keyword
MENU ▼
Read by QxMD icon Read
search

graziano Onder

keyword
https://www.readbyqxmd.com/read/29778885/effects-of-hyperpolypharmacy-and-potentially-inappropriate-medications-pims-on-functional-decline-in-older-patients-discharged-from-acute-care-hospitals
#1
Paolo Fabbietti, Carmelinda Ruggiero, Federica Sganga, Sergio Fusco, Federica Mammarella, Norma Barbini, Laura Cassetta, Graziano Onder, Andrea Corsonello, Fabrizia Lattanzio, Mirko Di Rosa
AIM: To comparatively investigate the effects of hyperpolypharmacy and potentially inappropriate medications (PIMs) on functional decline in older patients after hospital discharge. METHODS: Our series consisted of 733 patients aged ≥65 consecutively enrolled in a multicenter observational longitudinal study. PIMs were defined on the basis of updated versions of Beers and STOPP criteria. The occurrence of functional decline was defined as the loss of independency in at least 1 basic activity of daily living (BADL) from discharge through 3-month follow-up visit...
May 16, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29726918/frailty-and-multimorbidity-a-systematic-review-and-meta-analysis
#2
Davide L Vetrano, Katie Palmer, Alessandra Marengoni, Emanuele Marzetti, Fabrizia Lattanzio, Regina Roller-Wirnsberger, Luz Lopez Samaniego, Leocadio Rodríguez-Mañas, Roberto Bernabei, Graziano Onder
Background: Multimorbidity and frailty are complex syndromes characteristics of ageing. We reviewed the literature, and provided pooled estimations of any evidence regarding a) the coexistence of frailty and multimorbidity, and b) their association. Methods: We searched PubMed and Web of Science for relevant articles up to September 2017. Pooled estimates were obtained through random effect models and Mantel-Haenszel weighting. Homogeneity (I2), risk of bias and publication bias were assessed...
May 3, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29689719/the-behavioral-and-psychological-symptoms-of-dementia-in-down-syndrome-bpsd-ds-scale-comprehensive-assessment-of-psychopathology-in-down-syndrome
#3
Alain D Dekker, Silvia Sacco, Angelo Carfi, Bessy Benejam, Yannick Vermeiren, Gonny Beugelsdijk, Mieke Schippers, Lyanne Hassefras, José Eleveld, Sharina Grefelman, Roelie Fopma, Monique Bomer-Veenboer, Mariángeles Boti, G Danielle E Oosterling, Esther Scholten, Marleen Tollenaere, Laura Checkley, André Strydom, Gert Van Goethem, Graziano Onder, Rafael Blesa, Christine Zu Eulenburg, Antonia M W Coppus, Anne-Sophie Rebillat, Juan Fortea, Peter P De Deyn
People with Down syndrome (DS) are prone to develop Alzheimer's disease (AD). Behavioral and psychological symptoms of dementia (BPSD) are core features, but have not been comprehensively evaluated in DS. In a European multidisciplinary study, the novel Behavioral and Psychological Symptoms of Dementia in Down Syndrome (BPSD-DS) scale was developed to identify frequency and severity of behavioral changes taking account of life-long characteristic behavior. 83 behavioral items in 12 clinically defined sections were evaluated...
April 16, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29549539/a-review-of-telomere-length-in-sarcopenia-and-frailty
#4
REVIEW
Maria Lorenzi, Stefano Bonassi, Teresa Lorenzi, Silvia Giovannini, Roberto Bernabei, Graziano Onder
Sarcopenia and frailty are associated with several important health-related adverse events, including disability, loss of independence, institutionalization and mortality. Sarcopenia can be considered a biological substrate of frailty, and the prevalence of both these conditions progressively increases with age. Telomeres are nucleoprotein structures located at the end of linear chromosomes and implicated in cellular ageing, shorten with age, and are associated with various age-related diseases. In addition, telomere length (TL) is widely considered a molecular/cellular hallmark of the ageing process...
March 16, 2018: Biogerontology
https://www.readbyqxmd.com/read/29526651/accounting-for-frailty-when-treating-chronic-diseases
#5
REVIEW
Graziano Onder, Davide L Vetrano, Alessandra Marengoni, J Simon Bell, Kristina Johnell, Katie Palmer
Chronic diseases are considered to be major determinants of frailty and it could be hypothesized that their treatment may counteract the development of frailty. However, the hypothesis that intensive treatment of chronic diseases might reduce the progression of frailty is poorly supported by existing studies. In contrast, some evidence suggests that intensive treatment of chronic diseases may increase negative health outcomes in frail older adults. In particular, if treatment of symptoms related to chronic diseases (i...
