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https://www.readbyqxmd.com/read/28212515/combination-of-aldh2-and-adh1b-polymorphisms-is-associated-with-smoking-initiation-a-large-scale-cross-sectional-study-in-a-japanese-population
#1
Hiroyuki Masaoka, Hidemi Ito, Silvano Gallus, Miki Watanabe, Akira Yokomizo, Masatoshi Eto, Keitaro Matsuo
BACKGROUND: Aldehyde dehydrogenase 2 (ALDH2; rs671, Glu504Lys) and alcohol dehydrogenase 1B (ADH1B; rs1229984, His47Arg) polymorphisms are known to strongly influence alcohol drinking behavior. Given evidence of an association between smoking and drinking behaviors, we hypothesized that ALDH2/ADH1B polymorphisms might also be associated with smoking initiation, and conducted a cross-sectional study to examine this hypothesis. METHODS: Study subjects were first-visit outpatients diagnosed not to have cancer at Aichi Cancer Center Hospital between 2001 and 2005, including 4141 never smokers and 2912 ever smokers...
February 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28177898/maternal-dietary-zinc-supplementation-enhances-the-epigenetic-activated-antioxidant-ability-of-chick-embryos-from-maternal-normal-and-high-temperatures
#2
Yongwen Zhu, Xiudong Liao, Lin Lu, Wenxiang Li, Liyang Zhang, Cheng Ji, Xi Lin, Hsiao-Ching Liu, Jack Odle, Xugang Luo
The role of maternal dietary zinc supplementation in protecting the embryos from maternal hyperthermia-induced negative effects via epigenetic mechanisms was examined using an avian model (Gallus gallus). Broiler breeder hens were exposed to two maternal temperatures (21°C and 32°C) × three maternal dietary zinc treatments (zinc-unsupplemented control diet, the control diet + 110 mg zinc/kg inorganic or organic zinc) for 8 weeks. Maternal hyperthermia increased the embryonic mortality and induced oxidative damage evidenced by the elevated mRNA expressions of heat shock protein genes...
February 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/28177837/characteristics-of-expression-and-regulation-of-sirtuins-in-chicken-gallus-gallus
#3
Junxiao Ren, Naiyi Xu, Zheng Ma, Yanmin Li, Cuicui Li, Yanbin Wang, Yadong Tian, Xiaojun Liu, Xiangtao Kang
Sirtuins (SIRT1-SIRT7) are a family of NAD+-dependent protein deacetylases that are linked to post-translational regulation of many metabolic processes. There are few reports available for chicken sirtuins (designated cSIRT1-cSIRT7), whose expression and regulation in the liver have yet to be explored. In the present study, we characterized the expression and regulation of sirtuin family members in chicken liver. The results showed that the sirtuin family members in chicken share the same conserved functional SIR2 domains...
November 25, 2016: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/28138342/chicken-gallus-gallus-endogenous-retrovirus-generates-genomic-variations-in-the-chicken-genome
#4
Jinmin Lee, Seyoung Mun, Dong Hee Kim, Chun-Sung Cho, Dong-Yep Oh, Kyudong Han
BACKGROUND: Transposable elements (TEs) comprise ~10% of the chicken (Gallus gallus) genome. The content of TEs is much lower than that of mammalian genomes, where TEs comprise around half of the genome. Endogenous retroviruses are responsible for ~1.3% of the chicken genome. Among them is Gallus gallus endogenous retrovirus 10 (GGERV10), one of the youngest endogenous retrovirus families, which emerged in the chicken genome around 3 million years ago. RESULTS: We identified a total of 593 GGERV10 elements in the chicken reference genome using UCSC genome database and RepeatMasker...
2017: Mobile DNA
https://www.readbyqxmd.com/read/28130605/novel-polg-mutations-and-variable-clinical-phenotypes-in-13-italian-patients
#5
Paola Da Pozzo, Elena Cardaioli, Anna Rubegni, Gian Nicola Gallus, Alessandro Malandrini, Alessandra Rufa, Carla Battisti, Maria Alessandra Carluccio, Raffaele Rocchi, Fabio Giannini, Amedeo Bianchi, Michelangelo Mancuso, Gabriele Siciliano, Maria Teresa Dotti, Antonio Federico
POLG gene encodes the catalytic subunit of DNA polymerase gamma, essential for mitochondrial DNA (mtDNA) replication and repair. Mutations in POLG have been linked to a spectrum of clinical phenotypes, resulting in autosomal recessive or dominant mitochondrial diseases. These mutations have been associated with heterogeneous phenotypes, presenting with varying severity and at different ages of onset, ranging from the neonatal period to late adult life. We screened 13 patients for POLG mutations. All patients underwent a complete neurological examination, and in most of cases, muscle biopsy was performed...
