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https://www.readbyqxmd.com/read/28944997/desire-for-parenthood-and-reproductive-health-knowledge-in-adolescents-and-young-adults-with-sickle-cell-disease-and-their-caregivers
#1
Leena Nahata, Nicole M Caltabellotta, Kyle Ball, Sarah H O'Brien, Susan E Creary
BACKGROUND/OBJECTIVE: Sickle cell disease (SCD) and hydroxyurea have implications for fertility and reproductive health. The goal of this study was to examine desire for parenthood and reproductive health knowledge among a cohort of adolescent and young adult (AYA) with SCD receiving hydroxyurea and their caregivers at a large pediatric academic center. METHODS: Patients with SCD were approached from September 2016 to July 2017 if they were: (1) 12-20 years old, (2) prescribed hydroxyurea for at least 6 months, (3) proficient in English, and (4) accompanied by a caregiver who was proficient in English and willing to participate...
September 25, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28944967/risk-for-chromosomal-aberrations-in-apparently-isolated-intra-uterine-growth-restriction-a-systematic-review
#2
REVIEW
Lena Sagi-Dain, Amir Peleg, Shlomi Sagi
OBJECTIVE: To perform a systematic review examining the risk of chromosomal aberrations in apparently isolated intra-uterine growth restriction (IUGR). METHODS: Search was conducted by research librarian in five databases. By independent screening of 2894 references, two investigators selected original studies examining the risk of chromosomal aberrations in apparently isolated IUGR diagnosed at the second and third trimesters using ultrasound. We excluded studies describing IUGR combined with additional fetal anomalies detected by ultrasound and those where fetuses with structural anomalies or aneuploidy were not reported...
September 25, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28944954/multicentre-cohort-study-to-define-and-validate-pathological-assessment-of-response-to-neoadjuvant-therapy-in-oesophagogastric-adenocarcinoma
#3
F Noble, M A Lloyd, R Turkington, E Griffiths, M O'Donovan, J R O'Neill, S Mercer, S L Parsons, R C Fitzgerald, T J Underwood
BACKGROUND: This multicentre cohort study sought to define a robust pathological indicator of clinically meaningful response to neoadjuvant chemotherapy in oesophageal adenocarcinoma. METHODS: A questionnaire was distributed to 11 UK upper gastrointestinal cancer centres to determine the use of assessment of response to neoadjuvant chemotherapy. Records of consecutive patients undergoing oesophagogastric resection at seven centres between January 2000 and December 2013 were reviewed...
September 25, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28944936/smoking-cessation-in-workplace-settings-quit-rates-and-determinants-in-a-group-behaviour-therapy-programme
#4
Yann Hausherr, Carlos Quinto, Leticia Grize, Christian Schindler, Nicole Probst-Hensch
INTRODUCTION: To capitalise on the opportunities that the smoking ban legislation in Switzerland offers for the prevention of tobacco-related diseases, a smoking cessation programme in a workplace setting was developed and implemented in companies across the language and cultural regions of Switzerland. Our goal was to identify factors associated with relapse into smoking that may be overcome during training sessions or that should be considered for the optimisation of future interventions...
September 25, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28944933/emergency-department-management-of-body-packers-and-body-stuffers
#5
Liv Heymann-Maier, Lionel Trueb, Sabine Schmidt, Pierre-Nicolas Carron, Olivier Hugli, Eric Heymann, Bertrand Yersin
Trafficking and sale of narcotics frequently involves the intra-abdominal transport of large quantities of drugs, usually cocaine or heroin ("body packing"), or, when there is a risk of being arrested, the oral ingestion of minor quantities of narcotics dedicated for immediate resale ("body stuffing"). This study aimed to describe the characteristics, complications and medical follow through of 132 cases of body packing (n = 36), cases of body stuffing (n = 83) or mixed cases (n = 13), referred by the authorities to our emergency department over the course of 12 years...
