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https://www.readbyqxmd.com/read/29151235/how-the-urge-to-kill-feels-articulations-of-emic-appetitive-aggression-experiences-among-former-forcefully-recruited-children-and-youth-in-the-acholi-region-of-northern-uganda
#1
Helle Harnisch, Anett Pfeiffer
Based on 10 months of fieldwork in the Acholi region of northern Uganda among youth and adults who were forcefully recruited into the Lord's Resistance Army (LRA) during the war, this article provides qualitative details to research on 'appetitive aggression.' Through two case-stories the article unfolds first person articulations of how 'appetitive aggression' is experienced as 'the urge to kill' and how it relates to the emic Acholi spiritual concept of 'cen'; a local Luo expression used to describe places and human beings possessed by evil spirits...
November 18, 2017: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/29151229/effects-of-female-sex-steroids-administration-on-pathophysiologic-mechanisms-in-traumatic-brain-injury
#2
REVIEW
Mohammad Khaksari, Zahra Soltani, Nader Shahrokhi
Secondary brain damage following initial brain damage in traumatic brain injury (TBI) is a major cause of adverse outcomes. There are many gaps in TBI research and a lack of therapy to limit debilitating outcomes in TBI or enhance the neurogenesis, despite pre-clinical and clinical research performed in TBI. Females show harmful outcomes against brain damage including TBI less than males, independent of different TBI occurrence. A significant reduction in secondary brain damage and improvement in neurologic outcome post-TBI has been reported following the use of progesterone and estrogen in many experimental studies...
November 19, 2017: Translational Stroke Research
https://www.readbyqxmd.com/read/29151198/high-substance-use-and-hiv-risk-behavior-among-young-argentine-men-who-have-sex-with-men
#3
Iván C Balán, Timothy Frasca, María A Pando, Rubén O Marone, Victoria Barreda, Curtis Dolezal, Alex Carballo-Diéguez, María M Ávila
In the United States young men who have sex with men have higher rates of substance use, higher HIV incidence, and less frequent HIV testing than their heterosexual counterparts and older MSM. Less is known about comparable populations in Latin America. As part of an epidemiological study, MSM were recruited through Respondent Driven Sampling in the metropolitan area of Buenos Aires, Argentina and answered a computerized behavioral survey. From the total of 500 MSM enrolled, a sub-sample of 233 aged 18-25 was analyzed...
November 18, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29151146/mapping-and-confirmation-of-loci-for-salt-tolerance-in-a-novel-soybean-germplasm-fiskeby-iii
#4
Tuyen D Do, Tri D Vuong, David Dunn, Scotty Smothers, Gunvant Patil, Dennis C Yungbluth, Pengyin Chen, Andrew Scaboo, Dong Xu, Thomas E Carter, Henry T Nguyen, J Grover Shannon
The confirmation of a major locus associated with salt tolerance and mapping of a new locus, which could be beneficial for improving salt tolerance in soybean. Breeding soybean for tolerance to high salt conditions is important in some regions of the USA and world. Soybean cultivar Fiskeby III (PI 438471) in maturity group 000 has been reported to be highly tolerant to multiple abiotic stress conditions, including salinity. In this study, a mapping population of 132 F2 families derived from a cross of cultivar Williams 82 (PI 518671, moderately salt sensitive) and Fiskeby III (salt tolerant) was analyzed to map salt tolerance genes...
November 18, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/29151136/whole-milk-consumption-and-risk-of-cardiovascular-disease-and-mortality-isfahan-cohort-study
#5
Mohammad Talaei, Naeimeh Hosseini, Rob M van Dam, Masoumeh Sadeghi, Shahram Oveisgharan, Minoo Dianatkhah, Nizal Sarrafzadegan
BACKGROUND: The association between milk intake and cardiovascular disease (CVD) and mortality risk is still controversial but data from Middle-Eastern populations are scarce. We aimed to study these associations in an Iranian population. METHODS: We used the Isfahan Cohort Study, a population-based prospective study of 6504 adult Iranians. In this analysis, we included 5432 participants free of CVD at baseline with at least one follow-up. Data on whole milk intake and other dietary factors were collected by a food frequency questionnaire at baseline...
