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Calcification AND Blood pressure

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https://www.readbyqxmd.com/read/28614819/osteoprotegerin-is-the-strongest-predictor-for-progression-of-arterial-calcification-in-peritoneal-dialysis-patients
#1
Marcela Avila, Carmen Mora, María Del Carmen Prado, Miriam Zavala, Ramón Paniagua
BACKGROUND: Arterial calcification (AC) is frequent in patients with end stage renal disease and is also considered a risk factor for later morbidity and mortality. However, long-term factors associated with the process are not well known. We analyzed the trends over time of biomarkers related with development and progression of AC in incident patients on peritoneal dialysis (PD). METHODS: We performed a prospective study with 186 patients on PD followed up for 1 year...
June 15, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28612712/subcutaneous-injection-induced-cellulites
#2
Kao-Chi Cheng, Po-Tsung Huang, Chiu-Shong Liu, Wen-Yuan Lin
In the hospice ward where patients are in the terminal stages of cancer, it is common practice to give them a subcutaneous injection of pain relievers to reduce their pain and make them more comfortable. Most of these patients are elderly and have low blood pressure or poor veins, which often makes it difficult to inject them because of the calcification at previous injection sites. Thus, subcutaneous injections are a convenient way to maintain analgesia and patient comfort. Our patient, a 73-year-old aboriginal woman, was diagnosed with gastric adenocarcinoma and peritoneal carcinomatosis in March, 2004...
June 2017: BioMedicine
https://www.readbyqxmd.com/read/28611919/markers-of-arterial-stiffness-in-a-sample-of-lebanese-subjects-with-grade-i-essential-hypertension
#3
Samir Mallat, Abdo Jurjus, Tarek Bou Assi, Alice Jurjus, Ali Shams, Skye El Sayegh, Adel Berbari
OBJECTIVES: Arterial stiffness is becoming a major global condition associated with an increased risk of cardiovascular problems and death. Several markers have been linked to arterial stiffness. METHODS: To determine and evaluate these relations, anthropometric parameters (weight, height, and pulse rate), biochemical profile, and central and peripheral indices of arterial function were measured in 114 Lebanese subjects with Grade I essential hypertension. RESULTS: Age was associated with a higher pulse wave velocity (p = ...
2017: SAGE Open Medicine
https://www.readbyqxmd.com/read/28582505/subclinical-cardiovascular-disease-and-changes-in-self-reported-mobility-multi-ethnic-study-of-atherosclerosis-mesa
#4
Susan A Everson-Rose, Carlos F Mendes de Leon, Nicholas S Roetker, Pamela L Lutsey, Alvaro Alonso
BACKGROUND.: We examined associations of three markers of subclinical cardiovascular disease (CVD) (intimal-medial thickening (IMT); coronary artery calcification (CAC); and ankle-brachial index (ABI)) with changes in self-reported walking over time. METHODS.: Data were from 6,490 MESA participants (aged 45-84 years), free of clinical CVD at baseline. Outcomes, assessed four times over 11 years, included self-reported walking pace (none to striding pace; score, 0-4), and total walking time (minutes/week)...
June 3, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28580500/vascular-calcifications-on-the-preoperative-radiograph-harbinger-of-tourniquet-failure-in-patients-undergoing-total-knee-arthroplasty
#5
Julia Verena Woelfle-Roos, Laura Dautel, Benjamin Mayer, Ralf Bieger, Klaus-Dieter Woelfle, Heiko Reichel
OBJECTIVE: Vascular calcifications on the preoperative radiograph of patients scheduled for total knee arthroplasty (TKA) often give rise to concern, as their clinical relevance remains uncertain. The aim of this study was to investigate whether these vascular calcifications-especially medial artery calcifications (MACs), which increase arterial stiffness-were associated with tourniquet failure and thus with increased intraoperative blood loss. MATERIALS AND METHODS: A total of 765 patients who underwent primary TKA with a tourniquet (cuff pressure 350 mmHg) between 2009 and 2011 were screened for vascular calcifications on the preoperative radiograph...
