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https://www.readbyqxmd.com/read/28430671/elevated-production-of-nociceptive-cc-chemokines-and-se-selectin-in-patients-with-low-back-pain-and-the-effects-of-spinal-manipulation-a-non-randomized-clinical-trial
#1
Julita A Teodorczyk-Injeyan, Marion McGregor, John J Triano, H Stephen Injeyan
BACKGROUND: The involvement of inflammatory components in the pathophysiology of low back pain is poorly understood. It has been suggested that spinal manipulative therapy (SMT) may exert anti-inflammatory effects. PURPOSE: To determine the involvement of inflammation-associated chemokines (CC series) in the pathogenesis of non-specific low back pain and to evaluate the effect of SMT on that process. METHODS: Patients presenting with non-radicular, non-specific low back pain (minimum pain score 3 on 10 point visual analogue scale, VAS) were recruited according to stringent inclusion criteria...
April 19, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28429800/straight-and-rigid-flagellar-hook-made-by-insertion-of-the-flgg-specific-sequence-into-flge
#2
Koichi D Hiraoka, Yusuke V Morimoto, Yumi Inoue, Takashi Fujii, Tomoko Miyata, Fumiaki Makino, Tohru Minamino, Keiichi Namba
The bacterial flagellar hook connects the helical flagellar filament to the rotary motor at its base. Bending flexibility of the hook allows the helical filaments to form a bundle behind the cell body to produce thrust for bacterial motility. The hook protein FlgE shows considerable sequence and structural similarities to the distal rod protein FlgG; however, the hook is supercoiled and flexible as a universal joint whereas the rod is straight and rigid as a drive shaft. A short FlgG specific sequence (GSS) has been postulated to confer the rigidity on the FlgG rod, and insertion of GSS at the position between Phe-42 and Ala-43 of FlgE actually made the hook straight...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28424312/archer-fish-jumping-prey-capture-kinematics-and-hydrodynamics
#3
Anna M Shih, Leah Mendelson, Alexandra H Techet
Smallscale archer fish, Toxotes microlepis, are best known for spitting jets of water to capture prey, but also hunt by jumping out of the water to heights of up to 2.5 body lengths. In this study, high-speed imaging and particle image velocimetry were used to characterize the kinematics and hydrodynamics of this jumping behavior. Jumping used a set of kinematics distinct from those of in-water feeding strikes and was segmented into three phases: (1) hovering to sight prey at the surface, (2) rapid upward thrust production and (3) gliding to the prey once out of the water...
April 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28423075/glass-microbeads-in-analog-models-of-thrust-wedges
#4
Taynara D'Angelo, Caroline J S Gomes
Glass microbeads are frequently used in analog physical modeling to simulate weak detachment zones but have been neglected in models of thrust wedges. Microbeads differ from quartz sand in grain shape and in low angle of internal friction. In this study, we compared the structural characteristics of microbeads and sand wedges. To obtain a better picture of their mechanical behavior, we determined the physical and frictional properties of microbeads using polarizing and scanning electron microscopy and ring-shear tests, respectively...
January 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28421100/integrated-approach-of-agri-nanotechnology-challenges-and-future-trends
#5
REVIEW
Sandhya Mishra, Chetan Keswani, P C Abhilash, Leonardo F Fraceto, Harikesh Bahadur Singh
Nanotechnology representing a new frontier in modern agriculture is anticipated to become a major thrust in near future by offering potential applications. This integrating approach, i.e., agri-nanotechnology has great potential to cope with global challenges of food production/security, sustainability and climate change. However, despite the potential benefits of nanotechnology in agriculture so far, their relevance has not reached up to the field conditions. The elevating concerns about fate, transport, bioavailability, nanoparticles toxicity and inappropriateness of regulatory framework limit the complete acceptance and inclination to adopt nanotechnologies in agricultural sector...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28420533/observer-based-consensus-of-networked-thrust-propelled-vehicles-with-directed-graphs
#6
Weiye Cang, Zhongkui Li, Hanlei Wang
In this paper, we investigate the consensus problem for networked underactuated thrust-propelled vehicles (TPVs) interacting on directed graphs. We propose distributed observer-based consensus protocols, which avoid the reliance on the measurements of translational velocities and accelerations. Using the input-output analysis, we present necessary and sufficient conditions to ensure that the observer-based protocols can achieve consensus for both the cases without and with constant communication delays, provided that the communication graph contains a directed spanning tree...
April 15, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28420152/measurement-of-pressure-fluctuations-inside-a-model-thrust-bearing-using-pvdf-sensors
#7
Andrew Youssef, David Matthews, Andrew Guzzomi, Jie Pan
Thrust bearings play a vital role in propulsion systems. They rely on a thin layer of oil being trapped between rotating surfaces to produce a low friction interface. The "quality" of this bearing affects many things from noise transmission to the ultimate catastrophic failure of the bearing itself. As a result, the direct measure of the forces and vibrations within the oil filled interface would be very desirable and would give an indication of the condition of the bearing in situ. The thickness of the oil film is, however, very small and conventional vibration sensors are too cumbersome to use in this confined space...