September 25, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28944929/oncogenic-mir%C3%A2-132-sustains-proliferation-and-self%C3%A2-renewal-potential-by-inhibition-of-polypyrimidine-tract%C3%A2-binding-protein-2-in-glioblastoma-cells
#6
Silong Lou, Jia Ji, Xin Cheng, Jian Ruan, Rong Li, Zhengjun Guo
Glioblastoma multiforme (GBM) is the leading type of brain tumor, exhibiting unlimited proliferation and invasion potential. The present study indicated that a high expression level of miR‑132 was detected in the neural subtype of GBM and predicted an unfavorable prognosis for patients from The Cancer Genome Atlas cohort (n=526). Cox hazard regression analysis demonstrated miR‑132 as an independent prognostic indicator for GBM patients. Further in vitro experiments indicated that miR‑132 promoted the proliferation and sphere formation of U87 cells...
September 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944755/the-intriguing-effect-of-delay-time-to-sentinel-lymph-node-biopsy-on-survival-a-propensity-score-matching-study-on-a-cohort-of-melanoma-patients
#7
Antonio Tejera-Vaquerizo, Miguel Angel Descalzo-Gallego, Victor Traves, Celia Requena, Isidro Bolumar, Angel Pla, Eduardo Nagore
BACKGROUND: Time between primary melanoma excision and sentinel lymph node biopsy (SLNB) has not been sufficiently studied as an independent predictor of survival in cutaneous melanoma. OBJECTIVES: We used propensity score matching to evaluate whether early SLNB (performed ≤40 days from excisional biopsy) is associated with higher mortality in patients with cutaneous melanoma. MATERIALS & METHODS: A retrospective cohort study at a tertiary melanoma referral centre...
September 23, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28944650/acute-and-overuse-injuries-in-elite-archers
#8
Claudia K Niestroj, Volker Schöffl, Thomas Küpper
BACKGROUND: To evaluate type and incidence of acute and overuse injuries in high level European and German competitive archers. METHODS: Participants of the German National Indoor Championship (DM) 2012 in Solingen, Germany, and European Outdoor Championship (EM) 2012 in Amsterdam, The Netherlands, participated in the study. The design was a retrospective cohort study performed by a questionnaire. Data obtained included standard personal data (age, gender), training habits, draw weight, competition experience, and detailed data about acute and overuse injuries that occurred during the entire sporting career of the archers...
September 22, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28944632/-student-pursuing-a-bachelor-of-science-in-nursing-160-between-process-of-professionalization-and-professional-development-in-swiss-and-belgien
#9
Myriam Graber, Veronique Haberey-Knuessi
The predictable shortage of nursing staff, in Switzerland as in the rest of Europe, continues to highlight a recurring problem for public health policy. The issue here is not just questions about the care and treatment of patients or the quality of such care, but also about the conditions necessary for adequate staff recruitment and the long-term professional engagement of health care personnel. Training in nursing care at the Universities of Applied Science of Western Switzerland is also indirectly concerned by rationalisation measures currently in force in the public Activé par Editorial Manager® et Preprint Manager® appartenant à Aries Systems Corporation health sector...
April 19, 2017: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/28944615/agreement-between-weight-status-and-perceived-body-size-and-the-association-with-body-size-satisfaction-in-children
#10
Iris Leppers, Henning Tiemeier, Sonja A Swanson, Frank C Verhulst, Vincent W V Jaddoe, Oscar H Franco, Pauline W Jansen
OBJECTIVE: Extensive evidence suggests that children and adolescents often inaccurately perceive their body size. However, the extent of this misperception is unclear. This paper describes the agreement between children's actual weight and the perception of body size (self-reported and maternally reported) and the association of actual weight with self-reported body satisfaction. METHODS: In a population-based cohort study of 3,408 children aged 9 to 10 years, we assessed the children's self-perception and ideal perception of their body size with the Children's Body Image Scale...
