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https://www.readbyqxmd.com/read/29471483/transfer-accuracy-of-two-indirect-bonding-techniques-an-in-vitro-study-with-3d-scanned-models
#1
Johanna Schmid, Daniel Brenner, Wolfgang Recheis, Philipp Hofer-Picout, Martin Brenner, Adriano G Crismani
Background and objectives: Indirect bonding (IDB) proved to be an effective method for appropriate bracket positioning in patients. Different methods and materials are available for fabricating transfer trays. This in vitro study was designed to measure and compare the transfer accuracy of two common IDB methods. Materials and methods: Sixty stone models were fabricated and separated in two groups of 30 models each (15 working models, 15 patient models). After placing brackets on the working models, 30 IDB trays were made: 15 silicone (method I) and 15 double-vacuum forms (method II)...
February 19, 2018: European Journal of Orthodontics
https://www.readbyqxmd.com/read/29471471/cohort-profile-maternal-mental-health-and-child-development-in-situations-of-past-violent-conflict-and-ongoing-adversity-the-dili-birth-cohort-study
#2
W A Tol, S J Rees, A K Tay, N Tam, A da Costa Saldanha Segurado, Z M da Costa, E S da Costa Soares, A da Costa Alves, N Martins, D M Silove
No abstract text is available yet for this article.
February 1, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29471429/comparison-of-3-methods-for-estimating-enteric-methane-and-carbon-dioxide-emission-in-nonlactating-cows
#3
M Doreau, M Arbre, Y Rochette, C Lascoux, M Eugène, C Martin
Among techniques for estimating enteric methane (CH4) emission by ruminants, open-circuit respiration chambers (OC), the use of a gas tracer (SF6) and the GreenFeed device (GF) are the most commonly used. In this study, we compared these techniques in 8 dry cows receiving a diet made of 70% hay and 30% concentrates given in limited and constant amounts, in a 15-week experiment. Two periods in free stalls for SF6 and GF and in chambers for OC were used; in addition, SF6 was determined in chambers for 1 period...
February 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471419/true-lumen-and-false-lumen-diameter-changes-in-the-downstream-aorta-after-frozen-elephant-trunk-implantation
#4
Tim Berger, Maximilian Kreibich, Julia Morlock, Stoyan Kondov, Johannes Scheumann, Fabian A Kari, Bartosz Rylski, Matthias Siepe, Friedhelm Beyersdorf, Martin Czerny
OBJECTIVES: To evaluate early and mid-term clinical outcomes and to assess the potential of the frozen elephant trunk technique to induce remodelling of downstream aortic segments in acute and chronic thoracic aortic dissections. METHODS: Over a 4-year period, 65 patients (48 men, aged 61 ± 12 years) underwent total aortic arch replacement using the frozen elephant trunk technique for acute (n = 31) and chronic (n = 34) thoracic aortic dissections at our institution...
February 19, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29471416/anti-interleukin-6-receptor-tocilizumab-in-refractory-uveitis-associated-with-beh%C3%A3-et-s-disease-multicentre-retrospective-study
#5
Belén Atienza-Mateo, Vanesa Calvo-Río, Emma Beltrán, Lucía Martínez-Costa, Elia Valls-Pascual, Marisa Hernández-Garfella, Antonio Atanes, Miguel Cordero-Coma, Joan Miquel Nolla, Carmen Carrasco-Cubero, Javier Loricera, María C González-Vela, Nuria Vegas-Revenga, Carlos Fernández-Díaz, Rosalía Demetrio-Pablo, Lucía C Domínguez-Casas, José Luis Martín-Varillas, Natalia Palmou-Fontana, José L Hernández, Miguel Á González-Gay, Ricardo Blanco
Objective: To assess the efficacy of tocilizumab (TCZ) in refractory uveitis of Behçet's disease (BD). Methods: Multicentre study of patients with BD-associated uveitis. Patients were refractory to conventional and biologic immunosuppressive drugs. The main outcome measures were intraocular inflammation, macular thickness, visual acuity and corticosteroid-sparing effects. Results: We studied 11 patients (7 men) (20 affected eyes); median age 35 years...
