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https://www.readbyqxmd.com/read/28936684/kinematics-of-mobile-bearing-unicompartmental-knee-arthroplasty-compared-to-native-results-from-an-in-vitro-study
#1
Geert Peersman, Josh Slane, Philippe Vuylsteke, Susanne Fuchs-Winkelmann, Philipp Dworschak, Thomas Heyse, Lennart Scheys
INTRODUCTION: Fixed-bearing unicompartmental knee arthroplasty (UKA) closely replicates native knee kinematics. As few studies have assessed kinematics following mobile-bearing (MB) UKA, the current study aimed to investigate whether MB UKA preserves natural knee kinematics. MATERIALS AND METHODS: Seven fresh-frozen full-leg cadaver specimens were prepared and mounted in a kinematic rig that allowed all degrees of freedom at the knee. Three motion patterns, passive flexion-extension (0°-110° flexion), open-chain extension (5°-70° flexion) and squatting (30°-100° flexion), were performed pre- and post-implantation of a medial MB UKA and compared in terms of rotational and translational knee joint kinematics in the different anatomical planes, respectively...
September 21, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28933136/coexistence-of-spondyloarthritis-and-joint-hypermobility-syndrome-rare-or-unknown-association
#2
J B Pinto Carneiro, T Pinto de Souza, T M L Antunes de Oliveira, S L Euzébio Ribeiro
We report two cases of siblings presenting coexisting non-radiographic axial spondyloartrhritis and joint hypermobility syndrome, complaining of back pain with morning stiffness, enthesitis, peripheral arthralgia, high erythrocyte sedimentation rate and C-reactive protein level and positive HLA-B27. The association of these two conditions is rare, but especially interesting in view of their contrasting features, one causing axial skeleton stiffness, the other a wider range of peripheral joint movements. Coexistence of these two opposite disorders causes confusion in diagnosis and management, resulting in lower quality of life for patients, as they are in pain from the early stages...
September 21, 2017: Reumatismo
https://www.readbyqxmd.com/read/28933133/the-effect-of-nerve-mobilization-exercise-in-patients-with-rheumatoid-arthritis-a-pilot-study
#3
C-N Lo, G Xia, B P Leung
Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation of the joints. The neurogenic inflammatory mechanism plays an important role in the inflammatory process of RA, and pathological changes in neural tissues in RA have also been noted. We aim to investigate treatment of the nervous system to relieve joint pain and inflammation in RA. Nerve mobilization, a nervous system-specific therapeutic exercise, was applied on RA patients to determine the effect of nerve mobilization on joint inflammation...
September 21, 2017: Reumatismo
https://www.readbyqxmd.com/read/28932004/effects-of-pulsed-therapeutic-ultrasound-on-the-treatment-of-people-with-knee-osteoarthritis
#4
Eliana-Isabel Rodríguez-Grande, Jose-Luis Osma-Rueda, Yannely Serrano-Villar, Carolina Ramírez
[Purpose] The aim was to evaluate the effect of therapeutic ultrasound on the pain, joint mobility, muscle strength, physical function, and quality of life of people with knee OA. [Subjects and Methods] One-site, one-arm, before-after study that included people with Grade II or III tibiofemoral osteoarthritis. Ten therapeutic ultrasound sessions (duty cycle=20%, ERA=10 cm(2), BNR=6:1, SATP=2.2 W/cm(2), SATA=0.44 W/cm(2), frequency=1 MHz, time=4 minutes) were applied. Assessments of primary outcome variables: pain intensity and function, and secondary variables: joint mobility, muscle strength and quality of life, were performed at onset and end of therapy; an additional intermediate evaluation was included for the primary variables...
September 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28931991/the-treatment-effect-of-hamstring-stretching-and-nerve-mobilization-for-patients-with-radicular-lower-back-pain
#5
Ju-Hyun Lee, Tae-Ho Kim
[Purpose] In this paper, hamstring stretching and nerve mobilization are conducted on patients with radicular lower back pain, and changes to pain levels, pressure thresholds, angles of knee joint extension, and disorder levels of lower back pain were studied. [Subjects and Methods] The subjects were divided into two groups: one group conducted hamstring stretches and was comprised of 6 male and 5 female subjects, and the other group received nerve mobilization treatment and was comprised of 5 male and 6 female subjects...
