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renal replacement and hémodialyse

Zhi-Hao Zhang, Jia-Rong Mao, Hua Chen, Wei Su, Yuan Zhang, Li Zhang, Dan-Qian Chen, Ying-Yong Zhao, Nosratola D Vaziri
BACKGROUND: Although dialysis ameliorates uremia and fluid and electrolytes disorders, annual mortality rate remains high in dialysis population reflecting its shortcoming in replacing renal function. Unlike the normal kidney, dialysis causes dramatic shifts in volume and composition of body fluids and indiscriminate removal of vital solutes. Present study was undertaken to determine the impact of hemodialysis on plasma metabolites in end-stage renal disease (ESRD) patients. METHODS: 80 hemodialysis patients and 80 age/gender-matched healthy controls were enrolled in the study...
December 2017: Clinical Biochemistry
Hermine Fouda, Gloria Ashuntantang, François Kaze, Marie-Patrice Halle
INTRODUCTION: Haemodialysis is the only renal replacement therapy available in Cameroon; 95% of patients has received subsidies by the State since 2002 and the number of dialysis centers is growing. However, since the opening of the first center in 1990, there are no data on survival in chronic dialysis patients. METHODS: We conducted a multicenter prospective cohort study of 15 months in order to assess mortality rates and factors that influence the survival of chronic hemodialysis patients in Cameroon...
2017: Pan African Medical Journal
C Voiculeț, O Zara, I Văcăroiu, C Bogeanu, T Tiron, F Turcu, G Aron, A Ciocâlteu
Introduction. Arterial stiffness and vascular calcifications are independent predictors of cardiovascular morbidity and mortality in the chronic kidney disease (CKD) stage 5D population. According to the guidelines, patients on renal replacement therapy represent a very high cardiovascular risk class. Case report. We report the case of a 67-year-old hypertensive male patient, known with CKD stage 5D on hemodialysis (three times per week), secondary bone mineral disease, admitted for progressive right leg pain...
October 2016: Journal of Medicine and Life
Joanna Stępniewska, Barbara Dołęgowska, Marta Chruściana, Edyta Gołembiewska, Alicja Malinowska-Jędraszczyk, Małgorzata Marchelek-Myśliwiec, Kazimierz Ciechanowski
INTRODUCTION: CD154 is a surface glycoprotein present on activated platelets, lymphocytes and mast cells. It mediates the transmission of information between cells and initiates an inflammatory response. The interaction of CD154 with its receptor CD40 leads to increase in concentrations of soluble forms of both molecules (sCD154, sCD40), which has an important prognostic value in cardiovascular complications. The metabolic disorders in chronic kidney disease (CKD), chronic inflammation, increased oxidative stress and type of renal replacement therapy may influence on the balance of sCD154/sCD40 in plasma and blood platelets...
February 2016: Clinical Biochemistry
Katarzyna Krystyna Snarska, Katarzyna Sejnota, Hanna Bachórzewska-Gajewska, Jolanta Małyszko
Acute respiratory distress together with hypoxia could be an indication for admission to intensive care unit. It may also lead to acute kidney injury. In addition, mechanical ventilation may be an additional factor for development of acute kidney injury. The aim of the work was to assess the prevalence of acute kidney injury, including the need for renal replacement therapy in patients with acute respiratory distress treated in intensive care unit. In addition, the effect of acute kidney injury on outcome of patients with acute respiratory distress was evaluated...
2014: Przegla̧d Lekarski
Christian von Heymann, Lutz Kaufner, Mareike Körber
The new oral anticoagulants directly inhibit either thrombin (Dabigatran, Pradaxa®,) or activated Factor X (rivaroxaban, Xarelto®, and apixaban, Eliquis®) and have been approved for thromboprophylaxis after hip and knee replacement surgery and stroke prevention in non-valvular atrial fibrillation. Moreover, rivaroxaban has been approved for the treatment of deep venous thrombosis, prevention of pulmonary embolism and anticoagulation after acute myocardial infarction. The direct FXa-inhibitor edoxaban (Lixiana®) expects approval for the prevention of stroke in atrial fibrillation in Germany in 2014...