February 19, 2018: Rheumatology
https://www.readbyqxmd.com/read/29471411/mechanisms-underpinning-the-polypharmacy-effects-of-medications-in-psychiatry
#6
Chiara C Bortolasci, Briana Spolding, Edward Callaly, Sheree Martin, Bruna Panizzutti, Srisaiyini Kidnapillai, Timothy Connor, Kyoko Hasebe, Mohammadreza Mohebbi, Olivia M Dean, Sean L McGee, Seetal Dodd, Laura Gray, Michael Berk, Ken Walder
Background: Bipolar disorder (BD) is a mental health condition with progressive social and cognitive function disturbances. Most patients' treatments are based on polypharmacy, but with no biological basis and little is known of the drugs' interactions. The aim of this study was to analyse the effects of lithium, valproate, quetiapine and lamotrigine, and the interactions between them, on markers of inflammation, bioenergetics, mitochondrial function and oxidative stress in neuron-like cells (NT2) and microglial cells...
February 19, 2018: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29471387/heavy-cannabis-use-associated-with-reduction-in-activated-and-inflammatory-immune-cell-frequencies-in-antiretroviral-therapy-treated-human-immunodeficiency-virus-infected-individuals
#7
Jennifer A Manuzak, Toni M Gott, Jay S Kirkwood, Ernesto Coronado, Tiffany Hensley-McBain, Charlene Miller, Ryan K Cheu, Ann C Collier, Nicholas T Funderburg, Jeffery N Martin, Michael C Wu, Nina Isoherranen, Peter W Hunt, Nichole R Klatt
Background: Cannabis is a widely used drug in the United States, and the frequency of cannabis use in the human immunodeficiency virus (HIV)-infected population is disproportionately high. Previous human and macaque studies suggest that cannabis may have an impact on plasma viral load; however, the relationship between cannabis use and HIV-associated systemic inflammation and immune activation has not been well defined. Methods: The impact of cannabis use on peripheral immune cell frequency, activation, and function was assessed in 198 HIV-infected, antiretroviral-treated individuals by flow cytometry...
February 17, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29471386/first-report-of-ctx-m-15-salmonella-typhi-from-england
#8
Gauri S Godbole, Martin R Day, Saraswathi Murthy, Marie A Chattaway, Satheesh Nair
No abstract text is available yet for this article.
February 17, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29471370/competitive-ability-of-capsella-species-with-different-mating-systems-and-ploidy-levels
#9
Sandra Petrone Mendoza, Martin Lascoux, Sylvain Glémin
Background and Aims: Capsella is a model genus for studying the transition from outcrossing to selfing, with or without change in ploidy levels. The genomic consequences and changes in reproductive traits (selfing syndrome) associated with these shifts have been studied in depth. However, potential ecological divergence among species of the genus has not been determined. Among ecological traits, competitive ability could be relevant for selfing evolution, as selfing has been shown to be statistically associated with reduced competitiveness in a recent meta-analysis...
February 17, 2018: Annals of Botany
https://www.readbyqxmd.com/read/29471339/the-role-of-the-ngdo-coordination-group-for-the-elimination-of-onchocerciasis
#10
Elizabeth Elhassan, Yaobi Zhang, Simon Bush, David Molyneux, Martin K H Kollmann, Yao Sodahlon, Frank Richards
The NGDO Coordination Group for the Control of Onchocerciasis was launched in 1992, and with the paradigm shift from control of disease to elimination of onchocerciasis transmission, the Group shifted its orientation to that new paradigm in 2013. It also changed its name, replacing 'control' with 'elimination.' In doing so, the Group has repositioned itself to build on the successes of the past to finish the job it began over 25 years ago.
March 1, 2018: International Health
https://www.readbyqxmd.com/read/29471333/genomic-dissection-of-enhancers-uncovers-principles-of-combinatorial-regulation-and-cell-type-specific-wiring-of-enhancer-promoter-contacts
#11
Verena Thormann, Maika C Rothkegel, Robert Schöpflin, Laura V Glaser, Petar Djuric, Na Li, Ho-Ryun Chung, Kevin Schwahn, Martin Vingron, Sebastiaan H Meijsing
No abstract text is available yet for this article.