September 25, 2017: Obesity
https://www.readbyqxmd.com/read/28944598/dentition-status-and-frailty-in-community-dwelling-older-adults-a-5-year-prospective-cohort-study
#11
Masanori Iwasaki, Akihiro Yoshihara, Misuzu Sato, Kumiko Minagawa, Mieko Shimada, Mamoru Nishimuta, Toshihiro Ansai, Yutaka Yoshitake, Hideo Miyazaki
AIM: To examine the longitudinal association between dentition status and incidence of frailty in older adults. METHODS: The present prospective cohort study included community-dwelling Japanese adults aged 75 years at baseline (n = 322). Dental examinations, biochemical blood examinations, physical performance and anthropometric measurements, and structured questionnaires were carried out at baseline. The presence of ≥20 teeth with nine or more occluding pairs of teeth was defined as functional dentition...
September 24, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28944596/diet-quality-in-patients-with-end-stage-kidney-disease-undergoing-dialysis
#12
Lauren A Roach, Kelly Lambert, Jane L Holt, Barbara J Meyer
BACKGROUND: People on haemodialysis (HD) are at risk of consuming a poor quality diet. This includes inadequate intake of omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA). OBJECTIVE: This study aims to investigate diet quality, with a particular focus on n-3 LCPUFA intake, in a population of incentre HD patients. DESIGN: Dietary intake was measured using three 24 hour recalls; the Polyunsaturated food frequency questionnaire (PUFA FFQ) and the Total Diet Score (TDS)...
September 24, 2017: Journal of Renal Care
https://www.readbyqxmd.com/read/28944447/serotonin-reuptake-inhibitors-and-mortality-in-epilepsy-a-linked-primary-care-cohort-study
#13
Colin B Josephson, Arturo Gonzalez-Izquierdo, Spiros Denaxas, Natalie K Fitzpatrick, Tolulope T Sajobi, Jordan D T Engbers, Scott Patten, Nathalie Jette, Samuel Wiebe
OBJECTIVE: Preliminary evidence suggests that serotonin reuptake inhibitor (SRI) use may increase postictal respiratory drive and prevent death. We sought to determine whether SRIs are associated with improved all-cause and possible seizure-specific mortality in patients with epilepsy. METHODS: Patients with epilepsy and a random 10:1 sample without epilepsy were extracted from The ClinicAl research using LInked Bespoke studies and Electronic health Records (CALIBER) resource...
September 24, 2017: Epilepsia
https://www.readbyqxmd.com/read/28944432/trend-of-changes-in-serum-albumin-and-its-relation-with-sex-age-and-bmi-following-laparoscopic-mini-gastric-bypass-surgery-in-morbid-obese-cases
#14
Mehrdad Karimi, Ali Kabir, Masoumeh Nejatifar, Abdolreza Pazouki
BACKGROUND: The aim of this study is to investigate the pattern of changes in serum albumin level after mini-gastric bypass (MGB) and its association with gender, age, and body mass index (BMI) of the patients. METHODS: This cohort study was conducted on 196 morbidly obese patients undergoing MGB followed for 1 year. The data on BMI, serum albumin level, demographic, anthropometric, biochemical variables and comorbidities were gathered before and after (3, 6, and 12 months) surgery...
September 24, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28944414/the-spectrum-of-skin-biopsies-and-excisions-in-a-pediatric-skin-center
#15
Martin Theiler, Kathrin Neuhaus, Katrin Kerl, Lisa Weibel
Little is known about the spectrum of pediatric skin disorders requiring biopsy/excision, their indication, impact on further management, and the accuracy of clinical diagnosis. We aimed to address these questions in the patient population seen at our Swiss University referral center for Pediatric Dermatology and Plastic Surgery. All skin biopsies/excisions performed in patients aged ≤ 16 years over a period of 2 years were retrospectively analyzed. A total of 506 samples were included. The majority of biopsies/excisions (n = 413, 82%) was performed for tumors, cysts, and hamartomas and 18% for other skin conditions...
