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prp and orthopedics

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https://www.readbyqxmd.com/read/27726423/plantar-fasciitis-a-comparison-of-treatment-with-intralesional-steroids-versus-platelet-rich-plasma-prp-a-randomized-blinded-study
#1
Carlos Acosta-Olivo, Jorge Elizondo-Rodriguez, Ricardo Lopez-Cavazos, Felix Vilchez-Cavazos, Mario Simental-Mendia, Oscar Mendoza-Lemus
BACKGROUND: Many treatment options for plantar fasciitis currently exist, some with great success in pain relief. The objective of our study was to compare the use of intralesional steroids with platelet-rich plasma (PRP), using pain scales and functional evaluation, in patients with plantar fasciitis who did not respond to conservative treatment. METHODS: A controlled, randomized, blinded clinical assay was performed. Patients were assigned to one of the two groups by selecting a sealed envelope...
October 11, 2016: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/27668218/the-use-of-adipose-derived-progenitor-cells-and-platelet-rich-plasma-combination-for-the-treatment-of-supraspinatus-tendinopathy-in-55-dogs-a-retrospective-study
#2
Sherman O Canapp, Debra A Canapp, Victor Ibrahim, Brittany Jean Carr, Catherine Cox, Jennifer G Barrett
OBJECTIVE: To report clinical findings and outcomes for 55 dogs with supraspinatus tendinopathy (ST) treated with adipose-derived progenitor cells and platelet-rich plasma (ADPC-PRP) therapy. METHODS: Medical records of client-owned dogs diagnosed with ST that were treated with ADPC-PRP combination therapy were reviewed from 2006 to 2013. Data collected included signalment, medical history, limb involvement, prior treatments, physical and orthopedic examination, objective temporospatial gait analysis findings, diagnostic imaging results (radiography, magnetic resonance imaging, musculoskeletal ultrasonography), arthroscopy findings, and outcome...
2016: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/27651048/protected-resident-research-time-does-not-increase-the-quantity-or-quality-of-residency-program-research-publications-a-comparison-of-3-orthopedic-residencies
#3
Chad A Krueger, Jeffery D Hoffman, George C Balazs, Anthony E Johnson, Benjamin K Potter, Philip J Belmont
INTRODUCTION: The effect of dedicated resident research time in terms of residency program research productivity remains largely unknown. We hypothesize that the quantity and quality of a residency program's peer-reviewed publications (PRPs) increase proportionately with the amount of dedicated research time given to residents. METHODS: Three residency programs (P1, P2, and P3) were examined. P1 has a mandatory research year for all residents between postgraduate years 3 and 4...
September 16, 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27599222/applications-of-platelet-rich-plasma-in-lymphedema
#4
Ahmet Akgül, Musa Cirak, Tansu Birinci
Platelet-rich plasma (PRP) is an autologous concentrated preparation of human platelets contained in a small volume of plasma that is characterized by hemostatic and tissue-repairing effects. Being enriched by various kinds of growth factors, and their tissue-repairing effects have made them the focus of attention for use in tissue regeneration. PRP has been safely used and documented in many different fields, including orthopedics, sports injuries, dental and periodontal surgery, and cosmetic, plastic, cardiovascular, general, and maxillofacial surgery...
September 6, 2016: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/27580105/effects-of-administration-of-adipose-derived-stromal-vascular-fraction-and-platelet-rich-plasma-to-dogs-with-osteoarthritis-of-the-hip-joints
#5
David A Upchurch, Walter C Renberg, James K Roush, George A Milliken, Mark L Weiss
OBJECTIVE To evaluate effects of simultaneous intra-articular and IV injection of autologous adipose-derived stromal vascular fraction (SVF) and platelet-rich plasma (PRP) to dogs with osteoarthritis of the hip joints. ANIMALS 22 client-owned dogs (12 placebo-treated [control] dogs and 10 treated dogs). PROCEDURES Dogs with osteoarthritis of the hip joints that caused signs of lameness or discomfort were characterized on the basis of results of orthopedic examination, goniometry, lameness score, the Canine Brief Pain Inventory (CBPI), a visual analogue scale, and results obtained by use of a pressure-sensing walkway at week 0 (baseline)...
September 2016: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/27552452/platelet-rich-plasma-prp-in-orthopedic-sports-medicine
#6
Ryan A Mlynarek, Andrew W Kuhn, Asheesh Bedi
The use of platelet-rich plasma (PRP) injections in the treatment of musculoskeletal conditions has become more prevalent in recent years. Current literature has exhibited that PRP injections are relatively safe and can potentially accelerate or augment the soft tissue healing process. This review presents the most current literature update on the use of PRP in the treatment of rotator cuff tears, osteoarthritis of the knee, ulnar collateral ligament tears, lateral epicondylitis, hamstring injuries, and Achilles tendinopathy...