February 19, 2018: Nucleic Acids Research
https://www.readbyqxmd.com/read/29471316/influence-of-prior-knowledge-of-human-papillomavirus-status-on-the-performance-of-cytology-screening
#12
Toni Ricardo Martins, Adhemar Longatto-Filho, Diane Cohen, Juliana Yukari Kodaira Viscondi, Luiz Mario Fuza, Lise Cury, Luisa Lina Villa, José Eduardo Levi, José Eluf-Neto
Objectives: This study aimed to evaluate the influence of prior knowledge of human papillomavirus (HPV) status in cervical cytopathology readings. Methods: Participants comprised 2,376 women who underwent parallel cytology and HPV-DNA testing. Smears were read twice by the same team, first with previous knowledge of HPV-DNA status. Results: Overall, 239 (10.2%) smears had their cytology classification altered by the HPV-informed review. Cytology readings with prior knowledge of the HPV status revealed 10...
February 17, 2018: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29471274/accession-specific-life-strategies-affect-responses-in-leaves-of-arabidopsis-thaliana-plants-exposed-to-excess-cu-and-cd
#13
Rafaela Amaral Dos Reis, Els Keunen, Miguel Pedro Mourato, Luísa Louro Martins, Jaco Vangronsveld, Ann Cuypers
The natural accession Columbia (Col-0) is considered as the reference genome of the model plant Arabidopsis thaliana. Nonetheless, Col-0 plants are more sensitive to excess copper (Cu) and cadmium (Cd) than other widely used accessions such as Wassilewskija (Ws) plants. In the current study, this accession-specific metal sensitivity is further explored by comparing the responses in leaves of Col-0 and Ws plants exposed to excess Cu and Cd. Our results suggest that different life strategies favored by both accessions under physiological conditions affect their response to metal exposure...
February 6, 2018: Journal of Plant Physiology
https://www.readbyqxmd.com/read/29471132/high-intensity-body-weight-training-is-comparable-to-combined-training-in-changes-in-muscle-mass-physical-performance-inflammatory-markers-and-metabolic-health-in-postmenopausal-women-at-high-risk-for-type-2-diabetes-mellitus-a-randomized-controlled-clinical
#14
Fernanda Maria Martins, Aletéia de Paula Souza, Paulo Ricardo Prado Nunes, Márcia Antoniazi Michelin, Eddie Fernando Candido Murta, Elisabete Aparecida Mantovani Rodrigues Resende, Erick Prado de Oliveira, Fábio Lera Orsatti
OBJECTIVE: This study compared the effects of 12 weeks of high-intensity interval body weight training (HIBWT) with combined training (COMT; aerobic and resistance exercises on body composition, a 6-minute walk test (6MWT; physical performance), insulin resistance (IR) and inflammatory markers in postmenopausal women (PW) at high risk of type 2 diabetes mellitus (TDM2). METHODS: In this randomized controlled clinical study, 16 PW at high risk of TDM2 were randomly allocated into two groups: HIBWT (n = 8) and COMT (n = 8)...
February 19, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29471099/the-dynamics-of-error-processing-in-the-human-brain-as-reflected-by-high-gamma-activity-in-noninvasive-and-intracranial-eeg
#15
Martin Völker, Lukas D J Fiederer, Sofie Berberich, Jiří Hammer, Joos Behncke, Pavel Kršek, Martin Tomášek, Petr Marusič, Peter C Reinacher, Volker A Coenen, Moritz Helias, Andreas Schulze-Bonhage, Wolfram Burgard, Tonio Ball
Error detection in motor behavior is a fundamental cognitive function heavily relying on cortical information processing. Neural activity in the high-gamma frequency band (HGB) closely reflects such local cortical processing, but little is known about its role in error processing, particularly in the healthy human brain. Here we characterize the error-related response of the human brain based on data obtained with noninvasive EEG optimized for HGB mapping in 31 healthy subjects (15 females, 16 males), and additional intracranial EEG data from 9 epilepsy patients (4 females, 5 males)...