November 18, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/29151122/genetic-polymorphisms-in-18-autosomal-str-loci-in-the-tibetan-population-living-in-tibet-chamdo-southwest-china
#6
Zhenghui Li, Jian Zhang, Hantao Zhang, Ziqing Lin, Jian Ye
Short tandem repeats (STRs) play a vitally important role in forensics. Population data is needed to improve the field. There is currently no large population data-based data set in Chamdo Tibetan. In our study, the allele frequencies and forensic statistical parameters of 18 autosomal STR loci (D5S818, D21S11, D7S820, CSF1PO, D2S1338, D3S1358, VWA, D8S1179, D16S539, PentaE, TPOX, TH01, D19S433, D18S51, FGA, D6S1043, D13S317, and D12S391) included in the DNATyper™19 kit were investigated in 2249 healthy, unrelated Tibetan subjects living in Tibet Chamdo, Southwest China...
November 18, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29151112/phase-difference-enhanced-magnetic-resonance-mr-imaging-padre-technique-for-the-detection-of-age-related-microstructural-changes-in-optic-radiation-comparison-with-diffusion-tensor-imaging-dti
#7
Yasuko Tatewaki, Tatsushi Mutoh, Benjamin Thyreau, Kazuko Omodaka, Takaki Murata, Atsushi Sekiguchi, Toru Nakazawa, Yasuyuki Taki
BACKGROUND The optic radiation (OR) is a white-matter bundle connecting the lateral geniculate body and the visual cortex. Phase difference-enhanced imaging (PADRE) is a new MRI technique that is able to achieve precise delineation of the OR. The aim of this study was to investigate the effect of age on the volume and signal intensity of the OR using PADRE, and to establish a volumetric reference of the OR from a healthy population, compared with diffusion tensor imaging (DTI). MATERIAL AND METHODS Thirty-nine healthy volunteers underwent MR imaging with PADRE and DTI sequences on a 3...
November 19, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29151059/genome-wide-association-study-of-telomere-length-among-south-asians-identifies-a-second-rtel1-association-signal
#8
Dayana A Delgado, Chenan Zhang, Lin S Chen, Jianjun Gao, Shantanu Roy, Justin Shinkle, Mekala Sabarinathan, Maria Argos, Lin Tong, Alauddin Ahmed, Tariqul Islam, Muhammad Rakibuz-Zaman, Golam Sarwar, Hasan Shahriar, Mahfuzar Rahman, Mohammad Yunus, Farzana Jasmine, Muhammad G Kibriya, Habibul Ahsan, Brandon L Pierce
BACKGROUND: Leucocyte telomere length (TL) is a potential biomarker of ageing and risk for age-related disease. Leucocyte TL is heritable and shows substantial differences by race/ethnicity. Recent genome-wide association studies (GWAS) report ~10 loci harbouring SNPs associated with leucocyte TL, but these studies focus primarily on populations of European ancestry. OBJECTIVE: This study aims to enhance our understanding of genetic determinants of TL across populations...
November 18, 2017: Journal of Medical Genetics
https://www.readbyqxmd.com/read/29151052/prevalence-of-health-services-usage-and-associated-factors-in-the-amazon-region-of-brazil-a-population-based-cross-sectional-study
#9
Maria Elizete A Araujo, Marcus T Silva, Tais F Galvao, Mauricio G Pereira
OBJECTIVES: To estimate the prevalence of healthcare use and associated factors in the Manaus metropolitan region and to describe the reasons for lack of access. DESIGN: Cross-sectional population-based study. SETTING: A survey conducted between May and August of 2015 in eight cities from Manaus metropolitan region, Amazonas, Brazil. PARTICIPANTS: 4001 adults ≥18 years of age. PRIMARY OUTCOMES MEASURES: Physician visits, dentist visits and hospitalisations in the last 12 months were the primary outcomes...
November 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/29151046/the-association-between-gastro-oesophageal-reflux-disease-and-subsequent-rheumatoid-arthritis-occurrence-a-nested-case-control-study-from-taiwan
#10
Herng-Ching Lin, Sudha Xirasagar, Cha-Ze Lee, Chung-Chien Huang, Chao-Hung Chen
OBJECTIVE: Gastro-oesophageal reflux disease (GORD) is a common comorbidity among patients with rheumatoid arthritis (RA). While GORD has been attributed to the antirheumatic medications, no studies of human cohorts have investigated a link between GORD and RA. This study investigates whether GORD is associated with a subsequent RA diagnosis over a 5-year follow-up using a population-based dataset. SETTING: Taiwan PARTICIPANTS: We used data from the Taiwan Longitudinal Health Insurance Database...