September 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28929828/increased-risk-of-aseptic-loosening-for-43-525-rotating-platform-vs-fixed-bearing-total-knee-replacements
#6
Oystein Gothesen, Stein Hakon L Lygre, Michelle Lorimer, Stephen Graves, Ove Furnes
Background and purpose - Given similar functional outcomes with mobile and fixed bearings, a difference in survivorship may favor either. This study investigated the risk of aseptic loosening for the most used subtypes of mobile-bearing rotating-platform knees, in Norway and Australia. Patients and methods - Primary TKRs reported to the Norwegian and Australian joint registries, between 2003 and 2014, were analyzed with aseptic loosening as primary end-point and all revisions as secondary end-point. We hypothesized that no difference would be found in the rate of revision between rotating-platform and the most used fixed-bearing TKRs, or between keeled and non-keeled tibia...
September 20, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28919215/thermo-responsive-in-situ-forming-hydrogels-as-barriers-to-prevent-post-operative-peritendinous-adhesion
#7
Pang-Yun Chou, Shih-Heng Chen, Chih-Hao Chen, Shih-Hsien Chen, Yi Teng Fong, Jyh-Ping Chen
In this study, we aimed to assess whether thermo-responsive in-situ forming hydrogels based on poly(N-isopropylacrylamide) (PNIPAM) could prevent post-operative peritendinous adhesion. The clinical advantages of the thermo-responsive hydrogels are acting as barrier material to block penetration of fibroblasts, providing mobility and flexibility during application and enabling injection through a small opening to fill spaces of any shape after surgery. The thermo-responsiveness of hydrogels was determined to ensure their clinic uses...
September 12, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28919112/disuse-atrophy-accompanied-by-intramuscular-ectopic-adipogenesis-in-vastus-medialis-muscle-of-advanced-osteoarthritis-patients
#8
Madoka Ikemoto-Uezumi, Yasumoto Matsui, Masaki Hasegawa, Remi Fujita, Yasuhide Kanayama, Akiyoshi Uezumi, Tsuyoshi Watanabe, Atsushi Harada, A Robin Poole, Naohiro Hashimoto
Muscle dysfunction is the most important modifiable mediating factor in primary osteoarthritis because properly contracting muscles are a key absorber of forces acting on a joint. However, the pathological features of disuse muscle atrophy in osteoarthritis patients have been little studied. Vastus medialis muscles of fourteen female patients with osteoarthritis in the age range 69 to 86 years, largely immobile for one or more years, were obtained during arthroplastic surgery and analyzed histologically. These were compared to female patients without arthritis, two with patellar fracture, and two with patellar subluxation...
September 14, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28918784/-treatment-of-patellar-instability
#9
Martin Lind, Peter Faunø, Ole Gade Sørensen, Bjarne Mygind-Klavsen
First-time patellar luxation appears typically in teenagers and young adults below the age of 16 years, with a prevalence of 45/100,000/year. This luxation is treated with brief limited mobility in a bandage, and with a complementary physiotherapy if the mobility is influenced afterwards. Risk factors for patellar instability are patellofemoral dysplasia, hyperlaxity, patella alta and valgus malalignment in the knee joint. In case of repeated luxation the treatment is surgical, i.e. reconstruction of the medial patellofemoral ligament recreating the medial patella-stabilizing structures...
September 18, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28918579/analysis-of-undesirable-sequelae-of-sentinel-node-surgery-in-breast-cancer-patients-a-prospective-cohort-study
#10
Dominika Kozak, Iwona Głowacka-Mrotek, Tomasz Nowikiewicz, Zygmunt Siedlecki, Wojciech Hagner, Magdalena Sowa, Wojciech Zegarski
Use of sentinel lymph node biopsy limits the frequency and severity of sequelae of surgical treatment. However, the procedure itself may not be completely free of complications. The goal of this work was to analyze prospectively the occurrence of undesirable sequelae in patients undergoing sentinel lymph node biopsy as an isolated intervention in the axillary fossa. This prospective observational study was conducted on a group of 104 women. Patients were examined on five occasions: one day before the procedure, one day after the procedure, one month, three months, and six months after the procedure...
