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https://www.readbyqxmd.com/read/28728364/growth-rate-carcass-characteristics-and-meat-quality-of-growing-lambs-fed-buckwheat-or-maize-silage
#1
Gurhan Keles, Veli Kocaman, Ahmet Onder Ustundag, Asli Zungur, Mursel Ozdogan
Objective: This study evaluated inclusion of buckwheat silage to the diet of growing lambs in terms of meat quality as compared to maize silage. Methods: Buckwheat, rich in total phenols (TP, 33 g/kg dry matter (DM)) harvested at the end of the milk stage and ensiled in 40 kg plastic bags after wilting (294 g/kg silage DM). A total of 18 growing lambs were individually fed isonitrogenous and isoenergetic total mixed rations (TMR) for 75 d that either contains buckwheat or maize silage at DM proportions of 0...
June 27, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28723550/induced-pluripotent-stem-cell-derived-primitive-macrophages-provide-a-platform-for-modeling-tissue-resident-macrophage-differentiation-and-function
#2
Kazuyuki Takata, Tatsuya Kozaki, Christopher Zhe Wei Lee, Morgane Sonia Thion, Masayuki Otsuka, Shawn Lim, Kagistia Hana Utami, Kerem Fidan, Dong Shin Park, Benoit Malleret, Svetoslav Chakarov, Peter See, Donovan Low, Gillian Low, Marta Garcia-Miralles, Ruizhu Zeng, Jinqiu Zhang, Chi Ching Goh, Ahmet Gul, Sandra Hubert, Bernett Lee, Jinmiao Chen, Ivy Low, Nurhidaya Binte Shadan, Josephine Lum, Tay Seok Wei, Esther Mok, Shohei Kawanishi, Yoshihisa Kitamura, Anis Larbi, Michael Poidinger, Laurent Renia, Lai Guan Ng, Yochai Wolf, Steffen Jung, Tamer Önder, Evan Newell, Tara Huber, Eishi Ashihara, Sonia Garel, Mahmoud A Pouladi, Florent Ginhoux
Tissue macrophages arise during embryogenesis from yolk-sac (YS) progenitors that give rise to primitive YS macrophages. Until recently, it has been impossible to isolate or derive sufficient numbers of YS-derived macrophages for further study, but data now suggest that induced pluripotent stem cells (iPSCs) can be driven to undergo a process reminiscent of YS-hematopoiesis in vitro. We asked whether iPSC-derived primitive macrophages (iMacs) can terminally differentiate into specialized macrophages with the help of growth factors and organ-specific cues...
July 18, 2017: Immunity
https://www.readbyqxmd.com/read/28719569/stress-analysis-of-zygomatic-implants-on-the-augmented-maxillary-sinus-is-it-necessary-to-graft
#3
Süleyman Kaman, Fethi Atıl, Umut Tekin, Ozkan Ozgul, Mustafa Ercument Önder, Seda Yılmaz, Hamiyet Gungor, Ismail Doruk Kocyigit
PURPOSE: Zygomatic implants are becoming an ideal therapy with advanced implant-supported prosthetic treatment for the posterior atrophic maxilla. The purpose of this study is to examine the quantity and distribution of stress, which was caused by zygomatic implants placed using intrasinus method with or without augmentation to the atrophic posterior maxilla. MATERIALS & METHODS: In this study, 3-dimensional atrophic edentulous maxilla models with and without sinus augmentation are designed with computer-aided programs...
July 17, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28717533/prevalence-of-erectile-dysfunction-in-men-over-40-years-of-age-in-turkey-results-from-the-turkish-society-of-andrology-male-sexual-health-study-group
#4
Selahittin Çayan, Muammer Kendirci, Önder Yaman, Ramazan Aşçı, İrfan Orhan, Mustafa Faruk Usta, Oğuz Ekmekçioğlu, Ateş Kadıoğlu
OBJECTIVE: Previous study conducted by the Turkish Society of Andrology in 1999 reported the prevalence of erectile dysfunction (ED) as 69.2% in men of ≥40 years of age, using a single-item non-validated question. This rate seemed to be higher compared to the studies reported worldwide. So, there was a need to carry out another epidemiological study by using validated questionnaires. Our aim was to investigate ED prevalence, severity, and its correlates in men aged ≥40 years using validated tools...
