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https://www.readbyqxmd.com/read/29439360/aerobic-rehabilitation-program-for-improving-muscle-function-in-parkinson-s-disease
#1
Siria Di Martino, Caterina Tramonti, Elisa Unti, Claudia Del Gamba, Ubaldo Bonuccelli, Bruno Rossi, Roberto Ceravolo, Carmelo Chisari
BACKGROUND: Parkinson's Disease (PD) is characterized by progressive and disabling symptoms. An impaired oxidative metabolism efficiency was supposed to be involved in the systemic impairment. Rehabilitative treatment represents a valid tool in promoting skeletal muscle's adaptations, even if no solid studies on muscle metabolic features are still available. OBJECTIVE: To evaluate the efficiency of skeletal muscle oxidative metabolism in PD patients in comparison with age-matched controls and test the role of an intensive aerobic treatment on muscle oxidative metabolism and its clinical effects...
2018: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29438396/children-s-peer-violence-perpetration-and-victimization-prevalence-and-associated-factors-among-school-children-in-afghanistan
#2
Julienne Corboz, Osman Hemat, Wahid Siddiq, Rachel Jewkes
BACKGROUND: Child peer violence is a global problem and seriously impacts children's physical and psychological health, and their education outcomes. There are few research studies on children's peer violence available in South Asian countries, particularly in Afghanistan. This paper describes the prevalence of children's peer violence perpetration and victimization and associated factors among school children in Afghanistan. METHODS: A total of 770 children were recruited into a baseline study conducted as part of an intervention evaluation in 11 schools (seven girls' and four boys' schools)...
2018: PloS One
https://www.readbyqxmd.com/read/29428074/machine-learning-techniques-for-breast-cancer-computer-aided-diagnosis-using-different-image-modalities-a-systematic-review
#3
REVIEW
Nisreen I R Yassin, Shaimaa Omran, Enas M F El Houby, Hemat Allam
BACKGROUND AND OBJECTIVE: The high incidence of breast cancer in women has increased significantly in the recent years. Physician experience of diagnosing and detecting breast cancer can be assisted by using some computerized features extraction and classification algorithms. This paper presents the conduction and results of a systematic review (SR) that aims to investigate the state of the art regarding the computer aided diagnosis/detection (CAD) systems for breast cancer. METHODS: The SR was conducted using a comprehensive selection of scientific databases as reference sources, allowing access to diverse publications in the field...
March 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29414704/protein-dynamics-of-the-sensor-protein-hemat-as-probed-by-time-resolved-step-scan-ftir-spectroscopy
#4
Andrea Pavlou, Hideaki Yoshimura, Shigetoshi Aono, Eftychia Pinakoulaki
The heme-based aerotactic transducer (HemAT) is an oxygen-sensor protein consisting of a sensor and a signaling domain in the N- and C-terminal regions, respectively. Time-resolved step-scan FTIR spectroscopy was employed to characterize protein intermediate states obtained by photolysis of the carbon monoxide complexes of sensor-domain, full-length HemAT, and the Y70F (B-helix), L92A (E-helix), T95A (E-helix), and Y133F (G-helix) HemAT mutants. We assign the spectral components to discrete substructures, which originate from a helical structure that is solvated (1638 cm-1) and a native helix that is protected from solvation by interhelix tertiary interactions (1654 cm-1)...
February 6, 2018: Biophysical Journal
https://www.readbyqxmd.com/read/29390336/hemophagocytic-lymphohistiocytosis-complicated-by-multiorgan-failure-a-case-report
#5
Federica Lovisari, Valeria Terzi, Monica G Lippi, Paolo R Brioschi, Roberto Fumagalli
RATIONALE: We present a case of hemophagocytic lymphohistiocytosis (HLH) with severe pulmonary complication and acute respiratory distress syndrome (ARDS) hospitalized in our intensive care unit (ICU) in 2014; distinctive trait of this case has been the challenging diagnosis, with a bone marrow biopsy always negative, the severe pulmonary complication with ARDS and severe pulmonary hypertension, and the ferritin temporal kinetics that precisely followed the clinical course of disease...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29356716/chronic-hematic-cyst-of-the-right-maxillary-sinus-and-orbit-presenting-as-proptosis
#6
Martin Ochoa-Escudero, Diego A Herrera, Arthur B Dublin
A 28-year-old man presented to the emergency room complaining of right proptosis. He also manifested eye pain and facial fullness and redness in this side. Seven years ago, he had right hemifacial gunshot trauma treated with surgical reconstruction. The CT scan showed expansion of the right maxillary sinus due to a hypodense nonenhancing lesion extending to the nasal cavity, masticatory space, and extraconal space of the orbit. MRI was performed showing high signal intensity of the lesion on T2-weighted images indicating a cystic nature...
