keyword
https://read.qxmd.com/read/38647724/efficacy-of-electroacupuncture-therapy-in-patients-with-functional-anorectal-pain-study-protocol-for-a-multicenter-randomized-controlled-trial
#1
JOURNAL ARTICLE
Yahong Xue, Huifen Zhou, Yusha Zeng, Chen Wang, Yun Yang, Xiaopeng Wang, Zongqi He, Yibo Yao, Xiaofeng Wang, Zhimin Fan
BACKGROUND: Some Chinese scholars have initially explored the efficacy of electroacupuncture at Baliao acupoint in patients with functional anorectal pain (FAP). However, their studies are performed in a single center, or the sample size is small. Therefore, we aim to further explore the efficacy of electroacupuncture at Baliao acupoint on the treatment of FAP. METHODS: In this multicenter randomized controlled trial, 136 eligible FAP patients will be randomly allocated into an electroacupuncture group or sham electroacupuncture group at a 1:1 ratio...
April 22, 2024: International Journal of Colorectal Disease
https://read.qxmd.com/read/38647694/a-qualitative-evaluation-of-the-oncologists-neurologists-and-pain-specialists-views-on-the-management-and-care-of-chemotherapy-induced-peripheral-neuropathy-in-the-netherlands
#2
JOURNAL ARTICLE
F G A M van Haren, M A H Steegers, K C P Vissers, S A S van den Heuvel
PURPOSE: In treating cancer, different chemotherapy regimens cause chemotherapy-induced peripheral neuropathy (CIPN). Despite recent international guidelines, a gold standard for diagnosis, treatment, and care is lacking. To identify the current clinical practice and the physicians' point of view and ideas for improvement, we evaluated CIPN care by interviewing different specialists involved. METHODS: We performed semi-structured, audio-recorded, transcribed, and coded interviews with a purposive sample of oncologists, pain specialists, and neurologists involved in CIPN patients' care...
April 22, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38646388/comparative-efficacy-of-non-invasive-therapies-in-temporomandibular-joint-dysfunction-a-systematic-review
#3
REVIEW
Hesham A Alowaimer, Sultan S Al Shutwi, Mohammed K Alsaegh, Ohood M Alruwaili, Abdullah R Alrashed, Salwa H AlQahtani, Mohammed S Batais
Temporomandibular disorder (TMD) is a multifaceted disorder impacting the temporomandibular joint (TMJ), causing substantial discomfort and functional limitations. This systematic review aims to comprehensively assess the effectiveness of non-invasive treatment modalities for TMJ dysfunction, prioritizing a definitive protocol to ensure patient safety and enhance quality of life. Employing the PRISMA guidelines, we meticulously analyzed 20 studies from a pool of 1,417 articles sourced from databases such as PubMed, Google Scholar, ScienceDirect, and Medline...
March 2024: Curēus
https://read.qxmd.com/read/38645760/selected-morphological-cardiovascular-and-neuromuscular-risk-profiles-among-asymptomatic-sedentary-men-performing-islamic-prayer
#4
JOURNAL ARTICLE
Abdul Hamid Jalal, Habib Noorbhai
BACKGROUND: This study investigated morphological, cardiovascular and neuromuscular profiles among asymptomatic sedentary men performing the Islamic prayer (Salaah). This study emphasised the need for an inquiry into unique sedentary populations who perform Islamic prayer as physical activity. METHODS: An experimental study was conducted among male participants (n=20). Resting heart rate (RHR), resting systolic blood pressure (SBP), resting diastolic blood pressure (DBP), body mass index (BMI) and percentage body fat (BF%) were measured before a timed Salaah simulation activity...