March 8, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29509768/trajectories-of-functional-decline-in-older-adults-with-neuropsychiatric-and-cardiovascular-multimorbidity-a-swedish-cohort-study
#6
Davide L Vetrano, Debora Rizzuto, Amaia Calderón-Larrañaga, Graziano Onder, Anna-Karin Welmer, Roberto Bernabei, Alessandra Marengoni, Laura Fratiglioni
BACKGROUND: Functional decline is a strong health determinant in older adults, and chronic diseases play a major role in this age-related phenomenon. In this study, we explored possible clinical pathways underlying functional heterogeneity in older adults by quantifying the impact of cardiovascular (CV) and neuropsychiatric (NP) chronic diseases and their co-occurrence on trajectories of functional decline. METHODS AND FINDINGS: We studied 2,385 people ≥60 years (range 60-101 years) participating in the Swedish National study of Aging and Care in Kungsholmen (SNAC-K)...
March 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29508369/development-and-application-of-the-gheop-3-s-tool-addendum-on-potentially-inappropriate-prescribing-pip-of-renally-excreted-active-drugs-reads-in-older-adults-with-polypharmacy
#7
Abdul Aziz Al Wazzan, Eline Tommelein, Katrien Foubert, Stefano Bonassi, Graziano Onder, Annemie Somers, Mirko Petrovic, Koen Boussery
BACKGROUND: Renal function progressively worsens with age. Potentially inappropriate prescribing (PIP) of renally excreted active drugs (READs) is common in older adults, leading to an increased rate of iatrogenic illness. The Ghent Older People's Prescription community Pharmacy Screening (GheOP3 S-) tool is an effective, explicit instrument that was developed for community pharmacists (CPs) to detect PIP. So far, this tool does not assess PIP of the frequently used READs in older patients with renal impairment...
April 2018: Drugs & Aging
https://www.readbyqxmd.com/read/29477493/the-relationship-between-copd-and-frailty-a-systematic-review-and-meta-analysis-of-observational-studies
#8
Alessandra Marengoni, Davide L Vetrano, Ester Manes-Gravina, Roberto Bernabei, Graziano Onder, Katie Palmer
BACKGROUND: Frailty is common in seniors and is characterized by diminished physiological reserves and increased vulnerability to stressors. Frailty can change the prognosis and treatment approach of several chronic diseases, including COPD. The association between frailty and COPD has never been systematically reviewed. OBJECTIVES: The goal of this study was to conduct a systematic review and meta-analysis assessing the association of COPD with frailty and pre-frailty...
March 1, 2018: Chest
https://www.readbyqxmd.com/read/29476480/educational-strategies-to-train-health-care-professionals-across-the-education-continuum-on-the-process-of-frailty-prevention-and-frailty-management-a-systematic-review
#9
REVIEW
Thomas Windhaber, Maria Lamprini Koula, Evangelia Ntzani, Alexandra Velivasi, Evangelos Rizos, Michail Theofilos Doumas, Evangelos Elias Pappas, Graziano Onder, Davide Liborio Vetrano, Angel Roudriguez Laso, Leocadio Roudriguez Manjas, Maddalena Illario, Regina Elisabeth Roller-Wirnsberger
BACKGROUND: In addition to the normal process of ageing, frailty, defined as a geriatric syndrome, is becoming more prevalent. Around 10% of people over 65 years and 25-50% of those aged over 85 years are frail. Frail elderly are more vulnerable to external stressors and have an increased risk of adverse health outcomes. To tackle these challenges, European Union (EU) member states need to develop a health work force capable of the right skills mix. A goal-centred education and training of professionals is crucial for effective and efficient health care delivery for Europe's greying population...
February 23, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29472049/comprehensive-geriatric-assessment-benefits-and-limitations
#10
EDITORIAL
Katie Palmer, Graziano Onder
No abstract text is available yet for this article.
