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https://www.readbyqxmd.com/read/28340160/safety-of-fluoroscopy-guided-transseptal-approach-for-ablation-of-left-sided-arrhythmias
#1
Zviad Matoshvili, Hamid Bastani, Tara Bourke, Frieder Braunschweig, Nikola Drca, Kristjan Gudmundsson, Per Insulander, Anette Jemtrén, Göran Kennebäck, Ott Saluveer, Jonas Schwieler, Jari Tapanainen, Christer Wredlert, Mats Jensen-Urstad
Aims: The transseptal approach is used for left atrial access during the ablation of atrial fibrillation (AF) and other left-sided arrhythmia substrates. Transseptal puncture (TP) is commonly performed with fluoroscopic guidance, contrast injection, and pressure monitoring. In many centres, additional techniques [intracardiac echocardiography (ICE), transoesophageal echocardiography (TEE), radiofrequency needle] are used to facilitate TP but its use adds costs. In this retrospective study, we studied the safety and complication rate when TP was routinely done with fluoroscopic guidance, contrast injection, and pressure monitoring using ICE or TEE only in selected cases...
March 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28339032/clc-7-ostm1-contribute-to-the-ability-of-tea-polyphenols-to-maintain-bone-homeostasis-in-c57bl-6-mice-protecting-against-fluorosis
#2
Bing-Yun Li, Yan-Hui Gao, Jun-Rui Pei, Yan-Mei Yang, Wei Zhang, Dian-Jun Sun
Epidemiological investigations indicate that certain ingredients in tea bricks can antagonize the adverse effects of fluoride. Tea polyphenols (TPs), the most bioactive ingredient in tea bricks, have been demonstrated to be potent bone-supporting agents. ClC‑7 is known to be crucial for osteoclast (OC) bone resorption. Thus, in this study, we investigated the potential protective effects of TPs against fluorosis using a mouse model and explored the underlying mechanisms with particular focus on ClC‑7...
March 22, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28337284/hepatoprotective-effects-of-gentianella-turkestanerum-extracts-on-acute-liver-injury-induced-by-carbon-tetrachloride-in-mice
#3
Jianghua Yang, Dandan Zhu, Bowei Ju, Xiangying Jiang, Junping Hu
Objective: To investigate the contents of secoiridoid compounds (i.e. sweroside, swertiamarin and gentiopicrin) from Gentianella turkestanerum extracts, and the potential effects of G. turkestanerum extracts against carbon tetrachloride (CCl4) induced liver injury in mice. Methods: The contents of swertiamarin, gentiopicroside and sweroside from different G. turkestanerum extracts were determined with high performance liquid chromatography (HPLC). CCl4 was used to induce acute liver injury in mice. The serum aspartate amino transferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total protein (TP), total bilirubin (TB), superoxide dismutase (SOD), malondialdehyde (MDA), glutathione transferase (GSH) and catalase (CAT) were measured...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28333054/removal-of-organic-phosphorus-and-formaldehyde-in-glyphosate-wastewater-by-cwo-and-the-lime-catalyzed-formose-reaction
#4
Bo Xing, Honglin Chen, Xiaoming Zhang
Glyphosate (PMG) wastewater with 40-600 mg/L organic phosphorus (OP) and 1-4% CH2O was treated by catalytic wet oxidation (CWO) and the lime-catalyzed formose reaction to remove total phosphorus (TP) and improve biodegradability. Activated carbons (ACs) modified by H2O2 oxidation and thermal treatment with melamine were used as CWO catalysts and characterized by N2 adsorption/desorption and XPS. The CWO experiments were performed in an autoclave reactor at 110-130 °C and 1.0 MPa. The modified AC showed higher catalytic activity than the parent AC due to the introduction of nitrogen-containing functional groups, exhibited over 90% OP removal for various real PMG wastewaters, and had good stability for 20 consecutive CWO runs...
March 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28332469/marrying-step-feed-with-clarifier-improvements-increase-wet-weather-capacity-integrated-methodology
#5
Glen T Daigger John S Siczka Thomas F Smith David A Frank J A McCorquodale
The need to increase the peak wet weather secondary treatment capacity of the City of Akron, OH, Water Reclamation Facility (WRF) provided the opportunity to test an integrated methodology for maximizing the peak wet weather secondary treatment capacity of activated sludge systems. An initial investigation, consisting of process modeling of the secondary treatment system and computational fluid dynamics (CFD) analysis of the existing relatively shallow secondary clarifiers (3.3 and 3.7 m sidewater depth in 30...
