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https://www.readbyqxmd.com/read/29166721/-a-preliminary-study-on-the-relationship-between-idiopathic-arrhythmia-and-cardiac-magnetic-resonance-imaging-defined-cardiac-features-in-patients-with-straight-back-syndrome
#1
L Chen, X H Ma, L Zhao, R Bai, S N Li, L Wang, H Chen, Z M Fan, M W Lou, Y D Niu
Objective: To retrospectively analyze the potential correlation between cardiac magnetic resonance (CMR) imaging and clinical features and idiopathic arrhythmia in patients with straight back syndrome (SBS). Methods: Patients receiving CMR imaging examination from April 2015 to March 2016 at our department (n=1 432) were screened, 76 patients met the diagnosis criteria of flat chest (anteroposterior diameter/transthoracic diameter (APD/TTD) ratio<0.37 at the T8 vertebra). After excluding 33 patients with structural heart disease, 43 SBS patients were divided into two groups: SBS without obvious morphological change in the heart (group A, n=19) and SBS with morphological change of the heart (group B, n=24)...
November 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29166675/perianal-dermatitis-its-incidence-and-patterns-of-topical-therapies-in-a-level-iv-neonatal-intensive-care-unit
#2
Anuj Malik, Emily Witsberger, Lesley Cottrell, Autumn Kiefer, Panitan Yossuck
Objective To define the incidence of perianal dermatitis (PD) and determine the usage pattern and cost efficacy of diaper products among neonates admitted to a level IV neonatal intensive care unit (NICU) including those with a diagnosis of neonatal abstinence syndrome (NAS). Methods A retrospective cohort study to evaluate neonates with PD based on number of orders for Aquaphor, Bagbalm, Desitin, Flanders, or Nystatin. Various demographic and clinical parameters were recorded. Usage patterns of these five products were analyzed, and their costs estimated...
November 22, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/29166672/increased-risk-of-dementia-following-herpes-zoster-ophthalmicus
#3
Ming-Chieh Tsai, Wan-Ling Cheng, Jau-Jiuan Sheu, Chung-Chien Huang, Ben-Chang Shia, Li-Ting Kao, Herng-Ching Lin
This retrospective cohort study aimed to examine the relationship between herpes zoster ophthalmicus (HZO) and the subsequent risk of dementia using a population-based database. We retrieved the study sample from the Taiwan Longitudinal Health Insurance Database 2005. The study group included 846 patients with HZO, and the comparison group included 2538 patients without HZO. Each patient was individually followed for a 5-year period to identify those patients who subsequently received a diagnosis of dementia...
2017: PloS One
https://www.readbyqxmd.com/read/29166483/processed-and-ultra-processed-food-consumption-among-children-aged-13-to-35-months-and-associated-factors
#4
Mônica Araujo Batalha, Ana Karina Teixeira da Cunha França, Sueli Ismael Oliveira da Conceição, Alcione Miranda Dos Santos, Francelena de Sousa Silva, Luana Lopes Padilha, Antônio Augusto Moura da Silva
The aim of this study was to evaluate the consumption of processed and ultra-processed foods among children aged 13-35 months and its associated factors. We studied 1,185 children within the BRISA cohort in São Luís, Maranhão State, Brazil. The food consumption was investigated using a 24-hour recall, and the percentages of daily caloric intake and nutrients were estimated by food groups according to "NOVA" classification. We chose to categorize children belonging to the upper tertile of the distribution as having a high consumption of processed and ultra-processed food products...
November 21, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29166446/maternal-education-and-age-inequalities-in-neonatal-death
#5
Sandra Costa Fonseca, Patricia Viana Guimarães Flores, Kenneth Rochel Camargo, Rejane Sobrino Pinheiro, Claudia Medina Coeli
OBJECTIVE: Evaluate the interaction between maternal age and education level in neonatal mortality, as well as investigate the temporal evolution of neonatal mortality in each stratum formed by the combination of these two risk factors. METHODS: A nonconcurrent cohort study, resulting from a probabilistic relationship between the Mortality Information System and the Live Birth Information System. To investigate the risk of neonatal death we performed a logistic regression, with an odds ratio estimate for the combined variable of maternal education and age, as well as the evaluation of additive and multiplicative interaction...