January 19, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29348341/draft-genome-sequence-of-escherichia-coli-strain-sn137-a-bacterium-with-extracellular-proteolytic-activity-on-immunoglobulins-and-persistence-in-human-tissue-blood
#7
Salustio Najera-Hernandez, Maria Patricia Sanchez-Alonso, Estela Anastacio-Marcelino, Erasmo Negrete-Abascal, Candelario Vazquez-Cruz
The draft genome sequence of Escherichia coli strain SN137 is reported here. The genome comprises 172 contigs, corresponding to 4.9 Mb with 50% G+C content, and contains several genes related to pathogenicity that explain its survival in human hematic tissue.
January 18, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29317884/evaluation-of-the-anti-schistosomal-effects-of-turmeric-curcuma-longa-versus-praziquantel-in-schistosoma-mansoni-infected-mice
#8
Atef Hussein, Samia Rashed, Ibrahim El Hayawan, Rabab El-Sayed, Hemat Ali
Background: Curcumin is the major active ingredient of Curcuma longa L., traditionally known as turmeric and has been shown to exhibit a wide range of pharmacological activities including anti-parasitic effect. However, it is found to be water-insoluble and has low bioavailability. The aim of this study was to explore the potential role of turmeric solved in olive oil either alone or in combination with praziquantel (PZQ) in treatment of schistosomiasis mansoni. Methods: The whole turmeric powder suspended in olive oil (as a solvent) is indicated to S...
October 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29303777/evaluation-of-serum-beta-endorphin-and-substance-p-in-knee-osteoarthritis-patients-treated-by-laser-acupuncture
#9
Nagwa Mohammed, Hemat Allam, Eman Elghoroury, Emad N Zikri, Ghada A Helmy, Aliaa Elgendy
Background Laser acupuncture is one of the complementary modalities used for treating osteoarthritis. The study was performed to evaluate the effectiveness of laser acupuncture in the treatment of grade 2 knee osteoarthritis. Patients and methods Forty patients having bilateral knee osteoarthritis were divided into two groups (20 patients in each group). The patients of the first group were subjected to 12 laser sessions at the following acupoints (St 35, St36, Sp9, Sp10 and Gb 34). During each session, laser of 90 mw was directed to each acupoint for 1 min giving energy of 5...
January 5, 2018: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/29219053/triazolopyrimidines-and-thiazolopyrimidines-synthesis-anti-hsv-1-cytotoxicity-and-mechanism-of-action
#10
Salwa F Mohamed, Eman M H Abbas, Hemat S Khalaf, Thoraya A Farghaly, Dina N Abd El-Shafy
Merged pyrimidine derivatives were designed by one pot synthesis of pyrimidinethione derivative with halogenated compounds. The structure of all prepared compounds was characterized by their spectroscopic data and also, their ability to inhibit the in vitro replication of HSV-1 was estimated. Amongst the tested compounds 2-acetyl-3-methyl-5-(p-tolyl)indeno[1,2-d]thiazolo[3,2-a]pyrimidin-6(5H)-one (9b) and ethyl 3-methyl-6-oxo-5-(p-tolyl)-5,6-dihydroindeno[1,2-d]thiazolo[3,2-a]pyrimidine-2-carboxylate (9c), caused viral inhibition over 90%...
