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Cysticercosis

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https://www.readbyqxmd.com/read/28728879/identification-of-universal-diagnostic-peptide-candidates-for-neglected-tropical-diseases-caused-by-cestodes-through-the-integration-of-multi-genome-wide-analyses-and-immunoinformatic-predictions
#1
Sebastián Miles, Marco Navatta, Sylvia Dematteis, Gustavo Mourglia-Ettlin
Neglected tropical diseases caused by helminth infections currently affect millions of people worldwide. Among them, there are three tapeworm species of outstanding importance: Echinococcus granulosus, E. multilocularis, and Taenia solium, which are responsible for cystic echinococcosis, alveolar echinococcosis, and cysticercosis, respectively. Despite several attempts, there is still a need for an effective and low-cost serological diagnostic test that can be used in endemic countries. In the present work, we described an innovative bioinformatic workflow for a rational prediction of putative peptide candidates for one-step serological diagnosis of any of these infections...
July 17, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28711534/primary-intradural-extramedullary-cervical-spinal-cysticercosis
#2
Vetrivel Muralidharan, Bijesh Ravindran Nair, Bimal Patel, Vedantam Rajshekhar
BACKGROUND: Spinal cysticercosis has been reported only in 0.7 to 3.0% of patients with neurocysticercosis. Most of the patients with spinal cysticercosis have a coexisting intracranial disease. Most often these present as intradural extramedullary lesions, involving thoracic and lumbar regions or intramedullary lesions. Intradural extramedullary primary spinal cysticercosis presenting as cervical myelopathy is extremely rare and not reported till date. CASE DESCRIPTION: The authors describe a 56 year old man from the northeastern part of India with progressive spastic quadriparesis...
July 12, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28697986/temporalis-cysticerci-a-diagnostic-dilemma-and-review-of-literature
#3
S Malik, G Singh, G Kaur
Cysticercosis is a systemic parasitic infestation caused by ingesting the eggs of the pork tapeworm, Taenia solium. The central nervous system (CNS) is the most important primary site of infection and disease can present with solitary or multiple space-occupying lesion. Other organs like subcutaneous tissues, muscles, heart, liver, lungs, and peritoneum are more frequently affected but maxillofacial region involvement is rare. The diagnosis of cysticercose is evoked on US examination and CT scan, but confirmation is only possible by Fine needle aspiration cytology [FNAC] or histological examination in case of surgical removal of the oral lesion which can identify the Taenia solium larva...
July 8, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28673685/controversies-in-the-treatment-of-seizures-associated-with-neurocysticercosis
#4
REVIEW
Gagandeep Singh, Ravina Sharma
Seizures are the commonest manifestation of brain parenchymal cysticercosis. In terms of pathophysiological basis and prognostic significance of the seizures, a distinction might be applied between viable cysts, solitary cysticercus granuloma and calcific cysticerci. A number of uncertainties shroud the management of seizures in people with neurocysticercosis (NCC). Although antihelminthic treatment is effective in eliminating viable cysts and possibly cysticercus granulomas, its effect on seizure outcome remains uncertain...
June 30, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28669015/present-status-of-laboratory-diagnosis-of-human-taeniosis-cysticercosis-in-europe
#5
REVIEW
M A Gómez-Morales, T Gárate, J Blocher, B Devleesschauwer, G S A Smit, V Schmidt, M J Perteguer, A Ludovisi, E Pozio, P Dorny, S Gabriël, A S Winkler
Human cysticercosis (CC) is a parasitic zoonosis caused by the larval stage (cyst) of the Taenia solium. Cysts can establish in the human central nervous system (neurocysticercosis, NCC) and other organs and tissues; they also develop in pigs, the natural intermediate host. Human taeniosis may be caused by T. solium, Taenia saginata and Taenia asiatica tapeworms; these infections are usually asymptomatic, but show a significant relevance as they perpetuate the parasites' life cycle, and, in the case of T. solium, they are the origin of (N)CC...
July 1, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28666412/an-integrated-study-of-human-and-animal-infectious-disease-in-the-lake-victoria-crescent-small-holder-crop-livestock-production-system-kenya
#6
Eric M Fèvre, William A de Glanville, Lian F Thomas, Elizabeth A J Cook, Samuel Kariuki, Claire N Wamae
BACKGROUND: The neglected zoonotic diseases (NZD) are an understudied group that are a major cause of illness throughout the developing world. In general, little is known about the prevalence and burden of NZDs in affected communities, particularly in relation to other infectious diseases with which they are often co-endemic. We describe the design and descriptive epidemiological outputs from an integrated study of human and animal zoonotic and non-zoonotic disease in a rural farming community in western Kenya...