March 2014: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
László Kovács, Eva Virágh, Dóra Balogh, Bernadette Kálmán, Zoltán Lőcsei, Erzsébet Toldy
INTRODUCTION: Parathyroid hormone levels provide important information in chronic renal failure. AIM: To compare parathyroid hormone levels measured by two assays in correlation with vitamin D supply. METHOD: Parathyroid hormone and 25-hydroxi-vitamin-D were determined in 104 patients (31 patients with chronic renal failure without renal replacement therapy, 36 patients treated with peritoneal dialysis and 37 patients treated with hemodialysis)...
December 22, 2013: Orvosi Hetilap
(no author information available yet)
OBJECTIVE: To investigate the renal replacement therapy and outcome of chronic renal failure (CRF) in childhood, a nation-wide survey was conducted and data of hospitalized children (younger than 18 years old) with CRF during the period of 2007 to 2011 were analyzed. METHOD: Questionnaires of renal replacement therapy of patients with CRF in childhood were designed and distributed to 28 hospitals in China. The data were collected and analyzed. RESULT: There were 1033 hospitalized children with CRF from January 1, 2007 to December 31, 2011 in 28 hospitals...
July 2013: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
Bolesław Rutkowski, Ryszard Nowaczyk, Przemysław Rutkowski, Piotr Mierzicki
Healthcare development is the fact in the present world. Because of this the improvement of the quality of care and life of patients is of great importance. Since six years in our country, the study concerning quality of life and care of hemodialysed patients (QC vs QL) is performed annually. In three subsequent papers results of studies performed between 2006 and 2009 are summarised. Almost 7000 patients were studies in the analysed period. This was more than 10% of dialysed patients in every year. In the present paper we focused on the hemodialysis modalities and concomitant therapy...
2011: Przegla̧d Lekarski
Marta Makara-Studzińska, Piotr Ksiazek, Anna Koślak, Wojciech Załuska, Andrzej Ksiazek
AIM: The depressive symptoms are common in patients with end-stage kidney disease but they are often undiagnosed and can complicate the renal replacement therapy. The aim of this study was to identify significant differences in frequency and severity of depressive symptoms among patients with end-stage renal disease depending on what form of treatment they are undergoing--hemodialysis, peritoneal dialysis and patients after kidney transplantation. METHODS: 323 patients with end-stage renal failure were examined...
March 2011: Psychiatria Polska
Julie Calixto Lobo, Denise Mafra, Najla Elias Farage, Tanize do Espirito Santo Faulin, Dulcineia Saes Parra Abdalla, Antonio Claudio Lucas de Nóbrega, João Paulo Machado Torres
BACKGROUND: Chronic Kidney Disease (CKD) patients present high levels of electronegative LDL (LDL-) that can modulate the expression of molecules involved in inflammation and it is closely linked to atherosclerosis. We investigated the association between LDL(-) and inflammatory markers in patients undergoing hemodialysis (HD). METHODS: Forty-seven HD patients from a private clinic in Rio de Janeiro, Brazil were studied and compared with 20 age matched healthy individuals...
September 18, 2011: Clinica Chimica Acta; International Journal of Clinical Chemistry
Tokuhiro Kimura, Masayoshi Komura, Yasuhiro Okubo
Giant cell arteritis involving intramural coronary artery branches is rare, and its clinical features remain poorly understood. We report a 56-year-old hemodialysed patient with a history of mitral valve replacement, who presented with "fever of unknown origin" and intractable hypotension. The antemortem diagnosis was very difficult and the autopsy revealed giant-cell-rich vasculitis in arteries in multiple organs. The heart was most severely involved, in which almost all of the intramural coronary artery branches were infiltrated by many multinucleated giant cells, macrophages, and lymphocytes with luminal narrowing, but the epicardial segments of the coronary arteries were spared...
March 2012: Heart and Vessels
Xin Qi, Yinan Zhang, Jiayuan Gao, Tianlu Chen, Aihua Zhao, Yucheng Yan, Wei Jia
Hemodialysis is an important alternative for renal replacement therapy to remove uremic retention solutes (URS) for the uremic syndrome. The metabolites in the hemodialysate directly reflect the efficiency of URS clearance. Here we report a highly sensitive and reliable metabolomic procedure for the measurement of small molecule metabolites in hemodialysate using gas chromatography coupled with time-of-flight mass spectrometry (GC/TOF/MS). The method was developed and evaluated through orthogonal experimental design using multivariate statistical analysis...