September 25, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28944403/prediction-of-disease-free-survival-by-the-pet-ct-radiomic-signature-in-non-small-cell-lung-cancer-patients-undergoing-surgery
#16
Margarita Kirienko, Luca Cozzi, Lidija Antunovic, Lisa Lozza, Antonella Fogliata, Emanuele Voulaz, Alexia Rossi, Arturo Chiti, Martina Sollini
PURPOSE: Radiomic features derived from the texture analysis of different imaging modalities e show promise in lesion characterisation, response prediction, and prognostication in lung cancer patients. The present study aimed to identify an images-based radiomic signature capable of predicting disease-free survival (DFS) in non-small cell lung cancer (NSCLC) patients undergoing surgery. METHODS: A cohort of 295 patients was selected. Clinical parameters (age, sex, histological type, tumour grade, and stage) were recorded for all patients...
September 24, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28944368/impact-of-prosthetic-material-on-mid-and-long-term-outcome-of-dental-implants-supporting-single-crowns-and-fixed-partial-dentures-a-systematic-review-and-meta-analysis
#17
Samir Abou-Ayash, Malin Strasding, Gerta Rücker, Wael Att
AIM: The impact of prosthetic material selection on implant survival is not clear. The current criteria for choosing a prosthetic material seem to be based on clinician preferences. This systematic review aims to evaluate the impact of restorative materials on the mid- and long-term survival of implants supporting single crowns and fixed partial dentures. MATERIALS AND METHODS: Hand and MEDLINE searches were performed to identify relevant literature for single crowns (SC) and fixed partial dentures (FPD)...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28944360/immediate-loading-of-fixed-prostheses-in-fully-edentulous-jaws-1-year-follow-up-from-a-single-cohort-retrospective-study
#18
Francesco Giordano, Marco Esposito
PURPOSE: To evaluate the clinical outcome of four to five implants immediately restored with metal-resin screw-retained cross-arch fixed prostheses in edentulous jaws 1 year after loading. MATERIALS AND METHODS: In total, 104 consecutive patients received four 11 × 4.5 mm implants with a torque superior to 35 Ncm. If one implant did not reach a torque superior to 35 Ncm a fifth implant was added. If two implants did not reach a torque superior to 35 Ncm, loading was postponed after 3 months...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28944359/crestal-sinus-lift-using-an-implant-with-an-internal-l-shaped-channel-1-year-after-loading-results-from-a-prospective-cohort-study
#19
Marco Tallarico, David L Cochran, Erta Xhanari, Claudia Dellavia, Elena Canciani, Eitan Mijiritsky, Silvio Mario Meloni
PURPOSE: To evaluate the clinical and radiographic outcomes of a one-stage crestal sinus elevation procedure using a self-tapping endosseous implant system (iRaise, Maxillent, Herzliya, Israel) developed for sinus augmentation, 1 year after loading. MATERIALS AND METHODS: Patients needing restoration in the posterior maxilla with a residual alveolar crest of 3 to 8 mm in height and 5 mm in width distal to the canine as measured on CBCT scan were treated using the iRaise sinus lift system...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28944301/intravenous-rehydration-of-malnourished-children-with-acute-gastroenteritis-and-severe-dehydration-a-systematic-review
#20
Kirsty A Houston, Jack G Gibb, Kathryn Maitland
Background: Rehydration strategies in children with severe acute malnutrition (SAM) and severe dehydration are extremely cautious. The World Health Organization (WHO) SAM guidelines advise strongly against intravenous fluids unless the child is shocked or severely dehydrated and unable to tolerate oral fluids. Otherwise, guidelines recommend oral or nasogastric rehydration using low sodium oral rehydration solutions. There is limited evidence to support these recommendations. Methods: We conducted a systematic review of randomised controlled trials (RCTs) and observational studies on 15 (th) June 2017 comparing different strategies of rehydration therapy in children with acute gastroenteritis and severe dehydration, specifically relating to intravenous rehydration, using standard search terms...
2017: Wellcome Open Research
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