keyword
https://read.qxmd.com/read/37378199/a-case-of-euglycemic-diabetic-ketoacidosis-dka-influenza-and-a-dipeptidyl-peptidase-4-dpp-4-inhibitor
#21
Su Hyun Jeong, Merica Vorachitti, Fernando Fuentes
A subclass of diabetic ketoacidosis (DKA) is euglycemic DKA, characterized by the same traits of ketoacidosis and low bicarbonate levels. However, the condition differs from classic DKA because of its normoglycemic levels. Euglycemic DKA was once thought to be incredibly rare, but its incidence has been on the rise with the widespread use of sodium-glucose-cotransporter-2 (SGLT2) inhibitors and other newer anti-diabetic medications. The disorder is not fully understood and is often missed when presenting because of the non-elevated blood sugars...
May 2023: Curēus
https://read.qxmd.com/read/37363439/diabetes-mellitus-type-1-presenting-in-the-setting-of-diabetic-ketoacidosis-and-acute-sars-cov-2-infection-in-pregnancy
#22
George A Stamatiades, Francesca Galbiati, Alison Conway Fitzgerald, Marie E McDonnell, Sarah C Lassey, Nadine E Palermo
BACKGROUND/OBJECTIVE: Diabetic ketoacidosis (DKA) during pregnancy is an obstetric emergency associated with a higher rate of maternofetal morbidity and mortality. Pregnancy itself is a ketosis-prone state and several unique mechanisms predispose to the development of insulin resistance, which can be further exacerbated by acute stressors such as infection. Thus, pregnant patients who additionally contract COVID-19 may be at an even higher risk of development of DKA. CASE REPORT: A 32-year-old patient, with no prior history of impaired glucose tolerance, presented at 27 weeks of gestation with a 3-day history of shortness of breath, congestion, loss of taste and smell, polyuria, and polydipsia...
April 14, 2023: AACE Clinical Case Reports
https://read.qxmd.com/read/37248600/-clinical-analysis-of-17-adult-patients-with-fulminant-type-1-diabetes-mellitus
#23
JOURNAL ARTICLE
Hong-Ping Gong, Yan Ren, Pan-Pan Zha, Da-Wei Chen, Yun Gao, Hui Huang, Chun Wang
OBJECTIVE: To explore the clinical characteristics of adult patients with fulminant type 1 diabetes mellitus (FT1DM), a specific subtype of type 1 diabetes mellitus (T1DM). METHODS: We collected the clinical data of patients who were admitted to West China Hospital, Sichuan University in 2010-2019 for FT1DM and type 1 diabetes mellitus (T1DM) presenting with diabetic ketoacidosis (DKA) at the onset. In addition, all the FT1DM patients were followed up. RESULTS: A total of 70 patients presenting with DKA at the onset of T1DM were admitted to and received treatment at West China Hospital in 2010-2019...
May 2023: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://read.qxmd.com/read/37233404/clinical-analysis-of-diabetes-in-pregnancy-with-stillbirth
#24
JOURNAL ARTICLE
Zhenyu Wang, Jia Chen, Tuhong Long, Lixuan Liang, Caijuan Zhong, Yingtao Li
We analyzed the clinical characteristics of patients with diabetes in pregnancy (DIP) associated with stillbirth and explored strategies to reduce its incidence. We retrospectively analyzed 71 stillbirths associated with DIP (group A) and 150 normal pregnancies (group B) during 2009 to 2018. The incidence of the following was higher in group A (P < .05): hypertensive disorders (38.03% vs 6.00%), placenta previa (14.08% vs 2.67%), placental abruption (5.63% vs 0.67%), fetal malformation (8.45% vs 0...
May 26, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37223178/diabetic-ketoacidosis-complicated-by-thrombotic-thrombocytopenic-purpura-a-rare-association
#25
Chinanu I Nwankwo, Kemar A Samuels, Akata Abung, Adetola F Oshikoya, Danish Waqar, Adekunle E Omole
Thrombotic thrombocytopenic purpura (TTP) is a rare and potentially life-threatening blood disorder caused by a deficiency or dysfunction of ADAMTS13 and can occur secondary to various conditions, including autoimmune diseases, infections, medications, pregnancy, and malignancies. Diabetic ketoacidosis (DKA) inducing TTP is uncommon and not widely reported in the literature. Herein, we report a case of TTP induced by DKA in an adult patient. His clinical picture, serological, and biochemical results confirmed the diagnosis of TTP induced by DKA, and his clinical course did not improve despite normalization of glucose level, plasmapheresis, and aggressive management...