January 27, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28117411/newborn-chicks-show-inherited-variability-in-early-social-predispositions-for-hen-like-stimuli
#6
Elisabetta Versace, Ilaria Fracasso, Gabriele Baldan, Antonella Dalle Zotte, Giorgio Vallortigara
Predispositions of newborn vertebrates to preferentially attend to living beings and learn about them are pervasive. Their disturbance (e.g. in neonates at risk for autism), may compromise the proper development of a social brain. The genetic bases of such predispositions are unknown. We use the well-known visual preferences of newly-hatched chicks (Gallus gallus) for the head/neck region of the hen to investigate the presence of segregating variation in the predispositions to approach a stuffed hen vs. a scrambled version of it...
January 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28108554/genome-wide-analysis-of-lncrna-and-mrna-expression-during-differentiation-of-abdominal-preadipocytes-in-the-chicken
#7
Tao Zhang, Xiangqian Zhang, Kunpeng Han, Genxi Zhang, Jinyu Wang, Kaizhou Xie, Qian Xue
Long non-coding RNAs (lncRNAs) regulate adipogenesis and other processes associated with metabolic tissue development and function. However, little is known about the function and profile of lncRNAs during preadipocyte differentiation in the chicken (Gallus gallus). Herein, lncRNA and mRNA expression in preadipocytes at different stages of differentiation were analyzed using RNA sequencing. A total of 1,300,074,528 clean reads and 27,023 novel lncRNAs were obtained from 12 samples. The number of genes (1,336 lncRNAs and 1,759 mRNAs; 3,095 in total) differentially expressed across various stages declined as differentiation progressed...
January 20, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28106276/crispr-cas9-mediated-deletion-of-c1eis-inhibits-chicken-embryonic-stem-cell-differentiation-into-male-germ-cells-gallus-gallus
#8
Qisheng Zuo, Kai Jin, Yingjie Wang, Jiuzhou Song, Yani Zhang, Bichun Li
We previously found that C1EIS is preferentially expressed in Chicken spermatogonial stem cells (SSCs) by RNA sequencing (RNA-seq), so our current study focused on C1EIS's role in Chicken embryonic stem cells (ESCs) differentiation into male germ cells. We constructed a CRISPR/Cas9 vector targeting C1EIS. T7 endonuclease I (T7EI) digestion method and sequencing of TA cloning were used to detect the knock-out efficiency of the Single guide RNA (sgRNA) after the cas9/gRNA vector transfected into D fibroblasts 1(DF-1), ESCs and Chicken embryos...
January 20, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28095663/morphology-and-molecular-phylogeny-of-raillietina-spp-cestoda-cyclophyllidea-davaineidae-from-domestic-chickens-in-thailand
#9
Preeyaporn Butboonchoo, Chalobol Wongsawad, Amnat Rojanapaibul, Jong-Yil Chai
Raillietina species are prevalent in domestic chickens (Gallus gallus domesticus) in Phayao province, northern Thailand. Their infection may cause disease and death, which affects the public health and economic situation in chicken farms. The identification of Raillietina has been based on morphology and molecular analysis. In this study, morphological observations using light (LM) and scanning electron microscopies (SEM) coupled with molecular analysis of the internal transcribed spacer 2 (ITS2) region and the nicotinamide adenine dinucleotide dehydrogenase subunit 1 (ND1) gene were employed for precise identification and phylogenetic relationship studies of Raillietina spp...
