keyword
https://read.qxmd.com/read/38532434/optimization-of-cardiopulmonary-bypass-prime-fluid-to-preserve-microcirculatory-perfusion-during-on-pump-coronary-artery-bypass-graft-surgery-prime-study-protocol-for-a-double-blind-randomized-trial
#1
JOURNAL ARTICLE
Anne M Beukers, Carolien S E Bulte, Ruben J Bosch, Susanne Eberl, Charissa E van den Brom, Stephan A Loer, Alexander B A Vonk
BACKGROUND: Acute microcirculatory perfusion disturbances and organ edema are important factors leading to organ dysfunction during cardiac surgery with cardiopulmonary bypass (CPB). Priming of the CPB system with crystalloid or colloid fluids, which inevitably leads to hemodilution, could contribute to this effect. However, there is yet no optimal evidence-based strategy for this type of priming. Hence, we will investigate different priming strategies to reduce hemodilution and preserve microcirculatory perfusion...
March 26, 2024: Trials
https://read.qxmd.com/read/38531186/effect-of-dietary-electrolyte-balance-and-arginine-to-lysine-ratio-on-hematological-antioxidant-and-immunological-traits-in-dual-purpose-breeding-hens-under-cyclic-heat-stress-condition
#2
JOURNAL ARTICLE
Youssef A Attia, Ahmed A Abdallah, Fulvia Bovera, Abd El-Hamid E Abd El-Hamid, Asmaa Sh El-Naggar, Rashed A Alhotan, Vincenzo Tufarelli, Reda M Zaki
A total of 245 hens and 35 cocks (32 weeks age) were assigned to seven treatment groups (five replicates with seven hens and one cock) to investigate the effect of dietary electrolyte balance (DEB) and arginine to lysine ratio (Arg/Lys) on birds' physiological and biochemical traits under cyclic heat stress (CHS) condition. Birds were housed in an environmentally controlled facility having four sectors. The first group (positive control, PC) was kept under thermoneutral conditions and fed diet with DEB of 180 mEq and Arg/Lys of 1...
March 21, 2024: Journal of Thermal Biology
https://read.qxmd.com/read/38530649/iatrogenic-hyperchloremia-an-overview-in-hospitalized-patients-for-pharmacists
#3
JOURNAL ARTICLE
Amoreena Most, Sarah Nordbeck, Nicholas Farina
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: The purpose of this therapeutic update is to provide pharmacists with a general overview of the pathophysiology of hyperchloremia and describe strategies to help prevent development of this electrolyte abnormality in hospitalized patients...
March 26, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38526761/intraoperative-kidney-replacement-therapy-in-acute-liver-failure
#4
JOURNAL ARTICLE
Daniel Henderson, Anish Gupta, Shina Menon, Akash Deep
Paediatric acute liver failure (PALF) is often characterised by its rapidity of onset and potential for significant morbidity and even mortality. Patients often develop multiorgan dysfunction/failure, including severe acute kidney injury (AKI). Whilst the management of PALF focuses on complications of hepatic dysfunction, the associated kidney impairment can significantly affect patient outcomes. Severe AKI requiring continuous kidney replacement therapy (CKRT) is a common complication of both PALF and liver transplantation...
March 25, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38526682/dilute-aqueous-aprotic-electrolyte-towards-robust-zn-ion-hybrid-supercapacitor-with-high-operation-voltage-and-long-lifespan
#5
JOURNAL ARTICLE
Shuilin Wu, Yibing Yang, Mingzi Sun, Tian Zhang, Shaozhuan Huang, Daohong Zhang, Bolong Huang, Pengfei Wang, Wenjun Zhang
With the merits of the high energy density of batteries and power density of supercapacitors, the aqueous Zn-ion hybrid supercapacitors emerge as a promising candidate for applications where both rapid energy delivery and moderate energy storage are required. However, the narrow electrochemical window of aqueous electrolytes induces severe side reactions on the Zn metal anode and shortens its lifespan. It also limits the operation voltage and energy density of the Zn-ion hybrid supercapacitors. Using 'water in salt' electrolytes can effectively broaden their electrochemical windows, but this is at the expense of high cost, low ionic conductivity, and narrow temperature compatibility, compromising the electrochemical performance of the Zn-ion hybrid supercapacitors...