April 16, 2017: Sensors
https://www.readbyqxmd.com/read/28413275/comparison-of-trapezius-squeeze-test-and-jaw-thrust-as-clinical-indicators-for-laryngeal-mask-airway-insertion-in-spontaneously-breathing-children
#8
K K Dinesh Kumar, Neerja Bhardwaj, Sandhya Yaddanapudi
BACKGROUND AND AIMS: It is not known whether trapezius squeeze test (TPZ) is a better clinical test than jaw thrust (JT) to assess laryngeal mask airway (LMA) insertion conditions in children under sevoflurane anesthesia. MATERIAL AND METHODS: After the Institutional Ethics Committee approval and written informed parental consent, 124 American Society of Anesthesiologists I and II children of 2-8 years of age undergoing minor surgical procedures were randomized into TPZ and JT groups...
January 2017: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/28412164/diagnosis-and-management-of-oropharyngeal-dysphagia-among-older-persons-state-of-the-art
#9
REVIEW
Omar Ortega, Alberto Martín, Pere Clavé
Oropharyngeal dysphagia (OD) is a condition recognized by the World Health Organization and defined as the difficulty or inability to move a bolus safely and effectively from the oral cavity to the esophagus, and can include aspirations, choking, and residue. OD is pandemic among different phenotypes of older people, affecting between 27% and 91% of the population 70 years or older. Although OD can be diagnosed by well-defined clinical methods and complementary explorations, in the clinical setting OD is seldom systematically screened and treated, and awareness among the medical/geriatric community is scarce...
April 12, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28397712/design-of-hair-like-appendages-and-comparative-analysis-on-their-coordination-toward-steady-and-efficient-swimming
#10
Bokeon Kwak, Joonbum Bae
Locomotion of water beetles have been widely studied in biology owing to their remarkable swimming skills. Inspired by the oar-like legs of water beetles, designing a robot that swims under the principle of drag-powered propulsion can lead to highly agile mobility. But its motion can easily be discontinuous and jerky due to backward motions (i.e., retraction) of the legs. Here we proposed novel hair-like appendages and considered their coordination to achieve steady and efficient swimming on the water surface...
April 11, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28389560/introduction-to-the-thematic-minireview-series-host-microbiome-metabolic-interplay
#11
Ruma Banerjee
Long before the recent thrust of scientific research on the microbiome, the importance of its interface with the host was being acknowledged by practices such as probiotic supplementation e.g., after a course of antibiotics, which has the unwanted side effect of depleting commensal bacteria. The shared metabolite capital between the host and the microbiome is extensive and tightly controlled. However, despite the influence of microbial-derived metabolites on many aspects of host physiology, behavior and pathology, our understanding of this metabolic interface is still in its infancy and its therapeutic targeting is largely untapped...
April 7, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28376021/vertical-head-thrusting-in-acquired-supranuclear-vertical-ophthalmoplegia
#12
Yeon-Hee Lee, Seong-Hae Jeong, Hyo-Jung Kim, Jeong-Min Hwang, Woohyuk Lee, Ji-Soo Kim
Patients with congenital ocular motor apraxia (OMA) typically show head thrusts while attempting to shift gaze. In congenital OMA, this compensatory head motion mostly occurs in the horizontal plane. Two patients with acquired palsy of voluntary vertical gaze and continuous upward gaze deviation, one from aortic surgery and the other from multiple infarctions involving the mesodiencephalic junction, showed intermittent downward head thrusting to redirect the eyes straight ahead or downward. The head thrusting behavior improved markedly after surgical correction of the upward gaze deviation in one patient...
April 3, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28372271/effect-of-coring-conditions-on-temperature-rise-in-bone
#13
Md Monirul Islam, Xiaodu Wang
Coring is a surgical procedure in bone biopsy retrieval and dental/orthopaedic procedures, which may cause thermal damage to bone tissues adjacent to the coring zone. This study was performed to determine the temperature rise in bone by coring using a semi-empirical thermocouple approach. Concurrently, a custom-made dynamometer was used to measure the cutting and thrust forces during coring bovine cortical bone samples. The experimental results indicated that the cutting force, cutting speed, and depth of cut significantly affect the temperature rise in the cutting zone during coring process...
2017: Bio-medical Materials and Engineering
https://www.readbyqxmd.com/read/28362836/numerical-study-on-the-hydrodynamics-of-thunniform-bio-inspired-swimming-under-self-propulsion
#14
Ningyu Li, Huanxing Liu, Yumin Su
Numerical simulations are employed to study the hydrodynamics of self-propelled thunniform swimming. The swimmer is modeled as a tuna-like flexible body undulating with kinematics of thunniform type. The wake evolution follows the vortex structures arranged nearly vertical to the forward direction, vortex dipole formation resulting in the propulsion motion, and finally a reverse Kármán vortex street. We also carry out a systematic parametric study of various aspects of the fluid dynamics behind the freely swimming behavior, including the swimming speed, hydrodynamic forces, power requirement and wake vortices...
