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Spondylodiscitis pet

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https://www.readbyqxmd.com/read/27671947/febrile-syndrome-of-unknown-origin-indications-for-18-f-fdg-pet-ct-in-inflammatory-and-infectious-processes
#1
J R García
Fever of unknown origin is defined as a body temperature greater than 38.3°C lasting more than three weeks for which the cause could not be found within one week of hospital admission. More than 200 causes have been reported, and these can be classified into four categories: infections, inflammatory diseases, oncologic processes, and miscellaneous conditions. Noninvasive diagnostic techniques are used in 69.2% of cases and invasive techniques in 30.8%. Structural imaging techniques show the morphological changes from infectious, inflammatory, and tumor-related processes, but they do not allow the detection of the early changes brought about by these processes...
September 23, 2016: Radiología
https://www.readbyqxmd.com/read/27390160/radionuclide-imaging-of-musculoskeletal-infection-a-review
#2
REVIEW
Christopher J Palestro
There are numerous imaging tests for diagnosing musculoskeletal infection. Radiographs are routinely performed, because even when not diagnostic, they provide an anatomic overview of the region of interest that could influence subsequent procedure selection and interpretation. MRI is sensitive and provides superb anatomic detail. Bone scintigraphy accurately diagnoses osteomyelitis in bones not affected by underlying conditions. (67)Ga is used primarily for spondylodiskitis. Although in vitro labeled leukocyte imaging is the radionuclide test of choice for complicating osteomyelitis such as diabetic pedal osteomyelitis and prosthetic joint infection, it is not useful for spondylodiskitis...
September 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/27317050/a-comparison-of-the-diagnostic-value-of-mri-and-18-f-fdg-pet-ct-in-suspected-spondylodiscitis
#3
Carolijn Smids, Ilse J E Kouijzer, Fidel J Vos, Tom Sprong, Allard J F Hosman, Jacky W J de Rooy, Erik H J G Aarntzen, Lioe-Fee de Geus-Oei, Wim J G Oyen, Chantal P Bleeker-Rovers
PURPOSE: The purpose of this study was to evaluate the diagnostic value of (18)F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT scan) and magnetic resonance imaging (MRI) in diagnosing spondylodiscitis and its complications, such as epidural and paraspinal abscesses. METHODS: From January 2006 to August 2013 patients with a clinical suspicion of spondylodiscitis, with an infection, or with fever of unknown origin were retrospectively included if (18)F-FDG-PET/CT and MRI of the spine were performed within a 2-week time span...
June 17, 2016: Infection
https://www.readbyqxmd.com/read/27199353/use-of-simultaneous-18f-fdg-pet-mri-for-the-detection-of-spondylodiskitis
#4
Jeanette Fahnert, Sandra Purz, Jan-Sven Jarvers, Christoph-Eckhard Heyde, Henryk Barthel, Patrick Stumpp, Thomas Kahn, Osama Sabri, Benjamin Friedrich
UNLABELLED: The diagnosis of spondylodiskitis is often challenging. MRI is quite sensitive but lacks specificity, and distinction from erosive osteochondritis is often difficult. We sought to assess the diagnostic value of (18)F-FDG PET combined with MRI (combined (18)F-FDG PET/MRI) in patients with suspected spondylodiskitis and an inconclusive clinical or MRI presentation. METHODS: In a prospective study, 30 patients with previous inconclusive MRI results and suspected spondylodiskitis underwent combined (18)F-FDG PET/MRI, including precontrast and postcontrast standard spine MRI sequences...
September 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/27160950/diagnostic-value-of-f-18-fdg-pet-ct-in-patients-with-spondylodiscitis-is-dual-time-point-imaging-time-worthy
#5
Burcak Yilmaz Gunes, Cetin Onsel, Kerim Sonmezoglu, Resat Ozaras, Metin Halac, Fehmi Tabak, Sait Sager, Bilgul Mete, Haluk Sayman, Bedii Kanmaz
PURPOSE: In this retrospective study, we aimed to investigate the value of FDG-PET/CT in the diagnosis of spondylodiscitis (SD), the significance of dual time point imaging (DTPI) for SD diagnosis and the worth of SUVmax data for distinguishing tuberculous vs. non-tuberculous SD. MATERIALS AND METHODS: 32 patients with suspected SD were scanned with FDG-PET/CT. For quantitative analysis maximum standardized uptake value (SUVmax) of the lesion area was measured. Nineteen patients had DTPI of FDG-PET/CT...