February 19, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29411310/polypharmacy-in-home-care-in-europe-cross-sectional-data-from-the-ibenc-study
#11
Silvia Giovannini, Henriëtte G van der Roest, Angelo Carfì, Harriet Finne-Soveri, Vjenka Garms-Homolová, Anja Declercq, Pálmi V Jónsson, Hein van Hout, Davide L Vetrano, Ester Manes Gravina, Roberto Bernabei, Graziano Onder
BACKGROUND: Home care (HC) patients are characterized by a high level of complexity, which is reflected by the prevalence of multimorbidity and the correlated high drug consumption. This study assesses prevalence and factors associated with polypharmacy in a sample of HC patients in Europe. METHODS: We conducted a cross-sectional analysis on 1873 HC patients from six European countries participating in the Identifying best practices for care-dependent elderly by Benchmarking Costs and outcomes of community care (IBenC) project...
February 2018: Drugs & Aging
https://www.readbyqxmd.com/read/29396191/sarcopenia-in-parkinson-disease-comparison-of-different-criteria-and-association-with-disease-severity
#12
Davide L Vetrano, Maria S Pisciotta, Alice Laudisio, Maria R Lo Monaco, Graziano Onder, Vincenzo Brandi, Domenico Fusco, Beatrice Di Capua, Diego Ricciardi, Roberto Bernabei, Giuseppe Zuccalà
OBJECTIVES: In Parkinson disease (PD), sarcopenia may represent the common downstream pathway that from motor and nonmotor symptoms leads to the progressive loss of resilience, frailty, and disability. Here we (1) assessed the prevalence of sarcopenia in older adults with PD using 3 different criteria, testing their agreement, and (2) evaluated the association between PD severity and sarcopenia. DESIGN: Cross-sectional, observation study. SETTING: Geriatric day hospital...
January 30, 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29383397/nsaids-utilization-for-musculoskeletal-indications-in-elderly-patients-with-cerebro-cardiovascular-disease
#13
Giuseppe Roberto, Claudia Bartolini, Federico Rea, Graziano Onder, Cristiana Vitale, Gianluca Trifirò, Ursula Kirchmayer, Alessandro Chinellato, Ersilia Lucenteforte, Giovanni Corrao, Alessandro Mugelli, Francesco Lapi, Rosa Gini
OBJECTIVES: To describe NSAID utilization for musculoskeletal conditions in a large cohort of Italian elderly with cerebro/cardiovascular disease, a population in which NSAIDs should be generally avoided due to the prothrombotic potential. METHODS: Administrative data from five Italian geographic areas were analyzed. Patients aged ≥ 65 with a cerebro/cardiovascular event recorded between 2008 and 2011 (cohort entry) were selected. Prescription NSAIDs reimbursed for musculoskeletal conditions and dispensed during 1 year follow-up were retrieved to describe (i) prevalence of use, (ii) average amount of defined daily doses of NSAIDs claimed by users per day of follow-up, and (iii) distribution of the received daily dose (RDD) among patients with ≥ 2 dispensings...
May 2018: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29361432/research-priorities-for-optimizing-geriatric-pharmacotherapy-an-international-consensus
#14
Edwin C K Tan, Janet K Sluggett, Kristina Johnell, Graziano Onder, Monique Elseviers, Lucas Morin, Davide L Vetrano, Jonas W Wastesson, Johan Fastbom, Heidi Taipale, Antti Tanskanen, J Simon Bell
Medication management is becoming increasingly challenging for older people, and there is limited evidence to guide medication prescribing and administration for people with multimorbidity, frailty, or at the end of life. Currently, there is a lack of clear research priorities in the field of geriatric pharmacotherapy. To address this issue, international experts from 5 research groups in geriatric pharmacotherapy and pharmacoepidemiology research were invited to attend the inaugural Optimizing Geriatric Pharmacotherapy through Pharmacoepidemiology Network workshop...
March 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29340963/interactions-between-drugs-and-geriatric-syndromes-in-nursing-home-and-home-care-results-from-shelter-and-ibenc-projects
#15
Graziano Onder, Silvia Giovannini, Federica Sganga, Ester Manes-Gravina, Eva Topinkova, Harriet Finne-Soveri, Vjenka Garms-Homolová, Anja Declercq, Henriëtte G van der Roest, Pálmi V Jónsson, Hein van Hout, Roberto Bernabei
AIM: Drugs may interact with geriatric syndromes by playing a role in the continuation, recurrence or worsening of these conditions. Aim of this study is to assess the prevalence of interactions between drugs and three common geriatric syndromes (delirium, falls and urinary incontinence) among older adults in nursing home and home care in Europe. METHODS: We performed a cross-sectional multicenter study among 4023 nursing home residents participating in the Services and Health for Elderly in Long-TERm care (Shelter) project and 1469 home care patients participating in the Identifying best practices for care-dependent elderly by Benchmarking Costs and outcomes of community care (IBenC) project...
