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https://www.readbyqxmd.com/read/28529359/the-journey-of-opioid-substitution-therapy-in-india-achievements-and-challenges
#1
Ravindra Rao
Opioids are one of the most problematic illegal substances globally. Opioid abuse is associated with complications in various spheres of the user's life, his/her family, and the society. Injecting drug use (IDU) is also linked to public health problems such as HIV infection and viral hepatitis. Medications form an important cornerstone in the treatment of opioid dependence. Treatment strategies such as "detoxification" alone or long-term treatment with opioid antagonist have limited acceptability and retention rates...
January 2017: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28526466/-comparison-of-three-different-insertion-techniques-with-lma-unique%C3%A2-in-adults-results-of-a-randomized-trial
#2
Merih Eglen, Bahar Kuvaki, Ferim Günenç, Sule Ozbilgin, Semih Küçükgüçlü, Ebru Polat, Emel Pekel
BACKGROUND: The triple airway maneuver insertion technique allowed faster insertion of the LMA. This study compared three different insertion techniques of the laryngeal mask airway-Unique™. METHODS: One hundred and eighty ASA I-II patients aged 18-65 years were included into the study. Patients were randomly allocated to the standard, rotational and triple airway maneuver (triple) group. In the standard group (n=60), the LMA (Laryngeal Mask Airway) was inserted with digital intraoral manipulation...
May 16, 2017: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28505959/the-application-of-a-pre-positioned-upper-cervical-traction-mobilization-to-patients-with-painful-active-cervical-rotation-impairment-a-case-series
#3
Douglas S Creighton, Doug Marsh, Mark Gruca, Melissa Walter
BACKGROUND: Cervical mobilization and manipulation have been shown to improve cervical range of motion and pain. Cervical rotatory thrust manipulation has been associated with adverse patient reaction and damage to the V3 segment of the vertebral artery (VA). OBJECTIVE: To document and describe the effects of an upper cervical (UC) traction based mobilization on participants with restricted and painful cervical rotation and to document if the mobilization changed blood flow velocity through the vertebral artery...
May 5, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28505955/the-immediate-effects-of-manual-stretching-and-cervicothoracic-junction-manipulation-on-cervical-range-of-motion-and-upper-trapezius-pressure-pain-thresholds
#4
William J Hanney, Emilio Puentedura, Morey J Kolber, Xinliang Liu, Patrick S Pabian, Scott Cheatham
INTRODUCTION: Myofascial pain is a common impairment treated with various manual interventions including spinal thrust manipulation and stretching; however, the comparative efficacy of each intervention is uncertain. Therefore, the purpose of this investigation was to evaluate thrust manipulation targeting the cervicothoracic junction compared to a manual stretch of the upper trapezius muscle on cervical range of motion and upper trapezius pressure pain thresholds (PPTs). METHODS: Healthy participants with no significant history of neck pain were randomized into a thrust manipulation group, a stretching group, or a control group...
May 5, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28503003/characterization-of-moderate-ash-and-gas-explosions-at-santiaguito-volcano-guatemala-from-infrasound-waveform-inversion-and-thermal-infrared-measurements
#5
S De Angelis, O D Lamb, A Lamur, A J Hornby, F W von Aulock, G Chigna, Y Lavallée, A Rietbrock
The rapid discharge of gas and rock fragments during volcanic eruptions generates acoustic infrasound. Here we present results from the inversion of infrasound signals associated with small and moderate gas-and-ash explosions at Santiaguito volcano, Guatemala, to retrieve the time history of mass eruption rate at the vent. Acoustic waveform inversion is complemented by analyses of thermal infrared imagery to constrain the volume and rise dynamics of the eruption plume. Finally, we combine results from the two methods in order to assess the bulk density of the erupted mixture, constrain the timing of the transition from a momentum-driven jet to a buoyant plume, and to evaluate the relative volume fractions of ash and gas during the initial thrust phase...
June 28, 2016: Geophysical Research Letters
https://www.readbyqxmd.com/read/28492115/human-dignity-and-the-future-of-the-voluntary-active-euthanasia-debate-in-south-africa
#6
Donrich W Jordaan
The issue of voluntary active euthanasia was thrust into the public policy arena by the Stransham-Ford lawsuit. The High Court legalised voluntary active euthanasia - however, ostensibly only in the specific case of Mr Stransham-Ford. The Supreme Court of Appeal overturned the High Court judgment on technical grounds, not on the merits. This means that in future the courts can be approached again to consider the legalisation of voluntary active euthanasia. As such, Stransham-Ford presents a learning opportunity for both sides of the legalisation divide...