2024: BMJ Open Sport & Exercise Medicine
https://read.qxmd.com/read/38645694/an-8-month-adapted-motor-activity-program-in-a-young-cmt1a-male-patient
#5
JOURNAL ARTICLE
Giorgio Bottoni, Oscar Crisafulli, Caterina Pisegna, Marco Serra, Sara Brambilla, Fausto Feletti, Giovanni Cremonte, Giuseppe D'Antona
BACKGROUND: It is unclear whether prolonged periods of training can be well tolerated. In Charcot-Marie Tooth disease (CMT). We report the effects of an 8-month, adapted motor activity (AMA) program in a 16-years-old CMT1A male patient. The program included strength, mobility, and balance training (two sessions per week, 1 h per session). MEASURES: Walking ability and walking velocity (Six-Minute Walking Test-6MWT, Ten Meters Walking Test-10 mW T), balance (Y-Balance Test-YBT, Berg Balance Scale-BBS), functional mobility (Short Physical Performance Battery-Short physical performance battery), fatigue (Checklist Individual strength questionnaire - CIS20R), health and quality of life (Short Form Health Survey 36 questionnaire-SF-36) were evaluated in three moments: before (T0), after 5 (T1) and 8 (T2) months of adapted motor activity...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38644209/-a-pedigree-of-myotonia-congenita-with-a-novel-mutation-p-f343c-of-the-clcn1-gene
#6
JOURNAL ARTICLE
Yoshitsugu Nakamura, Hidenori Sato, Kensuke Kakiuchi, Yuki Miyano, Takafumi Hosokawa, Shigeki Arawaka
A Japanese woman experienced slowness of movement in her early teens and difficulty in opening her hands during pregnancy. On admission to our hospital at 42 years of age, she showed grip myotonia with warm-up phenomenon. However, she had neither muscle weakness, muscle atrophy, cold-induced symptomatic worsening nor episodes of transient weakness of the extremities. Needle electromyography of the first dorsal interosseous and anterior tibial muscles demonstrated myotonic discharges. Whole exome sequencing of the patient revealed a heterozygous single-base substitution in the CLCN1 gene (c...
April 20, 2024: Rinshō Shinkeigaku, Clinical Neurology
https://read.qxmd.com/read/38644066/recovery-of-spatio-temporal-gait-and-functional-parameters-following-unilateral-eccentric-exercise-induced-muscle-damage-in-the-hamstrings
#7
JOURNAL ARTICLE
Pablo Bellosta-López, Rafael Giner-Nicolás, Alejandro Molina-Molina, Alberto Rubio-Peirotén, Luis Enrique Roche-Seruendo, Víctor Doménech-García
OBJECTIVES: This study aimed to analyze how spatiotemporal gait parameters, active knee extension range of motion, muscle activity, and self-perceived function change over a seven-day period in healthy individuals after exercise-induced muscle damage (EIMD) in the hamstrings. DESIGN: Longitudinal cohort study. METHODS: Twenty-four healthy males participated in four sessions before and after EIMD (pre-EIMD, 48 h, 96 h, and 168 h post-EIMD)...
April 6, 2024: Journal of Science and Medicine in Sport
https://read.qxmd.com/read/38643884/assessing-intracellular-and-extracellular-distribution-of-antibiotic-resistance-genes-in-the-commercial-organic-fertilizers
#8
JOURNAL ARTICLE
Wei Liu, Wan-Ying Xie, Hong-Jun Liu, Chuan Chen, Shu-Yao Chen, Gao-Fei Jiang, Fang-Jie Zhao
Compost-based organic fertilizers often contain high levels of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs). Previous studies focused on quantification of total ARGs and MGEs. For a more accurate risk assessment of the dissemination risk of antibiotic resistance, it is necessary to quantify the intracellular and extracellular distribution of ARGs and MGEs. In the present study, extracellular ARGs and MGEs (eARGs and eMGEs) and intracellular ARGs and MGEs (iARGs and iMGEs) were separately analyzed in 51 commercial composts derived from different raw materials by quantitative polymerase chain reaction (qPCR) and metagenomic sequencing...
April 19, 2024: Science of the Total Environment
https://read.qxmd.com/read/38642898/neural-hyperresponsivity-during-the-anticipation-of-tangible-social-and-non-social-rewards-in-autism-spectrum-disorder-a-concurrent-neuroimaging-and-facial-electromyography-study
#9
JOURNAL ARTICLE
Emilio Chiappini, Claudia Massaccesi, Sebastian Korb, David Steyrl, Matthäus Willeit, Giorgia Silani
BACKGROUND: Atypical anticipation of social reward has been indicated to lie at the core of the social challenges faced by individuals with autism spectrum disorder (ASD). However, past research has yielded inconsistent results, often overlooking crucial characteristics of stimuli. Here, we investigated ASD reward processing using social and non-social tangible stimuli, carefully matched on several key dimensions. METHODS: We examined the anticipation and consumption of social (interpersonal touch) and non-social (flavored milk) rewards in 25 high-functioning ASD and 25 neurotypical adult individuals...
April 18, 2024: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://read.qxmd.com/read/38642323/rare-association-between-spinocerebellar-ataxia-and-amyotrophic-lateral-sclerosis-a-case-series
#10
JOURNAL ARTICLE
Valerio Ferrari, Matteo Conti, Roberta Bovenzi, Rocco Cerroni, Mariangela Pierantozzi, Nicola B Mercuri, Alessandro Stefani
INTRODUCTION: In this work, we describe a new case of association between SCA2 and MND. CASE REPORT: A 58-year-old man who was diagnosed with spinocerebellar ataxia type 2 presented dysphagia and a significant decline in his ability to walk, with a reduction in autonomy and the need to use a wheelchair. We performed electromyography and electroneurography of the four limbs and of the cranial district and motor-evoked potentials to study upper and lower motor neurons...