July 15, 2011: Journal of Pharmaceutical and Biomedical Analysis
Naoko Nakaigawa, Ryu Komatsu, Kotoe Kamata, Makoto Ozaki
We experienced anesthesia of a patient with pheochromocytoma on chronic hemodialysis who developed severe hypotension resistant to vasopressors after induction of general anesthesia. She was presented for spine surgery for destructive arthropathy of the cervical spine. Doxazosin up to 0.5 mg x day(-1) was administered for five days preoperatively for alpha-adrenergic blokade and regular hemodialysis was continued until the day before surgery without change in dry body weight. Blood pressure (BP) was within normal limits preoperatively...
June 2010: Masui. the Japanese Journal of Anesthesiology
I A Checheriţă, Flavia Turcu, R F Dragomirescu, A Ciocâlteu
Although hemodialysis technique has improved in the last decades and the accessibility to this life-sustaining treatment modality increased rapidly, we are still concerned about the morbidity and mortality rates of dialysis patients. While technical advances are increasing the efficacy and safety of renal replacement therapies, latest studies are focused on other outcomes: increasing survival rates and the quality of life by an adequate management of the complications in chronic renal patients. This article reviews the complications of chronic hemodialysed patient with special considerations for the role of the primary renal disease that caused renal failure...
2010: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
Jolanta Malyszko, Jacek S Malyszko, Piotr Kozminski, Michal Mysliwiec
UNLABELLED: Hepcidin is a small defensin-like peptide, the production of which by hepatocytes is modulated in response to anemia, hypoxia, or inflammation. Kidneys are involved in not only the synthesis of hepcidin, but they also may be involved in its elimination. A cross-sectional study was performed to assess prohepcidin and hepcidin in serum, urine, and ultrafiltrate/peritoneal effluent in relation to type of renal replacement therapy and prohepcidin and hepcidin correlations with renal function, iron status, and markers of inflammation...
2009: Renal Failure
Dominika Adamczuk, Helena Ziołkowska, Beata Leszczyńska, Maria Roszkowska-Blaim
The authors present a 14-year old boy with acute renal failure in the course of hemolytic-uremic syndrome (HUS), preceded by bloody diarrhea of unknown origin. The course of HUS was complicated with hypertensive crisis, pleural effusion. Pleural puncture was complicated with massive hemorrhage which required thoracotomy. Additional risk factor were subendocardial perfusion disorders found in MRI scan of the heart and peripheral peroneal nerve palsy (in neuro-motorical conduction examination--severe neuropathy)...
April 2009: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Dorota Polak-Jonkisz, Krystyna Laszki-Szczachor, Danuta Zwolińska, Lesław Rusiecki, Maria Miler, Małgorzata Sobieszczańska
UNLABELLED: The highest percent of cardiac muscle damages is written down in children which are exposed to hemodialysis. In this group the heart examinations using body surface heart potential mapping (BSPM) method have been carried out. The aim of the study was to assess the influence of hemodialysis on heart's electrodynamics in children and adolescent during replacement therapy. MATERIAL AND METHODS: Multielectrode recording have been done in every kid before and after hemodialysis...
April 2009: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Jan Blacha, Robert Kolodziej, Marek Karwanski
BACKGROUND AND PURPOSE: Femoral neck fractures are considerably more common in patients on hemodialysis than in the general population. We determined the outcome of bipolar hemiarthroplasty for hip fracture in patients with long-term hemodialysis and compared it with that of a matched-paired group of patients with intact renal function. METHODS: We analyzed 26 bipolar hemiarthroplasties in 23 hemodialysed patients with a mean age of 56 (41-78) years who were followed for mean 3...
April 2009: Acta Orthopaedica
George Chrysochoou, R J Marcus, K K Sureshkumar, R L McGill, Brian W Carlin
Acute renal failure is common in critically ill patients. Many intensive care unit patients require renal replacement therapy (RRT). Hemodialysis can be performed as intermittent treatments or as continuous RRT, which can be customized to clinical goals by the use of carefully designed replacement fluids and hemodialysates. The available forms of RRT are reviewed, with emphasis on the clinical indications that contribute to the choice and design of therapy. Practical issues and troubleshooting are discussed, as are available options for anticoagulation during RRT...
October 2008: Critical Care Nursing Quarterly
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