March 25, 2024: Nano-Micro Letters
https://read.qxmd.com/read/38521862/ultra-fast-green-hydrogen-production-from-municipal-wastewater-by-an-integrated-forward-osmosis-alkaline-water-electrolysis-system
#6
JOURNAL ARTICLE
Gabriela Scheibel Cassol, Chii Shang, Alicia Kyoungjin An, Noman Khalid Khanzada, Francesco Ciucci, Alessandro Manzotti, Paul Westerhoff, Yinghao Song, Li Ling
Recent advancements in membrane-assisted seawater electrolysis powered by renewable energy offer a sustainable path to green hydrogen production. However, its large-scale implementation faces challenges due to slow power-to-hydrogen (P2H) conversion rates. Here we report a modular forward osmosis-water splitting (FOWS) system that integrates a thin-film composite FO membrane for water extraction with alkaline water electrolysis (AWE), denoted as FOWSAWE . This system generates high-purity hydrogen directly from wastewater at a rate of 448 Nm3  day-1  m- 2 of membrane area, over 14 times faster than the state-of-the-art practice, with specific energy consumption as low as 3...
March 23, 2024: Nature Communications
https://read.qxmd.com/read/38518838/environmental-toxicants-and-nephrotoxicity-implications-on-mechanisms-and-therapeutic-strategies
#7
REVIEW
Rachna Yadav, Dinesh Kumar, Jiten Singh, Ashok Jangra
Kidneys are one of the most important organs in the human body. In addition to filtering 200 liters of fluid every 24hours, the kidney also regulates acid-base balance, maintains electrolyte balance, and removes waste and toxicants from the body. Nephrotoxicity is the term used to describe the deterioration of kidney function caused by the harmful effects of medications and chemicals found in the environment. Exposure to environmental toxicants is an inevitable side effect of the world's increasing industrialization and it is even more prevalent in underdeveloped nations...
March 20, 2024: Toxicology
https://read.qxmd.com/read/38511624/influences-of-dietary-reduced-nitrogen-n-and-phosphorus-p-on-chemical-body-composition-n-and-p-retention-and-health-traits-of-contemporary-barrows
#8
JOURNAL ARTICLE
Elisabeth Beckmüller, Jeannette Kluess, Liane Hüther, Susanne Kersten, Mareike Kölln, Christian Visscher, Sven Dänicke, Angelika Grümpel-Schlüter
Farmgate balances are used as a tool for monitoring nutrient surpluses at farm level. In Germany, preparation of farmgate balances is legally mandatory and also requires data on chemical body composition, especially concentration of nitrogen (N) and phosphorus (P), of farm animals. It is well known that increased N and P efficiency results in lowered N and P excretions with the manure and therefore mitigates negative consequences of high N and P release into the environment (e.g. eutrophication of surface waters), especially in areas with high livestock density...
March 21, 2024: Archives of Animal Nutrition
https://read.qxmd.com/read/38509690/water-and-salt-concentration-dependent-electrochemical-performance-of-hydrogel-electrolytes-in-zinc-ion-batteries
#9
JOURNAL ARTICLE
Di Zhu, Jing Li, Zhi Zheng, Songbo Ye, Yuqi Pan, Jiacheng Wu, Fangxin She, Leo Lai, Zihan Zhou, Jiaxiang Chen, Hao Li, Li Wei, Yuan Chen
Zinc-ion batteries (ZIBs) are promising energy storage devices with safe, nonflammable electrolytes and abundant, low-cost electrode materials. Their practical applications are hampered by various water-related undesirable reactions, such as the hydrogen evolution reaction (HER), corrosion of zinc metal, and water-induced decay of cathode materials. Polymer hydrogel electrolytes were used to control these reactions. However, salt, water, and polymeric backbones intervene in polymer hydrogels, and currently, there are no systematic studies on how salt and water concentrations synergistically affect polymer hydrogels' electrochemical performance...
March 20, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38506506/pathway-toward-scalable-energy-efficient-li-mediated-ammonia-synthesis
#10
JOURNAL ARTICLE
Nishithan C Kani, Ishita Goyal, Joseph A Gauthier, Windom Shields, Mitchell Shields, Meenesh R Singh
Lithium-mediated ammonia synthesis (LiMAS) is an emerging electrochemical method for NH3 production, featuring a meticulous three-step process involving Li+ electrodeposition, Li nitridation, and Li3 N protolysis. The essence lies in the electrodeposition of Li+ , a critical phase demanding current oscillations to fortify the solid-electrolyte interface (SEI) and ensure voltage stability. This distinctive operational cadence orchestrates Li nitridation and Li3 N protolysis, profoundly influencing the NH3 selectivity...