July 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27015880/disappearance-of-fdg-uptake-on-pet-scan-after-antimicrobial-therapy-could-help-for-the-diagnosis-of-coxiella-burnetii-spondylodiscitis
#6
Marine Gaudé, Saison Julien, Frédéric Laurent, Tristan Ferry
No abstract text is available yet for this article.
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/26897683/contribution-of-pet-imaging-to-the-diagnosis-of-septic-embolism-in-patients-with-pacing-lead-endocarditis
#7
Sana Amraoui, Ghoufrane Tlili, Manav Sohal, Benjamin Berte, Elif Hindié, Philippe Ritter, Sylvain Ploux, Arnaud Denis, Nicolas Derval, Christopher A Rinaldi, Charles Cazanave, Pierre Jais, Michel Haissaguerre, Laurence Bordenave, Pierre Bordachar
OBJECTIVES: The aim of this study was to investigate the role of 18-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) scanning in identifying septic embolism in patients with lead endocarditis. BACKGROUND: Lead endocarditis may be associated with septic embolism, in which case the administration mode, type, and duration of antibiotic therapy must be adapted. However, diagnosis can be challenging: magnetic resonance imaging (MRI) cannot be performed in the vast majority of patients with cardiac implantable electronic devices (CIEDs)...
March 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/26046885/aortic-arch-mycotic-aneurysm-due-to-scedosporium-apiospermum-reconstructed-with-homografts
#8
Arnau Blasco-Lucas, José Luis Reyes-Juárez, María Nazarena Pizzi, Eduard Permanyer, Arturo Evangelista, Manuel Galiñanes
A 39-year-old female, active parenteral drug user was diagnosed of spondylodiscitis. A computed tomography (CT) scan showed an extensive aortic arch aneurysm. A positron emission tomography (PET)-CT scan, showing significant aortic wall uptake of the tracer through the whole aortic arch and the D8-D9 intervertebral disc, allowed us to suspect an aortitis despite negative blood cultures. The aneurysm was resected and reconstructed with 2 aortic homografts. Cultures of specimens from the aortic wall were positive to the fungi Scedosporium apiospermum...
June 2015: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/25784060/-rare-metastatic-infection-sites-in-s-aureus-bacteraemia
#9
Maaike Blaauwgeers, Robin Hes
BACKGROUND: Bacteraemia caused by Staphylococcus aureus may result in metastatic infection sites. The most common types of metastatic infection are endocarditis and spondylodiscitis. Less common sites of infection can cause atypical symptoms and be a challenge to diagnose. CASE DESCRIPTION: A 23-year-old male presented at the Emergency Room with acute abdominal pain radiating to his groin area, abnormal gait and fever. Blood cultures showed S. aureus. Endocarditis was ruled out by transthoracic echocardiography...
2015: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/25017025/aseptic-lysis-l2-l3-as-complication-of-abdominal-aortic-aneurysm-repair
#10
Federico Mancini, Andrea Ascoli-Marchetti, Luca Garro, Roberto Caterini
Osteolytic vertebral erosion is usually related to tumours, spondylitis or spondylodiscitis. Few reports in the literature describe lytic lesions of anterior lumbar vertebral bodies resulting from abdominal aortic aneurysm or false aneurysm. We report a case of abdominal aortic false aneurysm that caused lytic lesions of the second and third vertebral bodies in an 80-year-old man who underwent endovascular aneurysm repair. Fluoroscopy guided biopsy excluded infection or tumour. We performed a posterior spinal fusion and decompression because of bone loss of the second and third lumbar vertebral bodies and central stenosis...