April 2023: Curēus
https://read.qxmd.com/read/37082120/case-report-fulminant-type-1-diabetes-following-paucisymptomatic-sars-cov-2-infection-during-late-pregnancy
#26
Lingling Zhou, Huanjia Qu, Qiuling Zhang, Jinhua Hu, Lan Shou
BACKGROUND: Dysregulation of glucose metabolism has been linked to SARS-CoV-2 infection. In addition, the occurrence of new onset diabetes mellitus, including fulminant type 1 diabetes, has been reported after SARS-CoV-2 infection or vaccination. METHODS AND RESULTS: A young Chinese woman in her last trimester of pregnancy presented with an abrupt progression of hyperglycemia and ketoacidosis, but with a near-normal glycohemoglobin level following paucisymptomatic SARS-CoV-2 infection...
2023: Frontiers in Endocrinology
https://read.qxmd.com/read/36937003/stress-induced-diabetic-ketoacidosis-in-concurrent-ectopic-pregnancy-a-case-report
#27
Adam D Elwood, Neeti Misra
Ectopic pregnancy occurs in 1-2% of all pregnancies. The majority occur in the fallopian tube, requiring intervention in the form of methotrexate or surgery. Ruptured ectopic pregnancies can lead to hemodynamic instability, requiring immediate surgical intervention. In the case reported here, the patient presented in diabetic ketoacidosis with a pregnancy of unknown location. Upon further evaluation she was found to have a ruptured ectopic pregnancy and was taken to the operating room for surgical management...
March 2023: Case Reports in Women's Health
https://read.qxmd.com/read/36924086/real-world-use-of-control-iq%C3%A2-technology-automated-insulin-delivery-in-pregnancy-a-case-series-with-qualitative-interviews
#28
JOURNAL ARTICLE
Xinye Serena Wang, Amy D Dunlop, Julie A McKeen, Denice S Feig, Lois E Donovan
BACKGROUND: Most commercially available automated insulin delivery (AID) systems are not approved for pregnancy use. Information regarding use of the Tandem t:slim X2 insulin pump with Control-IQ™ technology in pregnancy is lacking. AIMS: This case series aimed to explore glycaemic and qualitative experiences of four early adopters of Control-IQ technology in pregnancy. METHODS: Participants used Control-IQ technology in pregnancy and postpartum and consented to analysis of glycaemic data and semi-structured interviews...
March 16, 2023: Diabetic Medicine: a Journal of the British Diabetic Association
https://read.qxmd.com/read/36819426/maternal-outcomes-among-pregnant-women-diagnosed-with-covid-19
#29
JOURNAL ARTICLE
Ahlam Al-Zahrani, Latifah Alanazi, Hala Thabet, Faiz Alenezi
BACKGROUND: COVID-19 has the potential development of negative maternal outcomes for pregnant women. The risk of contracting COVID-19 is high as pregnancy alters the maternal immune system. Therefore, this study aims to assess maternal outcomes among pregnant women with COVID-19 in the Kingdom of Saudi Arabia. METHODS: A retrospective study was conducted in three hospitals during the pandemic over four months, from the beginning of December 2019 until the end of March 2020...
January 2023: Curēus
https://read.qxmd.com/read/36819400/empagliflozin-associated-euglycemic-diabetic-ketoacidosis-in-a-patient-with-type-2-diabetes-mellitus
#30
Sukhjinder Chauhan, AndreyI Manov, Gundip S Dhillon, Pinak Shah
Euglycemic diabetic ketoacidosis (euDKA) is an uncommon condition, which is characterized by an elevated anion gap metabolic acidosis with ketonemia/ketonuria, in the presence of normal blood glucose levels. Common risk factors for the development of this condition include pregnancy, prolonged fasting, acute pancreatitis, and bariatric surgery. Sodium-glucose cotransporter-2 (SGLT-2) inhibitors have been identified as a rare cause of euDKA. A recent literature review on PubMed found only 86 case reports of euDKA secondary to SGLT inhibitors published in the medical literature up to December 2022...