2017: PloS One
https://www.readbyqxmd.com/read/28362636/an-aerodynamic-model-for-insect-flapping-wings-in-forward-flight
#15
Jong-Seob Han, Jo Won Chang, Jae-Hung Han
This paper proposes a semi-empirical quasi-steady aerodynamic model of a flapping wing in forward flight. A total of 147 individual cases, which consisted of advance ratios J of 0 (hovering), 0.125, 0.25, 0.5, 0.75, 1 and  ∞, and angles of attack α of  -5 to 95° at intervals of 5°, were examined to extract the aerodynamic coefficients. The Polhamus leading-edge suction analogy and power functions were then employed to establish the aerodynamic model. In order to preserve the existing level of simplicity, K P and K V, the correction factors of the potential and vortex force models, were rebuilt as functions of J and α...
March 31, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28362631/the-undulatory-swimming-gait-of-elongated-swimmers-revisited
#16
Gil Iosilevskii
An undulatory swimming gait is characterized by short lateral displacement waves that propagate backwards along the body of the swimmer faster than it swims. Hydrodynamic theory of elongated bodies predicts that if the amplitude of the displacement waves does not increase toward the caudal end, the part of the swimmer posteriad of the dorso-ventrally widest point takes no part in propulsion. It also predicts that if the amplitude does increase, then the hydrodynamic propulsion efficiency suffers. Cusk eels have their widest point located in the anterior half of the body with the bulk of their locomotive muscles located posteriad of it; indeed, they swim so that the amplitude of the propulsion wave increases toward the caudal end...
March 31, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28357395/new-insights-into-the-function-of-a-versatile-class-of-membrane-molecular-motors-from-studies-of-myxococcus-xanthus-surface-gliding-motility
#17
COMMENT
Tâm Mignot, Marcelo Nöllmann
Cell motility is a central function of living cells, as it empowers colonization of new environmental niches, cooperation, and development of multicellular organisms. This process is achieved by complex yet precise energy-consuming machineries in both eukaryotes and bacteria. Bacteria move on surfaces using extracellular appendages such as flagella and pili but also by a less-understood process called gliding motility. During this process, rod-shaped bacteria move smoothly along their long axis without any visible morphological changes besides occasional bending...
March 2, 2017: Microbial Cell
https://www.readbyqxmd.com/read/28355166/synchronisation-through-learning-for-two-self-propelled-swimmers
#18
Guido Novati, Siddhartha Verma, Dmitry Alexeev, Diego Rossinelli, Wim M van Rees, Petros Koumoutsakos
The coordinated motion by multiple swimmers is a fundamental component in fish schooling. The flow field induced by the motion of each self-propelled swimmer implies non-linear hydrodynamic interactions among the members of a group. How do swimmers compensate for such hydrodynamic interactions in coordinated patterns? We provide an answer to this riddle though simulations of two, self-propelled, fish-like bodies that employ a learning algorithm to synchronise their swimming patterns. We distinguish between learned motion patterns and the commonly used a-priori specified movements, that are imposed on the swimmers without feedback from their hydrodynamic interactions...
March 29, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28350226/integration-of-care-in-the-implementation-of-the-affordable-care-act-changes-in-treatment-services-in-a-national-sample-of-centers-treating-substance-use-disorders
#19
Lydia Aletraris, Paul M Roman, Jana Pruett
This study examined patterns of medicalization in substance use disorder (SUD) that are aligned with the goals of the Affordable Care Act (ACA). Using a nationally representative sample of SUD treatment programs, we examined changes in several treatment domains. While observed changes were modest, they were in directions that support the thrust of the ACA. Specifically, we found an increase in the percentage of treatment referrals from other health care providers. We found an increase in the number of physicians for programs that did have a physician on staff, and an increase in counselors certified in treating alcohol and drug addiction...
March 28, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28347162/biomarkers-in-hepatocellular-carcinoma-an-overview
#20
Eva Juárez-Hernández, Daniel Motola-Kuba, Norberto Carlos Chávez-Tapia, Misael Uribe, Varenka Julieta Barbero-Becerra
Current methods for HCC diagnosis have not an optimal diagnostic accuracy. The detection of more than one biomarker seems to improve their individual performance and provide an accurate HCC diagnosis approach. Individual gene expression seems to influence whether or not the treatment is successful, since several molecules have interfere with cancer associated pathways and have been related to poor prognosis which condition the lack of effective treatment options. Areas covered: Novel biomarkers have been proposed as a useful tool in each patient prognosis...
March 27, 2017: Expert Review of Gastroenterology & Hepatology
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