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https://www.readbyqxmd.com/read/29689719/the-behavioral-and-psychological-symptoms-of-dementia-in-down-syndrome-bpsd-ds-scale-comprehensive-assessment-of-psychopathology-in-down-syndrome
#1
Alain D Dekker, Silvia Sacco, Angelo Carfi, Bessy Benejam, Yannick Vermeiren, Gonny Beugelsdijk, Mieke Schippers, Lyanne Hassefras, José Eleveld, Sharina Grefelman, Roelie Fopma, Monique Bomer-Veenboer, Mariángeles Boti, G Danielle E Oosterling, Esther Scholten, Marleen Tollenaere, Laura Checkley, André Strydom, Gert Van Goethem, Graziano Onder, Rafael Blesa, Christine Zu Eulenburg, Antonia M W Coppus, Anne-Sophie Rebillat, Juan Fortea, Peter P De Deyn
People with Down syndrome (DS) are prone to develop Alzheimer's disease (AD). Behavioral and psychological symptoms of dementia (BPSD) are core features, but have not been comprehensively evaluated in DS. In a European multidisciplinary study, the novel Behavioral and Psychological Symptoms of Dementia in Down Syndrome (BPSD-DS) scale was developed to identify frequency and severity of behavioral changes taking account of life-long characteristic behavior. 83 behavioral items in 12 clinically defined sections were evaluated...
April 16, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29688071/idiopathic-intracranial-hypertension-and-bariatric-surgery
#2
Halil Onder
No abstract text is available yet for this article.
April 24, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29685560/high-rates-of-psychiatric-disorders-and-below-normal-mental-capacity-associated-with-spastic-peroneal-flatfoot-a-new-relationship
#3
Önder İsmet Kılıçoğlu, Ahmet Salduz, Fevzi Birişik, Fuat Bilgili, Gökhan Polat, İlyas Kaya, Funda Süleyman, Murat Coşkun
Spastic peroneal flatfoot (SPFF) is a rare hindfoot pathology usually seen in the adolescent age group that is characterized by painful spasms in the peroneal muscles. We have clinically observed that patients with SPFF also have some behavioral and emotional difficulties and problems in their academic achievements. Because of these observations, we investigated the prevalence and patterns of psychiatric disorders and intellectual disability among young subjects with SPFF. Our cohort consisted of 16 patients with SPFF...
May 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29677016/skin-necrosis-on-the-face-and-scalp-due-to-sclerotherapy
#4
Didem D Rota, Funda Tamer, Meltem Onder, Fatma Gulru Erdogan, Dilsun Yildirim
No abstract text is available yet for this article.
April 19, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29674392/cholesterol-metabolism-promotes-b-cell-positioning-during-immune-pathogenesis-of-chronic-obstructive-pulmonary-disease
#5
Jie Jia, Thomas M Conlon, Rim Sj Sarker, Demet Taşdemir, Natalia F Smirnova, Barkha Srivastava, Stijn E Verleden, Gizem Güneş, Xiao Wu, Cornelia Prehn, Jiaqi Gao, Katharina Heinzelmann, Jutta Lintelmann, Martin Irmler, Stefan Pfeiffer, Michael Schloter, Ralf Zimmermann, Martin Hrabé de Angelis, Johannes Beckers, Jerzy Adamski, Hasan Bayram, Oliver Eickelberg, Ali Önder Yildirim
The development of chronic obstructive pulmonary disease (COPD) pathogenesis remains unclear, but emerging evidence supports a crucial role for inducible bronchus-associated lymphoid tissue (iBALT) in disease progression. Mechanisms underlying iBALT generation, particularly during chronic CS exposure, remain to be defined. Oxysterol metabolism of cholesterol is crucial to immune cell localization in secondary lymphoid tissue. Here, we demonstrate that oxysterols also critically regulate iBALT generation and the immune pathogenesis of COPD In both COPD patients and cigarette smoke (CS)-exposed mice, we identified significantly upregulated CH25H and CYP7B1 expression in airway epithelial cells, regulating CS-induced B-cell migration and iBALT formation...
