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https://www.readbyqxmd.com/read/29910747/korsakoff-syndrome-in-non-alcoholic-psychiatric-patients-variable-cognitive-presentation-and-impaired-frontotemporal-connectivity
#1
Georgios Nikolakaros, Timo Kurki, Janina Paju, Sokratis G Papageorgiou, Risto Vataja, Tuula Ilonen
Background: Non-alcoholic Wernicke's encephalopathy and Korsakoff syndrome are greatly underdiagnosed. There are very few reported cases of neuropsychologically documented non-alcoholic Korsakoff syndrome, and diffusion tensor imaging (DTI) data are scarce. Methods: We report clinical characteristics and neuropsychological as well as radiological findings from three psychiatric patients (one woman and two men) with a history of probable undiagnosed non-alcoholic Wernicke's encephalopathy and subsequent chronic memory problems...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29751937/beyond-thiamine-treatment-for-cognitive-impairment-in-korsakoff-s-syndrome
#2
REVIEW
Justin M Johnson, Valerie Fox
BACKGROUND: Wernicke's encephalopathy is a condition whose treatment many consultation-liaison psychiatrists know quite well. Less clear, however, is the treatment of its dementia disorder descendent, the Korsakoff's syndrome (KS). OBJECTIVE: This article seeks to review treatment options and provide recommendations for consultation-liaison psychiatrists treating cognitive impairment in KS. METHODS: In this nonsystematic review, we reviewed PubMed, CINAHL Plus, and Google Scholar for published reports and studies regarding treatment of KS...
March 27, 2018: Psychosomatics
https://www.readbyqxmd.com/read/29744060/what-can-go-wrong-in-hyperemesis-gravidarum-wernicke-korsakoff-syndrome-in-bulawayo-zimbabwe
#3
Fiona T Nhari, Narcisious B T Dzvanga
We report two cases of Wernicke-Korsakoff syndrome (WKS) secondary to hyperemesis gravidarum. Oral thiamine was administered (intravenous unavailable locally). However, both the patient's condition improved in the first 48 h and progressively over a month. Initially, WKS is missed due to rare feature of full classical triad of symptoms, especially in nonalcoholics.
May 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29714153/thiamine-and-alcohol-for-brain-pathology-super-imposing-or-different-causative-factors-for-brain-damage
#4
Rita Moretti, Paola Caruso, Matteo Dal Ben, Silvia Gazzin, Claudio Tiribelli
Drinking more than the recommended limits is a worldwide emerging problem, difficult to circumscribe, and alcohol related brain damages are an under-recognized health problem. Alcohol-cognitive disruption can be considered as transient and recoverable if the alcohol consumption is limited and occasional; if not, it can progress to the so-called alcohol-related dementia (ARD), or to the Wernicke encephalopathy, or it can even induce the Korsakoff syndrome, an irreversible and long-lasting medical condition. ARD still remains poorly diagnosed and addressed, even if it had recently raised increased research interest...
April 2, 2018: Current Drug Abuse Reviews
https://www.readbyqxmd.com/read/29694308/severe-neurological-complication-following-adjustable-gastric-banding
#5
G Martines, N Musa, F Aquilino, P Capuano
AIM: In the last years with the increase of bariatric surgery, first of all as a result of new indications, a rise in the incidence of nutrient-related complications has been observed. Currently little is known about the impact of post-bariatric malnutrition and neurological complications. Wernicke's encephalopathy is a severe neurological syndrome which occurs as a result of thiamine deficiency. Wernicke-Korsakoff syndrome must be considered a serious neurological complication of bariatric surgery with significant morbidity and mortality, with rapidly progressing neurological symptoms, and must be treated immediately...
March 2018: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29680910/forgetting-the-new-locations-of-one-s-keys-spatial-memory-interference-in-korsakoff-s-amnesia
#6
Albert Postma, Sascha G Morel, Margot E Slot, Erik Oudman, Roy P C Kessels
The present study focused on interference in a group of patients with amnesia due to Korsakoff's syndrome (KS) within the domain of spatial memory. An object-location memory task was used in which participants first learned an array of objects on a computer screen, followed by a reconstruction of the object positions. Next a trial was given in which the same objects were presented only now in different locations. Participants had to place the objects a second time but at the new locations. This was repeated for seven pairs of baseline/interference trials...
April 21, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29679843/impaired-affective-prosody-decoding-in-severe-alcohol-use-disorder-and-korsakoff-syndrome
#7
Mélanie Brion, Philippe de Timary, Serge Mertens de Wilmars, Pierre Maurage
Recognizing others' emotions is a fundamental social skill, widely impaired in psychiatric populations. These emotional dysfunctions are involved in the development and maintenance of alcohol-related disorders, but their differential intensity across emotions and their modifications during disease evolution remain underexplored. Affective prosody decoding was assessed through a vocalization task using six emotions, among 17 patients with severe alcohol use disorder, 16 Korsakoff syndrome patients (diagnosed following DSM-V criteria) and 19 controls...
