Trinidad Valenzuela, Jeff S Coombes, Teresa Liu-Ambrose, Yorgi Mavros, Nicole Kochan, Perminder S Sachdev, Jeffrey Hausdorff, Emily C Smith, Matthew Hollings, Tess C Hawkins, Nicholas J Ashley, Natan Feter, Guy C Wilson, Isabel Hui En Shih, Yareni Guerrero, Jiyang Jiang, Wei Wen, Tom Bailey, Dorthe Stensvold, Ulrik Wisløff, Ryan S Falck, Maria Fiatarone Singh
INTRODUCTION: Epidemiological evidence suggests that both poor cardiovascular fitness and low muscle mass or strength markedly increase the rate of cognitive decline and incident dementia in older adults. Results from exercise trials for the improvement of cognition in older adults with mild cognitive impairment (MCI) have reported mixed results. This is possibly due to insufficient exercise intensities. The aim of the Balance, Resistance, And INterval (BRAIN) Training Trial is to determine the effects of two forms of exercise, high-intensity aerobic interval training (HIIT) and high-intensity power training (POWER) each compared with a sham exercise control group on cognition in older adults with MCI...
December 20, 2022: BMJ Open