June 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28717531/the-role-of-vitamin-d-supplementation-on-erectile-function
#5
REVIEW
Raidh A Talib, Kareim Khalafalla, Önder Cangüven
In the last few years growing evidence highlighted vitamin D (VD) deficiency is one of the several dynamics that associates with increased atherosclerotic cardiovascular (ASCV) diseases. ASCV diseases and erectile dysfunction (ED) share common risk factors such as diabetes mellitus, hypertension, smoking, hyperlipidemia, and a sedentary lifestyle. The aim of this review was to summarize current progress in VD research by focusing effect of low VD level on different body systems and erectile function. Here we examine research linking VD deficiency and ED and discuss how VD influences ED and its classic risk factors that also associate to increased ED risk...
June 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28711962/the-relation-between-hemoglobin-variability-and-carotid-intima-media-thickness-in-chronic-hemodialysis-patients
#6
Safa Ersen Ganidagli, Orcun Altunoren, Ertuğrul Erken, Ismet Onder Isık, Berivan Ganidagli, Necmi Eren, Yasemin Coskun Yavuz, Ozkan Gungor
PURPOSE: Hemoglobin variability is a common problem among hemodialysis patients. We have previously demonstrated an association between Hb variability and left ventricular mass index. In this study, we investigated a possible relation between Hb variability and carotid intima-media thickness (CIMT). METHODS: Twelve-month hemoglobin (Hb) values of 135 patients on maintenance hemodialysis were examined retrospectively. The range of 11-12 gr/dl was accepted as normal according to the KDOQI guidelines...
July 15, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28709801/lymphatic-endothelial-cells-control-initiation-of-lymph-node-organogenesis
#7
Lucas Onder, Urs Mörbe, Natalia Pikor, Mario Novkovic, Hung-Wei Cheng, Thomas Hehlgans, Klaus Pfeffer, Burkhard Becher, Ari Waisman, Thomas Rülicke, Jennifer Gommerman, Christopher G Mueller, Shinichiro Sawa, Elke Scandella, Burkhard Ludewig
Lymph nodes (LNs) are strategically situated throughout the body at junctures of the blood vascular and lymphatic systems to direct immune responses against antigens draining from peripheral tissues. The current paradigm describes LN development as a programmed process that is governed through the interaction between mesenchymal lymphoid tissue organizer (LTo) cells and hematopoietic lymphoid tissue inducer (LTi) cells. Using cell-type-specific ablation of key molecules involved in lymphoid organogenesis, we found that initiation of LN development is dependent on LTi-cell-mediated activation of lymphatic endothelial cells (LECs) and that engagement of mesenchymal stromal cells is a succeeding event...
July 18, 2017: Immunity
https://www.readbyqxmd.com/read/28705451/nasal-carbon-dioxide-used-as-needed-in-the-symptomatic-treatment-of-seasonal-allergic-rhinitis
#8
Thomas B Casale, Robert F Onder, Robert B Berkowitz, Phillip E Korenblat
BACKGROUND: Nasal, noninhaled carbon dioxide (CO2) was shown to be effective for the treatment of symptoms of seasonal allergic rhinitis (SAR) and perennial allergic rhinitis in single application studies. OBJECTIVE: To assess the efficacy of as-needed treatment with nasal, noninhaled CO2 in patients with SAR. METHODS: Fifty-six ragweed-allergic patients were enrolled at 3 sites in this study. After a 3- to 7-day run-in, 32 eligible patients who had an instantaneous total nasal symptom score of 8 or more out of a maximum of 12 in at least 2 SAR episodes per day were randomized to the CO2 group (n = 19) or to the placebo group (n = 13)...
July 11, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28702761/can-a-hand-radiograph-indicate-a-special-diagnosis-in-a-child-with-chronic-kidney-disease-questions
#9
Eren Soyaltın, Belde Kasap-Demir, Caner Alparslan, Seçil Arslansoyu-Çamlar, Elif Perihan Öncel, Özgür Kırbıyık, Demet Alaygut, Önder Yavaşcan, Gamze Türe, Fatma Mutlubaş
No abstract text is available yet for this article.
