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https://www.readbyqxmd.com/read/28550118/s100a9-potentiates-the-activation-of-neutrophils-by-the-etiological-agent-of-gout-monosodium-urate-crystals
#1
Louis-Simon Rousseau, Guillaume Paré, Asmaa Lachhab, Paul H Naccache, François Marceau, Philippe Tessier, Martin Pelletier, Maria Fernandes
Gout is one of the most painful types of arthritis that arises when the body mounts an acute inflammatory reaction against a crystallized form of uric acid known as monosodium urate crystals (MSUs). Although MSUs are known to activate neutrophils, the most abundant leukocyte in the synovial fluid of patients with gout, few studies have investigated the effect on neutrophils of the simultaneous stimulation with MSU and proinflammatory mediators in the inflamed joint. Herein, we focused on a protein that is highly expressed in the synovium in gout, S100A9...
May 26, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28543369/directing-clinical-care-using-lower-extremity-biomechanics-in-patients-with-ankle-osteoarthritis-and-ankle-arthroplasty
#2
REVIEW
Robin Queen
Ankle osteoarthritis is a debilitating disease with approximately 50,000 new cases per year leading to skeletal deformity, severe and recurrent pain, cartilage breakdown, and gait dysfunction limiting patient mobility and well-being. Although many treatments (total ankle arthroplasty (TAA), ankle fusion (arthrodesis), and ankle distraction arthroplasty) relieve pain, it is not clear that these procedures significantly improve patient mobility. The goal of the research presented here is to summarize what is presently known about lower extremity gait mechanics and outcomes and to quantify the impact of ankle osteoarthritis and TAA have on these measures using an explicitly holistic and mechanistic approach...
May 19, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28542788/saturated-salt-solution-a-further-step-to-a-formaldehyde-free-embalming-method-for-veterinary-gross-anatomy
#3
M Lombardero, M M Yllera, A Costa-E-Silva, M J Oliveira, P G Ferreira
In the field of veterinary anatomy, most of the specimens used in practical sessions are perfused with fixatives. Thus, they can be used for a longer time, reducing the number of animals for educational purposes. Formalin is the most commonly used fixative, consisting of a 37% formaldehyde solution. However, formaldehyde is a powerful irritant of the eyes and airways and is considered carcinogenic, causing nasopharyngeal cancer in exposed workers and professionals. In the present study, we explored an alternative method to avoid the use of formaldehyde in specimens used for gross anatomy practical sessions...
May 24, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28542704/trabecular-and-cortical-bone-structure-of-the-talus-and-distal-tibia-in-pan-and-homo
#4
Zewdi J Tsegai, Matthew M Skinner, Andrew H Gee, Dieter H Pahr, Graham M Treece, Jean-Jacques Hublin, Tracy L Kivell
OBJECTIVES: Internal bone structure, both cortical and trabecular bone, remodels in response to loading and may provide important information regarding behavior. The foot is well suited to analysis of internal bone structure because it experiences the initial substrate reaction forces, due to its proximity to the substrate. Moreover, as humans and apes differ in loading of the foot, this region is relevant to questions concerning arboreal locomotion and bipedality in the hominoid fossil record...
May 24, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28538534/enhanced-recovery-after-surgery-for-hip-and-knee-replacements
#5
David P Gwynne-Jones, Ginny Martin, Chris Crane
BACKGROUND: Enhanced recovery after surgery (ERAS) programs or hip and knee replacements have had a significant effect on streamlining patient care with shorter stays, no increase in complications, and improved outcomes including reduced mortality. PURPOSE: To compare outcomes following the introduction of an ERAS program for hip and knee replacements developed at our institution with a historical cohort of patients. METHODS: ERAS protocols were developed at our institution for patients undergoing hip and knee joint replacements...
May 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/28536820/crescent-fractures-of-the-pelvis-treated-by-open-reduction-and-internal-fixation-a-critique-of-day-s-guidelines
#6
K Venugopal Menon, S S Suresh, Sivaprasad Kalyanasundaram, Jacob Varughese
INTRODUCTION: Day's classification and treatment guidelines are considered the gold standard in crescent fractures of the pelvis. The objective of this study was to retrospectively evaluate 10 surgically treated crescent fractures of the pelvis in the context of Day's recommendations. METHODS: This is a retrospective cohort study. Ten consecutive cases of crescent fractures that were treated surgically at a level 1 trauma center formed the cohort. Six were operated anteriorly, three posteriorly and one percutaneously...
May 23, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28534175/-aseptic-loosening-of-total-ankle-replacement-two-stage-revision-with-bone-augmentation-of-osseous-defects-and-secondary-prosthesis-implantation
#7
A Barg, M Wiewiorski, V Valderrabano
OBJECTIVE: To remove loosened ankle prosthesis components, perform osseous defect augmentation, and reimplant definitive prosthesis components to preserve ankle range of motion. INDICATIONS: Aseptic loosening of the tibial and/or talar ankle prosthesis components with substantial bone defect. CONTRAINDICATIONS: General surgical/anesthesiological risks, infections, critical soft tissue conditions, nonmanageable hindfoot instability, neurovascular impairment of the lower extremity, neuroarthropathy, substantial nonreconstructable osseous defects with or without cysts on the tibial and/or talar side, noncompliance, primary total ankle replacement (TAR) using intramedullary fixation (stem fixation), severely reduced bone quality, insulin-dependent diabetes mellitus, smoking, unrealistic patients' expectations, high activity in sports...