June 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29658505/-the-possibilities-of-neurostimulation-sympathetic-correction-in-the-treatment-of-amnestic-korsakoff-s-psychosis
#8
A V Fedotovskih, K Yu Retyunskiy, T S Petrenko, V S Kublanov
AIM: To evaluate the efficacy of non-invasive multichannel electrical stimulation (sympathetic correction) in patients with alcohol amnesic (Korsakoff's) psychosis. MATERIAL AND METHODS: Thirty-seven men, aged 33-48 years, with Korsakoff's (amnestic) psychosis were studied. The duration of disease varied from 12 to 24 month. The device of electrical stimulation of neck nerve structures was used for neuroelectrostimulation. Treatment included 15 sessions within 3 weeks...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29509075/imbalance-between-cognitive-systems-in-alcohol-dependence-and-korsakoff-syndrome-an-exploration-using-the-alcohol-flanker-task
#9
Mélanie Brion, Valérie Dormal, Séverine Lannoy, Serge Mertens, Philippe de Timary, Pierre Maurage
BACKGROUND: Alcohol-dependent individuals (ALC) simultaneously present decreased inhibitory control and increased attention towards alcohol-related cues. The dual-process models have proposed that these symptoms reflect an imbalance between prefrontal/reflective and limbic/automatic systems, respectively leading to cognitive dysfunctions in executive processes and to alcohol-related bias. However, most previous research has focused on a separate exploration of these systems among ALC, and the direct measure of their interactions remains to be conducted...
March 6, 2018: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/29501971/seeing-life-through-rose-colored-spectacles-autobiographical-memory-as-experienced-in-korsakoff-s-syndrome
#10
Mohamad El Haj, Jean Louis Nandrino
We investigated whether patients with Korsakjoff's Sybdrome (KS) would demonstrate a discrepancy between (low) autobiographical specificity and (high) sense of reliving. We invited 20 KS patients and 24 controls to retrieve personal memories. After memory retrieval, they were invited to rate subjective characteristics of their recall (e.g., reliving, travel in time, remembering, realness). Besides this rating, we analyzed memories objectively with regard to specificity. Analysis demonstrated poorer sense of reliving and memory specificity in KS patients than in controls...
April 2018: Consciousness and Cognition
https://www.readbyqxmd.com/read/29411941/preserved-re-experience-of-discrete-emotions-amnesia-and-executive-function
#11
Marian Andrei Stanciu, Robert D Rafal, Oliver H Turnbull
Amnesic patients can re-experience emotions elicited by forgotten events, suggesting that brain systems for episodic and emotional memory are independent. However, the range of such emotional memories remains under-investigated (most studies employing just positive-negative emotion dyads), and executive function may also play a role in the re-experience of emotions. This is the first investigation of the intensity of the emotional re-experience of a range of discrete emotions (anger, fear, sadness, and happiness) for a group of amnesic patients...
February 7, 2018: Journal of Neuropsychology
https://www.readbyqxmd.com/read/29400641/diagnosis-makes-a-difference-perceptions-of-older-persons-with-dementia-symptoms
#12
Jed A Diekfuss, Jessica De Larwelle, Susan H McFadden
Background/Study Context: Employing the stereotype content model and terror management theory, we examined whether stereotypes and feelings about persons with dementia vary depending on the type of dementia diagnosis and purported causes of the dementia. METHODS: Participants were randomly assigned to read one of four vignettes that depicted a man who consulted his doctor because of memory problems. All vignettes described the same symptoms and diagnostic tests, but each of four groups read a different result: all tests normal (Normal); Alzheimer's disease (AD); Wernicke-Korsakoff Syndrome (WKS) associated with alcohol abuse; and chronic traumatic encephalopathy (CTE) associated with head injuries from playing football in high school and college...
March 2018: Experimental Aging Research
https://www.readbyqxmd.com/read/29380664/wernicke-korsakoff-syndrome-as-a-rare-phenotype-of-sporadic-creutzfeldt-jakob-disease
#13
Joanna Bielewicz, Anna Szczepańska-Szerej, Magdalena Ogórek, Piotr Dropko, Katarzyna Wojtal, Konrad Rejdak
We reported the case of a patient with Wernicke-Korsakoff syndrome (WKs) as an early clinical manifestation of sporadic Creutzfeld-Jakob disease (sCJD). The 66-year-old female complained of dizziness and imbalance which mostly occurred while walking. A neurological examination revealed a triad of symptoms characteristic for WKs such as gaze paresis, ataxia of limbs and trunk as well as memory disturbances with confabulations. The disturbances increased during the course of the disease, which led to the death of the patient four months after the appearance of the signs...