December 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28091661/biochemical-characterization-of-the-selenoproteome-in-gallus-gallus-via-bioinformatics-analysis-structure-function-relationships-and-interactions-of-binding-molecules
#10
Shi-Yong Zhu, Xue-Nan Li, Xiao-Chen Sun, Jia Lin, Wei Li, Cong Zhang, Jin-Long Li
Knowledge about mammalian selenoproteins is increasing. However, the selenoproteome of birds remains considerably less understood, especially concerning its biochemical characterization, structure-function relationships and the interactions of binding molecules. In this work, the SECIS elements, subcellular localization, protein domains and interactions of binding molecules of the selenoproteome in Gallus gallus were analyzed using bioinformatics tools. We carried out comprehensive analyses of the structure-function relationships and interactions of the binding molecules of selenoproteins, to provide biochemical characterization of the selenoproteome in Gallus gallus...
January 16, 2017: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/28090781/possible-role-of-central-interleukins-on-the-anorexigenic-effect-of-lipopolysaccharide-in-chicks
#11
T Tachibana, T Kodama, S Yamane, R Makino, S I Khan, M A Cline
1. The purpose of the present study was to determine if central interleukin-1β (IL1β), interleukin-6 (IL6), and interleukin-8 (IL8) affect feeding behaviour in chicks (Gallus gallus) and examine if central interleukins are related to the lipopolysaccharide (LPS)-induced anorexia. 2. Intra-abdominal (IA) injection of LPS significantly suppressed feeding behaviour and significantly increased mRNA expression of IL1β and IL8 in the diencephalon when compared to the control group, while IL6 tended to be increased...
January 16, 2017: British Poultry Science
https://www.readbyqxmd.com/read/28063017/the-photobiomodulation-effect-of-higher-fluence-808-nm-laser-therapy-with-a-flat-top-handpiece-on-the-wound-healing-of-the-earthworm-dendrobaena-veneta-a-brief-report
#12
Andrea Amaroli, Sara Ferrando, Reem Hanna, Lorenzo Gallus, Alberico Benedicenti, Sonia Scarfì, Marina Pozzolini, Stefano Benedicenti
No abstract text is available yet for this article.
January 6, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28056208/the-effect-of-photobiomodulation-on-the-sea-urchin-paracentrotus-lividus-echinodermata-by-using-higher-fluence-on-fertilization-embryogenesis-and-larval-development-an-in-vitro-study
#13
Andrea Amaroli, Chiara Gambardella, Sara Ferrando, Reem Hanna, Alberico Benedicenti, Lorenzo Gallus, Marco Faimali, Stefano Benedicenti
OBJECTIVE: The aim of this study was to investigate the photobiomodulation (PBM) effect of the 808 nm diode laser irradiation on spermatozoa, eggs, fertilized eggs, embryos, and larvae of Paracentrotus lividus, using two different power settings. BACKGROUND DATA: Studies have shown the possible use of PBM in artificial insemination. These have shown the potential effect of low-power laser irradiation on spermatozoa, while there are few studies on the effect of laser photonic energy on oocytes and almost no reports on the influence of lasers in embryogenesis...
December 30, 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28054265/assessment-of-arsenic-trioxide-in-the-heart-of-gallus-gallus-alterations-of-oxidative-damage-parameters-inflammatory-cytokines-and-cardiac-enzymes
#14
Si-Wen Li, Xiao Sun, Ying He, Ying Guo, Hong-Jing Zhao, Zhi-Jun Hou, Ming-Wei Xing
The aim of this study was to assess the effects of arsenic trioxide (As2O3) in the chicken heart, and 72 1-day-old male Hy-line chickens were fed either a commercial diet (C group) or an arsenic supplement diet containing 7.5 mg/kg (L group), 15 mg/kg (M group), or 30 mg/kg (H group) As2O3 for 90 days. The results showed that exposure to As2O3 merely lowered (P < 0.05) the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) in M and H groups at 90 days, significantly downregulated the inhibition ability of hydroxyl radicals (OH·), and upregulated (P < 0...
January 4, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28053568/occurrence-and-hat-rapd-analysis-of-gastrointestinal-helminths-in-domestic-chickens-gallus-gallus-domesticus-in-phayao-province-northern-thailand
#15
Preeyaporn Butboonchoo, Chalobol Wongsawad
The present study determined the prevalence and distribution of gastrointestinal helminths in domestic chickens (Gallus gallus domesticus) between November 2012 and August 2013. One hundred and twenty domestic chickens were purchased from villages in four districts of Phayao province; Mae Chai, Dok Khamtai, Chun and Chiang Kham. Morphological differences were used to identify the helminth species, and HAT-RAPD technique was used to differentiate among closely related species. The results revealed that the total prevalence of infection was 99...