January 16, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29315325/quality-indicators-for-community-care-for-older-people-a-systematic-review
#16
REVIEW
Karlijn J Joling, Liza van Eenoo, Davide L Vetrano, Veerle R Smaardijk, Anja Declercq, Graziano Onder, Hein P J van Hout, Henriëtte G van der Roest
BACKGROUND: Health care systems that succeed in preventing long term care and hospital admissions of frail older people may substantially save on their public spending. The key might be found in high-quality care in the community. Quality Indicators (QIs) of a sufficient methodological level are a prerequisite to monitor, compare, and improve care quality. This systematic review identified existing QIs for community care for older people and assessed their methodological quality. METHODS: Relevant studies were identified by searches in electronic reference databases and selected by two reviewers independently...
2018: PloS One
https://www.readbyqxmd.com/read/29199121/interventions-targeting-loneliness-and-social-isolation-among-the-older-people-an-update-systematic-review
#17
REVIEW
Andrea Poscia, Jovana Stojanovic, Daniele Ignazio La Milia, Mariusz Duplaga, Marcin Grysztar, Umberto Moscato, Graziano Onder, Agnese Collamati, Walter Ricciardi, Nicola Magnavita
This systematic review aims to summarize and update the current knowledge on the effectiveness of the existing interventions for alleviating loneliness and social isolation among older persons. A search of PubMed, ISI Web of science, SCOPUS, The Cochrane Library, and CINAHL databases was performed. The terminology combined all possible alternatives of the following keywords: social isolation, loneliness, old people, intervention and effectiveness. Eligible studies were published between January 2011 and February 2016 in English or Italian language and regarded the implementation of loneliness/social isolation interventions among the older generations...
February 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29169575/health-determinants-and-survival-in-nursing-home-residents-in-europe-results-from-the-shelter-study
#18
Davide L Vetrano, Agnese Collamati, Nicola Magnavita, Agnieszka Sowa, Eva Topinkova, Harriet Finne-Soveri, Henriëtte G van der Roest, Beata Tobiasz-Adamczyk, Silvia Giovannini, Walter Ricciardi, Roberto Bernabei, Graziano Onder, Andrea Poscia
OBJECTIVE: The care processes directed towards institutionalized older people needs to be tailored on goals and priorities that are relevant for this specific population. The aim of the present study was (a) to describe the distribution of selected health determinants in a sample of institutionalized older adults, and (b) to investigate the impact on survival of such measures. DESIGN: Multicentre longitudinal cohort-study. SETTING: 57 nursing homes (NH) in 7EU countries (Czech Republic, England, Finland, France, Germany, Italy, The Netherlands) and 1 non-EU country (Israel)...
January 2018: Maturitas
https://www.readbyqxmd.com/read/29114834/polypharmacy
#19
Graziano Onder, Alessandra Marengoni
No abstract text is available yet for this article.
November 7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29069321/influenza-and-pneumococcal-vaccination-in-older-adults-living-in-nursing-home-a-survival-analysis-on-the-shelter-study
#20
Andrea Poscia, Agnese Collamati, Angelo Carfì, Eva Topinkova, Tomas Richter, Michael Denkinger, Roberta Pastorino, Francesco Landi, Walter Ricciardi, Roberto Bernabei, Graziano Onder
Background: Influenza and pneumococcal vaccines have been proved to be effective and safe in preventing and controlling infection among elderly, reducing morbidity and mortality. However, some evidences raised health concerns related to these vaccinations. This study aims to identify prevalence and outcomes related to influenza and pneumococcal vaccinations in a large European population of frail old people living in nursing homes (NHs). Methods: We conducted a survival analysis of NH residents participating to the Services and Health for Elderly in Long-TERm project, a prospective cohort study collecting information on residents admitted to 57 NH in eight countries (Czech Republic, England, Finland, France, Germany, Italy, The Netherlands and Israel)...
December 1, 2017: European Journal of Public Health
keyword
keyword
78513
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"