March 22, 2017: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28331914/effects-and-mechanisms-of-a-new-multivitamin-on-chronic-metabolic-syndromes-and-aging
#6
Su-Xi Wu, Xuewei Jiang, Yu-Ying Liu, Lin-Feng Chen, Jun Tao
BACKGROUND: Increased occurrence of chronic syndromes has prompted researchers to investigate and develop drugs and methods for controlling chronic syndromes with a view to improve human health and reduce early aging. MATERIAL AND METHODS: Human trials: After the allotted multivitamin pills or placebo pills had been taken for a stipulated period of about 2 months, the volunteers filled out feedback forms on curative effects of the pills in line with the health examination reports...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28331578/trophic-discrimination-factor-of-nitrogen-isotopes-within-amino-acids-in-the-dobsonfly-protohermes-grandis-megaloptera-corydalidae-larvae-in-a-controlled-feeding-experiment
#7
Naoto F Ishikawa, Fumio Hayashi, Yoko Sasaki, Yoshito Chikaraishi, Naohiko Ohkouchi
The trophic discrimination factor (TDF) of nitrogen isotopes ((15)N/(14)N) within amino acids, between a stream-dwelling dobsonfly larva (Protohermes grandis: Megaloptera; Corydalidae) and its diet (chironomid larvae), was determined in controlled feeding experiments. Last-instar larvae of P. grandis were collected from the Yozawa-gawa River, central Japan, and reared in the laboratory. After fed to satiation for 1 month, one group of larvae was each fed one living chironomid larva per day for 4 weeks, while a second group was starved for 8 weeks...
March 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28331526/impaired-human-immunodeficiency-virus-type-1-replicative-fitness-in-atypical-viremic-non-progressor-individuals
#8
Jan Weber, Richard M Gibson, Lenka Sácká, Dmytro Strunin, Jan Hodek, Jitka Weberová, Marcela Pávová, David J Alouani, Robert Asaad, Benigno Rodriguez, Michael M Lederman, Miguel E Quiñones-Mateu
BACKGROUND: Progression rates from initial HIV-1 infection to advanced AIDS vary significantly among infected individuals. A distinct subgroup of HIV-1-infected individuals-termed viremic non-progressors (VNP) or controllers-do not seem to progress to AIDS, maintaining high CD4(+) T cell counts despite high levels of viremia for many years. Several studies have evaluated multiple host factors, including immune activation, trying to elucidate the atypical HIV-1 disease progression in these patients; however, limited work has been done to characterize viral factors in viremic controllers...
2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/28331337/serum-liver-enzymes-serve-as-prognostic-factors-in-patients-with-intrahepatic-cholangiocarcinoma
#9
Chenyue Zhang, Haiyong Wang, Zhouyu Ning, Litao Xu, Liping Zhuang, Peng Wang, Zhiqiang Meng
OBJECTIVE: Liver functions, reflective of the overall status of the host, have been reported to be important factors affecting the prognosis in many types of cancers. In this study, we explored the influences of liver enzymes albumin (ALB), globulin (GELO), total protein (TP), alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL), direct bilirubin (DBIL), gamma glutamyltranspeptidase (GGT), and lactate dehydrogenase (LDH) on the overall survival (OS) in a number of 173 patients with intrahepatic cholangiocarcinoma (ICC)...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28330260/impact-of-forest-vegetation-on-soil-characteristics-a-correlation-between-soil-biological-and-physico-chemical-properties
#10
L R Chandra, S Gupta, V Pande, N Singh
Temperate and dry deciduous forest covers major portion of terrestrial ecosystem in India. The two forest types with different dominant tree species differ in litter quality and root exudates, thereby exerting species-specific impact on soil properties and microbial activity. This study aims to examine the influence of forest type or dominant tree species on soil physico-chemical properties and its relationship with microbial characters in temperate and dry deciduous forest types. We assessed soil physico-chemical properties among five different sites located within the selected forest stand covered by different dominant species...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28329408/effects-of-spray-drying-parameters-on-in-vitro-functional-properties-of-camu-camu-myrciaria-dubia-mc-vaugh-a-typical-amazonian-fruit
#11
Alice Fujita, Volnei Brito Souza, Luis Daniel Daza, Carmen Silvia Fávaro-Trindade, Daniel Granato, Maria Inés Genovese
Camu-camu (Myrciaria dubia) fruit is a rich source of bioactive compounds but its shelf life is rather short. Therefore, this study was aimed to evaluate the effect of inlet air temperature (T) and concentration (C) of maltodextrin and arabic gum on the spray-drying process of commercial camu-camu pulps (São Paulo and Manaus). Moisture, solubility, total phenolics (TP), ascorbic acid (AA), and proanthocyanidins (PAC) contents, and in vitro antioxidant capacity of the powders (FRAP, DPPH, Folin-Ciocalteu's reducing capacity were measured)...