January 2023: Curēus
https://read.qxmd.com/read/36792143/diabetic-ketoacidosis-in-pregnancy
#31
JOURNAL ARTICLE
Hossam Mohamed Abd-Elnaby Ali, Nasreen Syeda
The clinical presentation of diabetic ketoacidosis (DKA) includes nausea, vomiting, thirst, polyuria, polydipsia, abdominal pain, tachypnoea, and change in mental status in cases of severe DKA. DKA is similar in pregnant and non-pregnant women, but in pregnant women it can be seen at lower serum glucose levels and symptoms may develop more rapidly. Most, but not all, cases occur in the second or third trimester.DKA results in reduction in uteroplacental blood flow due to osmotic diuresis, and also in metabolic abnormalities (maternal acidosis, hyperglycaemia, electrolyte imbalance), resulting in fetal hypoxaemia and acidosis...
February 15, 2023: BMJ Case Reports
https://read.qxmd.com/read/36753706/disparities-in-continuous-glucose-monitoring-use-among-women-of-reproductive-age-with-type-1-diabetes-in-the-t1d-exchange
#32
JOURNAL ARTICLE
Kartik K Venkatesh, Camille E Powe, Elizabeth Buschur, Jiqiang Wu, Mark B Landon, Steven Gabbe, Kajal Gandhi, William A Grobman, Naleef Fareed
We identified characteristics associated with continuous glucose monitoring (CGM) use in women of reproductive age with type 1 diabetes (T1D) in the T1D Exchange clinic registry from 2015 to 2018. Among 6643 assessed women, the frequency of CGM increased from 2015 to 2018 (20.6% vs. 30.0%; adjusted odds ratios [aOR]: 1.72; confidence interval [95% CI]: 1.51-1.95) and was more likely with recent pregnancy (45.3% vs. 25.8%; aOR: 1.63; 95% CI: 1.23-2.16). Non-Hispanic Black and Hispanic race and ethnicity, younger age, lower educational attainment, lower income, and Medicaid insurance were associated with lower odds of CGM...
February 8, 2023: Diabetes Technology & Therapeutics
https://read.qxmd.com/read/36689144/euglycemic-diabetic-ketoacidosis-caused-by-alcoholic-pancreatitis-and-starvation-ketosis
#33
JOURNAL ARTICLE
Hye Jeong Han, Allison E Cole, Ashish Verma
Starvation ketosis and pancreatitis are uncommon and underrecognized etiologies of euglycemic diabetic ketoacidosis (DKA). Euglycemic DKA is associated commonly with pregnancy, use of insulin en route to the hospital, and use of sodium-glucose cotransporter-2 (SGLT-2) inhibitors. A 58-year-old male with past medical history of type II diabetes mellitus and alcoholism presented with chief complaint of nausea, vomiting, and poor oral intake for several weeks. Despite extensive history of diabetes and no recent SGLT-2 inhibitor use, his labs were consistent with euglycemic DKA...
April 2023: Journal of General Internal Medicine
https://read.qxmd.com/read/36657054/management-of-diabetic-ketoacidosis-in-pregnancy
#34
JOURNAL ARTICLE
Nicholas R Spencer, Shannon M Clark, Hassan M Harirah
Diabetic ketoacidosis (DKA) is a rare, but potentially life-threatening complication of diabetes. Certain physiological changes during pregnancy predispose pregnant individuals to developing DKA. Early recognition and aggressive treatment are essential to avoid maternal and fetal morbidity and mortality. Although laboratory values can help to support, pregnant patients with DKA may not meet the usual criteria and the diagnosis can be made clinically. The key components to treatment include volume replacement, insulin infusion, correction of serum potassium, and fetal monitoring...
March 1, 2023: Clinical Obstetrics and Gynecology
https://read.qxmd.com/read/36594778/what-s-new-in-the-management-of-type-1-diabetes-in-pregnancy
#35
REVIEW
Tara TM Lee, Helen R Murphy
Type 1 diabetes in pregnancy is associated with an increased risk of complications for both mother and fetus. However, managing glycaemia during pregnancy to reduce these risks is challenging, owing to changes in insulin resistance with advancing gestation, as well as increased daily variation in insulin pharmacokinetics. These factors can add significant psychological and daily self-care burden to mothers during what may already be an anxious time. Increasingly, diabetes technologies are being used during pregnancy to improve and facilitate diabetes self-care...