April 19, 2018: EMBO Molecular Medicine
https://www.readbyqxmd.com/read/29658389/comparison-of-endoscopic-assisted-and-temporary-keratoprosthesis-assisted-vitrectomy-in-combat-ocular-trauma-experience-at-a-tertiary-eye-center-in-turkey
#6
Onder Ayyildiz, Ali Hakan Durukan
Objective This study was performed to compare the functional and anatomical results of endoscopic-assisted and temporary keratoprosthesis (TKP)-assisted vitrectomy in patients with combat ocular trauma (COT). Methods The medical records of 14 severely injured eyes of 12 patients who underwent endoscopy or TKP implantation in combination with vitreoretinal surgery from 2007 to 2015 were retrospectively evaluated. The patients' ocular history and functional and anatomic anterior and posterior segment results were analyzed...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29608471/impact-of-nasal-septal-surgery-on-sleep-quality-and-attention-deficit-hyperactivity-disorder
#7
Ildem Deveci, Serap Onder, Mehmet Surmeli, Samil Sahin, Betul Aktas Kipoglu, Burak Karabulut, Basak Caypinar Eser
OBJECTIVE: To evaluate the effect of nasal septal surgery on quality of life. METHODS: A total of 49 patients who underwent septoplasty and/or inferior turbinate radiofrequency operations for nasal septal deviation and inferior turbinate hypertrophy were prospectively enrolled in the study. All patients completed the adult attention-deficit/hyperactivity disorder scale (ADHD scale) and Pittsburgh sleep quality index (PSQI) before and after septoplasty. Acoustic rhinometric measurements were also recorded...
March 30, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29602577/does-multimorbidity-still-remain-a-matter-of-the-elderly-lithuanian-national-data-analysis
#8
E Jurevičienė, G Onder, Ž Visockienė, R Puronaitė, D Petrikonytė, U Gargalskaitė, V Kasiulevičius, R Navickas
INTRODUCTION: Multimorbidity - the coexistence of ≥2 chronic conditions in same individual is usually associated with older age. There is an increase in its prevalence at a much younger age, however with very limited research specifying that. OBJECTIVE: To identify age breaking points for the occurrence of multimorbidity. METHODS: The study included patients, who used any healthcare services between the 01/01/2012 and 30/06/2014. Patients were divided into two groups - with single chronic condition and with multimorbidity...
March 14, 2018: Health Policy
https://www.readbyqxmd.com/read/29578925/successful-management-of-a-rare-cause-of-hemolytic-uremic-syndrome-with-eculizumab-in-a-child
#9
Caner Alparslan, Önder Yavaşcan, Belde Kasap Demir, Bahriye Atmiş, Aysun Karabay Bayazit, Göksel Leblebisatan, Elif P Öncel, Demet Alaygut, Fatma Mutlubaş, Nejat Aksu
BACKGROUND: Hemolytic uremic syndrome (HUS) is characterized by microangiopathic hemolytic anemia, acute renal failure, and thrombocytopenia. It very rarely coexists with acute lymphoblastic leukemia (ALL) emerging before, simultaneously, or after the diagnosis has been made, and management of the patient may be difficult. CASE: We present the case of a 7-year-old boy who was diagnosed with HUS and initially managed by hemodialysis (HD). Thereafter, HUS progressed, and neurological findings developed...
March 23, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29576897/primary-conjunctival-tuberculosis
#10
Nilgün Solmaz, Feyza Önder, Nedime Demir, Özlem Altuntaş Aydın
A 12-year-old girl was referred to our clinic because of unilateral conjunctivitis not responding to treatment. In the left eye, lower bulbar and tarsal conjunctiva had a polypoidal appearance due to micronodules and there was a subconjunctival nodular mass in the inferior fornix. Systemic examination was unremarkable except for a left preauricular lymphadenopathy. Excision biopsy of the subconjunctival mass revealed a granulomatous inflammation with caseation necrosis, but acid-fast bacilli (AFB) was negative...
