Roni Rosen, Felipe F Quezada-Diaz, Mithat Gönen, Georgios Karagkounis, Maria Widmar, Iris H Wei, J Joshua Smith, Garrett M Nash, Martin R Weiser, Philip B Paty, Andrea Cercek, Paul B Romesser, Francisco Sanchez-Vega, Mohammad Adileh, Diana Roth O'Brien, Carla Hajj, Vonetta M Williams, Marina Shcherba, Ping Gu, Christopher Crane, Leonard B Saltz, Julio Garcia Aguilar, Emmanouil Pappou
Background: Abdominoperineal resection (APR) has been advocated for persistent or recurrent disease after failure of chemoradiation (CRT) for anal squamous cell cancer (SCC). Treatment with salvage APR can potentially achieve a cure. This study aimed to analyze oncological outcomes for salvage APR in a recent time period at a comprehensive cancer center. Methods: A retrospective review of all patients who underwent APR for biopsy-proven persistent or recurrent anal SCC between 1 January 2007 and 31 December 2020 was performed...
April 9, 2024: Journal of Clinical Medicine