June 5, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28558132/the-ratio-of-pericardial-to-subcutaneous-adipose-tissues-is-associated-with-insulin-resistance
#6
Amy C Alman, Steven R Smith, Robert H Eckel, John E Hokanson, Brant R Burkhardt, Preethi R Sudini, Yougui Wu, Irene E Schauer, Rocio I Pereira, Janet K Snell-Bergeon
OBJECTIVE: To examine the association between pericardial adipose tissue (PAT) and the ratio of PAT to subcutaneous adipose tissue (SAT) with insulin resistance in adults with and without type 1 diabetes (T1D). METHODS: Data for this report came from a substudy of the Coronary Artery Calcification in Type 1 Diabetes cohort (n = 83; 38 with T1D, 45 without T1D). Insulin resistance was measured by hyperinsulinemic-euglycemic clamp. Abdominal computed tomography (CT) was used to measure visceral adipose tissue (VAT) and SAT...
May 30, 2017: Obesity
https://www.readbyqxmd.com/read/28523594/the-relationship-between-coronary-artery-calcium-scores-and-left-atrium-size-in-hemodialysis-patients
#7
Ismail Baloglu, Kultigin Turkmen, H Zeki Tonbul, N Yılmaz Selcuk
PURPOSE: Hemodialysis patients have extremely increased cardiovascular mortality. The coronary artery calcification score (CACS) in uremic patients receiving hemodialysis reflects the severity of atherosclerotic vascular disease and predicts the cardiovascular events. In cardiac conditions, left atrial (LA) size has a prognostic importance. In this study, relationship between coronary artery calcification and left atrial size was investigated. METHODS: This was a cross-sectional study involving 32 hemodialysis patients (16 females, 16 males; mean age, 52...
May 18, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28497191/evaluation-of-the-coronary-circulation-and-calcification-in-children-on-regular-hemodialysis
#8
Mohammed Al-Biltagi, Maher Ahmed Abd ElHafez, Doaa Mohamed El Amrousy, Mohamed El-Gamasy, Hesham El-Serogy
BACKGROUND: The objective of this study was to evaluate the coronary circulation and calcification in children with end-stage renal disease (ESRD) on hemodialysis. METHODS: A total of 50 children with ESRD and 50 healthy controls were enrolled in the study. Cardiac functions and coronary blood flow were evaluated with conventional and tissue Doppler echocardiography. Coronary artery calcification (CAC) was evaluated using high-resolution multidetector computed tomography (CT)...
May 11, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28475443/evaluation-of-skin-perfusion-pressure-to-assess-refractory-foot-ulcers
#9
M Kawai, S Mihara, S Takahagi, K Iwamoto, T Hiragun, M Hide
OBJECTIVE: The number of patients with foot gangrene caused by critical ischaemia and severe infection is increasing significantly in developed countries. The measurement of perilesional skin blood flow by skin perfusion pressure (SPP) is useful to select the appropriate treatment of gangrenous lesions, in that it is not affected by calcifications of blood vessels. However, the prognosis of a foot ulcer may also be affected by the level of blood sugar and infections. This study aimed to validate the use of SPP in cases of foot gangrene and ulcers in patients with and without diabetes mellitus (DM) and infection...
May 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28468005/noninvasive-blood-pressure-measurement-in-maintenance-hemodialysis-patients-comparison-of-agreement-between-oscillometric-and-finger-cuff-methods
#10
Gaetano Alfano, Francesco Fontana, Gianni Cappelli
BACKGROUND: The Nexfin monitor is a device used for measuring arterial blood pressure (BP) continuously and noninvasively through finger-cuff technology. Since it was validated against the auscultatory method using a sphygmomanometer, the aim of this study was to test the ability of the Nexfin to evaluate brachial arterial pressure (BAP) in maintenance hemodialysis patients, quantifying accuracy and precision. METHODS: Forty hemodynamically stable hemodialysis patients underwent serial measurements of Nexfix arterial pressure (NAP) and BAP, respectively, through Nexfin and oscillometric devices...