December 7, 2017: Mini Reviews in Medicinal Chemistry
https://www.readbyqxmd.com/read/29159505/biochemical-stress-evaluation-after-medial-parapatellar-and-subvastus-approach-in-total-knee-replacement
#11
L Sabatini, G Nicolaci, F Atzori, A Oliva, A Aprato, M Terzolo, A Masse'
INTRODUCTION: Even if different surgical approaches for total knee arthroplasty are well known since decades, the standard medial parapatellar incision remains the most common one; general agreement about significant advantages with minimally invasive techniques is lacking. Furthermore, the surgical stress effect on the organism has always been analyzed through blood inflammatory parameters. This study aim was to compare the standard and subvastus approaches, using the salivary cortisol in particular as measure for systemic surgery-related stress...
November 20, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/29082726/-differential-diagnosis-and-management-of-abnormal-uterine-bleeding-in-adolescence
#12
Tiziano Motta, Antonio S Laganà, Gaetano Valenti, Valentina L LA Rosa, Marco Noventa, Amerigo Vitagliano, Benito Chiofalo, Agnese M Rapisarda, Diego Rossetti, Salvatore G Vitale
Abnormal uterine bleeding (AUB) is defined as any atypical genital bleeding originating from the uterine cavity, without the characteristics of normal menstrual period. AUB is an important symptom both for adolescents and their parents, and it usually leads to a state of anxiety. Although about 95% of AUB could be considered as a dysfunctional disorder, AUB requires well-defined diagnostic procedures in order to detect a physical cause, ruling out complex or systemic diseases, including oncological ones. Diagnostic procedures require the acquisition of a full and detailed history, and it is also crucial to obtain as much compliance from the patient as possible...
December 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28915945/potentiometric-sensor-for-non-invasive-lactate-determination-in-human-sweat
#13
Massimo Onor, Stefano Gufoni, Tommaso Lomonaco, Silvia Ghimenti, Pietro Salvo, Fiodor Sorrentino, Emilia Bramanti
The present work describes a non invasive lactate sensing in sweat during workout. The sensing system is based on a non-equilibrium potentiometric measure performed using disposable, chemically modified, screen printed carbon electrodes (SPCEs) that can be wetted with sweat during the exercise. The potentiometric signal, which is proportional to lactate concentration in sweat, is produced by a redox reaction activated by UV radiation, as opposed to the enzymatic reaction employed in traditional, blood-based measuring devices...
October 9, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28876054/probing-the-role-of-the-heme-distal-and-proximal-environment-in-ligand-dynamics-in-the-signal-transducer-protein-hemat-by-time-resolved-step-scan-ftir-and-resonance-raman-spectroscopy
#14
Andrea Pavlou, Andreas Loullis, Hideaki Yoshimura, Shigetoshi Aono, Eftychia Pinakoulaki
HemAT is a heme-containing oxygen sensor protein that controls aerotaxis. Time-resolved step-scan FTIR studies were performed on the isolated sensor domain and full-length HemAT proteins as well as on the Y70F (B-helix), L92A (E-helix), T95A (E-helix), and Y133F (G-helix) mutants to elucidate the effect of the site-specific mutations on the ligand dynamics subsequent to CO photolysis. The mutations aimed to perturb H-bonding and electrostatic interactions near the heme Fe-bound gaseous ligand (CO) and the heme proximal environment...
October 10, 2017: Biochemistry
https://www.readbyqxmd.com/read/28868841/factors-that-influence-the-occurrence-of-multiple-pregnancies-after-intracytoplasmic-injection-cycles-with-two-or-three-fresh-embryo-transfers
#15
Mahbubeh Abdollahi, Reza Omani Samani, Mandana Hemat, Arezoo Arabipoor, Fatemeh Shabani, Farzad Eskandari, Masoud Salehi
Background: Multiple pregnancies are an important complication of assisted reproductive technology (ART). The present study aims to indentify the risk factors for multiple pregnancies independent of the number of transferred embryos. MATERIALS AND METHODS: This retrospective study reviewed the medical records of patients who underwent intracytoplasmic sperm injection (ICSI) cycles in Royan Institute between October 2011 and January 2012. We entered 12 factors that affected the number of gestational sacs into the poisson regression (PR) model...