March 20, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38503324/usefulness-and-description-of-the-intestinal-bypass-technique-in-children-with-short-bowel-syndrome-report-of-a-mexican-cohort
#11
JOURNAL ARTICLE
Eustorgio S García-Cárdenas, Isela Nuñez-Barrera, América L Miranda-Lora, Juan J Bolaños-Pérez, Rosalinda López-Rodríguez, Norma Briseño-Chavarria, Salvador Villalpando-Carrión
BACKGROUND: Short bowel syndrome (SBS) is one of the most frequent causes of intestinal failure, needing parenteral nutrition to maintain an energy-protein and water-electrolyte balance. At the Hospital Infantil de México Federico Gómez (HIMFG), the formation of two stomas is a technique used for intestinal rehabilitation, where the use of residue through the bypass technique (BT) helps to maintain gastrointestinal functionality, water-electrolyte, and nutritional stability...
2024: Boletín Médico del Hospital Infantil de México
https://read.qxmd.com/read/38503307/characterization-of-diclofenac-induced-renal-damage-in-normotensive-and-hypertensive-rats-a-comparative-analysis
#12
JOURNAL ARTICLE
Thaise Boeing, Alana Bittencourt F Lima, Maria Eduarda Busana, Luísa Nathália Bolda Mariano, Luisa Mota da Silva, Rita de Cássia Vilhena da Silva, Priscila de Souza
BACKGROUND: Diclofenac is the non-steroidal anti-inflammatory drug (NSAID) mostly prescribed worldwide, but it is highly associated with hypertension and acute kidney injury. Despite that, little information is available about the renal effects of diclofenac in hypertensive individuals, which led us to carry out this comparative study between the renal effects of this NSAID in normotensive (NTR) and spontaneously hypertensive rats (SHR). METHODS: Male Wistar NTR and SHR were orally treated with vehicle (V: 10 mL/kg) or diclofenac sodium (D: 100 mg/kg) once a day for 3 days...
March 19, 2024: Drug Research
https://read.qxmd.com/read/38497883/association-between-uncarboxylated-osteocalcin-blood-glucose-and-bmi-among-saudi-diabetic-patients-an-evaluation-study
#13
JOURNAL ARTICLE
T Alamri, F Alhumaydhi, A Z Wasti
OBJECTIVE: Uncarboxylated osteocalcin is an important osteocalcin enzyme found in the bloodstream and is a crucial protein for maintaining calcium binding in bones, controlling blood sugar levels, and balancing body minerals. PATIENTS AND METHODS: Due to the lack of data, the current study intends to investigate the relationship between uncarboxylated osteocalcin levels and DM-II in Saudi patients. For 138 patients, case-control research was conducted in 2021-2023, with 69 type II diabetes mellitus patients and 69 matching healthy control participants...
March 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38496848/-odd-skipped-related-2-as-a-novel-mark-for-labeling-the-proximal-convoluted-tubule-within-the-zebrafish-kidney
#14
JOURNAL ARTICLE
Wenmin Yang, Xiaoliang Liu, Zhongwei He, Yunfeng Zhang, Xiaoqin Tan, Chi Liu
The proximal convoluted tubule (PCT) of the kidney is a crucial functional segment responsible for reabsorption, secretion, and the maintenance of electrolyte and water balance within the renal tubule. However, there is a lack of a well-defined endogenous transgenic line for studying PCT morphogenesis. By analyzing single-cell transcriptome data from the adult zebrafish kidney, we have identified the expression of odd-skipped-related 2 ( osr2 , which encodes an odd-skipped zinc-finger transcription factor) in the PCT...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38496271/epoxy-based-multifunctional-solid-polymer-electrolytes-for-structural-batteries-and-supercapacitors-a-short-review
#15
REVIEW
Nitai Chandra Adak, Sungmook Lim, Guk-Hwan Lee, Wonoh Lee
The potential applications of epoxy-based solid polymer electrolytes are continually expanding because of their versatile characteristics. These characteristics include mechanical rigidity, nonvolatility, nonflammability, and electrochemical stability. However, it is worth noting that pure epoxy-based solid polymer electrolytes inherently exhibit lower ion transport capabilities when compared to traditional liquid electrolytes. Striking a balance between high mechanical integrity and superior ionic conductivity at room temperature poses a significant challenge...