November 17, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29166443/epifloripa-aging-cohort-study-methods-operational-aspects-and-follow-up-strategies
#6
Ione Jayce Ceola Schneider, Susana Cararo Confortin, Carla de Oliveira Bernardo, Carolina Carvalho Bolsoni, Danielle Ledur Antes, Karine Gonçalves Pereira, Lariane Mortean Ono, Larissa Pruner Marques, Lucélia Justino Borges, Maruí Weber Corseuil Giehl, Rodrigo de Rosso Krug, Vanessa Fernanda Goes, Alexandra Crispim Boing, Antônio Fernando Boing, Eleonora d'Orsi
OBJECTIVE: To describe the sample plan, operational aspects, and strategies used in the 2009/2010 and 2013/2014 EpiFloripa Aging Study. METHODS: The EpiFloripa Aging is a population-based longitudinal study with 1,705 older adults (60 years or more) living in the municipality of Florianópolis, State of Santa Catarina, Brazil, in 2009/2010 (baseline). The research was conducted with a face-to-face interviews, organized into blocks of identification, socioeconomic, mental health, health and life habits, global functionality, falls, physical activity, morbidities, use of health services, use of medications, food, oral health, and violence, evaluated in the first (2009/2010) and in the second wave (2013/2014)...
2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29166413/comprehensive-molecular-profiling-of-718-multiple-myelomas-reveals-significant-differences-in-mutation-frequencies-between-african-and-european-descent-cases
#7
Zarko Manojlovic, Austin Christofferson, Winnie S Liang, Jessica Aldrich, Megan Washington, Shukmei Wong, Daniel Rohrer, Scott Jewell, Rick A Kittles, Mary Derome, Daniel Auclair, David Wesley Craig, Jonathan Keats, John D Carpten
Multiple Myeloma (MM) is a plasma cell malignancy with significantly greater incidence and mortality rates among African Americans (AA) compared to Caucasians (CA). The overall goal of this study is to elucidate differences in molecular alterations in MM as a function of self-reported race and genetic ancestry. Our study utilized somatic whole exome, RNA-sequencing, and correlated clinical data from 718 MM patients from the Multiple Myeloma Research Foundation CoMMpass study Interim Analysis 9. Somatic mutational analyses based upon self-reported race corrected for ancestry revealed significant differences in mutation frequency between groups...
November 2017: PLoS Genetics
https://www.readbyqxmd.com/read/29166407/executive-function-assessment-in-new-zealand-2-year-olds-born-at-risk-of-neonatal-hypoglycemia
#8
Judith M Ansell, Trecia A Wouldes, Jane E Harding
A growing number of babies are born with perinatal risk factors that may impair later development. These children are often assessed at 2 years to help predict outcome and direct support services. Executive function is an important predictor of academic achievement and behavior, but there are limited assessments of executive function in 2-year-olds and few have been tested in at-risk populations. Therefore, we developed a battery of four age-appropriate tasks to assess executive function in 2-year-olds. At 24 months' corrected age 368 children completed tasks assessing attention, inhibition, working memory and cognitive flexibility...
2017: PloS One
https://www.readbyqxmd.com/read/29166380/food-and-nutrient-intakes-in-young-adults-born-preterm
#9
Hanna-Maria Matinolli, Satu Männistö, Marika Sipola-Leppänen, Marjaana Tikanmäki, Kati Heinonen, Johan G Eriksson, Dieter Wolke, Aulikki Lano, Marjo-Riitta Järvelin, Marja Vääräsmäki, Katri Räikkönen, Eero Kajantie
BACKGROUND: Adults born preterm have higher levels of cardiometabolic risk factors than their term-born peers. Studies have suggested that at least those born smallest eat less healthily. We examined the association between early (<34 weeks) and late (34 to 36 weeks) preterm birth and diet and food preferences in adult age. METHODS: Participants of two cohort studies located in Finland completed a validated food frequency questionnaire(FFQ) at age 24y to assess their usual diet and the adherence to healthy eating guidelines by using a recommended diet index(RDI)...