December 2014: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/24825044/spondylodiscitis-in-familial-dysautonomia-a-case-report
#11
R Ghermandi, A Mesfin, S Terzi, S Colangeli, E Zamparini, A Gasbarrini
Familial dysautomonia (FD, or Riley-Day syndrome) is a rare but fatal autosomal recessive peripheral neuropathy caused by a point mutation in I-κ-B kinase complex associated protein (IKBCAP) gene. The disease, that affects primarily people of Ashkenazi Jewish origin, prejudices the development of primary sensory neurons determining depletion of autonomic and sensory neurons. Musculoskeletal problems include: spinal deformities, foot deformities, fractures and arthopathies. In this article we review a case of a 34 years old male of non-Jewish origin affected by FD presenting L2-L3 kyphosis and inability to walk due to chronic L2-L3 spondylodiscitis not surgically treated 14 years before as acute disease...
2014: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/24469568/diagnostic-flowcharts-in-osteomyelitis-spondylodiscitis-and-prosthetic-joint-infection
#12
REVIEW
P Jutte, E Lazzeri, L M Sconfienza, V Cassar-Pullicino, A Trampuz, N Petrosillo, A Signore
Infections of the bone, spine and prosthetic joints are serious and complex conditions to diagnose and to treat. Structured diagnostic workup may very well improve the accuracy and speed of diagnosis, thereby improving the outcome since treatment may very well be more successful and less harmful if timely management is started. Literature shows no uniform advise on diagnosis. The EANM organized a consensus meeting with representatives from the involved disciplines in order to develop common flowcharts for the diagnosis of osteomyelitis, spondylodiscitis and prosthetic joint infections...
March 2014: Quarterly Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/24445277/fdg-pet-is-a-robust-tool-for-the-diagnosis-of-spondylodiscitis-a-meta-analysis-of-diagnostic-data
#13
Michael L Prodromou, Panayiotis D Ziakas, Loukia S Poulou, Petros Karsaliakos, Loukas Thanos, Eleftherios Mylonakis
PURPOSE: Spondylodiscitis is a rare infectious entity that requires multimodal diagnostic procedures. We evaluated the diagnostic performance of 18F-FDG PET on suspected spondylodiscitis based on published literature. PATIENTS AND METHODS: We searched the PubMed and EMBASE for pertinent studies up to July 2013. We implemented a patient-based meta-analysis of diagnostic data for FDG PET (the index test) against clinical, laboratory, and/or radiologic evidence of disease (the reference standard)...
April 2014: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/24189767/pyogenic-spondylodiscitis-and-osteoradionecrosis-of-the-cervico-thoracic-spine-a-rare-complication-after-surgery-and-radiation-for-hypopharyngeal-cancer
#14
Paolo Gradoni, Gabriele Oretti, Andrea Ferri, Teore Ferri
OBJECTIVE: To describe a rare case of osteoradionecrosis and pyogenic spondylodiscitis of the cervico-thoracic spine after surgery and radiotherapy for hypopharyngeal cancer. METHODOLOGY: Diagnostic clues are presented and critically discussed with particular regard to computed tomography, magnetic resonance and positron emission tomography features advising the association between and osteoradionecrosis and spondylodiscitis. RESULTS AND CONCLUSIONS: Pathogen isolation via CT-guided biopsy provided the definite diagnosis and indicated the targeted therapy...
April 2013: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/24027590/the-use-of-18-f-fdg-pet-ct-for-diagnosis-and-treatment-monitoring-of-inflammatory-and-infectious-diseases
#15
REVIEW
Andor W J M Glaudemans, Erik F J de Vries, Filippo Galli, Rudi A J O Dierckx, Riemer H J A Slart, Alberto Signore
FDG-PET, combined with CT, is nowadays getting more and more relevant for the diagnosis of several infectious and inflammatory diseases and particularly for therapy monitoring. Thus, this paper gives special attention to the role of FDG-PET/CT in the diagnosis and therapy monitoring of infectious and inflammatory diseases. Enough evidence in the literature already exists about the usefulness of FDG-PET/CT in the diagnosis, management, and followup of patients with sarcoidosis, spondylodiscitis, and vasculitis...