November 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/29151045/the-physical-and-mental-health-problems-of-refugee-and-migrant-fathers-findings-from-an-australian-population-based-study-of-children-and-their-families
#11
Rebecca Giallo, Elisha Riggs, Claire Lynch, Dannielle Vanpraag, Jane Yelland, Josef Szwarc, Philippa Duell-Piening, Lauren Tyrell, Sue Casey, Stephanie Janne Brown
OBJECTIVES: The aim of this study was to report on the physical and mental health of migrant and refugee fathers participating in a population-based study of Australian children and their families. DESIGN: Cross-sectional survey data drawn from a population-based longitudinal study when children were aged 4-5 years. SETTING: Population-based study of Australian children and their families. PARTICIPANTS: 8137 fathers participated in the study when their children were aged 4-5 years...
November 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/29151028/variations-in-use-of-optimal-medical-therapy-in-patients-with-nonobstructive-coronary-artery-disease-a-population-based-study
#12
Adam Oxner, Gabby Elbaz-Greener, Feng Qui, Shannon Masih, Nevena Zivkovic, Sami Alnasser, Asim N Cheema, Harindra C Wijeysundera
BACKGROUND: There is a paucity of data on the need for optimal medical therapy (OMT) in nonobstructive coronary artery disease . We sought to understand if there was variation in the use of OMT between hospitals for patients with nonobstructive coronary artery disease, the factors associated with such variation, and its clinical consequences. METHODS AND RESULTS: Using a population-level clinical registry in Ontario, Canada, we identified all patients >66 years undergoing coronary angiography for the indication of stable angina, who had nonobstructive coronary artery disease between November 1, 2010, and October 31, 2013...
November 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29150991/population-based-differences-in-immune-system-response-contribute-to-an-increased-risk-of-schizophrenia-in-african-migrants
#13
Milica J Nesic, Nadja P Maric
Among the highest incidences of schizophrenia is the one documented in second-generation migrants of African descent in the Western countries. Interestingly, people of African and European ancestry demonstrate significant genetic-based differences in immune system regulation and response. As a result, the pro-inflammatory phenotype is more pronounced in people of African descent than it is in Europeans. At the same time, the role of the immune system in the etiology of schizophrenia is gaining increased recognition...
November 18, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/29150854/rhinitis-and-its-impact-on-quality-of-life-in-swimmers
#14
Pavol Surda, Matus Putala, Pavel Siarnik, Abigail Walker, Ana Bernic, Wytske Fokkens
INTRODUCTION: Limited data suggest that swimmers might be affected by rhinitis significantly more often than the general population. This can have impact on quality of life but also on performance. The aim of the present study was to determine the prevalence and impact of QOL of rhinitis in swimming compared to non-swimming athletes and controls. MATERIALS AND METHODS: This was an observational case control, questionnaire based study involving elite (n=101) and non-elite swimming athletes (n=107), non-swimming athletes (n = 38) and sex and age-matched controls (n = 50)...
November 18, 2017: Allergy
https://www.readbyqxmd.com/read/29150853/poor-agreement-in-questionnaire-based-diagnostic-criteria-for-adult-atopic-dermatitis-is-a-challenge-when-examining-cardiovascular-comorbidity
#15
Yuki M F Andersen, Alexander Egeberg, Carsten R Hamann, Lone Skov, Gunnar H Gislason, Tea Skaaby, Allan Linneberg, Jacob P Thyssen
BACKGROUND: The association between atopic dermatitis (AD) and cardio-metabolic risk factors is not yet established. Furthermore, no validated questionnaire-based method of identifying adults with AD is currently available. OBJECTIVES: To assess the cardio-metabolic risk in adults with a history of AD by using three different questionnaire-based diagnostic criteria. METHODS: We utilized data from a general population study including questionnaire data and objective measurements of 9,656 Danish adults...