July 2016: American Journal of Orthopedics
https://www.readbyqxmd.com/read/27512216/management-of-osteonecrosis-of-the-femoral-head-a-novel-technique
#7
Ahmed M Samy
BACKGROUND: Osteonecrosis of the femoral head (ONFH) is a debilitating disease in orthopedics, frequently progressing to femoral head collapse and osteoarthritis. It is thought to be a multifactorial disease. ONFH ultimately results in femoral head collapse in 75-85% of untreated patients. Total hip arthroplasty (THA) yields satisfactory results in the treatment of the end stage of the disease. However, disease typically affects males between the ages of 20 and 40 years and joint replacement is not the ideal option for younger patients...
July 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27394438/platelet-rich-plasma-prp-and-adipose-derived-mesenchymal-stem-cells-stimulatory-effects-on-proliferation-and-migration-of-fibroblasts-and-keratinocytes-in-vitro
#8
Talita Stessuk, Maria Beatriz Puzzi, Elinton Adami Chaim, Paulo César Martins Alves, Erich Vinicius de Paula, Andresa Forte, Juliana Massae Izumizawa, Carolina Caliári Oliveira, Fernando Frei, João Tadeu Ribeiro-Paes
The clinical use of tissue engineering associated with cell therapy is considered a new alternative therapy for the repair of chronic lesions with potential application in different medical areas, mostly in orthopedic and dermatological diseases. Platelet-rich plasma (PRP) is a rich source of growth factors and cytokines important for wound healing. Adipose-derived mesenchymal stem cells (ADSCs) have shown potential to accelerate the resolution of ulcers, to stimulate cell proliferation, and to benefit the quality of skin repair...
September 2016: Archives of Dermatological Research
https://www.readbyqxmd.com/read/27234711/autologous-platelet-rich-plasma-for-the-treatment-of-pattern-hair-loss
#9
REVIEW
Babu Singh, Lynne J Goldberg
Platelet-rich plasma (PRP) is a solution derived from whole blood that is enriched in the platelet fraction. Platelets serve as a reservoir of growth factors and cytokines. When platelets are activated in vivo, signaling molecules are released into the immediate microenvironment and activate receptors for various pathways. Historically, PRP has been applied to wound beds to promote healing of complex wounds. Over the last decade, it has served as a valuable therapeutic tool in various specialties such as maxillofacial surgery, plastic surgery, orthopedics and sports medicine...
August 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27206071/the-use-of-biologic-agents-in-athletes-with-knee-injuries
#10
Michaela Kopka, James P Bradley
Biologic agents are gaining popularity in the management of bony and soft tissue conditions about the knee. They are becoming the mainstay of nonoperative therapy in the high-demand athletic population. The most well-studied agents include platelet-rich plasma (PRP) and stem cells-both of which have shown promise in the treatment of various conditions. Animal and clinical studies have demonstrated improved outcomes following PRP treatment in early osteoarthritis of the knee, as well as in chronic patellar tendinopathy...
July 2016: Journal of Knee Surgery
https://www.readbyqxmd.com/read/27130396/impact-of-platelet-rich-plasma-injection-timing-on-healing-of-achilles-tendon-injury-in-a-rat-model
#11
Esra Çirci, Yunus Emre Akman, Erhan Şükür, Erol Rüştü Bozkurt, Tolga Tüzüner, Yusuf Öztürkmen
OBJECTIVE: The aim of this study was to evaluate the impact of the timing of platelet-rich plasma (PRP) application on the healing of Achilles tendon injury in a rat model. METHODS: Fifty-four female Sprague-Dawley rats were divided into 4 groups: PRP preparation group (n=6); Achilles tendon tear and 150 µL of PRP received on the day following the injury (PRP day 0, group 1, n=16); Achilles tendon tear and 150 µL of PRP received on the third day following injury (day 3 , group 2, n=16); Achilles tendon tear and 150 µL of saline received on the day following injury (PRP day 0, group 3, n=16)...
2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27047220/endoscopic-plantar-fasciotomy-versus-injection-of-platelet-rich-plasma-for-resistant-plantar-fasciopathy
#12
Ahmed Mohamed Ahmed Othman, Islam Hassan Ali Hegazy
BACKGROUND: Resistant plantar fasciopathy is a common orthopedic problem. AIM: Comparing two different methods of treatment. METHODS: Fifty patients with chronic resistant plantar fasciopathy were divided into two groups. The first included 23 patients treated by endoscopic release of plantar fascia (EPF) and the second included 27 patients treated by injection of platelet-rich plasma (PRP). RESULTS: In the EPF group, the average VAS improved from 8...
December 2015: Journal of Orthopaedics
https://www.readbyqxmd.com/read/26836360/platelet-rich-plasma-compared-with-other-common-injection-therapies-in-the-treatment-of-chronic-lateral-epicondylitis
#13
Tristan Rodik, Brendon McDermott
CLINICAL SCENARIO: Lateral epicondylitis (LE) is a relatively common pathology capable of producing chronic debilitation in a variety of patients. A newer treatment for orthopedic conditions is platelet-rich plasma (PrP) local injection. Focused Clinical Question: Is PrP a more appropriate injection therapy for LE than other common injections such as corticosteroid or whole blood? Summary of Key Findings: Four studies were included: 1 randomized controlled trial (RCT), 2 double-blind RCTs, and 1 cohort study...
February 2016: Journal of Sport Rehabilitation
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