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https://www.readbyqxmd.com/read/29107251/progressive-metabolic-impairment-underlies-the-novel-nematicidal-action-of-fluensulfone-on-the-potato-cyst-nematode-globodera-pallida
#1
James Kearn, Catherine Lilley, Peter Urwin, Vincent O'Connor, Lindy Holden-Dye
BACKGROUND: Fluensulfone is a new nematicide with an excellent profile of selective toxicity against plant parasitic nematodes. Here, its effects on the physiology and biochemistry of the potato cyst nematode Globodera pallida have been investigated and comparisons made with its effect on the life-span of the free-living nematode Caenorhabditis elegans to provide insight into its mode of action and its selective toxicity. RESULTS: Fluensulfone exerts acute effects (≤1h; ≥100μM) on stylet thrusting and motility of hatched second stage G...
October 2017: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/29105475/-dynamic-changes-of-ultrasonographic-images-of-zusanli-st-36-region-during-deqi-of-acupuncture-needle-stimulation
#2
Xiao-Ming Wu, Xiang Mao, Xi Zhou, Zhao-Peng Xie, Yuan-Yi Zheng, Jian-Zhong Xu, Zhu-Xing Wang
OBJECTIVE: To observe the dynamic changes of ultrosonographic images of Zusanli (ST 36) area during Deqi after inserting acupuncture needles, so as to provide objective evidence for clinical Deqi. METHODS: Sixty healthy volunteers (30 men and 30 women) were recruited in the present study. The subjects were asked to take a supine position on a test-bed, sterilized disposable filiform needles were perpendicularly inserted into bilateral ST 36 till Deqi (without lifting, thrusting and twirling), when, high-resolution ultrasound scanning was conducted over the regional skeletal muscles by using a radio-frequency (5-12 MHz) coil probe (Philips IU Elite Ultrasound Diagnostic Instrument) after smearing a layer of gel at the skin of ST 36...
October 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29097308/analysis-of-natural-product-regulation-of-opioid-receptors-in-the-treatment-of-human-disease
#3
REVIEW
S Badal, S Turfus, R Rajnarayanan, C Wilson-Clarke, S L Sandiford
Opioid receptors (ORs), μOR, δOR, κOR and ORL1 mediate numerous signaling cascades, most importantly, through the modulation of ion channels. Research demonstrates the role of OR mediated signal transduction in treating pain, cancer, neurodegenerative disorders and cardiac insults. Yet, the primary application of drugs that modulate ORs is analgesia. Current opioids like morphine that are mainly μOR orthosteric agonists attract many undesirable side-effects (constipation, urinary retention, respiratory depression and hypotension) and the existing modus operandi against these is the inclusion of a μOR antagonist (for example...
October 30, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29096352/vaginal-cuff-dehiscence-and-evisceration-11-years-after-a-radical-hysterectomy-a-case-report
#4
Yacine Ben Safta, Montassar Ghalleb, Aymen Baccari, Ghassen Hamdi El Kebir, Sami Daldoul, Sofiene Sayari, Mounir Ben Moussa
INTRODUCTION: Vaginal cuff dehiscence (VCD) and evisceration (VCDE) are rare but rather serious complications of hysterectomy procedures. We aimed to report a case of VCDE happening eleven years after the initial surgery and review a treatment protocol of this rare complication. CASE: A 68 years old Tunisian female patient In 2004, the patient underwent concomitant chemoradiation followed by total abdominal radical hysterectomy for a squamous cell carcinoma of the cervix...
October 28, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29096189/development-of-a-bi-directional-standing-wave-linear-piezoelectric-actuator-with-four-driving-feet
#5
Yingxiang Liu, Shengjun Shi, Chunhong Li, Weishan Chen, Liang Wang, Junkao Liu
A bi-directional standing wave linear piezoelectric ultrasonic actuator with four driving feet is proposed in this work. Two sandwich type transducers operated in longitudinal-bending hybrid modes are set parallelly. The working mode of the transducer is not simple hybrid vibrations of a longitudinal one and a bending one, but a special coupling vibration mode contained both longitudinal and bending components. Two transducers with the same structure and unsymmetrical boundary conditions are set parallelly to accomplish the bi-directional driving: the first transducer can push the runner forward, while the other one produces the backward driving...
October 26, 2017: Ultrasonics
https://www.readbyqxmd.com/read/29089237/the-effects-of-cutting-parameters-on-cutting-forces-and-heat-generation-when-drilling-animal-bone-and-biomechanical-test-materials
#6
Akos Cseke, Robert Heinemann
The research presented in this paper investigated the effects of spindle speed and feed rate on the resultant cutting forces (thrust force and torque) and temperatures while drilling SawBones(®) biomechanical test materials and cadaveric cortical bone (bovine and porcine femur) specimens. It also investigated cortical bone anisotropy on the cutting forces, when drilling in axial and radial directions. The cutting forces are only affected by the feed rate, whereas the cutting temperature in contrast is affected by both spindle speed and feed rate...