January 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28046103/transcriptome-profiling-identifies-ribosome-biogenesis-as-a-target-of-alcohol-teratogenicity-and-vulnerability-during-early-embryogenesis
#16
Mark E Berres, Ana Garic, George R Flentke, Susan M Smith
Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disability. Individuals with FASD may exhibit a characteristic facial appearance that has diagnostic utility. The mechanism by which alcohol disrupts craniofacial development is incompletely understood, as are the genetic factors that can modify individual alcohol vulnerability. Using an established avian model, we characterized the cranial transcriptome in response to alcohol to inform the mechanism underlying these cells' vulnerability...
2017: PloS One
https://www.readbyqxmd.com/read/28032719/minichromosome-maintenance-protein-7-and-geminin-expression-prognostic-value-in-laryngeal-squamous-cell-carcinoma-in-patients-treated-with-radiotherapy-and-cetuximab
#17
Giovanni Almadori, Libero Lauriola, Antonella Coli, Francesco Bussu, Roberto Gallus, Domenico Scannone, Vincenzo Valentini, Gaetano Paludetti, Thomas E Carey, Franco O Ranelletti
BACKGROUND: Minichromosome maintenance protein 7 (MCM7) is a downstream of human epidermal growth receptor (HER1) signaling. We examined MCM7, geminin, and HER1 expression in patients with laryngeal squamous cell carcinoma (SCC) treated with radiotherapy and cetuximab. METHODS: MCM7, geminin, and HER1 were evaluated by immunohistochemistry on 61 patients with laryngeal SCC. The follow-up (median, 32.1 months; range, 2-139 months) went from the beginning of therapy to tumor progression-free survival (PFS) and death (overall survival [OS])...
December 29, 2016: Head & Neck
https://www.readbyqxmd.com/read/28029371/the-role-of-water-soluble-meconium-subfraction-and-lipid-soluble-meconium-subfraction-on-the-superior-mesenteric-artery-vasoconstriction-in-chick-embryos
#18
Serdar Şiyve, Oktay Ulusoy, Osman Z Karakuş, Nergis Murat, Mehmet E Uslu, Oğuz Ateş, Gülce Hakgüder, Mustafa Olguner, Feza M Akgür
OBJECTIVE: Intraamniotic meconium has been responsible for intestinal damage in gastroschisis and meconium-dependent intestinal ischemia has been proposed to induce additional intestinal damage in gastroschisis. This study is aimed to determine the effects of lipid and water-soluble meconium subfractions on the contractility of the superior mesenteric artery (SMA). MATERIALS AND METHODS: The study was conducted on 18-day fertilized chick embryos (Gallus Domesticus)...
October 14, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28005417/the-association-between-internet-addiction-and-personality-disorders-in-a-general-population-based-sample
#19
Sina Zadra, Gallus Bischof, Bettina Besser, Anja Bischof, Christian Meyer, Ulrich John, Hans-Jürgen Rumpf
: Background and aims Data on Internet addiction (IA) and its association with personality disorder are rare. Previous studies are largely restricted to clinical samples and insufficient measurement of IA. Methods Cross-sectional analysis data are based on a German sub-sample (n = 168; 86 males; 71 meeting criteria for IA) with increased levels of excessive Internet use derived from a general population sample (n = 15,023). IA was assessed with a comprehensive standardized interview using the structure of the Composite International Diagnostic Interview and the criteria of Internet Gaming Disorder as suggested in DSM-5...
December 2016: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/27996968/rna-sequencing-analysis-of-the-developing-chicken-retina
#20
Christophe J Langouet-Astrie, Annamarie L Meinsen, Emily R Grunwald, Stephen D Turner, Raymond A Enke
RNA sequencing transcriptome analysis using massively parallel next generation sequencing technology provides the capability to understand global changes in gene expression throughout a range of tissue samples. Development of the vertebrate retina requires complex temporal orchestration of transcriptional activation and repression. The chicken embryo (Gallus gallus) is a classic model system for studying developmental biology and retinogenesis. Existing retinal transcriptome projects have been critical to the vision research community for studying aspects of murine and human retinogenesis, however, there are currently no publicly available data sets describing the developing chicken retinal transcriptome...
December 20, 2016: Scientific Data
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