2013: Clinical & Developmental Immunology
https://www.readbyqxmd.com/read/24025917/18f-fluorodeoxyglucose-uptake-pattern-in-patients-with-suspected-spondylodiscitis
#16
Stefan Hungenbach, Karl-Stefan Delank, Markus Dietlein, Peer Eysel, Alexander Drzezga, Matthias C Schmidt
BACKGROUND: Infections of the spine are rare and often discovered late, but they can have a severe outcome with hospital case fatality rates of up to 17%. Efficient and early diagnosis is important, because early diagnosis and therapy improve outcome. The aim of the current study was to evaluate the clinical value of F-fluorodeoxyglucose (18F-FDG) uptake pattern in PET as a diagnostic modality for the detection of spondylodiscitis. MATERIALS AND METHODS: 18F-FDG-PET examinations of the spine were performed in 42 patients with suspected spondylodiscitis...
November 2013: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/23358410/pet-in-the-clinical-work-up-of-patients-with-spondylodiscitis-a-new-tool-for-the-clinician
#17
A Skanjeti, D Penna, A Douroukas, A Cistaro, V Arena, G Leo, G Longo, A Traverso, S Belloro, E Pelosi
AIM: The role of 18F-fluorodeoxyglucose-positron-emission tomography (FDG-PET) in the clinical management of patients with inflammatory diseases (e.g., chronic inflammatory diseases, fever of unknown origin, ostemyelitis, prosthesis infections) is still under investigation. The aim of the present study was to evaluate the usefulness of PET in the diagnostic work-up of patients with spondylodiscitis and to compare it with magnetic resonance imaging (MRI). METHODS: This retrospective study included 33 patients with suspected/confirmed spondylodiscitis...
December 2012: Quarterly Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/23349183/pet-ct-confirms-the-diagnosis-of-pyogenic-spondylodiscitis-complicated-by-psoas-abscess
#18
Jonathan M Davison, Jess A Graham, Neris M Nieves, Stephen M Yoest
No abstract text is available yet for this article.
2013: BMJ Case Reports
https://www.readbyqxmd.com/read/22820649/fdg-pet-ct-is-useful-for-the-interim-evaluation-of-response-to-therapy-in-patients-affected-by-haematogenous-spondylodiscitis
#19
Cristina Nanni, Luca Boriani, Caterina Salvadori, Eleonora Zamparini, Giada Rorato, Valentina Ambrosini, Alessandro Gasbarrini, Fabio Tumietto, Francesco Cristini, Luigia Scudeller, Stefano Boriani, Pierluigi Viale, Stefano Fanti
PURPOSE: Antibiotic therapy in patients affected by discitis is often empirical. Therefore, early evaluation of response to therapy is important. In many patients inflammatory indexes are low during all the phases of the diseases or are altered by concomitant diseases. The aim of the study was to assess the possible role of FDG PET/CT for the early evaluation of response to therapy in patients affected by infective discitis, in comparison to C-reactive protein (CRP) serum levels. METHODS: Enrolled in the study were 38 patients diagnosed with haematogenous infective discitis...
October 2012: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/22655480/the-role-of-nuclear-medicine-in-the-diagnosis-of-spondylodiscitis
#20
REVIEW
G Treglia, C Focacci, C Caldarella, M V Mattoli, M Salsano, S Taralli, A Giordano
BACKGROUND: The diagnosis of spondylodiscitis can be difficult, because the patients history, subjective symptoms and physical findings are often inconclusive, particularly in the early stages. AIM: To perform an overview on the role of nuclear medicine procedures with single photon emission tomography (SPET) and positron emission tomography (PET) tracers in the diagnosis of spondylodiscitis. MATERIALS AND METHODS: A literature review about bone scintigraphy, Gallium-67-citrate scintigraphy, labeled leukocytes scintigraphy and PET was performed...
April 2012: European Review for Medical and Pharmacological Sciences
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