April 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28488002/experience-with-the-use-of-propofol-for-radiologic-imaging-in-infants-younger-than-6-months-of-age
#7
Elan Jenkins, Kiran B Hebbar, Katie K Karaga, Daniel A Hirsh, James D Fortenberry, Courtney E McCracken, Stephen F Simoneaux, Michael D Mallory, Pradip P Kamat
BACKGROUND: There is an increased risk associated with procedural sedation of infants younger than 6 months of age. The use of propofol for radiologic imaging of this age group is not well studied. OBJECTIVE: We hypothesize that adverse events are higher in the infant population receiving propofol for radiologic imaging. MATERIALS AND METHODS: A retrospective chart review was undertaken of 304 infants younger than 6 months old who received propofol for procedural sedation from October 2012 to February 2015...
May 9, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28481892/numerical-comparison-of-exhaust-plume-flow-behaviors-of-small-monopropellant-and-bipropellant-thrusters
#8
Kyun Ho Lee
In general, a space propulsion system has a crucial role in the normal mission operations of a spacecraft. Depending on the types and number of propellants, a monopropellant and a bipropellant thrusters are mostly utilized for low thrust liquid rocket engines. As the plume gas flow exhausted from these small thrusters expands freely in a vacuum space environment along all directions, adverse effects of the plume impingement onto the spacecraft surfaces can dramatically reduce the function and performance of a spacecraft...
2017: PloS One
https://www.readbyqxmd.com/read/28481218/propulsive-performance-of-an-under-actuated-robotic-ribbon-fin
#9
Hanlin Liu, Oscar Curet
Many aquatic animals propelled by elongated undulatory fins can perform complex maneuvers and swim with high efficiency at low speeds. In this type of swimming, one or multiple waves travel along the flexible fin that is composed of fin rays (for bony fish) interconnected with an elastic membrane. In this work, we explore the potential benefits or disadvantages of using passive fin motion based on the coupling of fluid-structure interaction and the elasto-mechanical responses of the undulatory fin. The motivation of this work is to understand how an under-actuated undulating fin can modify its active and passive fin motion to effectively control the hydrodynamic forces and propulsive efficiency...
May 8, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28474606/asymmetries-in-wing-inertial-and-aerodynamic-torques-contribute-to-steering-in-flying-insects
#10
Mark Jankauski, Thomas Daniel, I Shen
Maneuvering in both natural and artificial miniature flying systems is assumed to be dominated by aerodynamic phenomena. To explore this, we develop a flapping wing model integrating aero and inertial dynamics. The model is applied to an elliptical wing similar to the forewing of the Hawkmoth Manduca sexta and realistic kinematics are prescribed. We explore critically the stroke deviation phase, as it relates to firing latency in airborne insect steering muscles which has been correlated to various aerial maneuvers...
May 5, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28473863/role-of-acupoint-area-collagen-fibers-in-anti-inflammation-of-acupuncture-lifting-and-thrusting-manipulation
#11
Fan Wang, Guang-Wei Cui, Le Kuai, Jian-Min Xu, Ting-Ting Zhang, Huai-Jin Cheng, Hong-Sheng Dong, Gui-Rong Dong
The role of the acupoint area collagen fibers in the efficacy of acupuncture lifting and thrusting (L&T) manipulation will be explored in this paper. 30 male NZW rabbits were randomly divided into 6 groups: sham operation group (Group N), model group (Group M), acupuncture without manipulation group (Group W), acupuncture L&T manipulation group (Group A), collagenase pretreatment group (Group JM), and collagenase pretreatment + acupuncture L&T manipulation group (Group JA). The bacterial endotoxin was used to generate the rabbit fever models...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28471718/mechanical-power-thrust-power-and-propelling-efficiency-relationships-with-elite-sprint-swimming-performance
#12
Giorgio Gatta, Matteo Cortesi, Ian Swaine, Paola Zamparo
The purpose of this study was to explore the relationships between mechanical power, thrust power, propelling efficiency and sprint performance in elite swimmers. Mechanical power was measured in 12 elite sprint male swimmers: (1) in the laboratory, by using a whole-body swimming ergometer (W'TOT) and (2) in the pool, by measuring full tethered swimming force (FT) and maximal swimming velocity (Vmax): W'T = FT · Vmax. Propelling efficiency (ηP) was estimated based on the "paddle wheel model" at Vmax. Vmax was 2...
May 4, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28462826/notched-k-wire-for-low-thermal-damage-bone-drilling
#13
Yao Liu, Barry Belmont, Yiwen Wang, Bruce Tai, James Holmes, Albert Shih
The Kirschner wire (K-wire) is a common bone drilling tool in orthopedic surgery to affix fractured bone. Significant heat is produced due to both the cutting and the friction between the K-wire and the bone debris during drilling. Such heat can result in high temperatures, leading to osteonecrosis and other secondary injuries. To reduce thermal injury and other high-temperature associated complications, a new K-wire design with three notches along the three-plane trocar tip fabricated using a thin micro-saw tool is studied...