February 19, 2018: NeuroImage
https://www.readbyqxmd.com/read/29470978/contractile-responses-to-endothelin-1-are-regulated-by-pkc-phosphorylation-of-cardiac-myosin-binding-protein-c-in-rat-ventricular-myocytes
#16
Ioannis Smyrnias, Normann Goodwin, Dagmar Wachten, Jonas Skogestad, Jan Magnus Aronsen, Emma L Robinson, Kateryna Demydenko, Anne Segonds-Pichon, David Oxley, Sakthivel Sadayappan, Karin Sipido, Martin D Bootman, H Llewelyn Roderick
The shortening of sarcomeres that co-ordinates the pump function of the heart is stimulated by electrically-mediated increases in [Ca2+ ]. This process of excitation-contraction coupling (ECC) is subject to modulation by neurohormonal mediators that tune the output of the heart to meet the needs of the organism. Endothelin-1 (ET-1) is a potent modulator of cardiac function with effects on contraction amplitude, chronotropy and automaticity. The actions of ET-1 are evident during normal adaptive physiological responses and increased under pathophysiological conditions, such as following myocardial infarction and during heart failure, where ET-1 levels are elevated...
February 19, 2018: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/29470953/cat-preantral-follicle-survival-after-prolonged-cooled-storage-followed-by-vitrification
#17
Jorge Luis Araújo Martins, Maria Denise Lopes, Fabiana Ferreira de Souza, Fabio Sossai Possebon, Gudrun Wibbelt, Katarina Jewgenow
The aim of this study was to investigate the impact of prolonged storage at 4 °C on survival of cat preantral follicles (PAFs) pre- and post-vitrification. Ovaries were obtained from 12 queens and transported at 4 ºC within 2-6 h. Parts of the ovaries were stored for an additional 24 h or 72 h. The ovarian cortex was dissected, analyzed for viability (neutral red - NR) and morphology (histology - HE and ultrastructural analysis by TEM) and vitrified. We used 2 mm biopsy punches to obtain equal size pieces as the experimental units...
February 19, 2018: Cryobiology
https://www.readbyqxmd.com/read/29470820/the-impact-of-intraoperative-re-resection-of-a-positive-bile-duct-margin-on-clinical-outcomes-for-hilar-cholangiocarcinoma
#18
Xu-Feng Zhang, Malcolm H Squires, Fabio Bagante, Cecilia G Ethun, Ahmed Salem, Sharon M Weber, Thuy Tran, George Poultsides, Andre Y Son, Ioannis Hatzaras, Linda Jin, Ryan C Fields, Matthew Weiss, Charles Scoggins, Robert C G Martin, Chelsea A Isom, Kamron Idrees, Harveshp D Mogal, Perry Shen, Shishir K Maithel, Carl R Schmidt, Timothy M Pawlik
BACKGROUND: The impact of re-resection of a positive intraoperative bile duct margin on clinical outcomes for resectable hilar cholangiocarcinoma (HCCA) remains controversial. We sought to define the impact of re-resection of an initially positive frozen-section bile duct margin on outcomes of patients undergoing surgery for HCCA. METHODS: Patients who underwent curative-intent resection for HCCA between 2000 and 2014 were identified at 10 hepatobiliary centers...
February 22, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29470803/correction-to-chronic-granulomatous-disease-in-a-brazilian-patient-mimetizing-sarcoidosis
#19
Paola U Facco, Michele Baziotti Man, Cristiane Martin, Angelo Sementilli, Luiza F Rocha, Maria Celia C Ciaccia, José Roberto P Almeida, Sandra Dinato, Paola Vendramini, Ellen O Dantas, Nuria Zurro, Antonio Condino-Neto, Vera E V Rullo
The original version of abstract PO-162 "Chronic Granulomatous Disease in a Brazilian Patient Mimetizing Sarcoidosis" incorrectly listed the name of the second author as Micheli Barsioti. The correct spelling of the author's name is Michele Baziotti Man.
February 22, 2018: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/29470777/pleiotropic-effects-of-heparins-does-anticoagulant-treatment-increase-survival-in-cancer-patients
#20
REVIEW
I García-Escobar, C Beato-Zambrano, J Muñoz Langa, E Brozos Vázquez, B Obispo Portero, D Gutiérrez-Abad, A J Muñoz Martín
The association between venous thromboembolism (VTE) and cancer has been recognized for more than 100 years. Numerous studies have been performed to investigate strategies to decrease VTE incidence and to establish whether treating VTE impacts cancer progression and overall survival. Accordingly, it is important to understand the role of the hemostatic system in tumorigenesis and progression, as there is abundant evidence associating it with cell survival and proliferation, tumor angiogenesis, invasion, and dissemination, and metastasis formation...
February 22, 2018: Clinical & Translational Oncology
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