June 30, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28658414/herd-level-spatial-cluster-analysis-of-bovine-cysticercosis-in-the-state-of-para%C3%A3-ba-northeastern-brazil
#7
Amanda Rafaela Alves Maia, Paulo Sérgio de Arruda Pinto, Rafaella Paola Meneguete Dos Guimarães Peixoto, Letícia Ferreira da Silva, Leise Gomes Fernandes, Carolina de Sousa Américo Batista Santos, Clebert José Alves, Sérgio Santos de Azevedo
The aim of this survey was to identify spatial clustering of bovine cysticercosis-positive herds in the state of Paraíba. The state was divided into three sampling groups: sampling stratum 1 (Sertão mesoregion), sampling stratum 2 (Borborema mesoregion) and sampling stratum 3 (Zona da Mata and Agreste mesoregions), and 2382 cows aging ≥ 24 months from 474 farms were sampled. Serological diagnoses of bovine cysticercosis were initially done by means of indirect ELISA, and positive serum samples were confirmed by a immunoblot test...
June 22, 2017: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/28631659/subcutaneous-cysticercosis-presenting-as-cervical-swelling-amazing-and-unexpected-cytological-findings
#8
Punam Prasad Bhadani, Iffat Jamal, Shashikant Kumar, Shuchi Smita
No abstract text is available yet for this article.
April 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28615882/isolated-cysticercosis-involving-the-anterior-abdominal-wall-a-rare-case-report
#9
Pooja Jaiswal, Yogesh Kumar Yadav, Somil Jaiswal, Nilam Bhasker
Isolated cysticercosis of anterior abdominal wall without parasitosis of central nervous system is very rare and may mimic a tumor leading to diagnostic and therapeutic dilemma. Histopathological examination plays an important role in making a definitive diagnosis. Here we report a case of a 13-year old Muslim girl presenting with swelling and pain in left lower abdomen which was clinically diagnosed as lipoma. On histopathological examination cysticercus with surrounding inflammation was seen. Since cysticercosis is a preventable disease, early and accurate diagnosis is necessary for the reduction of disease burden in the endemic areas...
June 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28607832/headaches-more-common-among-epilepsy-sufferers-with-neurocysticercosis-than-other-structural-brain-lesions
#10
Erin K Saito, Bijal Mehta, Frances Wang, Beau Nakamoto, Aaron M McMurtray
Neurocysticercosis is a leading cause of seizures and epilepsy in the developing world. Cysticercosis is endemic in many regions of Central and South America, sub-Saharan Africa, India, and Asia. Neurocysticercosis is of emerging importance because globalization has increased travel between Hawai'i and disease-endemic areas. Headache and epilepsy are two of the most common complications of neurocysticercosis infection. Currently, it is not known if epilepsy patients with neurocysticercosis are more likely to have headaches than those with other structural brain lesions or those with no structural brain abnormalities...
June 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28606690/antiparasitic-treatment-of-neurocysticercosis-the-effect-of-cyst-destruction-in-seizure-evolution
#11
REVIEW
Hector H Garcia, Oscar H Del Brutto
Antiparasitic agents against Taenia solium cysticercosis have been in use since 1979, although its use has been questioned on the basis that cysts would die naturally and thus treatment-induced inflammation is unnecessary. In addition, isolated reports have also questioned whether neurocysticercosis (NCC) is a cause of epilepsy. After more than three and a half decades, a large body of evidence is available. Little if any doubt exists about NCC as a cause of seizures - NCC is consistently associated with seizures when appropriate groups are compared, and in a large subset of cases, seizure semiology correlates with the anatomical location of lesions...
June 9, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28606366/herd-level-seroprevalence-and-associated-risk-factors-for-bovine-cysticercosis-in-the-state-of-para%C3%A3-ba-northeastern-brazil
#12
Amanda R A Maia, Leise G Fernandes, Paulo S A Pinto, Rafaella P M Guimarães-Peixoto, Letícia F Silva, Carolina S A B Santos, Clebert J Alves, Inácio J Clementino, Sérgio S Azevedo
This study focused on estimating the herd-level and animal-level prevalences, and identifying risk factors associated with bovine cysticercosis in the State of Paraíba, Northeastern Brazil. The state was divided into three sampling strata: Sertao, Borborema and Zona da Mata/Agreste. For each sampling stratum, herd-level and animal-level prevalences were estimated by a two-stage sampling survey. First, a pre-established number of herds (primary sampling units) were randomly selected; second, within each herd a pre-established number of cows aged ≥24months were systematically selected (secondary sampling units)...
July 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28588685/lumbar-spinal-intradural-neurocysticercosis-a-case-report
#13
Shizhong Zhang, Yanyan Hu, Zhen Li, Li Zhao, Zhigang Wang
Neurocysticercosis is a parasitic disease that results from the larvae of Taenia solium. While neurocysticercosis is considered as the most common parasitic infection of the nervous system, spinal neurocysticercosis is rare. The present case study investigated a 59-year-old woman, who was admitted to our hospital with pain in the bilateral lower limbs and urinary complaints in the form of straining of micturition with increasing frequency. Magnetic resonance imaging revealed an intradural extramedullary lesion extending from L1/2 to S1 of the spine...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28581268/significance-of-serology-by-multi-antigen-elisa-for-tissue-helminthiases-in-korea
#14
Yan Jin, Eun Min Kim, Min Ho Choi, Myoung Don Oh, Sung Tae Hong
It is clinically important to differentiate tissue-invading helminthiasis. The purpose of this study was to assess the specific immunoglobulin G (IgG) antibody positive rates for clonorchiasis, paragonimiasis, cysticercosis, and sparganosis 4 helminthiases from 1996 to 2006 using multi-antigen enzyme-linked immunosorbent assay (ELISA) in Korea. Results of 6,017 samples, which were referred to our institute for serodiagnosis, were analyzed. The subjects with positive serum IgG antibodies were 1,502 (25.0%) for any of the 4 helminthiases...