May 4, 2017: Nephron
https://www.readbyqxmd.com/read/28460029/mitral-annular-calcification-progression-and-the-risk-of-atrial-fibrillation-results-from-mesa
#11
Wesley T O'Neal, Jimmy T Efird, Saman Nazarian, Alvaro Alonso, Erin D Michos, Moses Szklo, Susan R Heckbert, Elsayed Z Soliman
Aims: To determine if progression of mitral annular calcium (MAC) detected by cardiac computed tomography (CT) predicts incident atrial fibrillation (AF). Methods and results: This analysis included 5683 participants (mean age 64 ± 10 years; 52% women; 40% whites; 27% blacks; 21% Hispanics; 12% Chinese-Americans) from the Multi-Ethnic Study of Atherosclerosis. MAC was measured by cardiac CT at baseline and at a follow-up CT scan over a mean time of 2.4 ± 0...
April 27, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28458703/the-association-between-gallstone-disease-and-plaque-in-the-abdominopelvic-arteries
#12
Halil İbrahim Serin, Yunus Keser Yilmaz, Yaşar Turan, Ergin Arslan, Mustafa Fatih Erkoç, Aytaç Doğan, Mehmet Celikbilek
BACKGROUND: The aim of this study was to assess the atheromatous plaque, in the abdominopelvic arteries as a marker of cardiac risk in patients with or without gallstone disease (GD). MATERIALS AND METHODS: A total of 136 patients were enrolled in this cross-sectional study. Forty-eight patients had GD and the remaining 88 patients did not. The presence or absence of gallstones was noted during abdominal ultrasonography while vascular risk factors such as plaque formation, intima-media thickness, plaque calcification, mural thrombus, stenosis, aneurysm, and inflammation were recorded during an abdominopelvic computed tomography scan...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28455660/radial-artery-sclerostin-expression-in-chronic-kidney-disease-stage-5-predialysis-patients-a-cross-sectional-observational-study
#13
Hua Zhou, Min Yang, Min Li, Li Cui
PURPOSE: Bone metabolism disorder is often associated with cardiovascular calcification in patients with chronic kidney disease (CKD). Sclerostin, a novel candidate protein, has been identified to be involved in the bone-vascular axis. The aims of the current investigation were to assess vessel sclerostin expression and its relationship with circulating sclerostin levels. METHODS: A cross-sectional observational study was conducted from January 2012 to December 2014...
April 28, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28445258/renal-vascular-calcification-and-response-to-renal-nerve-denervation-in-resistant-hypertension
#14
Annemiek F Hoogerwaard, Mark R de Jong, Ahmet Adiyaman, Jaap Jan J Smit, Peter P H M Delnoy, Jan-Evert Heeg, Boudewijn A A M van Hasselt, Anand R Ramdat Misier, Arif Elvan
Renal sympathetic nerve denervation (RDN) is accepted as a treatment option for patients with resistant hypertension. However, results on decline in ambulatory blood pressure (BP) measurement (ABPM) are conflicting. The high rate of nonresponders may be related to increased systemic vascular stiffness rather than sympathetic overdrive. A single center, prospective registry including 26 patients with treatment resistant hypertension who underwent RDN at the Isala Hospital in the Netherlands. Renal perivascular calcium scores were obtained from noncontrast computed tomography scans...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28441695/increased-high-risk-coronary-plaque-burden-is-associated-with-arterial-stiffness-in-patients-with-type-2-diabetes-without-clinical-signs-of-coronary-artery-disease-a-computed-tomography-angiography-study
#15
Kristian L Funck, Esben Laugesen, Kristian Øvrehus, Jesper M Jensen, Bjarne L Nørgaard, Damini Dey, Troels K Hansen, Per L Poulsen
OBJECTIVES: Arterial stiffness and subclinical coronary atherosclerosis may yield valuable information on cardiovascular risk. We aimed to characterize coronary atherosclerosis in asymptomatic patients with type 2 diabetes and healthy controls and to investigate the association between baseline arterial stiffness and coronary plaque volumes after 5-year follow-up. METHODS: Data from 45 patients and 61 matched controls were available for coronary plaque assessment...