October 2017: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/28856593/the-role-of-some-feed-additives-in-fish-fed-on-diets-contaminated-with-cadmium
#16
Mohamed Salah Ayyat, Hemat Kamal Mahmoud, Abd El-Aziz Mohamed El-Hais, Khaled Mahmoud Abd El-Latif
The decline of cadmium pollution in fish farms is needed by any adequate method. The present study was designed to explore the effect of dietary cadmium contamination and its amelioration by using dietary clay, probiotic (Bactocell®), vitamin C, and vitamin E supplementation in Nile tilapia fish diet on growth rate, feed efficiency, blood components, and cadmium residues. Fish were separated into 15 groups, each group of fish was stocked into three aquaria and each contains 20 fishes. The fish of the first five groups were fed the basal diet, the second five groups were fed the basal diet contaminated with 25 mg cadmium/kg, and the third five groups were fed the same diet contaminated with 50 mg cadmium/kg...
October 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28657651/diet-and-cancer-prevention-dietary-compounds-dietary-micrornas-and-dietary-exosomes
#17
Zarrin Banikazemi, Hemat Aghagolzadeh Haji, Mohsen Mohammadi, Gholamreza Taheripak, Elmira Iranifar, Mohsen Poursadeghiyan, Abdullah Moridikia, Bahman Rashidi, Mohsen Taghizadeh, Hamed Mirzaei
Cancer is one of main health public problems worldwide. Several factors are involved in beginning and development of cancer. Genetic and internal/external environmental factors can be as important agents that effect on emerging and development of several cancers. Diet and nutrition may be as one of important factors in prevention or treatment of various cancers. A large number studies indicated that suitable dietary patterns may help to cancer prevention or could inhibit development of tumor in cancer patients...
June 28, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28635993/head-and-neck-vascular-anomalies-a-multidisciplinary-approach-and-diagnostic-criteria
#18
L Moneghini, V Sangiorgio, D Tosi, G Colletti, F Melchiorre, V Baraldini, D Graziani, R M Alfano, G Vercellio, G Bulfamante
Vascular anomalies represent a heterogeneous group of pathologies of the circulatory system that can affect any type of hematic and /or lymphatic vessel of different diameter or anatomic site. The extreme variability of tissue types and districts involved by these lesions determines a wide heterogeneity of clinical manifestations, resulting in involvement of different medical expertise. In this context, a commonly agreed terminology is crucial for the appropriate evaluation and multidisciplinary management of patients...
March 2017: Pathologica
https://www.readbyqxmd.com/read/28631886/nlrp3-expression-and-urinary-hsp72-in-relation-to-biomarkers-of-inflammation-and-oxidative-stress-in-diabetic-nephropathy-patients
#19
Hemat El-Sayed El-Horany, Rania Nagi Abd-Ellatif, Mona Watany, Yasser M Hafez, Hanaa Ibrahim Okda
Diabetic nephropathy (DN) is one of the major causes of end-stage renal disease. Nod-like receptors nucleotide-binding domain and leucine-rich repeat pyrin-3 domain (NLRP3) inflammasome displays a considerable role in the chronic inflammatory state observed in diabetic patients. Urinary heat shock protein 72 (uHSP72) is a sensitive and specific biomarker for the early detection of acute kidney injury. The aim of this study was to evaluate NLRP3 relative gene expression, its correlation with inflammatory and oxidative stress markers, and to assess the value of uHSP72 in the early detection of DN in type 2 diabetic patients with different degrees of DN...
August 2017: IUBMB Life
https://www.readbyqxmd.com/read/28616270/urinothorax-a-systematic-review
#20
María E Toubes, Adriana Lama, Lucía Ferreiro, Antonio Golpe, José M Álvarez-Dobaño, Francisco J González-Barcala, Esther San José, Nuria Rodríguez-Núñez, Carlos Rábade, Tamara Lourido, Luis Valdés
BACKGROUND: The characteristics of patients with urinothorax (UT) are poorly defined. METHODS: A systematic review was performed searching for studies reporting clinical findings, pleural fluid (PF) characteristics, and the most effective treatment of UT. Case descriptions and retrospective studies were included. RESULTS: The review included 78 studies with a total of 88 patients. Median age was 45 years, male/female ratio was 1.6:1 and in 76% of cases the etiology was trauma...
May 2017: Journal of Thoracic Disease
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