September 16, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28918423/non-discriminant-relationships-between-leg-muscle-strength-mass-and-gait-performance-in-healthy-young-and-old-adults
#11
Thomas Muehlbauer, Urs Granacher, Ron Borde, Tibor Hortobágyi
BACKGROUND: Gait speed declines with increasing age, but it is unclear if gait speed preferentially correlates with leg muscle strength or mass. OBJECTIVE: We determined the relationship between gait speed and (1) leg muscle strength measured at 3 lower extremity joints and (2) leg lean tissue mass (LTM) in healthy young (age: 25 years, n = 20) and old (age: 70 years, n = 20) adults. METHODS: Subjects were tested for maximal isokinetic hip, knee, and ankle extension torque, leg LTM by bioimpedance, and gait performance (i...
September 16, 2017: Gerontology
https://www.readbyqxmd.com/read/28917431/results-of-toccata-%C3%A2-resurfacing-pip-joint-arthroplasty-a-series-of-32%C3%A2-cases-at-a-mean-follow-up-of-5-9%C3%A2-years
#12
W Kim, B Renaud, P Dumontier, J-L Condamine
The objective of this study was to evaluate the long-term results of proximal interphalangeal (PIP) resurfacing arthroplasty for treating osteoarthritis: the PIP Toccata implant(®). This was a retrospective study of 32 out of 33 PIP arthroplasty cases performed with a dorsolateral or a Chamay approach by two surgeons after a minimum follow-up of 24 months. Patients were reviewed using a standardized assessment of pain, function, mobility and radiological changes. The average follow-up was 5.9 years. The mean active range of motion was 67° (15-95)...
September 13, 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28916968/hmgb-proteins-and-arthritis
#13
REVIEW
Noboru Taniguchi, Yasuhiko Kawakami, Ikuro Maruyama, Martin Lotz
The high-mobility group box (HMGB) family includes four members: HMGB1, 2, 3 and 4. HMGB proteins have two functions. In the nucleus, HMGB proteins bind to DNA in a DNA structure-dependent but nucleotide sequence-independent manner to function in chromatin remodeling. Extracellularly, HMGB proteins function as alarmins, which are endogenous molecules released upon tissue damage to activate the immune system. HMGB1 acts as a late mediator of inflammation and contributes to prolonged and sustained systemic inflammation in subjects with rheumatoid arthritis...
September 15, 2017: Human Cell
https://www.readbyqxmd.com/read/28912672/maximizing-the-potential-of-longitudinal-cohorts-for-research-in-neurodegenerative-diseases-a-community-perspective
#14
Catherine J Moody, Derick Mitchell, Grace Kiser, Dag Aarsland, Daniela Berg, Carol Brayne, Alberto Costa, Mohammad A Ikram, Gail Mountain, Jonathan D Rohrer, Charlotte E Teunissen, Leonard H van den Berg, Joanna M Wardlaw
Despite a wealth of activity across the globe in the area of longitudinal population cohorts, surprisingly little information is available on the natural biomedical history of a number of age-related neurodegenerative diseases (ND), and the scope for intervention studies based on these cohorts is only just beginning to be explored. The Joint Programming Initiative on Neurodegenerative Disease Research (JPND) recently developed a novel funding mechanism to rapidly mobilize scientists to address these issues from a broad, international community perspective...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28912633/a-preliminary-case-series-evaluating-the-safety-and-immediate-to-short-term-clinical-benefits-of-joint-mobilization-in-hemophilic-arthritis-of-the-lower-limb
#15
Emma Scaddan, John Rowell, Shaun O'Leary
OBJECTIVES: Arthritis resulting from recurrent intra-articular bleeding in individuals with hemophilia can be severely debilitating due to joint pain and stiffness with subsequent loss of mobility and function. Very limited studies have investigated the potential benefits of joint mobilization for this condition. This case series is a preliminary investigation of safety, as well as immediate and short-term clinical benefits, associated with gentle knee and ankle joint mobilization in people with hemophilic arthropathy...