June 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28378290/associations-between-hip-bone-mineral-density-aortic-calcification-and-cardiac-workload-in-community-dwelling-older-australians
#16
A J Rodríguez, D Scott, A Hodge, D R English, G G Giles, P R Ebeling
In older adults, lower bone density in the proximal femur was associated with increased heart burden, and this association was linked to calcification in the aorta. These results were seen in women but not in men. PURPOSE: To determine whether there is an association between lower bone mineral density (BMD) and increased cardiac workload in older adults, and if this association was independent of abdominal aortic calcification (AAC). METHODS: Three hundred thirty-seven participants [mean ± SD age = 70 ± 5 years and BMI = 28 ± 5 kg/m(2), 61% females] had BMD determined by dual-energy X-ray absorptiometry and AAC determined by radiography...
April 4, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28360229/aortic-calcification-onset-and-progression-association-with-the-development-of-coronary-atherosclerosis
#17
Hagen Kälsch, Nils Lehmann, Susanne Moebus, Barbara Hoffmann, Andreas Stang, Karl-Heinz Jöckel, Raimund Erbel, Amir A Mahabadi
BACKGROUND: Thoracic aortic calcification (TAC) and coronary artery calcification (CAC) are markers of subclinical atherosclerosis and are associated with incident major cardiovascular events. We investigated major determinants for incidence and progression of TAC and the association between TAC and CAC incidence and progression. METHODS AND RESULTS: In a population-based cohort study, 3270 participants (aged 45-74 years, 53.1% women) received cardiac computed tomography at baseline and after a mean follow-up of 5...
March 30, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28349710/endovascular-devices-and-revascularization-techniques-for-limb-threatening-ischemia-in-individuals-with-diabetes
#18
Jayer Chung
Diabetes mellitus (DM) is a rapidly worsening global epidemic over the last thirty-five years. The increased prevalence of DM has changed the phenotypic expression of atherosclerotic limb threatening ischemia (LTI), resulting in an increase in lesions in the tibial vessels. These patients are also afflicted with peripheral neuropathy, foot deformities, and medial calcification of the vasculature. In response to the evolving phenotype of atherosclerosis, newer minimally invasive tools and techniques have been developed to improve the blood supply in LTI...
March 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28329057/coronary-artery-calcification-and-risk-of-cardiovascular-disease-and-death-among-patients-with-chronic-kidney-disease
#19
Jing Chen, Matthew J Budoff, Muredach P Reilly, Wei Yang, Sylvia E Rosas, Mahboob Rahman, Xiaoming Zhang, Jason A Roy, Eva Lustigova, Lisa Nessel, Virginia Ford, Dominic Raj, Anna C Porter, Elsayed Z Soliman, Jackson T Wright, Myles Wolf, Jiang He
Importance: Coronary artery calcification (CAC) is highly prevalent in dialysis-naive patients with chronic kidney disease (CKD). However, there are sparse data on the association of CAC with subsequent risk of cardiovascular disease and all-cause mortality in this population. Objective: To study the prospective association of CAC with risk of cardiovascular disease and all-cause mortality among dialysis-naive patients with CKD. Design, Setting, and Participants: The prospective Chronic Renal Insufficiency Cohort study recruited adults with an estimated glomerular filtration rate of 20 to 70 mL/min/1...
March 22, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28321403/hyperphosphatemia-and-hs-crp-initiate-the-coronary-artery-calcification-in-peritoneal-dialysis-patients
#20
Da Shang, Qionghong Xie, Bin Shang, Min Zhang, Li You, Chuan-Ming Hao, Tongying Zhu
Background. Coronary artery calcification (CAC) contributes to high risk of cardiocerebrovascular diseases in dialysis patients. However, the risk factors for CAC initiation in peritoneal dialysis (PD) patients are not known clearly. Methods. Adult patients with baseline CaCS = 0 and who were followed up for at least 3 years or until the conversion from absent to any measurable CAC detected were included in this observational cohort study. Binary logistic regression was performed to identify the risk factors for CAC initiation in PD patients...
2017: BioMed Research International
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