October 28, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/29072020/-xingnao-kaiqiao-needling-stimulation-promotes-resuscitation-of-general-anesthesia-patients-undergoing-anodynia-gastrointestinal-endoscopy
#7
Yan Zhang, Zhe-Hua Li, A-Qin Xiong
OBJECTIVE: To observe the effect of "Xingnao Kaiqiao" needling on the recovery of general anesthesia in mid-aged and elderly patients undergoing painless gastrointestinal endoscopy. METHODS: A total of 140 patients were randomly divided into control and treatment groups, with 70 cases in each group. After termination of the endoscopy, patients of the treatment group received acupuncture stimulation of Neiguan (PC 6), Shuigou (GV 26) and Sanyinjiao (SP 6) with sterilized disposable filiform needles which were manipulated with twirling-reducing method for 3 min in PC 6, with lifting-thrusting reinforcing method in SP 6, and with bird-peck needling in GV 26...
August 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29064664/nitrogenase-cofactor-assembly-an-elemental-inventory
#8
Nathaniel S Sickerman, Markus W Ribbe, Yilin Hu
Nitrogenase is known for its remarkable ability to catalyze the reduction of N2 to NH3, and C1 substrates to short-chain hydrocarbon products, under ambient conditions. The best-studied Mo-nitrogenase utilizes a complex metallocofactor as the site of substrate binding and reduction. Designated the M-cluster, this [MoFe7S9C(R-homocitrate)] cluster can be viewed as [MoFe3S3] and [Fe4S3] subclusters bridged by three μ2-sulfides and one μ6-interstitial carbide, with its Mo end further coordinated by an R-homocitrate moiety...
October 24, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29056452/spike-burst-coding-of-translatory-optic-flow-and-depth-from-motion-in-the-fly-visual-system
#9
Kit D Longden, Martina Wicklein, Ben J Hardcastle, Stephen J Huston, Holger G Krapp
Many animals use the visual motion generated by traveling straight-the translatory optic flow-to successfully navigate obstacles: near objects appear larger and to move more quickly than distant objects. Flies are expert at navigating cluttered environments, and while their visual processing of rotatory optic flow is understood in exquisite detail, how they process translatory optic flow remains a mystery. We present novel cell types that have local motion receptive fields matched to translation self-motion, the vertical translation (VT) cells...
November 6, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29055709/thioredoxin-reductase-from-the-bovine-filarial-parasite-setaria-cervi-studies-on-its-localization-and-optimization-of-the-extraction
#10
Nikhilesh Joardar, Suprabhat Mukherjee, Santi P Sinha Babu
Exploration of novel drug targets has been the major thrust area in filarial research. In this regard, identification and characterization of oxidative enzymes that play pivotal role in the survival of filarial parasite inside host are of immense importance. In this study, we are reporting the presence of an important redox regulatory enzyme, thioredoxin reductase (TrxR) in the bovine filarial parasite Setaria cervi. TrxR was found to be exists throughout the developmental stages viz. oocyte, microfilaria and adult of the parasite...
October 18, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29051869/case-of-acute-concomitant-rupture-of-anterior-cruciate-ligament-and-patellar-tendon-of-knee-surgical-decision-making-and-outcome
#11
Jithin Orville Lobo, Joe Joseph Cherian, Arnav Sahu
INTRODUCTION: Acute concomitant rupture of both anterior cruciate ligament (ACL) and patellar tendon is a rare injury. The diagnosis of either of the injuries may be missed on clinical examination in the emergency room. A high index of suspicion is necessary when active extension is absent, and necessary investigations like ultrasound or magnetic resonance imaging (MRI) should be done to confirm the diagnosis. There are no fixed treatment protocols in these injuries. The options include immediate repair of patellar tendon with either simultaneous or delayed reconstruction of ACL...
May 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29044053/fungal-keratitis-the-aravind-experience
#12
REVIEW
Venkatesh N Prajna, Lalitha Prajna, Srinivasan Muthiah
Research becomes very significant and meaningful when it addresses a significant public health problem of a region. Fungal keratitis is a serious problem affecting the agrarian poor and hence requires attention from public health specialists. The approach to a public health issue should focus not only on treatment but also prevention or at least show a significant thrust to reduce the morbidity of the problem. At our institution, we have developed a special interest in fungal keratitis and tried to study it in a multitude of aspects...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29042703/modification-of-dentofacial-growth-associated-with-goldenhar-syndrome
#13
Ei Ei Hsu Hlaing, Yoshihito Ishihara, Chikako Hara, Hiroshi Kamioka
The rare developmental defect, Goldenhar syndrome is characterized by complex craniofacial and dentofacial anomalies. Here we describe the successful orthodontic treatment of a 5-year-old Japanese Goldenhar syndrome patient with mild facial asymmetry, right microtia, right-side hearing loss, and tongue-thrusting by a modification of dentofacial growth using a non-surgical orthopedic treatment approach. Improvement of the vertical discrepancies on the affected side and canted occlusal plane as well as mandibular deviation were achieved with a functional orthopaedic approach...