March 22, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28326823/tp-e-interval-and-tp-e-qt-ratio-before-and-after-catheter-ablation-in-patients-with-premature-ventricular-complexes
#12
Çağrı Yayla, Fırat Özcan, Dursun Aras, Osman Turak, Özcan Özeke, Serkan Çay, Serkan Topaloğlu
AIM: Tp-e/QT ratio is a novel marker of ventricular repolarization. The aim of the study is to evaluate the Tp-e interval and Tp-e/QT ratio before and after radiofrequency ablation (RFA) for patients with frequent premature ventricular complexes (PVCs). PATIENTS & METHODS: The study included 151 consecutive patients who underwent RFA for treatment of symptomatic frequent PVCs. RESULTS: Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio (all p < 0...
March 14, 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/28324353/the-fast-d-protocol-a-simple-method-to-rule-out-traumatic-vascular-injuries-of-the-lower-extremities
#13
Miguel Angel Montorfano, Lisandro Miguel Montorfano, Federico Perez Quirante, Federico Rodríguez, Leonardo Vera, Luca Neri
BACKGROUND: The aim of this study is to assess the accuracy of a Fast Doppler protocol for the examination of an injured lower limb, namely 2-Point Fast Doppler (2PFD), in order to rapidly triage arterial lesions after penetrating trauma. METHODS: The presence of flow and the aspects of the Doppler waveform of the dorsalis pedis artery (DPA) and posterior tibial artery (PTA) of the injured lower limb (2PFD) were evaluated immediately before the execution of a standardized Color Duplex Doppler (SD) evaluation in 149 limbs of 140 patients with gunshot penetrating injuries...
December 2017: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/28320742/development-of-lc3-gabarap-sensors-containing-a-lir-and-a-hydrophobic-domain-to-monitor-autophagy
#14
You-Kyung Lee, Yong-Woo Jun, Ha-Eun Choi, Yang Hoon Huh, Bong-Kiun Kaang, Deok-Jin Jang, Jin-A Lee
Macroautophagy allows for bulk degradation of cytosolic components in lysosomes. Overexpression of GFP/RFP-LC3/GABARAP is commonly used to monitor autophagosomes, a hallmark of autophagy, despite artifacts related to their overexpression. Here, we developed new sensors that detect endogenous LC3/GABARAP proteins at the autophagosome using an LC3-interacting region (LIR) and a short hydrophobic domain (HyD). Among HyD-LIR-GFP sensors harboring LIR motifs of 34 known LC3-binding proteins, HyD-LIR(TP)-GFP using the LIR motif from TP53INP2 allowed detection of all LC3/GABARAPs-positive autophagosomes...
March 20, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28320417/impaired-human-immunodeficiency-virus-type-1-replicative-fitness-in-atypical-viremic-non-progressor-individuals
#15
Jan Weber, Richard M Gibson, Lenka Sácká, Dmytro Strunin, Jan Hodek, Jitka Weberová, Marcela Pávová, David J Alouani, Robert Asaad, Benigno Rodriguez, Michael M Lederman, Miguel E Quiñones-Mateu
BACKGROUND: Progression rates from initial HIV-1 infection to advanced AIDS vary significantly among infected individuals. A distinct subgroup of HIV-1-infected individuals-termed viremic non-progressors (VNP) or controllers-do not seem to progress to AIDS, maintaining high CD4(+) T cell counts despite high levels of viremia for many years. Several studies have evaluated multiple host factors, including immune activation, trying to elucidate the atypical HIV-1 disease progression in these patients; however, limited work has been done to characterize viral factors in viremic controllers...