July 12, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28702003/reduced-mass-and-diversity-of-the-colonic-microbiome-in-patients-with-multiple-sclerosis-and-their-improvement-with-ketogenic-diet
#10
Alexander Swidsinski, Yvonne Dörffel, Vera Loening-Baucke, Christoph Gille, Önder Göktas, Anne Reißhauer, Jürgen Neuhaus, Karsten-Henrich Weylandt, Alexander Guschin, Markus Bock
Background: Colonic microbiome is thought to be involved in auto-immune multiple sclerosis (MS). Interactions between diet and the colonic microbiome in MS are unknown. Methods: We compared the composition of the colonic microbiota quantitatively in 25 MS patients and 14 healthy controls.Fluorescence in situ hybridization (FISH) with 162 ribosomal RNA derived bacterial FISH probes was used. Ten of the MS patients received a ketogenic diet for 6 months. Changes in concentrations of 35 numerically substantial bacterial groups were monitored at baseline and at 2, 12, and 23/24 weeks...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28695538/fgf9-y162c-mutation-alters-information-processing-and-social-memory-in-mice
#11
Lillian Garrett, Lore Becker, Jan Rozman, Oliver Puk, Tobias Stoeger, Ali Önder Yildirim, Alexander Bohla, Oliver Eickelberg, Wolfgang Hans, Cornelia Prehn, Jerzy Adamski, Thomas Klopstock, Ildikó Rácz, Andreas Zimmer, Martin Klingenspor, Helmut Fuchs, Valerie Gailus-Durner, Wolfgang Wurst, Martin Hrabě de Angelis, Jochen Graw, Sabine M Hölter
In neuropsychiatric diseases, such as major depression and anxiety, pathogenic vulnerability is partially dictated by a genetic predisposition. The search continues to define this genetic susceptibility and establish new genetic elements as potential therapeutic targets. The fibroblast growth factors (FGFs) could be interesting in this regard. This family of signaling molecules plays important roles in development while also functioning within the adult. This includes effects on aspects of brain function such as neurogenesis and synapse formation...
July 10, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28687726/propagation-based-phase-contrast-x-ray-imaging-at-a-compact-light-source
#12
Regine Gradl, Martin Dierolf, Lorenz Hehn, Benedikt Günther, Ali Önder Yildirim, Bernhard Gleich, Klaus Achterhold, Franz Pfeiffer, Kaye Susannah Morgan
We demonstrate the applicability of propagation-based X-ray phase-contrast imaging at a laser-assisted compact light source with known phantoms and the lungs and airways of a mouse. The Munich Compact Light Source provides a quasi-monochromatic beam with partial spatial coherence, and high flux relative to other non-synchrotron sources (up to 10(10) ph/s). In our study we observe significant edge-enhancement and quantitative phase-retrieval is successfully performed on the known phantom. Furthermore the images of a small animal show the potential for live bio-imaging research studies that capture biological function using short exposures...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28686945/trophic-transfer-of-134-cs-in-the-manila-clam-ruditapes-philippinarum
#13
Murat Belivermiş, Önder Kılıç, Narin Sezer, Gülşah Kalaycı, Marc Metian
Bioaccumulation of radiocaesium in many marine organisms occurs through complex trophic transfer mechanisms. The present study addresses the trophic transfer of (134)Cs in the widely distributed marine bivalve, the Manila clam Ruditapes philippinarum, by experimentally determining the assimilation efficiency (AE) and the specific role of food quality or diet on the AE in this marine invertebrate. Pulse-chase feeding experiments were carried out on this clam using the phytoplankton species Tetraselmis chuii, Phaeodactylum tricornutum and Isochrysis galbana...
July 4, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28685282/bone-mineral-density-in-adults-with-down-syndrome
#14
A Carfì, R Liperoti, D Fusco, S Giovannini, V Brandi, D L Vetrano, E Meloni, D Mascia, E R Villani, E Manes Gravina, R Bernabei, G Onder
This study analyzed data of bone mineral density (BMD) from a large cohort of adults with Down syndrome (DS). BMD was found to decrease with age more rapidly in these subjects than in the general population, exposing adults with DS to an increased risk of osteoporosis and bone fracture. INTRODUCTION: Down syndrome (DS) in adulthood presents with a high prevalence of osteoporosis. However, in DS, bone mineral density (BMD) can be underestimated due to short stature. Furthermore, the rate of age-related decline in BMD and its association with gender in DS has been rarely evaluated or compared with the general population...
July 6, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28681843/ballistic-superconductivity-in-semiconductor-nanowires
#15
Hao Zhang, Önder Gül, Sonia Conesa-Boj, Michał P Nowak, Michael Wimmer, Kun Zuo, Vincent Mourik, Folkert K de Vries, Jasper van Veen, Michiel W A de Moor, Jouri D S Bommer, David J van Woerkom, Diana Car, Sébastien R Plissard, Erik P A M Bakkers, Marina Quintero-Pérez, Maja C Cassidy, Sebastian Koelling, Srijit Goswami, Kenji Watanabe, Takashi Taniguchi, Leo P Kouwenhoven
Semiconductor nanowires have opened new research avenues in quantum transport owing to their confined geometry and electrostatic tunability. They have offered an exceptional testbed for superconductivity, leading to the realization of hybrid systems combining the macroscopic quantum properties of superconductors with the possibility to control charges down to a single electron. These advances brought semiconductor nanowires to the forefront of efforts to realize topological superconductivity and Majorana modes...