May 22, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28533851/-giant-cell-tumors-of-the-tendon-sheaths-of-the-hand-about-50-cases
#8
Walid Osman, Zeineb Alaya, Ali Haggui, Mohamed Ben Rejeb, Sonia Jemni, Nader Naouar, Mohamed Laziz Ben Ayeche
Giant cell tumors of the synovial tendon sheaths (GCTSTS) are a localized form of hemopigmented villonodular synovitis. They mainly affect the hands. This study aims to analyse the epidemiology, clinical and therapeutic characteristics of GCTSTS, to assess the results of surgical treatment and to identify risk factors for recurrences. We conducted a retrospective data collection from medical records of 50 patients with GCTSTS of the hand between 1992 and 2016 in the Department of Orthopaedics at the Hospital of Sahloul (Sousse-Tunisia)...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28532889/effect-of-self-myofascial-release-on-myofascial-pain-muscle-flexibility-and-strength-a-narrative-review
#9
Leonid Kalichman, Chen Ben David
BACKGROUND: Numerous techniques have been employed to treat myofascial pain syndrome. Self-myofascial release (SMFR) is a relatively new technique of soft tissue mobilization. The simplicity and portability of the SMFR tools allow it to be easily implemented in any type of fitness or rehabilitation program. It is an active method and can be used by anyone at home or at the workplace. OBJECTIVE: To review the current methods of SMFR, their mechanisms, and efficacy in treating myofascial pain, improving muscle flexibility and strength...
April 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28523897/congenital-indurated-skin-lesions-with-impaired-joint-mobility
#10
Engin Sezer, Julia S Lehman, Emel Dasgin
No abstract text is available yet for this article.
May 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28523427/-total-ankle-arthroplasty-with-simultaneous-subtalar-fusion
#11
J Mainzer, P Rippstein
OBJECTIVE: Pain free weight bearing ability with orthograde hindfoot position and preserved tibiotalar motion. INDICATIONS: Symptomatic arthritis of the ankle and subtalar joint, additional subtalar hindfoot malalignment. CONTRAINDICATIONS: Absolute: acute infection, noncorrectable ligamentous instability or bony defects, restricted perfusion, diabetic foot syndrome. Relative: inability to comply with postoperative partial weight bearing, only moderate symptoms of subtalar arthritis, smoking, intricate soft tissue situation...
May 18, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28523314/health-related-quality-of-life-in-patients-with-hallux-valgus
#12
Lavinia Maria Hogea, Bogdan Gheorghe Hogea, Laura Alexandra Nussbaum, Mirela Loredana Grigoraş, Bogdan Corneliu Andor, Codrina Mihaela Levai, Ana Cristina Bredicean
BACKGROUND AND AIMS: No deformity of the forefoot occurs more frequently than hallux valgus (HV), which is considered to be medial deviation of the first metatarsal and lateral deviation and rotation of the hallux, either with or without medial soft tissue enlargement of the metatarsal head. The HV deformity can lead to painful motion of the joint or difficulty in daily joint activity that often requires surgical correction. The aims of this study were to investigate the levels of foot pain and quality of life of patients with HV before and after surgery...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28521689/relationship-between-rheumatoid-arthritis-disease-activity-assessed-with-the-us7-score-and-quality-of-life-measured-with-questionnaires-haq-eq-5d-wpai
#13
Martina Skácelová, Skácelová Martina, Horák Pavel, Heřmanová Zuzana, Langová Kateřina
BACKGROUND: Rheumatoid arthritis is a chronic disease considerably affecting the quality of life of patients, their functional abilities and capability to work. In everyday clinical practice, the condition is commonly monitored by assessing the disease activity using a joint count and laboratory markers of inflammation with calculating the DAS28 or other systems for scoring the disease activity. OBJECTIVES: This study is aimed to evaluate the benefit of ultrasound examination with a standardized instrument and correlate its results with the quality of life of patients and their functional abilities as assessed by standardized questionnaire methods...
May 17, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28514231/preoperative-pain-neuroscience-education-combined-with-knee-joint-mobilization-for-knee-osteoarthritis-a-randomized-controlled-trial
#14
Enrique Lluch, Lirios Dueñas, Deborah Falla, Isabel Baert, Mira Meeus, Jose Sánchez-Frutos, Jo Nijs
OBJECTIVES: This study aimed to first compare the effects of a preoperative treatment combining pain neuroscience education (PNE) with knee joint mobilization versus biomedical education with knee joint mobilization on central sensitization (CS) in patients with knee osteoarthritis, both before and after surgery. Second, we wanted to compare the effects of both interventions on knee pain, disability, and psychosocial variables. MATERIALS AND METHODS: Forty-four patients with knee osteoarthritis were allocated to receive 4 sessions of either PNE combined with knee joint mobilization or biomedical education with knee joint mobilization before surgery...