March 20, 2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/28320107/pre-conditioning-with-tanshinone-iia-attenuates-the-ischemia-reperfusion-injury-caused-by-liver-grafts-via-regulation-of-hmgb1-in-rat-kupffer-cells
#16
Xuanfei Li, Yakun Wu, Wenfeng Zhang, Jianping Gong, Yao Cheng
OBJECTIVE: We have evaluated the protective mechanism of tanshinone IIA in ischemia/reperfusion injury (IRI) induced by liver grafts, revealing novel supplementary immunotherapy for liver transplantation. METHODS: The tanshinone IIA preconditioning group (TP group) was pretreated with tanshinone IIA via intraperitoneal injection for 1 week before receiving orthotopic liver transplantation with hepatic arterial ischemia for 30min. The sham-operation group (SO group), control graft group (CG group) and IRI group were pretreated with an equivalent volume of normal saline...
March 18, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28319771/a-fancy-eco-compatible-wastewater-treatment-system-green-bio-sorption-reactor
#17
Yaqian Zhao, Ranbin Liu, Jinhui Zhao, Lei Xu, Caroline Sibille
A novel concept was proposed and preliminarily investigated by embedding alum sludge-based constructed wetland into conventional activated sludge system in terms of Green Bio-sorption Reactor (GBR). This novel GBR inherited the aesthetic value of constructed wetland and owned the robust phosphorus (P) adsorption along with the benefit of carriers' addition (dewatered alum sludge). The preliminary demonstration was conducted in a lab-scale sequencing batch reactor (SBR) system without biological phosphorus removal process...
March 9, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28318691/evaluation-of-simulated-dredging-to-control-internal-phosphorus-release-from-sediments-focused-on-phosphorus-transfer-and-resupply-across-the-sediment-water-interface
#18
Juhua Yu, Shiming Ding, Jicheng Zhong, Chengxin Fan, Qiuwen Chen, Hongbin Yin, Lei Zhang, Yinlong Zhang
Sediment dredging is an effective restoration method to control the internal phosphorus (P) loading of eutrophic lakes. However, the core question is that the real mechanism of dredging responsible for sediment internal P release still remains unclear. In this study, we investigated the P exchange across the sediment-water interface (SWI) and the internal P resupply ability from the sediments after dredging. The study is based on a one-year field simulation study in Lake Taihu, China, using a Rhizon soil moisture sampler, high-resolution dialysis (HR-Peeper), ZrO-Chelex diffusive gradients in thin film (ZrO-Chelex DGT), and P fractionation and adsorption isotherm techniques...
March 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28318297/impacts-of-vegetation-and-temperature-on-the-treatment-of-domestic-sewage-in-constructed-wetlands-incorporated-with-ferric-carbon-micro-electrolysis-material
#19
Qingwei Zhou, Hui Zhu, Gary Bañuelos, Baixing Yan, Yinxiu Liang, Jing Yu, Huai Li
Ferric-Carbon Micro-Electrolysis (Fe/C-M/E) material had been widely used for the pretreatment of wastewater. Therefore, we hypothesized that Fe/C-M/E material could enhance the treatment of domestic sewage when integrated into CWs. In this study, constructed wetlands (CWs) integrated with Fe/C-M/E material were developed. During the experiment of vegetation influence, percentages of NH4(+)-N, NO3(-)-N, TN, and COD removed in polyculture (W1) were up to 91.8%, 97.0%, 92.3%, and 85.4%, respectively, which were much higher than those in Lythrum salicaria monoculture (W2) and Canna indica monoculture (W3)...
March 20, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28318112/diagnostic-dilemmas-and-pitfalls-in-thinprep-%C3%A2-cytology-of-breast-fine-needle-aspiration-biopsy-report-of-six-cases-with-histological-correlates
#20
Jose Victor Scarpa Carniello, Fresia Pareja, Maria Laureana Santos-Zabala, Marcia Edelweiss
Fine needle aspirations (FNA) of the breast for primary diagnoses have become less popular in the USA and are usually performed for lesions with low or extremely high clinical suspicion. They are also performed for lesions in close proximity to a breast implant. Liquid-based cytological preparations, such as ThinPrep(®) (TP), provide a practical alternative to clinicians who are performing FNA. Using a selection of cases that represent challenging diagnoses, we describe common diagnostic pitfalls of breast FNA that are specifically associated with this preparation...
March 20, 2017: Diagnostic Cytopathology
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