April 20, 2024: Neurological Sciences
https://read.qxmd.com/read/38641860/evaluation-of-oral-function-using-a-composite-sensor-during-maximum-lip-closure-and-swallowing-in-normal-children-and-adults
#11
JOURNAL ARTICLE
Mio Hozawa, Yuki Nakamura, Tetsuya Sotome, Tsutomu Nakajima, Mika Hanasaki, Yuki Sasakawa, Saeko Tsukuno, Yuki Yonemoto, Haruaki Hayasaki
BACKGROUND: There is growing interest in the development of objective methods for assessing lip-closing function in children. OBJECTIVE: To obtain normative data for healthy children in the developmental stages of lip closure function, we quantitatively evaluated oral movements associated with lip closure in children and adults using a composite sensor (CS). METHODS: Twenty-five normal children (11 boys, 14 girls) aged 8.8 ± 1...
April 19, 2024: Journal of Oral Rehabilitation
https://read.qxmd.com/read/38640831/can-symptoms-or-signs-of-cervical-dystonia-occur-without-abnormal-movements-of-the-head-or-neck
#12
JOURNAL ARTICLE
Mehreen Thayani, H A Jinnah
INTRODUCTION: Cervical dystonia is defined by excessive contraction of muscles that produce abnormal postures and movements of the head, neck, and sometimes the shoulders. Many affected individuals also have pain, local muscle hypertrophy, and/or abnormally increased EMG activity. However, abnormal movements are considered the defining feature. CASES: Three cases are described suggesting that some features of cervical dystonia may occur without abnormal movements...
April 16, 2024: Parkinsonism & related Disorders
https://read.qxmd.com/read/38638809/comparison-of-muscle-activity-of-the-lower-limbs-while-running-on-different-treadmill-models
#13
JOURNAL ARTICLE
Christina Kaltenbach, Albert Gollhofer, Benno M Nigg, Michael J Asmussen
Treadmill running is a common method of exercise and to study human locomotion. Research has examined the kinematics and kinetics of overground and treadmill running, but there has been less focus on the levels of muscle activity during treadmill running. We investigated if muscle activity is different while running overground compared to running on a variety of treadmills. A total of 11 healthy individuals ran at 3 speeds (2.6, 3.6, 4.5 m/s) under 4 different running conditions (3 treadmills, overground). The three treadmills included a typical home exercise treadmill, a midsize commercial research treadmill, and a large, instrumented research treadmill...
2024: Frontiers in Human Neuroscience
https://read.qxmd.com/read/38638790/the-incidence-of-residual-neuromuscular-block-in-pediatrics-a-prospective-pragmatic-multi-institutional-cohort-study
#14
JOURNAL ARTICLE
Debra J Faulk, Joelle B Karlik, Kim M Strupp, Stephanie M Tran, Mark Twite, Sorin J Brull, Myron Yaster, Thomas M Austin
Introduction Residual neuromuscular block, defined as a quantitatively measured train-of-four ratio (TOFr) <0.9, is common postoperatively. Using a pragmatic trial design, we hypothesized that qualitative and/or clinical assessment of neuromuscular block would inadequately detect residual block following antagonism with neostigmine or sugammadex. Method After IRB approval and written informed consent, 74 children (aged 2-17 years), undergoing elective surgery and receiving rocuronium, were prospectively enrolled in the study at Children's Hospital Colorado and Children's Healthcare of Atlanta...
March 2024: Curēus
https://read.qxmd.com/read/38638692/multi-layer-cnn-lstm-network-with-self-attention-mechanism-for-robust-estimation-of-nonlinear-uncertain-systems
#15
JOURNAL ARTICLE
Lin Liu, Jun Feng, Jiwei Li, Wanxin Chen, Zhizhong Mao, Xiaowei Tan
INTRODUCTION: With the help of robot technology, intelligent rehabilitation of patients with lower limb motor dysfunction caused by stroke can be realized. A key factor constraining the clinical application of rehabilitation robots is how to realize pattern recognition of human movement intentions by using the surface electromyography (sEMG) sensors to ensure unhindered human-robot interaction. METHODS: A multilayer CNN-LSTM prediction network incorporating the self-attention mechanism (SAM) is proposed, in this paper, which can extract and learn the periodic and trend characteristics of the sEMG signals, and realize the accurate autoregressive prediction of the human motion information...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38638581/sleep-deep-learner-is-taught-sleep-wake-scoring-by-the-end-user-to-complete-each-record-in-their-style
#16
JOURNAL ARTICLE
Fumi Katsuki, Tristan J Spratt, Ritchie E Brown, Radhika Basheer, David S Uygun
Sleep-wake scoring is a time-consuming, tedious but essential component of clinical and preclinical sleep research. Sleep scoring is even more laborious and challenging in rodents due to the smaller EEG amplitude differences between states and the rapid state transitions which necessitate scoring in shorter epochs. Although many automated rodent sleep scoring methods exist, they do not perform as well when scoring new datasets, especially those which involve changes in the EEG/EMG profile. Thus, manual scoring by expert scorers remains the gold standard...