July 6, 2017: Nature Communications
https://www.readbyqxmd.com/read/28675448/mpges-1-inhibitor-reduces-human-vascular-tone-by-increasing-pgi2-a-safer-alternative-to-coxibs
#16
Gulsev Ozen, Ingrid Gomez, Armond Daci, Catherine Deschildre, Lilia Boubaya, Onder Teskin, B Sonmez Uydeş-Doğan, Per-Johan Jakobsson, Dan Longrois, Gokce Topal, Xavier Norel
BACKGROUND AND PURPOSE: The side effects of cyclooxygenase-2 (COX-2) inhibitors (COXIBs) on the cardiovascular system could be associated with a reduced prostaglandin (PG) I2 synthesis. Microsomal prostaglandin E synthase-1 (mPGES-1) catalyzes the formation of PGE2 from COX-derived PGH2 . This enzyme is induced under inflammatory conditions and constitutes an attractive target for novel anti-inflammatory drugs. However, it is not known whether mPGES-1 inhibitors could be devoid of cardiovascular side effects...
July 3, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28671464/correction-to-monodisperse-au-nanoparticles-for-selective-electrocatalytic-reduction-of-co2-to-co
#17
Wenlei Zhu, Ronald Michalsky, Önder Metin, Haifeng Lv, Shaojun Guo, Christopher Wright, Xiaolian Sun, Andrew A Peterson, Shouheng Sun
No abstract text is available yet for this article.
July 3, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28665621/observation-of-conductance-quantization-in-insb-nanowire-networks
#18
Elham M T Fadaly, Hao Zhang, Sonia Conesa-Boj, Diana Car, Önder Gül, Sébastien R Plissard, Roy L M Op Het Veld, Sebastian Kölling, Leo P Kouwenhoven, Erik P A M Bakkers
Majorana zero modes (MZMs) are prime candidates for robust topological quantum bits, holding a great promise for quantum computing. Semiconducting nanowires with strong spin orbit coupling offer a promising platform to harness one-dimensional electron transport for Majorana physics. Demonstrating the topological nature of MZMs relies on braiding, accomplished by moving MZMs around each other in a certain sequence. Most of the proposed Majorana braiding circuits require nanowire networks with minimal disorder...
July 14, 2017: Nano Letters
https://www.readbyqxmd.com/read/28661478/kdm2b-an-h3k36-specific-demethylase-regulates-apoptotic-response-of-gbm-cells-to-trail
#19
Ibrahim Cagri Kurt, Ilknur Sur, Ezgi Kaya, Ahmet Cingoz, Selena Kazancioglu, Zeynep Kahya, Omer Duhan Toparlak, Filiz Senbabaoglu, Zeynep Kaya, Ezgi Ozyerli, Sercin Karahüseyinoglu, Nathan A Lack, Zeynep H Gümüs, Tamer T Onder, Tugba Bagci-Onder
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively kill tumor cells. TRAIL resistance in cancers is associated with aberrant expression of the key components of the apoptotic program. However, how these components are regulated at the epigenetic level is not understood. In this study, we investigated novel epigenetic mechanisms regulating TRAIL response in glioblastoma multiforme (GBM) cells by a short-hairpin RNA loss-of-function screen. We interrogated 48 genes in DNA and histone modification pathways and identified KDM2B, an H3K36-specific demethylase, as a novel regulator of TRAIL response...
June 29, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28659053/posterior-hip-approach-yields-better-functional-results-vis-%C3%A3-vis-anterolateral-approach-in-total-hip-arthroplasty-for-patients-with-severe-hip-dysplasia-a-prospective-randomized-controlled-clinical-study
#20
Faruk Mehmet Çatma, Alper Öztürk, Serhan Ünlü, Önder Ersan, Murat Altay
OBJECTIVES: We aimed to compare functional outcomes of two common hip approaches for patients with severe hip dysplasia in total hip replacement (THR) surgery. MATERIALS AND METHODS: Seventy hips of 68 patients randomized into two groups with regard to hip approach as posterior (group I) and anterolateral (group II). All patients underwent THR surgery with femoral shortening osteotomy. The groups were compared for operation time, preoperative and 6 months after abductor muscle strengths (AMSs), gait disorders, union time of the osteotomied site and dislocation rates...
May 2017: Journal of Orthopaedic Surgery
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