November 22, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29166361/the-impact-of-hepatectomy-time-of-the-liver-graft-on-post-transplant-outcome-a-eurotransplant-cohort-study
#10
Ina Jochmans, Steffen Fieuws, Ineke Tieken, Undine Samuel, Jacques Pirenne
OBJECTIVE: Assessing the effect of donor hepatectomy time on outcome after transplantation. SUMMARY OF BACKGROUND DATA: When blood supply in a deceased organ donor stops, ischemic injury starts. Livers are cooled to reduce cellular metabolism and minimize ischemic injury. This cooling is slow and livers are lukewarm during hepatectomy, potentially affecting outcome. METHODS: We used the Eurotransplant Registry to investigate the relationship between donor hepatectomy time and post-transplant outcome in 12,974 recipients of deceased-donor livers (January 1, 2004, to December 31, 2013)...
November 21, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29166344/two-stage-prosthetic-breast-reconstruction-a-comparison-between-prepectoral-and-partial-subpectoral-techniques
#11
Maurice Y Nahabedian, Costanza Cocilovo
BACKGROUND: Prosthetic breast reconstruction with prepectoral placement may confer clinical advantages compared with subpectoral placement. The purpose of this study was to assess and compare clinical outcomes following 2-stage reconstruction following prepectoral and partial subpectoral placement of tissue expanders and implants. METHODS: A retrospective review of 39 (prepectoral) and 50 (partial subpectoral) patients was completed. Acellular dermal matrix was used in all patients...
December 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29166308/an-evaluation-of-the-choice-for-contralateral-prophylactic-mastectomy-and-patient-concerns-about-recurrence-in-a-reconstructed-cohort
#12
Ian C Sando, Jessica I Billig, Shoshana W Ambani, Casey T Kraft, Kelley M Kidwell, Lin Zhong, Kevin C Chung, Adeyiza O Momoh
BACKGROUND: Rising contralateral prophylactic mastectomy rates are a subject of national concern. This study assessed (1) factors critical to patients when deciding on contralateral prophylactic mastectomy and (2) patients' quality of life related to concerns about recurrence after unilateral or bilateral breast reconstruction. METHODS: Patients with stage 0 to III breast cancer who underwent unilateral mastectomy or contralateral prophylactic mastectomy and breast reconstruction at a single institution between 2000 and 2012 were identified...
November 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29166302/hierarchical-semi-bayes-methods-for-misclassification-in-perinatal-epidemiology
#13
Richard F MacLehose, Lisa M Bodnar, Craig Meyer, Haitao Chu, Timothy L Lash
BACKGROUND: Validation data are used to estimate the extent of misclassification in epidemiologic studies. In the Penn MOMS cohort, prepregnancy BMI is subject to misclassification and validation data are available to estimate the extent of misclassification. We use these data to estimate the association between maternal prepregnancy body mass index and early preterm (<32 weeks) birth using a semi-Bayes hierarchical model allowing for more flexible adjustment for misclassification...
November 18, 2017: Epidemiology
https://www.readbyqxmd.com/read/29166301/can-we-train-machine-learning-methods-to-outperform-the-high-dimensional-propensity-score-algorithm
#14
Mohammad Ehsanul Karim, Menglan Pang, Robert W Platt
The use of retrospective healthcare claims datasets is frequently criticized for the lack of complete information on potential confounders. Utilizing patient's health status-related information from claims datasets as surrogates or proxies for mismeasured and unobserved confounders, the high-dimensional propensity score algorithm enables us to reduce bias. Using a previously published cohort study of post-myocardial infarction statin use (1998 - 2012), we compare the performance of the algorithm with a number of popular machine learning approaches for confounder selection in high-dimensional covariate spaces: random forest, least absolute shrinkage and selection operator, and elastic net...
November 18, 2017: Epidemiology
https://www.readbyqxmd.com/read/29166293/applicability-of-the-calcaneal-apophysis-ossification-staging-system-to-the-modern-pediatric-population
#15
Samuel Q Li, Allen D Nicholson, Daniel R Cooperman, Raymond W Liu
BACKGROUND: The calcaneal apophysis ossification staging system is a novel method for assessing skeletal maturity. However, it was created using the same historic patient population that was used to create the Greulich and Pyle atlas of the hand and wrist, predominantly white children. It is unclear if the calcaneal apophysis ossification staging system is still applicable to the modern pediatric population and to children of other races. METHODS: We retrospectively studied 1327 benign lateral foot x-rays from modern white and black children...