February 2018: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29576890/long-term-results-in-pediatric-developmental-cataract-surgery-with-primary-intraocular-lens-implantation
#11
Elif Demirkılınç Biler, Şeyda Yıldırım, Önder Üretmen, Süheyla Köse
Objectives: The aim of this study was to evaluate the outcomes of pediatric developmental cataract surgery with primary intraocular lens (IOL) implantation. Materials and Methods: Patients between 2 and 16 years old who underwent cataract surgery with primary IOL implantation were retrospectively evaluated. Age at time of surgery, pre- and postoperative best corrected visual acuities, postoperative ocular complications, and any accompanying ocular pathologies were obtained from the patients' charts...
February 2018: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29572727/should-we-rely-on-doppler-ultrasound-for-evaluation-of-testicular-solid-lesions
#12
Baris Esen, Muhiddin Önder Yaman, Sümer Baltacı
PURPOSE: Colour Doppler ultrasound (CDUS) is the main radiologic tool to evaluate scrotal masses and intratesticular-vascularised solid lesions are mostly considered malign lesions. Objective of this trial is determine ratio of benign lesions in patients with hypervascularised solid intratesticular lesions. MATERIAL AND METHOD: Patients who underwent radical orchiectomy due to hypervascularised intratesticular solid lesions detected in CDUS are evaluated retrospectively...
March 23, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29550063/design-of-a-completely-model-free-adaptive-control-in-the-presence-of-parametric-non-parametric-uncertainties-and-random-control-signal-delay
#13
Onder Tutsoy, Duygun Erol Barkana, Harun Tugal
In this paper, an adaptive controller is developed for discrete time linear systems that takes into account parametric uncertainty, internal-external non-parametric random uncertainties, and time varying control signal delay. Additionally, the proposed adaptive control is designed in such a way that it is utterly model free. Even though these properties are studied separately in the literature, they are not taken into account all together in adaptive control literature. The Q-function is used to estimate long-term performance of the proposed adaptive controller...
March 14, 2018: ISA Transactions
https://www.readbyqxmd.com/read/29549539/a-review-of-telomere-length-in-sarcopenia-and-frailty
#14
REVIEW
Maria Lorenzi, Stefano Bonassi, Teresa Lorenzi, Silvia Giovannini, Roberto Bernabei, Graziano Onder
Sarcopenia and frailty are associated with several important health-related adverse events, including disability, loss of independence, institutionalization and mortality. Sarcopenia can be considered a biological substrate of frailty, and the prevalence of both these conditions progressively increases with age. Telomeres are nucleoprotein structures located at the end of linear chromosomes and implicated in cellular ageing, shorten with age, and are associated with various age-related diseases. In addition, telomere length (TL) is widely considered a molecular/cellular hallmark of the ageing process...
March 16, 2018: Biogerontology
https://www.readbyqxmd.com/read/29547035/bilateral-first-ray-amputation-of-the-foot-due-to-severe-tophaceous-gout-complicated-by-infection-and-discharged-sinus-a-case-report
#15
Kerim Sariyilmaz, Ilker Eren, Okan Ozkunt, Mustafa Sungur, Onder I Kilicoglu, Fatih Dikici
BACKGROUND: Gout is a purine metabolism disease. Tophaceous gout may cause joint destruction and other systemic problems and sometimes may be complicated by infection. Infection and sinus with discharge associated with tophaceous gout are serious complications, and treatment is difficult. We present a patient with tophaceous gout complicated by infection and discharging sinus treated by bilateral amputation at the level of the first metatarsus. METHODS: A 43-year-old man previously diagnosed as having gout, and noncompliant with treatment, presented with tophaceous gout associated with discharging sinus and infection on his left first metatarsophalangeal joint...