September 2017: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/28912632/the-intra-rater-reliability-of-a-revised-3-point-grading-system-for-accessory-joint-mobilizations
#16
Jennifer Ward, Clair Hebron, Nicola J Petty
OBJECTIVES: Joint mobilizations are often quantified using a 4-point grading system based on the physiotherapist's detection of resistance. It is suggested that the initial resistance to joint mobilizations is imperceptible to physiotherapists, but that at some point through range becomes perceptible, a point termed R1. Grades of mobilization traditionally hinge around this concept and are performed either before or after R1. Physiotherapists, however, show poor reliability in applying grades of mobilization...
September 2017: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/28894740/increased-whole-cerebellar-serotonin-in-aged-c57bl-6-mice
#17
Nicholas W DeKorver, Dustin Lichty, Marieke van der Hart, Arash Rassoulpour, Stephen J Bonasera
Mobility and locomotor impairments have high prevalence, morbidity, and significant mortality in older adult populations. Cerebellar functional changes have been implicated in the pathogenesis of these age-related mobility and gait deficits unrelated to stroke, Parkinson's disease, or degenerative joint disease. We thus examined total cerebellar glutamate, glutamine, GABA, glycine, dopamine, norepinephrine, tryptophan, serotonin, alanine, threonine, and asparagine content from male 2-3-month (young, n = 6) and 21-24-month-old (aged, n = 6) C57BL/6 mice...
2017: Matters (Zur)
https://www.readbyqxmd.com/read/28890123/isolated-scaphotrapeziotrapezoid-osteoarthritis-treatment-using-resurfacing-arthroplasty-with-scaphoid-anchorage
#18
G Humada Álvarez, C Simón Pérez, B García Medrano, O Faour Martín, J J Marcos Rodríguez, A Vega Castrillo, M A Martín Ferrero
OBJECTIVE: The aim of this study is to show the results of scaphotrapeziotrapezoid (STT) joint osteoarthritis treatment performing resurfacing arthroplasty with scaphoid anchorage. MATERIAL AND METHOD: An observational, descriptive and retrospective study was performed. Ten patients with isolated STT joint osteoarthritis were studied between 2013 and 2015. The mean follow-up time was 26months. Clinical results, functional and subjective scores were reviewed. RESULTS: The patients were satisfied, achieving an average of 2...
September 7, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/28889222/the-predictive-factors-of-secondary-patellar-resurfacing-in-computer-assisted-total-knee-arthroplasty-a-prospective-cohort-study
#19
Florent Franck, Hervé Ouanezar, Alexandre Jacquel, Vincent Pibarot, Julien Wegrzyn
PURPOSE: The decision to resurface the patella during total knee arthroplasty (TKA) remains controversial. This prospective cohort study aimed to evaluate the outcome and survivorship of the native patella in computer-assisted TKA (CAS TKA) implanted for primary knee osteoarthritis, and to determine the predictive factors of secondary patellar resurfacing (SPR). METHODS: A prospective cohort of 273 cementless ultra-congruent mobile-bearing CAS TKA implanted without patellar resurfacing was included in our total joint registry...
September 9, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28888525/clinical-and-radiological-outcomes-following-radioscapholunate-fusion
#20
David Montoya-Faivre, Germain Pomares, Valentin Calafat, François Dap, Gilles Dautel
INTRODUCTION: Radioscapholunate (RSL) fusion is typically performed following wrist trauma. It addresses the pain caused by radiocarpal osteoarthritis but reduces the wrist's mobility. The objective of this study was to determine the long-term clinical and radiological outcomes of this procedure. MATERIALS AND METHODS: This was a retrospective study of all wrists operated for RSL fusion in our surgery unit over a 12-year period. The clinical analysis consisted of joint amplitudes, grip strength, pain (VAS) and functional scores (PRWE, QuickDash, Mayo Wrist Score)...
September 6, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
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