October 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29042653/silica-precipitation-potentially-controls-earthquake-recurrence-in-seismogenic-zones
#14
Hanae Saishu, Atsushi Okamoto, Makoto Otsubo
Silica precipitation is assumed to play a significant role in post-earthquake recovery of the mechanical and hydrological properties of seismogenic zones. However, the relationship between the widespread quartz veins around seismogenic zones and earthquake recurrence is poorly understood. Here we propose a novel model of quartz vein formation associated with fluid advection from host rocks and silica precipitation in a crack, in order to quantify the timescale of crack sealing. When applied to sets of extensional quartz veins around the Nobeoka Thrust of SW Japan, an ancient seismogenic splay fault, our model indicates that a fluid pressure drop of 10-25 MPa facilitates the formation of typical extensional quartz veins over a period of 6...
October 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29040795/case-presentation-of-anti-nmda-receptor-encephalitis-in-a-4-year-old-boy
#15
Daniel A Gbadero, Emmanuel O Adegbite, Jean-Baptist LePichon, Tina M Slusher
We report a case of a 4-year-old boy from Oyo, Nigeria, presenting with prolonged seizures and coma with the subsequent development of oro-lingual-facial dyskinesia with frequent tongue thrusting, dysconjugate gaze and choreoathetoid movements of the limbs because of autoimmune encephalitis consistent with anti-N-methyl-D-aspartate (anti-NMDAR) encephalitis.
October 6, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29037635/the-immediate-effect-of-talocrural-joint-manipulation-on-functional-performance-of-15-40-years-old-athletes-with-chronic-ankle-instability-a-double-blind-randomized-clinical-trial
#16
Fahimeh Kamali, Ehsan Sinaei, Sara Bahadorian
OBJECTIVE: To evaluate the immediate effect of talocrural joint manipulation (TCJM) on functional performance of athletes with chronic ankle instability (CAI). PARTICIPANTS: Forty athletes (18males, 22females) with CAI divided into TCJM group (n = 20) and sham manipulation group (n = 20). INTERVENTION: TCJM was performed as a quick thrust on the involved talus, in the posterior direction. Sham manipulation was maintaining the same position, without any thrust...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29021978/global-health-teaching-in-india-a-curricular-landscape
#17
REVIEW
Sanghamitra Pati, Rajeshwari Sinha, Meely Panda, Sandipana Pati, Anjali Sharma, Sanjay Zodpey
Today, health has transcended national boundaries and become more multifaceted. Global health has evolved as a new paradigm and is recently being identified as a thrust area now in India. Despite an existing need for a standardized global health curriculum, there is little information available on its education and curriculum in medical and health education space. In the Indian context, we are yet to have a fuller picture of the current status, including, content, structure, selection, teaching methods of global health, and how students are evaluated in India...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29021654/use-of-a-stopwatch-to-measure-ejaculatory-latency-may-not-be-accurate-among-indian-patients
#18
Gajanan Shripad Bhat, Anuradha Shastry
INTRODUCTION: Although the use of a stopwatch is recommended to record intravaginal ejaculatory latency time (IELT) for premature ejaculation, there is no Indian literature which assesses the reliability of this method among our patients. Hence, we assessed the accuracy of stopwatch-measured IELT and compared it with other methods such as number of thrusts and self-assessed IELT in an Indian context. METHODS: Between January 2015 and December 2015, couples with premature ejaculation (PE) confirmed with the Premature Ejaculation Diagnostic Tool were enrolled in this study...
October 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28994350/the-validity-of-the-mmpi-2-mmpi-2-rf-symptom-validity-scale-fbs-fbs-r-is-established-reply-to-nichols-2017
#19
Glenn J Larrabee, Kevin J Bianchini, Kyle B Boone, Martin L Rohling
We reply to Nichols' (2017) critique of our commentary on the MMPI-2/MMPI-2-RF Symptom Validity Scale (FBS/FBS-r) as a measure of symptom exaggeration versus a measure of litigation response syndrome (LRS). Nichols claims that we misrepresented the thrust of the original paper he co-authored with Gass; namely, that they did not represent that the FBS/FBS-r were measures of LRS but rather, intended to convey that the FBS/RBS-r were indeterminate as to whether the scales measured LRS or measured symptom exaggeration...
November 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28990459/multi-objective-performance-investigation-of-orthopaedic-bone-drilling-using-taguchi-membership-function
#20
Gurmeet Singh, Vivek Jain, Dheeraj Gupta
Orthopaedic bone drilling attacks the surrounded bone cells and tissues in terms of thermal and mechanical in such a way that these cells can get damaged permanently. This damage to the surrounding of drill point upsurges the rehabilitation time of injury and in some cases leads to the failure of the bone screw joint. This study is based on the optimization of multiple response characteristics to minimize the damage during the bone drilling. All real-life problems, including bone drilling, require the multiple response optimization for getting a combined optimization result for all countable response characteristics...
October 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
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