January 2018: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/29531596/dynamic-mri-evaluation-of-the-gastric-fundus-and-splenic-circulation-to-assess-the-gastric-breves-dissection-during-laparoscopic-nissen-fundoplication
#16
Gökhan Akkurt, Önder Sürgit, Hakan Ataş, Mustafa Alimoğullari
AIM: We aimed to evaluate the possible effects of dissecting gastric breves (GB) during the Laparoscopic Nissen Fundoplication (LNF) on the gastric fundus and splenic circulation using dynamic Magnetic Resonance Imaging (MRI). METHODS: In total 14 patients with gastroesophageal reflux disease (GERD) that was diagnosed with esophagogastroduodenoscopy and 24 - hour PH monitorization and undergoing LNF surgery were included. All patients underwent LNF surgery between October 2006 and March 2010...
February 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29526651/accounting-for-frailty-when-treating-chronic-diseases
#17
REVIEW
Graziano Onder, Davide L Vetrano, Alessandra Marengoni, J Simon Bell, Kristina Johnell, Katie Palmer
Chronic diseases are considered to be major determinants of frailty and it could be hypothesized that their treatment may counteract the development of frailty. However, the hypothesis that intensive treatment of chronic diseases might reduce the progression of frailty is poorly supported by existing studies. In contrast, some evidence suggests that intensive treatment of chronic diseases may increase negative health outcomes in frail older adults. In particular, if treatment of symptoms related to chronic diseases (i...
March 8, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29526414/experiences-with-a-modified-preauricular-mini-incision-with-subdermally-dissection-in-condylar-and-subcondylar-fractures-of-the-mandible
#18
Said Algan, Murat Kara, Mehmet Akif Cakmak, Onder Tan, Hakan Cinal, Ensar Zafer Barin, Akin Inaloz
OBJECTIVE: Condylar and subcondylar fractures (CSFs) are among the most common mandible fractures. If reduction of these fractures is not carried out correctly, serious complications can result, including infection, damage to temporomandibular joint (TMJ) function, malocclusion, nonunion, malunion, and ankylosis of the TMJ. METHODS: We used a preauricular, mini-incision, open technique (PMIOT) for CSF of the mandible. 66 patients (48 males, 18 females), with a total of 72 CSFs of the mandible, were repaired with PMIOT between 2011 and 2016...
February 8, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29523037/is-hba1c-level-of-diabetic-patients-associated-with-penile-prosthesis-implantation-infections
#19
Onder Canguven, Raidh Talib, Walid El Ansari, Kareim Khalafalla, Abdulla Al Ansari
BACKGROUND AND OBJECTIVES: Diabetes mellitus is an important risk factor for erectile dysfunction (ED). Penile prosthesis implantation surgery is the final solution for diabetic patients with ED, but infections thereof are still a serious risk factor. While some studies suggest that most infections associated with penile prosthesis implantation are associated to high glycated hemoglobin (HbA1c) levels, other research did support such relationship. MATERIALS AND METHODS: The current study assessed retrospectively, the association between HbA1c level and penile prosthesis surgery infection...
March 9, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29522924/anaerobic-digestion-of-chicken-manure-by-a-leach-bed-process-coupled-with-side-stream-membrane-ammonia-separation
#20
Alper Bayrakdar, Recep Önder Sürmeli, Baris Çalli
This study pioneered the use of a single-stage methanogenic leach bed reactor (LBR) for high-solids (total solid content: 14%-16%) anaerobic mono-digestion of chicken manure. Chicken manure was loaded into the LBR in cloth sachets without adding any bulking agents. Ammonia was separated and recovered by placing a hydrophobic gas diffusion membrane in a leachate collection chamber. Methane production in the membrane-integrated LBR was 0.272 m3 /kgVS and 2.3 times higher than that in the control LBR. The results revealed that using membrane-integrated LBR for anaerobic digestion is a simple and cost-efficient technology for the mono-digestion of chicken manure and ammonia removal...
February 27, 2018: Bioresource Technology
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