain a fuller picture of suture advances to date. First, we examine historical shifts in suture manufacturing companies and review suture regulatory databases to understand the forces driving suture development...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28714296/-68-ga-somatostatin-analogue-pet-ct-analysis-of-costs-and-benefits-in-a-public-hospital-setting
#20
Tatiana Segard, Laurence Mja Morandeau, Elizabeth A Geelhoed, Roslyn J Francis
INTRODUCTION: Between 2009 and 2012, (68) Ga-somatostatin analogue PET-CT progressively replaced (111) In-octreotide scintigraphy for imaging neuroendocrine tumours in WA public hospitals due to published literature demonstrating improved diagnostic accuracy and increased availability. Despite significantly improved sensitivity and specificity, (68) Ga-somatostatin analogue PET is currently unfunded in Australia. This study sought to undertake cost analysis of the two modalities in a public hospital setting and to compare them with regard to patient factors such as imaging time and radiation dose...
July 17, 2017: Journal of Medical Imaging and Radiation Oncology
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