December 2, 2022: British Journal of Hospital Medicine
https://read.qxmd.com/read/36593615/unexpected-case-of-postnatal-pancreatitis-first-presentation-of-autoimmune-diabetes
#36
JOURNAL ARTICLE
Zi Xi Poo, Wen Shan Sim, Lay Kok Tan
Gestational diabetes mellitus (GDM) is defined as the first onset of glucose intolerance in pregnancy without prior known diabetes. While it is commonly associated with metabolic risk factors such as obesity and hypertension, a small percentage of women with GDM have underlying autoimmune causes, with presence of islet-cell antibodies resulting in autoimmune-mediated destruction of the pancreas. We present a case of idiopathic postpartum pancreatitis precipitating fulminant diabetic ketoacidosis in a patient with otherwise well-controlled GDM during pregnancy, and subsequent findings of positive anti-glutamic acid decarboxylase antibody...
December 7, 2022: BMJ Case Reports
https://read.qxmd.com/read/36575901/metformin-brains-aims-pharmacological-prescribing-principles-of-commonly-prescribed-top-100-drugs-education-and-discussion
#37
REVIEW
Joshua Koslover, Deborah Bruce, Shivani Patel, Andrew J Webb
We review pharmacological/prescribing principles relating to metformin according to our mnemonic framework: 'BRAINS & AIMS' (Benefits, Risks, Adverse Effects, Interactions, Necessary prophylaxis, Susceptibilities, Administering, Informing, Monitoring and Stopping): Benefits: Metformin's licensed uses: Type 2 diabetes mellitus (T2DM) treatment, reduction in risk or delay of onset. No clear evidence metformin influences patient-important outcomes [Cochrane Review (2020) of 18 RCTs (n = 10 680)]...
March 2023: British Journal of Clinical Pharmacology
https://read.qxmd.com/read/36540586/association-of-serum-magnesium-with-insulin-indices-in-patients-with-type-2-diabetes-mellitus
#38
EDITORIAL
Santhanam Kuppusamy, Raju Dhanasinghu, Varatharajan Sakthivadivel, Ariyanachi Kaliappan, Archana Gaur, Yuvaraj Balan, Lakshmi Jyothi Tadi, Raja Sundaramurthy
Introduction: Magnesium has a direct impact on glucose metabolism since it is a cofactor for numerous energy-metabolizing enzymes. Hypomagnesemia has been linked to poor glycemic control and a range of diabetes-related long-term complications. This study aimed to assess the association between blood magnesium levels and insulin sensitivity indices in patients with type 2 diabetes mellitus (T2DM). Material and methods: Two hundred newly diagnosed T2DM patients aged over 40 years were recruited after excluding those with a history of heart failure, kidney illness, liver disease, hypothyroidism, ascites, pregnancy, tumors, and complications such as diabetic ketoacidosis...
September 2022: Mædica
https://read.qxmd.com/read/36483858/euglycemic-diabetic-ketoacidosis-and-covid-19-management-in-a-term-pregnant-patient-a-case-report
#39
Fatemeh Mohammadzade, Behnaz Khodabakhshi, Elahe Amiri, Amir Bigdeli, Fahimeh Abdollahi, Alireza Fatemi
In this case report, we report a Covid-19 infected female patient with gestational diabetes mellitus with primary manifestation of ketoacidosis at term pregnancy and discuss the management challenges with euglycemia and a high ketone burden.
December 2022: Clinical Case Reports
https://read.qxmd.com/read/36432552/dietary-advice-to-support-glycaemic-control-and-weight-management-in-women-with-type-1-diabetes-during-pregnancy-and-breastfeeding
#40
REVIEW
Lene Ringholm, Sidse Kjærhus Nørgaard, Ane Rytter, Peter Damm, Elisabeth Reinhardt Mathiesen
In women with type 1 diabetes, the risk of adverse pregnancy outcomes, including congenital anomalies, preeclampsia, preterm delivery, foetal overgrowth and perinatal death is 2-4-fold increased compared to the background population. This review provides the present evidence supporting recommendations for the diet during pregnancy and breastfeeding in women with type 1 diabetes. The amount of carbohydrate consumed in a meal is the main dietary factor affecting the postprandial glucose response. Excessive gestational weight gain is emerging as another important risk factor for foetal overgrowth...
November 17, 2022: Nutrients
keyword
keyword
78695
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.