2024: Sleep advances: a journal of the Sleep Research Society
https://read.qxmd.com/read/38637797/positive-effect-of-deep-diaphragmatic-breathing-training-on-gastroesophageal-reflux-induced-chronic-cough-a-clinical-randomized-controlled-study
#17
RANDOMIZED CONTROLLED TRIAL
Shanshan Niu, Tongyangzi Zhang, Wanzhen Li, Siwan Wen, Lei Dong, Shengyuan Wang, Wenbo Shi, Cuiqin Shi, Yuqin Shen, Qianchun Huang, Yaling Tan, Xianghuai Xu, Li Yu
BACKGROUND AND OBJECTIVE: To explore the efficacy of deep diaphragmatic breathing training (DEP) in patients with gastroesophageal reflux-induced chronic cough (GERC). METHODS: A randomized controlled study was conducted involving 60 GERC patients who were divided into the intervention group and the control group (each with 30 patients). Both groups received routine medication treatment for GERC, while the intervention group received DEP training additionally. Both groups were evaluated by cough symptom scores, Hull airway reflux questionnaire (HARQ), gastroesophageal reflux diagnostic questionnaire (GerdQ), generalized anxiety disorder scale-7 (GAD-7), patient health questionnaire-9 (PHQ-9), Pittsburgh sleep quality index (PSQI), the Leicester cough questionnaire (LCQ), as well as capsaicin cough sensitivity testing, B-ultrasound and surface electromyography (sEMG) of the diaphragmatic muscles before and after treatment...
April 18, 2024: Respiratory Research
https://read.qxmd.com/read/38636393/effect-of-experimentally-induced-muscle-pain-on-neuromuscular-control-of-force-production
#18
JOURNAL ARTICLE
Manoela Vieira Sousa, Márcio Goethel, Klaus M Becker, Fernando Diefenthaeler, Ricardo J Fernandes, Isabella de Santana Toro Batista, João Paulo Vilas-Boas, Ulysses Ervilha
PURPOSE: Neural and peripheral effects of induced muscle pain on explosive force production were investigated. METHODS: Nine participants performed two maximal, six explosive, and six electrical stimulations induced (twitches and octets) isometric knee extensions before and after (15 min of rest) receiving an intramuscular injection of hypertonic saline (pain inducer) or isotonic (placebo) infusions in two laboratory visits separated by 7 days. RESULTS: It was observed a reduction of peak torque production in maximal voluntary contraction in both conditions (9...
April 17, 2024: Human Movement Science
https://read.qxmd.com/read/38635774/effects-of-arousal-and-valence-on-center-of-pressure-and-ankle-muscle-activity-during-quiet-standing
#19
JOURNAL ARTICLE
Ryogo Takahashi, Naotsugu Kaneko, Hikaru Yokoyama, Atsushi Sasaki, Kimitaka Nakazawa
Emotion affects postural control during quiet standing. Emotional states can be defined as two-dimensional models comprising valence (pleasant/unpleasant) and arousal (aroused/calm). Most previous studies have investigated the effects of valence on postural control without considering arousal. In addition, studies have focused on the center of pressure (COP) trajectory to examine emotional effects on the quiet standing control; however, the relationship between neuromuscular mechanisms and the emotionally affected quiet standing control is largely unknown...
2024: PloS One
https://read.qxmd.com/read/38635525/reading-of-ingroup-politicians-smiles-triggers-smiling-in-the-corner-of-one-s-eyes
#20
JOURNAL ARTICLE
Edita Fino, Michela Menegatti, Alessio Avenanti, Monica Rubini
Spontaneous smiles in response to politicians can serve as an implicit barometer for gauging electorate preferences. However, it is unclear whether a subtle Duchenne smile-an authentic expression involving the coactivation of the zygomaticus major (ZM) and orbicularis oculi (OO) muscles-would be elicited while reading about a favored politician smiling, indicating a more positive disposition and political endorsement. From an embodied simulation perspective, we investigated whether written descriptions of a politician's smile would trigger morphologically different smiles in readers depending on shared or opposing political orientation...
2024: PloS One
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