May 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28512080/using-text-messaging-in-long-term-arthroplasty-follow-up-a-pilot-study
#15
Oliver Blocker, Alison Bullock, Rhidian Morgan-Jones, Adel Ghandour, James Richardson
BACKGROUND: Patient-reported outcome measures (PROMs) and mobile technology have the potential to change the way patients are monitored following joint replacement surgery. OBJECTIVE: The aim of this study was to determine the feasibility of text messaging to record PROMs in long-term follow-up of hip and knee arthroplasty. Our participants were 17 patients 2-years-plus post hip or knee arthroplasty attending clinic with a mobile telephone number on record. METHODS: A simple PROM (Oswestry Very Short Form) was texted to the patient...
May 16, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28507875/digital-joint-reconstruction-with-osteotendinous-joint-allograft-experimental-study-in-rats
#16
Martin Iglesias, Ángel Uriel Cruz-Reyes, Patricia Butrón, Ricardo Hernández-Agallo, Víctor Antonio Torres de la Barrera, Claudio Reyes-Montero, Marta Durand-Carbajal, Gonzalo Torres-Villalobos
BACKGROUND: Fresh or frozen nonvascularized osteotendinous joint allografts (OTJA) have not been used previously, clinically or experimentally, for metacarpophalangeal joint reconstruction. Therefore, we evaluated the viability of OTJA for metatarsophalangeal joint (MTJ) reconstruction in rats. METHODS: In the experimental group of 12 Lewis rats, we reconstructed the MTJ of the third digit of the hindlimb with a fresh, nonvascularized OTJA obtained from the same digit from 12 donor rats...
April 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28507779/spinal-osteotomies-indications-limits-and-pitfalls
#17
REVIEW
Kamil Cagri Kose, Omer Bozduman, Ali Erkan Yenigul, Servet Igrek
The aims of spinal deformity surgery are to achieve balance, relieve pain and prevent recurrence or worsening of the deformity.The main types of osteotomies are the Smith-Petersen osteotomy (SPO), pedicle subtraction osteotomy (PSO), bone-disc-bone osteotomy (BDBO) and vertebral column resection (VCR), in order of increasing complexity.SPO is a posterior column osteotomy in which the posterior ligaments and the facet joints are removed and correction is performed through the disc space. A mobile anterior disc is essential...
March 2017: EFORT Open Rev
https://www.readbyqxmd.com/read/28507186/zygapophyseal-joint-fusion-in-ankylosing-spondylitis-assessed-by-computed-tomography-associations-with-syndesmophytes-and-spinal-motion
#18
Sovira Tan, Jianhua Yao, John A Flynn, Lawrence Yao, Michael M Ward
OBJECTIVE: Because zygapophyseal joints (ZJ) are difficult to visualize on radiographs, little is known about the relationship of ZJ fusion to other features of spinal damage in ankylosing spondylitis (AS). We used computed tomography (CT) to investigate the concordance of ZJ fusion and syndesmophytes, and examined the contribution of both features to spinal motion. METHODS: We performed thoracolumbar CT scans (T10-T11 to L3-L4) on 55 patients. Two readers scored scans for ZJ fusion, which were compared to syndesmophyte height and extent of bridging, measured by computer algorithm at the same levels...
May 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28503144/rigid-ankle-foot-orthosis-deteriorates-mediolateral-balance-control-and-vertical-braking-during-gait-initiation
#19
Arnaud Delafontaine, Olivier Gagey, Silvia Colnaghi, Manh-Cuong Do, Jean-Louis Honeine
Rigid ankle-foot orthoses (AFO) are commonly used for impeding foot drop during the swing phase of gait. They also reduce pain and improve gait kinematics in patients with weakness or loss of integrity of ankle-foot complex structures due to various pathological conditions. However, this comes at the price of constraining ankle joint mobility, which might affect propulsive force generation and balance control. The present study examined the effects of wearing an AFO on biomechanical variables and electromyographic activity of tibialis anterior (TA) and soleus muscles during gait initiation (GI)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28502109/reproductive-performance-of-resident-and-migrant-males-females-and-pairs-in-a-partially-migratory-bird
#20
Hannah Grist, Francis Daunt, Sarah Wanless, Sarah J Burthe, Mark A Newell, Mike P Harris, Jane M Reid
1.Quantifying among-individual variation in life-history strategies, and associated variation in reproductive performance and resulting demographic structure, is key to understanding and predicting population dynamics and life-history evolution. Partial migration, where populations comprise a mixture of resident and seasonally-migrant individuals, constitutes a dimension of life-history variation that could be associated with substantial variation in reproductive performance. However, such variation has rarely been quantified due to the challenge of measuring reproduction and migration across a sufficient number of seasonally-mobile males and females...
May 14, 2017: Journal of Animal Ecology
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