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https://www.readbyqxmd.com/read/29135812/optic-nerve-head-drusen-the-relationship-between-intraocular-pressure-and-optic-nerve-structure-and-function
#1
Kaitlyn W Nolan, Michael S Lee, Rohan A Jalalizadeh, Kevin C Firl, Gregory P Van Stavern, Collin M McClelland
OBJECTIVE: To determine whether at the time of diagnosis, the intraocular pressure (IOP) in patients with optic nerve head drusen (ONHD) correlates with the perimetric mean deviation (PMD) and the mean retinal nerve fiber layer (RNFL) thickness on optical coherence tomography (OCT). METHODS: This retrospective chart review included adults with ONHD from 2 academic medical centers. Inclusion criteria were age older than 18 years, definitive diagnosis of ONHD, measurement of IOP, and an automated visual field (VF) within 3 months of diagnosis...
November 9, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29128480/rapid-detection-of-haemophilus-parasuis-using-cross-priming-amplification-and-vertical-flow-visualization
#2
Hongchao Gou, Juan Li, Rujian Cai, Shuai Song, Miao Li, Dongxia Yang, Zhiyong Jiang, Yan Li, Pinpin Chu, Chunling Li
Haemophilus parasuis infection is of considerable economic importance in the swine industry due to high morbidity and mortality in naive swine populations. Accurate detection and identification of the causative agent are difficult, yet necessary, for disease control. In this study, a simple and rapid method of cross-priming amplification (CPA) with a vertical flow (VF) visualization strip was established to detect H. parasuis. The reaction can specifically identify 15 serovar reference strains and 57 clinically isolated strains of H...
November 9, 2017: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29123885/cardiac-arrest-caused-by-sibutramine-obtained-over-the-internet-a-case-of-a-young-woman-without-pre-existing-cardiovascular-disease-successfully-resuscitated-using-extracorporeal-membrane-oxygenation
#3
Naofumi Bunya, Keigo Sawamoto, Shuji Uemura, Ryoko Kyan, Hiroyuki Inoue, Junichi Nishida, Hidemichi Kouzu, Nobuaki Kokubu, Tetsuji Miura, Eichi Narimatsu
Case: Sibutramine is a weight loss agent that was withdrawn from the market in the USA and European Union because it increases adverse events in patients with cardiovascular diseases. However, non-prescription weight loss pills containing sibutramine can be still easily purchased over the Internet. A 21-year-old woman without history of cardiovascular diseases developed cardiac arrest. She was a user of a weight loss pills, containing sibutramine and hypokalemia-inducing agents, imported from Thailand over the Internet...
July 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29123868/cardiocerebral-and-cardiopulmonary-resuscitation-2017-update
#4
REVIEW
Gordon A Ewy
Sudden cardiac arrest is a major public health problem in the industrialized nations of the world. Yet, in spite of recurrent updates of the guidelines for cardiopulmonary resuscitation and emergency cardiac care, many areas have suboptimal survival rates. Cardiocerebral resuscitation, a non-guidelines approach to therapy of primary cardiac arrest based on our animal research, was instituted in Tucson (AZ, USA) in 2002 and subsequently adopted in other areas of the USA. Survival rates of patients with primary cardiac arrest and a shockable rhythm significantly improved wherever it was adopted...
July 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29123613/case-of-morphine-induced-ventricular-fibrillation
#5
Roman Skulec, Jitka Callerova, Jiri Knor, Petr Ostadal, Petr Kmonicek, Vladimir Cerny
No abstract text is available yet for this article.
2017: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29122647/an-automatic-system-for-the-comprehensive-retrospective-analysis-of-cardiac-rhythms-in-resuscitation-episodes
#6
Ali Bahrami Rad, Trygve Eftestøl, Unai Irusta, Jan Terje Kvaløy, Lars Wik, Jo Kramer-Johansen, Aggelos K Katsaggelos, Kjersti Engan
AIM: An automatic resuscitation rhythm annotator (ARA) would facilitate and enhance retrospective analysis of resuscitation data, contributing to a better understanding of the interplay between therapy and patient response. The objective of this study was to define, implement, and demonstrate an ARA architecture for complete resuscitation episodes, including chest compression pauses (CC-pauses) and chest compression intervals (CC-intervals). METHODS: We analyzed 126...