November 21, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29166170/highly-accurate-identification-of-cystic-precursor-lesions-of-pancreatic-cancer-through-targeted-mass-spectrometry-a-phase-iic-diagnostic-study
#16
Karolina S Jabbar, Liisa Arike, Caroline S Verbeke, Riadh Sadik, Gunnar C Hansson
Purpose Pancreatic cystic lesions are common incidental findings on imaging, but up to half may be forerunners of pancreatic cancer. Therefore, accurate differential diagnosis is crucial for correct patient management. Unfortunately, currently available diagnostic methods cannot robustly identify premalignant and malignant pancreatic cystic lesions. Methods Cyst fluid samples obtained by routine endoscopic ultrasound-guided aspiration were used for the analyses. In a cohort of 24 patients, eight biomarker candidates for malignant potential and high-grade dysplasia/cancer were identified by an explorative proteomic approach...
November 22, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29165912/reproducibility-of-radioactive-iodine-uptake-raiu-measurements
#17
Matthieu Pelletier-Galarneau, Patrick Martineau, Ran Klein, Matthew Henderson, Lionel S Zuckier
BACKGROUND: Measurement of radioactive iodine uptake (RAIU) is an important aspect of the assessment and treatment of patients with hyperthyroidism. Its uncertainty affects how much of a true change in RAIU can be detected as well as appropriateness of the therapy dosage upon which it is based. In this study, a method of estimating the reproducibility and least significant change (LSC) values for RAIU measurements, and the implications of the values observed are discussed, with emphasis on application to quality assurance initiatives...
November 22, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29165860/rehabilitation-and-convalescent-hospital-stay-in-new-south-wales-an-analysis-of-3-979-women-aged-75
#18
Catherine Chojenta, Julie Byles, Balakrishnan Kichu Nair
OBJECTIVES: With a rapidly ageing population, it is imperative to examine health service costs and plan appropriately for the future. This paper determines the factors related to extended hospital stay for 'Rehabilitation' or 'Convalescence', as defined by ICD-10 coding, in acute hospital settings for older women in New South Wales, Australia. METHODS: Participants were from the 1921-26 cohort of the Australian Longitudinal Study on Women's Health. For this analysis, self-reported survey data were linked to the NSW Admitted Patient Data Collection and the National Death Index...
November 22, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/29165853/past-year-prescription-drug-monitoring-program-opioid-prescriptions-and-self-reported-opioid-use-in-an-emergency-department-population-with-opioid-use-disorder
#19
Kathryn Hawk, Gail D'Onofrio, David A Fiellin, Marek C Chawarski, Patrick G O'Connor, Patricia H Owens, Michael V Pantalon, Steven L Bernstein
BACKGROUND: Despite increasing reliance on Prescription Drug Monitoring Programs (PDMPs) as a response to the opioid epidemic, the relationship between aberrant drug-related behaviors captured by the PDMP and opioid use disorder is incompletely understood. How PDMP data should guide Emergency Department (ED) assessment has not been studied. STUDY OBJECTIVE: To evaluate a relationship between PDMP opioid prescription records and self-reported non-medical opioid use of prescription opioids in a cohort of opioid dependent ED patients enrolled in a treatment trial...
November 22, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29165849/a-novel-public-health-threat-high-lead-solder-in-stainless-steel-rainwater-tanks-in-tasmania
#20
Kerryn Lodo, Cameron Dalgleish, Mahomed Patel, Mark Veitch
OBJECTIVE: We identified two water tanks in Tasmania with water lead concentrations exceeding the Australian Drinking Water Guidelines (ADWG) limit; they had been constructed with stainless steel and high-lead solder from a single manufacturer. An investigation was initiated to identify all tanks constructed by this manufacturer and prevent further exposure to contaminated water. METHODS: To identify water tanks we used sales accounts, blood and water lead results from laboratories, and media...
November 22, 2017: Australian and New Zealand Journal of Public Health
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