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Robotic sabr

Jeffrey Schlosser, Ren Hui Gong, Ralf Bruder, Achim Schweikard, Sungjune Jang, John Henrie, Aya Kamaya, Albert Koong, Daniel T Chang, Dimitre Hristov
PURPOSE: To present a system for robotic 4D ultrasound (US) imaging concurrent with radiotherapy beam delivery and estimate the proportion of liver stereotactic ablative body radiotherapy (SABR) cases in which robotic US image guidance can be deployed without interfering with clinically used VMAT beam configurations. METHODS: The image guidance hardware comprises a 4D US machine, an optical tracking system for measuring US probe pose, and a custom-designed robot for acquiring hands-free US volumes...
November 2016: Medical Physics
Charles A Kunos, Tracy M Sherertz, Mazen Mislmani, Rodney J Ellis, Simon S Lo, Steven E Waggoner, Kristine M Zanotti, Karin Herrmann, Robert L Debernardo
BACKGROUND: We conducted a phase I trial to determine the safety of systemic chemotherapy prior to abdominopelvic robotic stereotactic ablative radiotherapy (SABR) in women with persistent or recurrent gynecologic cancers. METHODS: Patients were assigned to dose-finding cohorts of day 1 carboplatin (AUC 2 or 4) and gemcitabine (600 or 800 mg/m(2)) followed by day 2 to day 4 Cyberknife SABR (8 Gy × three consecutive daily doses). Toxicities were graded prospectively by common terminology criteria for adverse events, version 4...
2015: Frontiers in Oncology
Dominique Mathieu, Marie-Pierre Campeau, Houda Bahig, Sandra Larrivée, Toni Vu, Louise Lambert, Caroline Lavoie, David Roberge, Robert Doucet, Jean-François Carrier, Andrei Gorgos, Bernard Fortin, Edith Filion
PURPOSE: The purpose of this study was to prospectively evaluate the quality of life (QoL) and pulmonary function of patients with early-stage non-small cell lung cancer treated with robotic stereotactic ablative radiation therapy (SABR). METHODS AND MATERIALS: Eligible patients all had histologically confirmed stage I non-small cell lung cancer and were not surgical candidates because of poor pulmonary function, comorbidities, or refusal of surgery. SABR was delivered at a median dose of 60 Gy in 3 fractions for peripheral tumors and 50 Gy in 4 or 5 fractions for central tumors...
July 2015: Practical Radiation Oncology
Constantine Mantz
PURPOSE/OBJECTIVE(S): Herein, we report the results of an IRB-approved phase II trial of Varian Trilogy/TrueBeam-based stereotactic ablative body radiotherapy (SABR) monotherapy for low-risk prostate cancer using the Calypso(®) System to provide real-time electromagnetic tracking of the prostate's position during treatment delivery. MATERIALS/METHODS: A total of 102 low-risk patients completed protocol treatment between January 2007 and May 2009. A total dose of 40...
2014: Frontiers in Oncology
Mazen Mislmani, Heidi Frasure, Somu Suppiah, Jeffrey Fabien, Simon S Lo, Robert Debernardo, Charles A Kunos
AIMS: The aim of this study was to assess acute and subacacute gastrointestinal toxicity after fractionated stereotactic ablative radiotherapy (SABR) in women having recurrent gynecological cancers in the upper abdomen. MATERIALS & METHODS: In total, 34 women underwent upper abdominal SABR (24 Gy/three divided 8 Gy consecutive daily doses) using a robotic Cyberknife® (Accuray, CA, USA) platform. Volumes of the duodenum receiving 10% increments of the prescription dose were associated to post-therapy gastrointestinal toxicities using binary logistic regression analyses...
February 2014: Future Oncology
Iris C Gibbs, Billy W Loo
Stereotactic ablative radiotherapy (SABR) has emerged as a promising treatment for early stage non-small cell lung cancer, particularly for patients unable to tolerate surgical resection. High rates of local tumor control have been demonstrated with acceptable toxicity and the practical advantage of a short course of treatment. The CyberKnife image-guided robotic radiosurgery system has unique technical characteristics that make it well suited for SABR of tumors that move with breathing, including lung tumors...
December 2010: Technology in Cancer Research & Treatment
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