November 6, 2017: Resuscitation
https://www.readbyqxmd.com/read/29120655/-bone-quality-in-patients-with-acromegaly
#7
Martin Kužma, Ivana Ságová, Dušan Pavai, Peter Jackuliak, Zdenko Killinger, Peter Vaňuga, Juraj Payer
The impact of acromegaly on bone and the risk of fractures has not been sufficiently investigated. GH hypersecretion stimulates bone turnover, leading to an increase in bone turnover markers. Normal or even increased bone mineral density (BMD) in comparison to healthy controls have been reported, but there are some works where decreased BMD was observed among acromegaly patients with hypogonadism, particularly at lumbar spine. Less pronounced effect of GH overproduction was observed at the femoral neck, as explained by the positive effect of hypersecretion on the cortical bone (due to periosseal ossification)...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29118302/impact-of-the-relationship-between-the-defibrillation-threshold-dft-and-clinical-outcomes-in-recipients-of-modern-era-implantable-cardioverter-defibrillator-icd
#8
Yoshinari Enomoto, Mahito Noro, Masao Moroi, Masato Nakamura, Kaoru Sugi
Defibrillation threshold (DFT) testing during implantable cardioverter defibrillator (ICD) implantations is considered necessary for appropriate shock therapy and to measure the safety margin. However, the relationship between the DFT with modern era devices and the clinical outcome, including the total mortality is limited, which may lead to DFT testing itself being questioned. This study aimed to evaluate the relationship between the DFT and clinical outcome in ICD recipients.We enrolled 81 consecutive patients (66 males, aged 64...
November 8, 2017: International Heart Journal
https://www.readbyqxmd.com/read/29115388/antinociceptive-effect-of-valeriana-fauriei-regulates-bdnf-signaling-in-an-animal-model-of-fibromyalgia
#9
Hwayoung Lee, Jiyun Im, Hansol Won, Jun Young Kim, Hyung-Ki Kim, Jun-Tack Kwon, Young Ock Kim, Sanghyun Lee, Ik-Hyun Cho, Sang Won Lee, Hak-Jae Kim
The genus Valeriana has been widely used in popular medicine for centuries, to treat sleep disorders, anxiety, epilepsy and insomnia. Recent studies have focused on the novel pharmacological effects of Valeriana fauriei Briq. (VF) species. Previous studies have attempted to determine the pharmacological functions of Valeriana in various human diseases, particularly with regards to its neuroprotective effects, and its ability to reduce pain and stress. The present study constructed an animal model of fibromyalgia (FM), which was induced by intermittent cold stress with slight modification...
October 20, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29114888/cricothyroid-joint-type-as-predictor-for-vocal-fold-elongation-in-professional-singers
#10
Claudio Storck, Fabian Unteregger
OBJECTIVE: Vocal fold (VF) elongation vocal folds depends on two factors: the activity of the laryngeal muscles and the cricothyroid joint (CTJ). The aim of the study was to show the influence of the CTJ on VF elongation while singing a sustained vowel at different pitches. STUDY DESIGN: Prospective study. METHODS: Forty-nine female professional singers (25 sopranos, 24 altos) were recruited. Three-dimensional images of the larynx derived from high-resolution computed tomography scanning were obtained at the mean speaking fundamental frequency (F0) and one (F1) and two octaves (F2) above this pitch...
November 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29110492/observation-of-effective-pseudospin-scattering-in-zrsis
#11
Michael S Lodge, Guoqing Chang, Cheng Yi Huang, Bahadur Singh, Jack Hellerstedt, Mark T Edmonds, Dariusz Kaczorowski, Md Mofazzel Hosen, Madhab Neupane, Hsin Lin, Michael Fuhrer, Bent Weber, Masahiro Ishigami
3D Dirac semimetals are an emerging class of materials that possess topological electronic states with a Dirac dispersion in their bulk. In nodal-line Dirac semimetals, the conductance and valence bands connect along a closed path in momentum space, leading to the prediction of pseudospin vortex rings and pseudospin skyrmions. Here, we use Fourier transform scanning tunneling spectroscopy (FT-STS) at 4.5 K to resolve quasiparticle interference (QPI) patterns at single defect centers on the surface of the line nodal semimetal zirconium silicon sulfide (ZrSiS)...