2024: Frontiers in Chemistry
https://read.qxmd.com/read/38494585/research-progress-of-astragaloside-iv-in-treating-acute-kidney-injury
#16
REVIEW
Yu Liu, Youqun Huang, Dongxuan Sun, Naijing Ye, Tong Chen, Mengfan Yang, Li Zhou, Hequn Zou
Acute kidney injury (AKI) is one of the most common clinical critical illnesses, with decreased glomerular filtration rate, retention of nitrogen products, water and electrolyte disorders, and acid-base imbalance as the main clinical manifestations. Presently, there is no effective treatment for acute kidney injury, but the main treatment is to cure the primary disease, remove risk factors, maintain acid-base and water-electrolyte balance, and undergo kidney replacement. However, the mortality rate is still high...
March 18, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38489331/venous-blood-gases-and-electrolyte-values-of-captive-red-foot-tortoise-chelonoidis-carbonarius
#17
JOURNAL ARTICLE
Sofia Silva La Rocca de Freitas, Laís Velloso Garcia, Jairo Antonio Melo Dos Santos, Líria Queiroz Luz Hirano
Blood gas analysis reflects the exchange of oxygen and carbon dioxide in the lungs. This test provides important information, since the relationship between these gases has a direct impact on the acid-basic balance in the body. Given the significance of blood gas analysis in Brazilian reptiles, this study set out to establish temperature-corrected and uncorrected reference intervals for venous blood gas measurements in Chelonoidis carbonarius, and to compare values between females and males. In this study, 19 animals were used, 8 males and 11 females...
2024: PloS One
https://read.qxmd.com/read/38478606/regulate-transportation-of-ions-and-polysulfides-in-all-solid-state-li-s-batteries-using-ordered-mof-composite-solid-electrolyte
#18
JOURNAL ARTICLE
Jia Li, Fangxi Xie, Weiwei Pang, Qingyou Liang, Xianfeng Yang, Lei Zhang
A dilemma arises when striving to balance the maximum desired ion conductivity and minimize the undesired lithium polysulfide shuttling effect for all-solid-state lithium-sulfur batteries (ASSLSBs). Here, we introduce a strategy of using ordered MIL-125-NH2 as fillers for poly(ethylene oxide)-based electrolytes to simultaneously regulate the transportation of lithium ions and polysulfides. When compared to electrolytes lacking metal-organic frameworks (MOFs) and those containing disordered MOFs, the electrolyte featuring an ordered-MOF structure, denoted as three-dimensional (3D) MPPL composite solid electrolyte (CSE), exhibits the highest ion conductivity of 8...
March 15, 2024: Science Advances
https://read.qxmd.com/read/38477147/rational-lithium-salt-molecule-tuning-for-fast-charging-discharging-lithium-metal-battery
#19
JOURNAL ARTICLE
Pan Zhou, Haiyu Zhou, Yingchun Xia, Qingqing Feng, Xian Kong, Wenhui Hou, Yu Ou, Xuan Song, Hang-Yu Zhou, Weili Zhang, Yang Lu, Fengxiang Liu, Qingbin Cao, Hao Liu, Shuaishuai Yan, Kai Liu
The electrolytes for lithium metal batteries (LMBs) are plagued by a low Li+ transference number (T+) of conventional lithium salts and inability to form a stable solid electrolyte interphase (SEI). Here, we synthesized a self-folded lithium salt, lithium 2-[2-(2-methoxyethoxy)ethoxy]ethanesulfonyl(trifluoromethanesulfonyl) imide (LiETFSI), and comparatively studied with its structure analogue, lithium 1,1,1-trifluoro-N-[2-[2-(2-methoxyethoxy)ethoxy)]ethyl]methanesulfonamide (LiFEA). The special anion chemistry imparts the following new characteristics: i) In both LiFEA and LiETFSI, the ethylene oxide moiety efficiently captures Li+, resulting in a self-folded structure and high T+ around 0...
March 13, 2024: Angewandte Chemie
https://read.qxmd.com/read/38474100/lymphatic-system-and-the-kidney-from-lymphangiogenesis-to-renal-inflammation-and-fibrosis-development
#20
REVIEW
Elodie Stasi, Savino Sciascia, Carla Naretto, Simone Baldovino, Dario Roccatello
The lymphatic kidney system plays a crucial role in managing interstitial fluid removal, regulating fluid balance, and tuning immune response. It also assists in the reabsorption of proteins, electrolytes, cytokines, growth factors, and immune cells. Pathological conditions, including tissue damage, excessive interstitial fluid, high blood glucose levels, and inflammation, can initiate lymphangiogenesis-the formation of new lymphatic vessels. This process is associated with various kidney diseases, including polycystic kidney disease, hypertension, ultrafiltration challenges, and complications post-organ transplantation...
March 1, 2024: International Journal of Molecular Sciences
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