November 18, 2017: Allergy
https://www.readbyqxmd.com/read/29150846/cancer-stem-cells-as-targets-for-immunotherapy
#16
REVIEW
Amy S Codd, Takayuki Kanaseki, Toshihiko Torigo, Zsuzsanna Tabi
Current cancer therapies target the bulk of the tumour, while a population of highly resistant tumour cells may be able to repopulate the tumour and metastasise to new sites. Cancer cells with such stem cell-like characteristics can be identified based on their phenotypic and/or functional features which may open up ways for their targeted elimination. In this review we discuss potential off-target effects of inhibiting cancer stem-cell self-renewal pathways on immune cells, and summarise some recent immunological studies specifically targeting cancer stem cells based on their unique antigen expression...
November 18, 2017: Immunology
https://www.readbyqxmd.com/read/29150783/incidence-of-non-physiologically-complex-surgical-procedures-performed-in-children-an-ontario-population-based-study-of-health-administrative-data
#17
James D O'Leary, Franklin Dexter, David Faraoni, Mark W Crawford
PURPOSE: Quantification of surgical procedures undertaken by hospitals is necessary for informing resource allocation and modelling healthcare services. Our objective was to quantify the incidence, similarity, and diversity of non-physiologically complex surgical procedures performed at pediatric specialist hospitals and other hospitals performing pediatric surgery. METHODS: We conducted a population-based cohort study of children aged 28 days to 18 yr who underwent surgery in the province of Ontario from 2007 to 2015 using healthcare administrative databases...
November 17, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29150721/adaptive-snp-set-association-testing-in-generalized-linear-mixed-models-with-application-to-family-studies
#18
Jun Young Park, Chong Wu, Saonli Basu, Matt McGue, Wei Pan
In genome-wide association studies (GWAS), it has been increasingly recognized that, as a complementary approach to standard single SNP analyses, it may be beneficial to analyze a group of functionally related SNPs together. Among the existent population-based SNP-set association tests, two adaptive tests, the aSPU test and the aSPUpath test, offer a powerful and general approach at the gene- and pathway-levels by data-adaptively combining the results across multiple SNPs (and genes) such that high statistical power can be maintained across a wide range of scenarios...
November 17, 2017: Behavior Genetics
https://www.readbyqxmd.com/read/29150678/dog-ownership-and-the-risk-of-cardiovascular-disease-and-death-a-nationwide-cohort-study
#19
Mwenya Mubanga, Liisa Byberg, Christoph Nowak, Agneta Egenvall, Patrik K Magnusson, Erik Ingelsson, Tove Fall
Dogs may be beneficial in reducing cardiovascular risk in their owners by providing social support and motivation for physical activity. We aimed to investigate the association of dog ownership with incident cardiovascular disease (CVD) and death in a register-based prospective nation-wide cohort (n = 3,432,153) with up to 12 years of follow-up. Self-reported health and lifestyle habits were available for 34,202 participants in the Swedish Twin Register. Time-to-event analyses with time-updated covariates were used to calculate hazard ratios (HR) with 95% confidence intervals (CI)...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29150534/migration-and-cardiovascular-disease-risk-among-ghanaian-populations-in-europe-the-rodam-study-research-on-obesity-and-diabetes-among-african-migrants
#20
Daniel Boateng, Charles Agyemang, Erik Beune, Karlijn Meeks, Liam Smeeth, Matthias Schulze, Juliet Addo, Ama de-Graft Aikins, Cecilia Galbete, Silver Bahendeka, Ina Danquah, Peter Agyei-Baffour, Ellis Owusu-Dabo, Frank P Mockenhaupt, Joachim Spranger, Andre P Kengne, Diederick E Grobbee, Karien Stronks, Kerstin Klipstein-Grobusch
BACKGROUND: For migrant populations from sub-Saharan Africa, adverse cardiovascular disease (CVD) risk factors have been observed to be higher than found in their home country-based counterparts or among the host populations in high-income countries. Differences in absolute overall CVD risk, however, remain largely unexplained. We, therefore, predicted the differences in 10-year CVD risk among sub-Saharan African migrants (Ghanaians) living in 3 European cities and Ghana. METHODS AND RESULTS: For 3864 subjects aged 40 to 70 years from the multicenter RODAM study (Research on Obesity and Diabetes Among African Migrants) conducted among Ghanaian adults residing in rural and urban Ghana and 3 European cities (Amsterdam, Berlin, and London), 10-year risk of CVD was estimated using the Pooled Cohort Equations with estimates ≥7...
November 2017: Circulation. Cardiovascular Quality and Outcomes
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