November 7, 2017: Nano Letters
https://www.readbyqxmd.com/read/29110038/palytoxin-congeners
#12
REVIEW
Jiri Patocka, Eugenie Nepovimova, Qinghua Wu, Kamil Kuca
Palytoxin, isolated from a zoanthid of the genus Palythoa, is the most potent marine toxin known. Intoxication by palytoxin leads to vasoconstriction, hemorrhage, ataxia, muscle weakness, ventricular fibrillation, pulmonary hypertension, ischemia and death. Palytoxin and its numerous derivatives (congeners) may enter the food chain and accumulate mainly in fishes and crabs, causing severe human intoxication and death following ingestion of contaminated products. Furthermore, toxic effects in individuals exposed via inhalation or skin contact to marine aerosol in coincidence with Ostreopsis blooms, have been reported...
November 7, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/29107732/the-rapid-determination-of-bromadiolone-in-liver-and-blood-plasma-by-in-injector-pyrolysis-gas-chromatography-ion-trap-tandem-mass-spectrometry
#13
Veronika Doubková, Petr Maršálek, Vladimír Večerek
The unintentional poisoning of off-target animals by bromadiolone, a second generation anticoagulant rodenticide, is an undesirable outcome requiring sensitive analytical methods. In this study, a rapid and sensitive method for the determination of bromadiolone in liver and blood plasma by means of gas chromatography coupled with tandem mass spectrometry without need for derivatization was developed. The method is based on the in-injector pyrolysis of bromadiolone and subsequent gas chromatography coupled with ion trap tandem mass spectrometry with electron ionization...
October 14, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29106829/-sudden-cardiac-death-and-coronary-thrombus
#14
C Spaulding, N Karam
Out-of-hospital cardiac arrest is most often due to an acute coronary artery occlusion. The cause of coronary thrombosis in cardiac arrest is debated. Plaque erosion could be a trigger leading to immediate thrombus formation followed by ventricular fibrillation or rapid ventricular tachycardia. Coronary artery spasm is frequent: spasm provocation tests should be performed in survivors with normal coronary arteries. Use of drugs such as cocaine can lead to sudden death and blood sampling at arrival is recommended in survivors of out-of-hospital cardiac arrest...
October 26, 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29106375/genetic-and-neuronal-regulation-of-sleep-by-neuropeptide-vf
#15
Daniel A Lee, Andrey Andreev, Thai V Truong, Audrey Chen, Andrew J Hill, Grigorios Oikonomou, Uyen Pham, Young K Hong, Steven Tran, Laura Glass, Viveca Sapin, Jae Engle, Scott E Fraser, David A Prober
Sleep is an essential and phylogenetically conserved behavioral state, but it remains unclear to what extent genes identified in invertebrates also regulate vertebrate sleep. RFamide-related neuropeptides have been shown to promote invertebrate sleep, and here we report that the vertebrate hypothalamic RFamide neuropeptide VF (NPVF) regulates sleep in the zebrafish, a diurnal vertebrate. We found that NPVF signaling and npvf-expressing neurons are both necessary and sufficient to promote sleep, that mature peptides derived from the NPVF preproprotein promote sleep in a synergistic manner, and that stimulation of npvf-expressing neurons induces neuronal activity levels consistent with normal sleep...