April 24, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28461199/new-structural-formats-of-therapeutic-antibodies-for-rheumatology
#14
Christophe Dumet, Jérémy Pottier, Valérie Gouilleux, Hervé Watier
Pharmaceutical companies strive continuously to develop better medications in order to remain competitive. In the arena of monoclonal antibodies and related biologics (fusion proteins containing an IgG Fc fragment), the thrust is not only toward identifying new targets, but also toward developing new molecular formats. Here, new-generation antibodies used to treat rheumatic diseases are discussed, with emphasis on relations linking structure to pharmacological effects and on the improvements expected from the new formats...
April 28, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28460375/experimental-evidence-that-thrust-earthquake-ruptures-might-open-faults
#15
Vahe Gabuchian, Ares J Rosakis, Harsha S Bhat, Raúl Madariaga, Hiroo Kanamori
Many of Earth's great earthquakes occur on thrust faults. These earthquakes predominantly occur within subduction zones, such as the 2011 moment magnitude 9.0 eathquake in Tohoku-Oki, Japan, or along large collision zones, such as the 1999 moment magnitude 7.7 earthquake in Chi-Chi, Taiwan. Notably, these two earthquakes had a maximum slip that was very close to the surface. This contributed to the destructive tsunami that occurred during the Tohoku-Oki event and to the large amount of structural damage caused by the Chi-Chi event...
May 1, 2017: Nature
https://www.readbyqxmd.com/read/28458111/implementing-industrial-academic-partnerships-to-advance-bioenergy-research-the-energy-biosciences-institute
#16
REVIEW
Heather Youngs, Chris Somerville
The Energy Bioscience Institute (EBI) is an example of an ambitious academic-industry collaboration. We present a summary of how the EBI was organized during the first eight years and examples of several major research thrusts within the Institute to develop renewable biodiesel, jet fuel and lubricants from carbohydrates. In particular, we describe how the multidisciplinary nature and management structure of the organization led to hybrid approaches in which bioconversions and chemical synthesis were combined to develop new products...
April 27, 2017: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/28456600/beliefs-in-the-population-about-cracking-sounds-produced-during-spinal-manipulation
#17
Christophe Demoulin, Damien Baeri, Geoffrey Toussaint, Barbara Cagnie, Axel Beernaert, Jean-François Kaux, Marc Vanderthommen
OBJECTIVES: To examine beliefs about cracking sounds heard during high-velocity low-amplitude (HVLA) thrust spinal manipulation in individuals with and without personal experience of this technique. METHODS: We included 100 individuals. Among them, 60 had no history of spinal manipulation, including 40 who were asymptomatic with or without a past history of spinal pain and 20 who had nonspecific spinal pain. The remaining 40 patients had a history of spinal manipulation; among them, 20 were asymptomatic and 20 had spinal pain...
April 26, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28456256/development-of-a-high-frequency-and-large-stroke-fatigue-testing-system-for-rubber
#18
Gang Chen, Hao Wu, Jianwen Gao, Qiang Lin
The limited capabilities of current fatigue testing machines have resulted in studies on the fatigue behavior of rubber under large-displacement amplitude and high frequency being very sparse. In this study, a fatigue testing system that can carry out large-displacement amplitude and high-frequency fatigue tests on rubber was developed using a moving magnet voice coil motor (MMVCM) actuator, with finite element analysis applied to analyze the thrust of the MMVCM actuator. The results of a series of cyclic tension tests conducted on vulcanized natural rubber specimens using the developed fatigue testing system verify that it has high precision, low noise, large-stroke, and high-frequency characteristics...
April 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28456244/inline-screw-feeding-vacuum-arc-thruster
#19
Igal Kronhaus, Matteo Laterza, Yonatan Maor
A new type of micropropulsion device for nanosatellite applications is presented-the inline-screw-feeding vacuum-arc thruster (ISF-VAT). This thruster couples a conventional "triggerless" ignition geometry with a feeding mechanism that maintains a steady state discharge performance. The feeding mechanism implements a screw action on a central cathode rod. At a predetermined rate, a complete and uniform erosion of the cathodes tip is obtained as well as "healing" of the insulator coating. The inline feeding of the cathode forces the arc to emerge on the tip of the cathode, flush with the exit plane of the anode...
April 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28430671/elevated-production-of-nociceptive-cc-chemokines-and-se-selectin-in-patients-with-low-back-pain-and-the-effects-of-spinal-manipulation-a-non-randomized-clinical-trial
#20
Julita A Teodorczyk-Injeyan, Marion McGregor, John J Triano, H Stephen Injeyan
BACKGROUND: The involvement of inflammatory components in the pathophysiology of low back pain is poorly understood. It has been suggested that spinal manipulative therapy (SMT) may exert anti-inflammatory effects. PURPOSE: To determine the involvement of inflammation-associated chemokines (CC series) in the pathogenesis of non-specific low back pain and to evaluate the effect of SMT on that process. METHODS: Patients presenting with non-radicular, non-specific low back pain (minimum pain score 3 on 10 point visual analogue scale, VAS) were recruited according to stringent inclusion criteria...
April 19, 2017: Clinical Journal of Pain
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