February 9, 2018: Prion
https://www.readbyqxmd.com/read/29373764/-wernicke-korsakoff-syndrome-secondary-to-cytomegalovirus-encephalitis-a-case-report
#14
Luis Guillermo Uribe, María Alejandra Pérez, Camilo Andrés Lara, Natalia Rueda, Javier Augusto Hernández
Cytomegalovirus (CMV) is one of the opportunistic microorganisms with the highest prevalence in immunocompromised patients. Reactivation has decreased after the introduction of highly active antiretroviral therapy (HAART). Encephalitis has been reported in the coinfection as one of the most frequent presentations.We present the case of a young adult patient with HIV infection and rapid neurological deterioration due to classic clinical symptoms and signs of the Wernicke-Korsakoff syndrome, with no risk factors for thiamine deficiency, with images by nuclear magnetic resonance typical of the syndrome, and identification of cytomegalovirus in cerebrospinal fluid...
December 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29283625/the-implicit-revolution-reconceiving-the-relation-between-conscious-and-unconscious
#15
Anthony G Greenwald, Mahzarin R Banaji
In the 1970s, memory researchers converged on interesting phenomena observed in Korsakoff-syndrome amnesic patients. These patients' performances on difficult tasks were reliably improved by practice sessions from which they could recall nothing. Related findings of indirect memory effects in college students triggered wide attention to phenomena that, in 1985, were first identified as implicit memory. Within a decade, the indirect measurement methods of implicit memory research had spread to social psychologists' studies of attitudes and stereotypes...
December 2017: American Psychologist
https://www.readbyqxmd.com/read/29225466/korsakoff-s-syndrome-a-critical-review
#16
REVIEW
Nicolaas Jm Arts, Serge Jw Walvoort, Roy Pc Kessels
In this review, we present a survey on Korsakoff's syndrome (KS), a residual syndrome in patients who suffered from a Wernicke encephalopathy (WE) that is predominantly characterized by global amnesia, and in more severe cases also by cognitive and behavioral dysfunction. We describe the history of KS and its definition, its epidemiology, and the lack of consensus criteria for its diagnosis. The cognitive and behavioral symptoms of KS, which include anterograde and retrograde amnesia, executive dysfunction, confabulation, apathy, as well as affective and social-cognitive impairments, are discussed...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29225465/the-effect-of-errorless-learning-on-quality-of-life-in-patients-with-korsakoff-s-syndrome
#17
Yvonne Cm Rensen, Jos Im Egger, Josette Westhoff, Serge Jw Walvoort, Roy Pc Kessels
Background: Errorless learning (EL) is a promising rehabilitation principle for (re)learning instrumental activities in patients with amnesia, including patients with Korsakoff's syndrome (KS). Successfully (re)learning tasks might improve the sense of competence and independence, and subsequently the quality of life. Quality of life in patients with KS has received limited attention, and no studies have been conducted to experimentally examine the effect of EL on quality of life in patients in this patient group...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29188542/wet-beriberi-associated-with-hikikomori-syndrome
#18
Natsumi Tanabe, Eiji Hiraoka, Jun Kataoka, Takaki Naito, Ko Matsumoto, Junya Arai, Yasuhiro Norisue
Wet beriberi, characterized by high cardiac output with predominantly right-sided heart failure and lactic acidosis, is a disease caused by thiamine deficiency, and is rarely seen in modern society. However, patients with social withdrawal syndrome, also known as hikikomori syndrome, may be a new population at risk of thiamine deficiency. Hikikomori syndrome, first recognized in Japan, is becoming a worldwide issue. A 39-year-old Japanese patient was brought to our hospital, with a 3-week history of progressive shortness of breath and generalized edema...
March 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29128903/impairment-of-thiamine-transport-at-the-gut-bbb-axis-contributes-to-wernicke-s-encephalopathy
#19
P M Abdul-Muneer, Saleena Alikunju, Heather Schuetz, Adam M Szlachetka, Xiaotang Ma, James Haorah
Wernicke's encephalopathy, a common neurological disease, is caused by thiamine (vitamin B1) deficiency. Neuropathy resulting from thiamine deficiency is a hallmark of Wernicke-Korsakoff syndrome in chronic alcohol users. The underlying mechanisms of this deficiency and progression of neuropathy remain to be understood. To uncover the unknown mechanisms of thiamine deficiency in alcohol abuse, we used chronic alcohol consumption or thiamine deficiency diet ingestion in animal models. Observations from animal models were validated in primary human neuronal culture for neurodegenerative process...
November 11, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/29128624/wernicke-korsakoff-syndrome-complicated-by-subacute-beriberi-neuropathy-in-an-alcoholic-patient
#20
Salvatore Di Marco, Laura Pilati, Filippo Brighina, Brigida Fierro, Giuseppe Cosentino
Thiamine (vitamin B1) deficiency is a common condition in alcohol abusers, which can lead to damage of both the peripheral and the central nervous systems. Here we describe the case of an alcoholic patient who presented with acute onset of ataxia, severe weakness of the four limbs, and hypoesthesia and dysesthesia of the distal portion of the upper and lower extremities. The clinical picture also included mental confusion and amnesia. A diagnosis of Wernicke-Korsakoff syndrome was made based on clinical symptoms and brain RMI findings...
January 2018: Clinical Neurology and Neurosurgery
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