November 6, 2017: ELife
https://www.readbyqxmd.com/read/29104685/the-use-of-computed-tomography-in-the-diagnosis-of-fatty-liver-and-abdominal-fat-distribution-among-a-saudi-population
#16
Gasim Ibrahim Gasim, Fahd Mohamed Elshehri, Mahmoud Kheidr, Fahad Khalid Alshubaily, ElZaki Mohamed ElZaki, Imad R Musa
BACKGROUND: The pandemic of obesity is striking heavily worldwide and particularly among the affluent Gulf States where it is expected to continue to rise along with its complications. AIM: To examine the link between liver fat infiltration and abdominal fat amount using plain computer-assisted tomography (CT). METHODS: Fifty patients visiting the obesity clinic of "King Fahd Specialist Hospital" or Dr Suliman Alhabeeb Hospital between January 2015 and April 2016 were included...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104199/-surgical-treatment-for-myocardial-rerupture-after-repair-of-post-infarction-left-ventricular-free-wall-rupture
#17
Chikashi Aoki, Kengo Tani, Ryou Taguchi, Ryousuke Kowatari, Norihiro Kondo, Masahito Minakawa, Ikuo Fukuda
A 73-year-old man was admitted for cardiac tamponade by oozing type left ventricular free wall rupture associated with acute myocardial infarction. Transthoracic echocardiography demonstrated moderate pericardial effusion and the presence of pseudoaneurysm within posterior wall. He went into shock with a systolic blood pressure of 60 mmHg. After introducing percutaneous cardiopulmonary support and intraaortic balloon pump, the sutureless repair was performed immediately. After having rehabilitation for right-sided hemiparesis, an elective pseudoaneurysm repair was planned...
November 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29103791/reversal-of-glaucoma-hemifield-test-results-and-visual-field-features-in-glaucoma
#18
Mengyu Wang, Louis R Pasquale, Lucy Q Shen, Michael V Boland, Sarah R Wellik, Carlos Gustavo De Moraes, Jonathan S Myers, Hui Wang, Neda Baniasadi, Dian Li, Rafaella Nascimento E Silva, Peter J Bex, Tobias Elze
PURPOSE: To develop a visual field (VF) feature model to predict the reversal of glaucoma hemifield test (GHT) results to within normal limits (WNL) after 2 consecutive outside normal limits (ONL) results. DESIGN: Retrospective cohort study. PARTICIPANTS: Visual fields of 44 503 eyes from 26 130 participants. METHODS: Eyes with 3 or more consecutive reliable VFs measured with the Humphrey Field Analyzer (Swedish interactive threshold algorithm standard 24-2) were included...
November 2, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29102980/real-time-ventricular-fibrillation-amplitude-spectral-area-analysis-to-guide-timing-of-shock-delivery-improves-defibrillation-efficacy-during-cardiopulmonary-resuscitation-in-swine
#19
Salvatore Aiello, Michelle Perez, Chad Cogan, Alvin Baetiong, Steven A Miller, Jeejabai Radhakrishnan, Christopher L Kaufman, Raúl J Gazmuri
BACKGROUND: The ventricular fibrillation amplitude spectral area (AMSA) predicts whether an electrical shock could terminate ventricular fibrillation and prompt return of spontaneous circulation. We hypothesized that AMSA can guide more precise timing for effective shock delivery during cardiopulmonary resuscitation. METHODS AND RESULTS: Three shock delivery protocols were compared in 12 pigs each after electrically induced ventricular fibrillation, with the duration of untreated ventricular fibrillation evenly stratified into 6, 9, and 12 minutes: AMSA-Driven (AD), guided by an AMSA algorithm; Guidelines-Driven (GD), according to cardiopulmonary resuscitation guidelines; and Guidelines-Driven/AMSA-Enabled (GDAE), as per GD but allowing earlier shocks upon exceeding an AMSA threshold...
November 4, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29102470/long-term-survival-trends-of-medicare-patients-after-in-hospital-cardiac-arrest-insights-from-get-with-the-guidelines-resuscitation-%C3%A2
#20
Lauren E Thompson, Paul S Chan, Fengming Tang, Brahmajee K Nallamothu, Saket Girotra, Sarah M Perman, Somnath Bose, Stacie L Daugherty, Steven M Bradley
BACKGROUND: Although rates of survival to hospital discharge after in-hospital cardiac arrest (IHCA) have improved over the last decade, it is unknown if these survival gains are sustained after hospital discharge. OBJECTIVE: To examine 1-year survival trends overall and by rhythm after IHCA. METHODS: Using Medicare beneficiaries (age≥65years) with IHCA occurring between 2000 and 2011 at Get With The Guidelines®-Resuscitation Registry participating hospitals we used multivariable regression, to examine temporal trends in risk-adjusted rates of 1-year survival...
November 1, 2017: Resuscitation
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