July 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28579023/fatal-pulmonary-cysticercosis-caused-by-cysticercus-longicollis-in-a-captive-ring-tailed-lemur-lemur-catta
#15
Amer Alić, Adnan Hodžić, Vedad Škapur, Alma Šeho Alić, Senad Prašović, Georg G Duscher
Here we describe fatal pulmonary cysticercosis caused by Cysticercus longicollis, the larval stage of Taenia crassiceps in a 15-year-old female ring-tailed lemur (Lemur catta) from Sarajevo Zoo. After sudden death, the lemur was subjected to necropsy and large multicystic structure, subdivided with fibrous septa and filled with numerous translucent, oval to ellipsoid bladder-like cysts (cysticerci), almost completely replacing right lung lobe was observed. In addition, numerous free and encysted cysticerci were found in the thoracic cavity...
July 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28575043/radiological-evolution-of-porcine-neurocysticercosis-after-combined-antiparasitic-treatment-with-praziquantel-and-albendazole
#16
Carla Cangalaya, Javier A Bustos, Juan Calcina, Ana Vargas-Calla, Javier Mamani, Diego Suarez, Gianfranco Arroyo, Armando E Gonzalez, Juan Chacaltana, Cristina Guerra-Giraldez, Siddhartha Mahanty, Theodore E Nash, Héctor H García
BACKGROUND: The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms. This inflammation can occur at the first days of therapy. So, changes in the brain cysts appearance may be detected by medical imaging. We evaluated radiological changes in the appearance of brain cysts (enhancement and size) on days two and five after the onset of antiparasitic treatment using naturally infected pigs as a model for human NCC...
June 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28569208/development-of-a-health-education-intervention-strategy-using-an-implementation-research-method-to-control-taeniasis-and-cysticercosis-in-burkina-faso
#17
Helena Ngowi, Ivan Ozbolt, Athanase Millogo, Veronique Dermauw, Télesphore Somé, Paul Spicer, Lori L Jervis, Rasmané Ganaba, Sarah Gabriel, Pierre Dorny, Hélène Carabin
BACKGROUND: Taeniasis and cysticercosis are two diseases caused by Taenia solium, a parasite transmitted between humans and pigs, leading to considerable economic loss and disabilities. Transmission of the parasite is linked to environmental and behavioural factors such as inadequate sanitation and hygiene, poor pig management, and consumption of infected pork. This study used implementation research method to design a health education intervention strategy for reducing T. solium infections in Burkina Faso, a country endemic for the parasite...
June 1, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28553397/solitary-intramedullary-cervical-cysticercosis-without-neurological-deficit-a-rare-case-report
#18
Rahul Ranjan, Tulika, Suresh Chand, Akhil Agnihotri
Neurocysticercosis is commonly seen intracranially and its incidence in the spinal cord is very low. Among spine dorsal region is more common due to more blood flow in this region and it is usually associated with lesion at other sites. The intramedullary location is rarer than extramedullary. Hence, solitary intramedullary cervical spine cysticercosis (ICC) is extremely rare entity. Only a handful numbers of cases are reported in the literature. All reported cases are presented with the neurological deficit as spinal canal diameter is very low and any space occupying lesion is not tolerated...
January 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28552103/needs-of-exploring-the-burden-of-recent-onset-seizures-due-to-neurocysticercosis-and-challenges-in-southeast-asia-focusing-on-scenario-in-malaysia
#19
REVIEW
Priyadarshi S Sahu, Yvonne A L Lim, Rohela Mahmud, Sushela D Somanath, Chong T Tan, C P Ramachandran
Seizures due to neurocysticercosis (NCC) is a neglected human-to-human transmitted disorder and an emerging problem worldwide. A substantial portion of recent onset seizures is known to be attributed to NCC in Taenia solium (T. solium) endemic areas where populations which neither raise pigs nor eat pig meat are also at risk. High prevalence of NCC causing epilepsy has been reported in the underdeveloped areas of Southeast Asia (SEA) however, only fragmentary information on its incidence is available in countries like Malaysia...
April 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28527268/-seroprevalence-and-risk-factors-of-cysticercosis-in-two-rural-communities-in-anzo%C3%A3-tegui-state-venezuela
#20
Manuel Toquero, Antonio Morocoima, Elizabeth Ferrer
INTRODUCTION: Cysticercosis is caused by Taenia solium cysticerci, which are located mainly in the central nervous system causing neurocysticercosis. In Venezuela, few epidemiological studies on this disease have been conducted. OBJECTIVE: To determine the seroprevalence and risk factors for cysticercosis in two rural communities in Anzoátegui state. MATERIAL AND METHODS: We conducted a survey to collect data on possible risk factors and signs and symptoms of the disease, and we took 182 samples in two communities, Boquerón and Punto Lindo...
April 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
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